Expression of concern
The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function
Paper Information
Record ID:
37933
Author(s):
Publication Date:
March 23, 2009
Retraction Date:
June 23, 2022
(3.4 years years ago)
Subjects:
Institutions:
Country:
🇫🇷 FranceArticle Type:
Publisher:
PLoS
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Expression of concern Details
Retraction Reasons:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1371/journal.pone.0270655Citations (198)
198
Total Citations49
Post-Retraction(24.7%)
148
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
0
Within 30 days
22
Within 1 year
18
After 2+ years
1071
Days since retraction (latest)
Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis
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Super-enhancer-associated MEIS1 promotes transcriptional dysregulation in Ewing sarcoma in co-operation with EWS-FLI1
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63 citations
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Nature Communications
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64 citations
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66 citations
66 citations
1430 days before retraction
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6 citations
6 citations
1438 days before retraction
PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation
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12 citations
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668 citations
668 citations
1449 days before retraction
<scp>EWS</scp>‐<scp>FLI</scp>1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma
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Cancer Science
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23 citations
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Imaging dynamic and selective low-complexity domain interactions that control gene transcription
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Science
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Published: Jun 2018
926 citations
926 citations
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Disruption of mammalian SWI/SNF and polycomb complexes in human sarcomas: mechanisms and therapeutic opportunities
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Published: Jan 2018
34 citations
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The Function of Wnt/beta-catenin Signaling in Ewing Sarcoma and its Contribution to Pathogenesis
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1634 days before retraction
MK-STYX
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1658 days before retraction
Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma
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PLoS ONE
Open Access
Published: Nov 2017
55 citations
55 citations
1695 days before retraction
Dynamic and Selective Low-Complexity Domain Interactions Revealed by Live-Cell Single-Molecule Imaging
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bioRxiv (Cold Spring Harbor Laboratory)
Open Access
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9 citations
9 citations
1702 days before retraction
Gene Regulatory Enhancers with Evolutionarily Conserved Activity Are More Pleiotropic than Those with Species-Specific Activity
Alexandra E. Fish, Ling Chen, John A. Capra
Genome Biology and Evolution
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35 citations
35 citations
1741 days before retraction
Funktionelle Genomik des Ewing‑Sarkoms
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Der Pathologe
Published: Aug 2017
1760 days before retraction
Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth
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Published: Aug 2017
77 citations
77 citations
1760 days before retraction
Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain
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Published: Aug 2017
422 citations
422 citations
1763 days before retraction
Biomarkers of Osteosarcoma, Chondrosarcoma, and Ewing Sarcoma
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Frontiers in Pharmacology
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98 citations
98 citations
1903 days before retraction
A genomic view of short tandem repeats
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Current Opinion in Genetics & Development
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142 citations
142 citations
1954 days before retraction
C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells
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Oncotarget
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Published: Jan 2017
16 citations
16 citations
1973 days before retraction
BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcoma
Sudan N. Loganathan, Nan Tang, Jonathan T. Fleming et al. (8 authors)
Oncotarget
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Published: Jun 2016
43 citations
43 citations
2213 days before retraction
FATE1: Contributor to Tumor Cell Fitness and Example of an Oncogene-Activated Cancer Testis Antigen
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Unknown Journal
Published: May 2016
2244 days before retraction
Coopération entre mutation somatique et variant génétique de susceptibilité dans le sarcome d’Ewing
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médecine/sciences
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Published: Apr 2016
2 citations
2 citations
2274 days before retraction
Identification of Mithramycin Analogues with Improved Targeting of the EWS-FLI1 Transcription Factor
Christy Osgood, Nichole Maloney, Christopher G. Kidd et al. (20 authors)
Clinical Cancer Research
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Published: Mar 2016
64 citations
64 citations
2290 days before retraction
Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells
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Journal of Biological Chemistry
Open Access
Published: Mar 2016
32 citations
32 citations
2296 days before retraction
Analysis of Genomic Sequence Motifs for Deciphering Transcription Factor Binding and Transcriptional Regulation in Eukaryotic Cells
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Frontiers in Genetics
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Published: Feb 2016
145 citations
145 citations
2312 days before retraction
Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition <i>via</i> LSD1 targeting
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Oncotarget
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65 citations
65 citations
2333 days before retraction
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237 citations
237 citations
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Cooperation between somatic mutations and germline susceptibility variants in tumorigenesis – a dangerous liaison
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12 citations
12 citations
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7 citations
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The regulation and role of MS1 in the cardiac stress response
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Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite
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Published: Jul 2015
178 citations
178 citations
2523 days before retraction
EWS/FLI1 Target Genes and Therapeutic Opportunities in Ewing Sarcoma
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Frontiers in Oncology
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63 citations
63 citations
2530 days before retraction
Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes
Laurens G.L. Sand, Károly Szuhai, Pancras C.W. Hogendoorn
International Journal of Molecular Sciences
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64 citations
64 citations
2534 days before retraction
EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma
John Fadul, Russell Bell, Laura Hoffman et al. (6 authors)
Genes & Cancer
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43 citations
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2624 days before retraction
Translocations in Ewing Sarcoma
Jason M. Tanner, Stephen L. Lessnick
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1 citation
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2730 days before retraction
Ewing Sarcoma
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2730 days before retraction
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis
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90 citations
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2776 days before retraction
EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma
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407 citations
407 citations
2793 days before retraction
Biology of Ewing sarcoma
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1 citation
1 citation
2840 days before retraction
Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy
Heinrich Kovar
Expert Opinion on Therapeutic Targets
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68 citations
68 citations
2857 days before retraction
Clinical and Biochemical Function of Polymorphic NR0B1 GGAA-Microsatellites in Ewing Sarcoma: A Report from the Children's Oncology Group
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39 citations
39 citations
2879 days before retraction
RUNX3 Facilitates Growth of Ewing Sarcoma Cells
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Journal of Cellular Physiology
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18 citations
18 citations
2968 days before retraction
Dealing with complexity of biological systems: from data to models
Andreï Zinovyev
arXiv (Cornell University)
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2 citations
2 citations
3095 days before retraction
Abundance, arrangement, and function of sequence motifs in the chicken promoters
Hideaki Abe, Neil J. Gemmell
BMC Genomics
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Published: Jan 2014
20 citations
20 citations
3095 days before retraction
Sarcomagenesis
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3095 days before retraction
Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer
Sven Bilke, Raphaela Schwentner, Fan Yang et al. (11 authors)
Genome Research
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107 citations
107 citations
3237 days before retraction
Quick Stats
Total Citations:
198
Years Since Retraction:
3.4 years
Open Access:
Yes
Last Checked:
Jul 24, 2025