Expression of concern

Use of ivermectin in the treatment of Covid-19: A pilot trial

Paper Information

Record ID:

37231

Author(s):

Henrique Pott-Junior
Monica Maria Bastos Paolielloo
Alice de Queiroz Constantino Miguel
Anderson Ferreira da Cunha
Caio Cesar de Melo Freire
Fábio Fernandes Neves
Lucimar Retto da Silva de Avó
Meliza Goi Roscani
Sigrid De Sousa dos Santos
Silvana Gama Florêncio Chach

Journal:

Toxicology Reports ( Elsevier )

Publication Date:

March 09, 2021

Retraction Date:

December 17, 2021 (3.9 years years ago)

Subjects:

Broad Categories:
Medicine

Specific Fields:
Medicine - Infectious Disease Medicine - Pharmacology

Institutions:

Countries:

🇧🇷 Brazil 🇺🇸 United States

Article Type:

Clinical Study

Publisher:

Elsevier

Open Access:

Yes

DOI:

10.1016/j.toxrep.2021.03.003

PubMed ID:

33723507

Retraction PubMed ID:

34934634

Expression of concern Details

Retraction Reasons:

Nature of Retraction:

Expression of concern

Retraction Notice:

10.1016/j.toxrep.2021.12.007

Additional Notes:

the entire issue is subject to an expression of concern

Citations (45)

45

Total Citations

18

Post-Retraction
(40.0%)

27

Pre-Retraction

0

Same Day

Post-Retraction Citation Analysis

3 Within 30 days

12 Within 1 year

3 After 2+ years

1259 Days since retraction (latest)

Drug treatments for mild or moderate covid-19: systematic review and network meta-analysis

Sara Ibrahim, Reed Siemieniuk, María José Oliveros et al. (42 authors)

BMJ Open Access

Published: May 2025
1 citation

1259 days after retraction

Clinical Experience With Ivermectin and Nitazoxanide in the Management of COVID-19 Among Mexican Out- and Inpatients

Jorge García-Méndez, Luis E. Fernández-Garza, Karen Vallejo-Oviedo et al. (10 authors)

Cureus Open Access

Published: Nov 2024

1075 days after retraction

Ivermectin for treatment of COVID-19: A systematic review and meta-analysis

Zhilong Song, Senyuan Shi, Yongli Zhang

Heliyon Open Access

Published: Mar 2024
8 citations

805 days after retraction

Against Authority: The Bioethics of Ivermectin Use for COVID-19 Infection

Vasile Astărăstoae, Liliana Rogozea

American Journal of Therapeutics

Published: Apr 2023

486 days after retraction

Outcome of Ivermectin in Cancer Treatment: An Experience in Loja-Ecuador

Yuliana Jiménez-Gaona, Oscar Vivanco-Galván, Gonzalo Morales-Larreategui et al. (5 authors)

Nursing Reports Open Access

Published: Feb 2023
2 citations

432 days after retraction

COVID-19: How Effective Are the Repurposed Drugs and Novel Agents in Treating the Infection?

Chow Suet-May, Kuok Sin-Yee, Lee Jia-Qing et al. (10 authors)

Sudan Journal of Medical Sciences Open Access

Published: Dec 2022

378 days after retraction

Ivermectin compared with placebo in the clinical course in Mexican patients with asymptomatic and mild COVID-19: a randomized clinical trial

Carmen de la Rocha, Marco A. Cid-López, Blanca I. Venegas-López et al. (21 authors)

BMC Infectious Diseases Open Access

Published: Dec 2022
9 citations

356 days after retraction

Repurposing Potential of the Antiparasitic Agent Ivermectin for the Treatment and/or Prophylaxis of COVID-19

Hoda Awad, Basmala Hassan, Sara Dweek et al. (6 authors)

Pharmaceuticals Open Access

Published: Aug 2022
6 citations

253 days after retraction

Systematic review and meta-analysis of ivermectin for treatment of COVID-19: evidence beyond the hype

Milena Soriano Marcolino, Karina Cardoso Meira, Nathália Sernizon Guimarães et al. (9 authors)

BMC Infectious Diseases Open Access

Published: Jul 2022
33 citations

218 days after retraction

Antiparasitic Drugs against SARS-CoV-2: A Comprehensive Literature Survey

Estefanía Calvo‐Álvarez, Maria Dolci, Federica Perego et al. (11 authors)

Microorganisms Open Access

Published: Jun 2022
2 citations

189 days after retraction

Ivermectin for preventing and treating COVID-19

Maria Popp, Stefanie Reis, Selina Schießer et al. (10 authors)

Cochrane library Open Access

Published: Jun 2022
158 citations

186 days after retraction

Ivermectin under scrutiny: a systematic review and meta-analysis of efficacy and possible sources of controversies in COVID-19 patients

Arman Shafiee, Mohammad Mobin Teymouri Athar, Omid Kohandel Gargari et al. (6 authors)

