Retraction
Norepinephrine Protects Cerebral Autoregulation and Reduces Hippocampal Necrosis after Traumatic Brain Injury via Blockade of ERK MAPK and IL-6 in Juvenile Pigs
Paper Information
Record ID:
36855
Author(s):
Journal:
Publication Date:
November 23, 2015
Retraction Date:
April 29, 2022
(3.6 years years ago)
Subjects:
Institutions:
- Department of Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, Pennsylvania
- Department of Pharmacology, University of Pennsylvania, Philadelphia, Pennsylvania
- Department of Anesthesiology, Pediatrics, and Neurological Surgery, and Harborview Injury Prevention and Research Center, University of Washington, Seattle, Washington
Country:
🇺🇸 United StatesArticle Type:
Publisher:
Mary Ann Liebert
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1089/neu.2015.4290.retractAdditional Notes:
William Armstead has ORI finding of misconduct; see https://ori.hhs.gov/content/case-summary-armstead-william-m
Citations (36)
36
Total Citations2
Post-Retraction(5.6%)
33
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
1
Within 30 days
1
Within 1 year
1
After 2+ years
1007
Days since retraction (latest)
The Intricacy of Subsequent Pathway Resulting from Traumatic Brain Injury: Pathophysiology and Possible Interventions
Mohit Kumar, Jasmine Chaudhary, Akash Jain
Current Behavioral Neuroscience Reports
Published: Jan 2025
1 citation
1 citation
1007 days after retraction
<i>Retraction of:</i> Inhaled Nitric Oxide Protects Cerebral Autoregulation and Reduces Hippocampal Neuronal Cell Necrosis after Traumatic Brain Injury in Newborn and Juvenile Pigs (DOI: 10.1089/neu.2018.5824)
Unknown Authors
Journal of Neurotrauma
Open Access
Published: May 2022
2 citations
2 citations
4 days after retraction
<i>Retraction of:</i> Sex and Age Differences in Epinephrine Mechanisms and Outcomes after Brain Injury (DOI: 10.1089/neu.2016.4770)
Unknown Authors
Journal of Neurotrauma
Open Access
Published: Apr 2022
2 citations
2 citations
Same day as retraction
Cerebral blood flow self-regulation in depression
Min Liu, Enling He, Xiyao Fu et al. (6 authors)
Journal of Affective Disorders
Open Access
Published: Jan 2022
18 citations
18 citations
106 days before retraction
Regulation of the Cerebral Circulation During Development
Raymond C. Koehler
Comprehensive physiology
Published: Oct 2021
210 days before retraction
Regulation of the Cerebral Circulation During Development
Raymond C. Koehler
Comprehensive physiology
Open Access
Published: Sep 2021
6 citations
6 citations
218 days before retraction
Valproic Acid Reduces Vasospasm through Modulation of Akt Phosphorylation and Attenuates Neuronal Apoptosis in Subarachnoid Hemorrhage Rats
Chieh‐Hsin Wu, Yi-Cheng Tsai, Tai‐Hsin Tsai et al. (7 authors)
International Journal of Molecular Sciences
Open Access
Published: Jun 2021
13 citations
13 citations
332 days before retraction
Compromised Dynamic Cerebral Autoregulation in Patients With Central Disorders of Hypersomnolence
Fang Deng, Yanan Zhang, Ran Zhang et al. (8 authors)
Frontiers in Neurology
Open Access
Published: Mar 2021
5 citations
5 citations
414 days before retraction
Novel Synthetic and Natural Therapies for Traumatic Brain Injury
Denise Battaglini, Dorota Siwicka-Gieroba, Patrícia R. M. Rocco et al. (10 authors)
Current Neuropharmacology
Open Access
Published: Feb 2021
20 citations
20 citations
427 days before retraction
The cerebrovascular response to norepinephrine: A scoping systematic review of the animal and human literature
Logan Froese, Joshua Dian, Alwyn Gomez et al. (5 authors)
Pharmacology Research & Perspectives
Open Access
Published: Sep 2020
34 citations
34 citations
583 days before retraction
Effects of Norepinephrine, Propofol, and Hemoglobin Concentration on Dynamic Measurements of Cerebrovascular Reactivity in Acute Brain Injury
Samuel P. Klein, Steffen Fieuws, Geert Meyfroidt et al. (4 authors)
Journal of Neurotrauma
Open Access
Published: Jul 2020
19 citations
19 citations
666 days before retraction
Das Schädel-Hirn-Trauma im Erwachsenenalter
Paul Hagebusch, Andreas Pingel, Frank Kandziora et al. (5 authors)
Notfallmedizin up2date
Open Access
Published: Feb 2020
6 citations
6 citations
791 days before retraction
Central Noradrenergic Agonists in the Treatment of Ischemic Stroke—an Overview
Zohara Sternberg, Bernhard Schaller
Translational Stroke Research
Published: Jul 2019
47 citations
47 citations
1014 days before retraction
Cerebral Perfusion Pressure Directed-Therapy Modulates Cardiac Dysfunction After Traumatic Brain Injury to Influence Cerebral Autoregulation in Pigs
William M. Armstead, Monica S. Vavilala
Neurocritical Care
Open Access
Published: May 2019
5 citations
5 citations
1074 days before retraction
Coenzyme Q10 Protects Astrocytes from Ultraviolet B-Induced Damage Through Inhibition of ERK 1/2 Pathway Overexpression
Qi Zhao, Yanmei Ma, Jing Li et al. (7 authors)
Neurochemical Research
Published: May 2019
12 citations
12 citations
1080 days before retraction
Translational approach towards determining the role of cerebral autoregulation in outcome after traumatic brain injury
William M. Armstead, Monica S. Vavilala
Experimental Neurology
Open Access
Published: Mar 2019
16 citations
16 citations
1129 days before retraction
Improving Understanding and Outcomes of Traumatic Brain Injury Using Bidirectional Translational Research
William M. Armstead, Monica S. Vavilala
Journal of Neurotrauma
Open Access
Published: Mar 2019
15 citations
15 citations
1151 days before retraction
Sex differences in pediatric traumatic brain injury
Sheryl E. Arambula, Erin L. Reinl, Nagat El Demerdash et al. (5 authors)
Experimental Neurology
Open Access
Published: Mar 2019
58 citations
58 citations
1154 days before retraction
Temporal Course of Cerebral Autoregulation in Patients With Narcolepsy Type 1: Two Case Reports
Zhen‐Ni Guo, Xin Sun, Yingkai Zhao et al. (7 authors)
Frontiers in Neurology
Open Access
Published: Jan 2019
1 citation
1 citation
1205 days before retraction
Inhaled nitric oxide protects cerebral autoregulation through prevention of impairment of ATP and calcium sensitive K channel mediated cerebrovasodilation after traumatic brain injury
Philip Pastor, Victor Prado Curvêllo, Hugh Hekierski et al. (4 authors)
Brain Research
Published: Jan 2019
19 citations
19 citations
1208 days before retraction
The potential roles of dopamine in traumatic brain injury: a preclinical and clinical update.