Virology Journal Open Access

Published: Jun 2022
21 citations

178 days after retraction

Dose-Dependent Ivermectin Effect on COVID-19 Polymerase Chain Reaction Status

Nirmeen A. Sabry, Yasser Fouad, Mohamed AbdAllah et al. (5 authors)

American Journal of Therapeutics

Published: Mar 2022

101 days after retraction

Removal of ivermectin from aqueous media using commercial, bentonite-based organophilic clay as an adsorbent

Ramiro Picoli Nippes, Paula Derksen Macruz, Thaísa Frossard Coslop et al. (5 authors)

Clay Minerals Open Access

Published: Mar 2022
9 citations

74 days after retraction

Ivermectin in COVID-19 Management: What is the Current Evidence?

Madhavi Eerike, Gerard Marshall Raj, Rekha Priyadarshini et al. (6 authors)

Infectious Disorders - Drug Targets

Published: Jan 2022
1 citation

33 days after retraction

Systematic Review and Meta-Analysis of Ivermectin for Treatment of COVID-19: Evidence Beyond the Hype

Milena Soriano Marcolino, Karina Cardoso Meira, Victor Schulthais Chagas et al. (9 authors)

SSRN Electronic Journal Open Access

Published: Jan 2022
2 citations

15 days after retraction

Multipurpose Drugs Active Against Both Plasmodium spp. and Microorganisms: Potential Application for New Drug Development

Takuro Endo, Hitoshi Takemae, Indu Sharma et al. (4 authors)

Frontiers in Cellular and Infection Microbiology Open Access

Published: Dec 2021
2 citations

7 days after retraction

Bias as a source of inconsistency in ivermectin trials for COVID-19: A systematic review. Ivermectin's suggested benefits are mainly based on potentially biased results

Ariel Izcovich, Sasha Peiris, Martín Ragusa et al. (7 authors)

Journal of Clinical Epidemiology Open Access

Published: Dec 2021
26 citations

1 days after retraction

ESCMID COVID-19 living guidelines: drug treatment and clinical management

Michele Bartoletti, Özlem Kurt Azap, Aleksandra Barać et al. (14 authors)

Clinical Microbiology and Infection Open Access

Published: Nov 2021
145 citations

25 days before retraction

Coronavirus Disease (COVID-19) Control between Drug Repurposing and Vaccination: A Comprehensive Overview

Ahmed A. Al‐Karmalawy, Raya Soltane, Ayman Abo Elmaaty et al. (11 authors)

Vaccines Open Access

Published: Nov 2021
39 citations

35 days before retraction

Identification and Development of Therapeutics for COVID-19

Halie M. Rando, Nils Wellhausen, Soumita Ghosh et al. (23 authors)

mSystems Open Access

Published: Nov 2021
19 citations

45 days before retraction

Darunavir ethanolate: Repurposing an anti-HIV drug in COVID-19 treatment

Vivek P. Chavda, Normi D. Gajjar, Nirav Shah et al. (4 authors)

European Journal of Medicinal Chemistry Reports Open Access

Published: Oct 2021
38 citations

56 days before retraction

A Review of the Antiviral Activity of Ivermectin and Its Use in the Treatment of Coronavirus Disease-2019

Christabel Nang’andu Hikaambo, Martin Kampamba, Fernando Bwalya et al. (9 authors)

Epidemiology - Open Journal Open Access

Published: Oct 2021
2 citations

57 days before retraction

The uses and abuses of systematic reviews

Edmund J. Fordham, Theresa A Lawrie, Katherine S. MacGilchrist et al. (4 authors)

Unknown Journal

Published: Oct 2021
2 citations

71 days before retraction

Efficacy and safety of ivermectin for COVID-19

Alok Singh, Pranav G. Sheth, Suryaprakash Dhaneria et al. (4 authors)

Asian Pacific Journal of Tropical Medicine Open Access

Published: Oct 2021
3 citations

77 days before retraction

Uso da ivermectina no tratamento da COVID-19 em humanos: revisão integrativa

Nicoli Maciel, Vivian B. Neis, Adrielli Tenfen

Research Society and Development Open Access

Published: Oct 2021

77 days before retraction

A short study comparing countries on the quality of response to the Covid-19 pandemic

Thilakam Venkatapathi, Murugesan Venkatapathi

arXiv (Cornell University)

Published: Sep 2021

78 days before retraction

Efficacy and safety of ivermectin for the treatment of COVID-19: a systematic review and meta-analysis

Jiawen Deng, Fangwen Zhou, Saif Ali et al. (7 authors)

QJM Open Access

Published: Sep 2021
34 citations

87 days before retraction

Immune response (IgG) following full inoculation with BNT162b2 COVID‑19 mRNA among healthcare professionals

Aristidis Tsatsakis, Elena Vakonaki, Manolis Tzatzarakis et al. (18 authors)

International Journal of Molecular Medicine Open Access

Published: Sep 2021
21 citations

95 days before retraction

Ivermectin: Potential Repurposing of a Versatile Antiparasitic as a Novel Anticancer

Alfonso Dueñas‐González, Mandy Juárez-Rodríguez

IntechOpen eBooks Open Access

Published: Sep 2021
1 citation

99 days before retraction

Use and abuses of systematic reviews

Edmund J. Fordham, Theresa A Lawrie, Katherine S. MacGilchrist et al. (4 authors)

Unknown Journal

Published: Sep 2021

105 days before retraction

Major Insights in Dynamics of Host Response to SARS-CoV-2: Impacts and Challenges

Al Hakim, Md. Mahbub Hasan, Mahmudul Hasan et al. (8 authors)

Frontiers in Microbiology Open Access

Published: Aug 2021
11 citations

114 days before retraction

Bias as a source of inconsistency in ivermectin trials for COVID-19: A systematic review

Ariel Izcovich, Sasha Peiris, Martín Ragusa et al. (7 authors)

medRxiv (Cold Spring Harbor Laboratory) Open Access

Published: Aug 2021
2 citations

118 days before retraction

Structural deformability induced in proteins of potential interest associated with COVID-19 by binding of homologues present in ivermectin: Comparative study based in elastic networks models

Lenin González-Paz, María Laura Hurtado-León, Carla Lossada et al. (9 authors)

Journal of Molecular Liquids Open Access

Published: Aug 2021
11 citations

122 days before retraction

Aumento do consumo de ivermectina no Brasil e o risco de surtos de escabiose

Alfredo Dias de Oliveira‐Filho, Lucas Tenorio Carmo do Nascimento Bezerra, Natalia da Silva Alves et al. (4 authors)

Research Society and Development

Published: Aug 2021
6 citations

124 days before retraction

Ivermectin for preventing and treating COVID-19

Maria Popp, Miriam Stegemann, Maria‐Inti Metzendorf et al. (8 authors)

Cochrane library Open Access

Published: Jul 2021
90 citations

142 days before retraction

Current Use of Ivermectin in Dermatology, Tropical Medicine, and COVID-19

Sinu Rose Mathachan, Kabir Sardana, Ananta Khurana

Indian Dermatology Online Journal Open Access

Published: Jul 2021
17 citations

169 days before retraction

Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

Andrew Bryant, Theresa A Lawrie, Therese Dowswell et al. (7 authors)

American Journal of Therapeutics Open Access

Published: Jun 2021
233 citations

181 days before retraction

Application of carbohydrates in approved small molecule drugs: A review

Hongfei Jiang, Xiaofei Qin, Qi Wang et al. (11 authors)

European Journal of Medicinal Chemistry

Published: Jun 2021
64 citations

183 days before retraction

Ivermectin and outcomes from Covid‐19 pneumonia: A systematic review and meta‐analysis of randomized clinical trial studies

Timotius Ivan Hariyanto, Devina Adella Halim, Jane Rosalind et al. (5 authors)

Reviews in Medical Virology Open Access

Published: Jun 2021
44 citations

194 days before retraction

Clinical study evaluating the efficacy of ivermectin in COVID‐19 treatment: A randomized controlled study

Sherief Abd‐Elsalam, Rasha A. Abdel Noor, Rehab Badawi et al. (16 authors)

Journal of Medical Virology Open Access

Published: Jun 2021
97 citations

198 days before retraction

Macrolides: From Toxins to Therapeutics

Kiersten D. Lenz, Katja E. Klosterman, Harshini Mukundan et al. (4 authors)

Toxins Open Access

Published: May 2021
92 citations

219 days before retraction

An Updated Systematic Review and Meta-Analysis of Mortality, Need for ICU admission, Use of Mechanical Ventilation, Adverse effects and other Clinical Outcomes of Ivermectin Treatment in COVID-19 Patients

Smruti Karale, Vikas Bansal, Janaki Makadia et al. (12 authors)

medRxiv (Cold Spring Harbor Laboratory)

Published: May 2021
15 citations

227 days before retraction

Identification and Development of Therapeutics for COVID-19.

Halie M. Rando, Nils Wellhausen, Soumita Ghosh et al. (23 authors)

PubMed

Published: Mar 2021
1 citation

289 days before retraction

RETRACTED: Why are we vaccinating children against COVID-19?

Ronald N. Kostoff, Daniela Călina, Darja Kanduc et al. (7 authors)

Toxicology Reports Open Access

Published: Jan 2021
35 citations

350 days before retraction

Related Records

This article has multiple records in the database due to different notices:

Record #37123

May 02, 2022

Retraction

Quick Stats

Total Citations: 45

Years Since Retraction: 3.9 years

Open Access: Yes

Last Checked: Jul 24, 2025

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