Yu‐Long Lan, Shao Li, Jiacheng Lou et al. (5 authors)
PubMed
Published: Jan 2019
42 citations
42 citations
1214 days before retraction
RETRACTED ARTICLE: Inhaled Nitric Oxide Protects Cerebral Autoregulation and Reduces Hippocampal Necrosis After Traumatic Brain Injury Through Inhibition of ET-1, ERK MAPK and IL-6 Upregulation in Pigs
Victor Prado Curvêllo, Philip Pastor, Hugh Hekierski et al. (4 authors)
Neurocritical Care
Published: Nov 2018
26 citations
26 citations
1275 days before retraction
Circular Ribonucleic Acid Expression Profile in Mouse Cortex after Traumatic Brain Injury
Youjing Jiang, Shuqiang Cao, Linbo Gao et al. (14 authors)
Journal of Neurotrauma
Published: Sep 2018
37 citations
37 citations
1309 days before retraction
Antioxidant Melatonin: Potential Functions in Improving Cerebral Autoregulation After Subarachnoid Hemorrhage
Zhen‐Ni Guo, Hang Jin, Huijie Sun et al. (8 authors)
Frontiers in Physiology
Open Access
Published: Aug 2018
23 citations
23 citations
1351 days before retraction
Establishment of a precise novel brain trauma model in a large animal based on injury of the cerebral motor cortex
Jipeng Jiang, Chen Dai, Xuegang Niu et al. (12 authors)
Journal of Neuroscience Methods
Published: Jun 2018
12 citations
12 citations
1402 days before retraction
Synergistic Inhibition of ERK1/2 and JNK, Not p38, Phosphorylation Ameliorates Neuronal Damages After Traumatic Brain Injury
Saurav Bhowmick, Veera D’Mello, P. M. Abdul‐Muneer
Molecular Neurobiology
Published: Jun 2018
39 citations
39 citations
1423 days before retraction
RETRACTED ARTICLE: Release of IL-6 After Stroke Contributes to Impaired Cerebral Autoregulation and Hippocampal Neuronal Necrosis Through NMDA Receptor Activation and Upregulation of ET-1 and JNK
William M. Armstead, Hugh Hekierski, Philip Pastor et al. (6 authors)
Translational Stroke Research
Published: Feb 2018
62 citations
62 citations
1526 days before retraction
Large animal models of traumatic brain injury
Junxi Dai, Yanbin Ma, Nanyang Le et al. (5 authors)
International Journal of Neuroscience
Published: Sep 2017
48 citations
48 citations
1684 days before retraction
RETRACTED: Dopamine protects cerebral autoregulation and prevents hippocampal necrosis after traumatic brain injury via block of ERK MAPK in juvenile pigs
Victor Prado Curvêllo, Hugh Hekierski, Philip Pastor et al. (5 authors)
Brain Research
Open Access
Published: Jun 2017
22 citations
22 citations
1778 days before retraction
K channel impairment determines sex and age differences in epinephrine‐mediated outcomes after brain injury
William M. Armstead, John Riley, Monica S. Vavilala
Journal of Neuroscience Research
Open Access
Published: Apr 2017
7 citations
7 citations
1844 days before retraction
RETRACTED ARTICLE: Sex and age differences in phenylephrine mechanisms and outcomes after piglet brain injury
Victor Prado Curvêllo, Hugh Hekierski, John Riley et al. (5 authors)
Pediatric Research
Open Access
Published: Mar 2017
14 citations
14 citations
1857 days before retraction
Tripartite Stratification of the Glasgow Coma Scale in Children with Severe Traumatic Brain Injury and Mortality: An Analysis from a Multi-Center Comparative Effectiveness Study
Sarah Murphy, Neal J. Thomas, Shira J. Gertz et al. (10 authors)
Journal of Neurotrauma
Open Access
Published: Jan 2017
37 citations
37 citations
1940 days before retraction
Salvianolic acid A attenuates early brain injury after subarachnoid hemorrhage in rats by regulating ERK/P38/Nrf2 signaling.
Xiang Gu, Chengzhang Zheng, Qiaoying Zheng et al. (7 authors)
PubMed
Published: Jan 2017
25 citations
25 citations
1944 days before retraction
<b><i>Retracted:</i></b>Sex and Age Differences in Epinephrine Mechanisms and Outcomes after Brain Injury
William M. Armstead, John Riley, Monica S. Vavilala
Journal of Neurotrauma
Open Access
Published: Dec 2016
26 citations
26 citations
1973 days before retraction
Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling: Pathomechanisms, perspectives, and therapeutic implications
Péter Tóth, Nikolett Szarka, Eszter Farkas et al. (10 authors)
AJP Heart and Circulatory Physiology
Open Access
Published: Sep 2016
103 citations
103 citations
2056 days before retraction
Cerebral Blood Flow Autoregulation and Dysautoregulation
William M. Armstead
Anesthesiology Clinics
Open Access
Published: Aug 2016
264 citations
264 citations
2088 days before retraction
Quick Stats
Total Citations:
36
Years Since Retraction:
3.6 years
Open Access:
Yes
Last Checked:
Jul 24, 2025