Expression of concern
Schisandrin B Attenuates Cancer Invasion and Metastasis Via Inhibiting Epithelial-Mesenchymal Transition
Paper Information
Record ID:
39448
Author(s):
Publication Date:
July 25, 2012
Retraction Date:
September 29, 2022
(3.1 years years ago)
Subjects:
Institutions:
- Cancer Institute (Key Laboratory for Cancer Intervention and Prevention of China National Ministry of Education), The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
- Second Department of General Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Zhangjiang, People’s Republic of China
Country:
🇨🇳 ChinaArticle Type:
Publisher:
PLoS
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Expression of concern Details
Retraction Reasons:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1371/journal.pone.0275601Citations (65)
65
Total Citations12
Post-Retraction(18.5%)
52
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
0
Within 30 days
3
Within 1 year
4
After 2+ years
982
Days since retraction (latest)
Insights Into Anticancer Mechanisms of Schisandrin B: Isolation, Pharmacokinetics, and Preclinical Evidence
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Preclinical Concomitant Toxicokinetic Study of Schisandrin B by HPLC–MS/MS
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1 citation
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A comprehensive review of Schisandrin B’s preclinical antitumor activity and mechanistic insights from network pharmacology
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The promising antioxidant effects of lignans: Nrf2 activation comes into view
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10 citations
10 citations
581 days after retraction
Schisandrin B Suppresses Colon Cancer Growth by Inducing Cell Cycle Arrest and Apoptosis: Molecular Mechanism and Therapeutic Potential
Vanessa Anna Co, Hani El‐Nezami, Yawen Liu et al. (11 authors)
ACS Pharmacology & Translational Science
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8 citations
8 citations
511 days after retraction
The Use of Schisandrin B to Combat Triple-Negative Breast Cancers by Inhibiting NLRP3-Induced Interleukin-1β Production
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Biomolecules
Open Access
Published: Jan 2024
9 citations
9 citations
463 days after retraction
Schisandrin B Alleviates Renal Tubular Cell Epithelial–Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5′-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease
Weilin Liu, Fan Li, Dongwei Guo et al. (8 authors)
Molecules
Open Access
Published: Nov 2023
4 citations
4 citations
426 days after retraction
Inhibition of autophagy enhances the anticancer effect of Schisandrin B on head and neck squamous cell carcinoma
Mengmeng Li, Qinglai Tang, Shisheng Li et al. (8 authors)
Journal of Biochemical and Molecular Toxicology
Published: Nov 2023
4 citations
4 citations
417 days after retraction
Schisandrin B suppresses colon cancer growth by inducing cell cycle arrest and apoptosis via the CHOP signalling pathway
Vanessa Anna Co, Hani El‐Nezami, Yawen Liu et al. (11 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Aug 2023
332 days after retraction
A LC-MS/MS Method for Quantifying the Schisandrin B and Exploring Its Intracellular Exposure Correlating Antitumor Effect
Bosu Meng, Shouhong Gao, Jihui Chen et al. (8 authors)
Journal of Analytical Methods in Chemistry
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Published: Jun 2023
2 citations
2 citations
250 days after retraction
Schisandrin B inhibits cell growth and adherence in melanoma cancer cells
Unknown Authors
Unknown Journal
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Published: Jan 2023
94 days after retraction
Expression of Concern: Schisandrin B Attenuates Cancer Invasion and Metastasis Via Inhibiting Epithelial-Mesenchymal Transition
Unknown Authors
PLoS ONE
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Published: Sep 2022
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Schisandrin B exerts anticancer effects on human gastric cancer cells through ROS-mediated MAPK, STAT3, and NF-κB pathways
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Biocell
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2 citations
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30 days before retraction
Schisandrin B Induced ROS-Mediated Autophagy and Th1/Th2 Imbalance via Selenoproteins in Hepa1-6 Cells
Siran Tan, Z. Zheng, Tianqi Liu et al. (6 authors)
Frontiers in Immunology
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Published: Mar 2022
15 citations
15 citations
185 days before retraction
siRNA‐induced CD44 knockdown suppresses the proliferation and invasion of colorectal cancer stem cells through inhibiting epithelial–mesenchymal transition
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12 citations
12 citations
212 days before retraction
Regulation of cell signaling pathways by Schisandrin in different cancers: Opting for "Swiss Army Knife" instead of "Blunderbuss"
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Cellular and Molecular Biology
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5 citations
5 citations
365 days before retraction
Roles of Claspin in regulation of DNA replication, replication stress responses and oncogenesis in human cells
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Genome Instability & Disease
Open Access
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17 citations
17 citations
387 days before retraction
Schisandrin B inhibits epithelial‑mesenchymal transition and stemness of large‑cell lung cancer cells and tumorigenesis in xenografts via inhibiting the NF‑κB and p38 MAPK signaling pathways
Shuping Li, Hong Wang, Ruidong Ma et al. (4 authors)
Oncology Reports
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21 citations
21 citations
520 days before retraction
The influence of dibenzocyclooctadiene lignans on macrophage glutathione and lipid metabolism associated with Chlamydia pneumoniae-induced foam cell formation
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Advances in Redox Research
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4 citations
4 citations
555 days before retraction
Schisandrin B-mediated TH17 cell differentiation attenuates bowel inflammation
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Pharmacological Research
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20 citations
20 citations
603 days before retraction
Progress towards a clinically-successful ATR inhibitor for cancer therapy
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Current Research in Pharmacology and Drug Discovery
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104 citations
104 citations
636 days before retraction
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Cancers
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4 citations
4 citations
743 days before retraction
Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis
Xueni Wang, Xiuling Liao, Yimin Zhang et al. (5 authors)
Scientific Reports
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Published: Sep 2020
8 citations
8 citations
757 days before retraction
Enhanced antitumour efficacy of functionalized doxorubicin plus schisandrin B co-delivery liposomes via inhibiting epithelial-mesenchymal transition
Fu-Yi Cai, Xuemin Yao, Ming Jing et al. (11 authors)
Journal of Liposome Research
Published: Mar 2020
12 citations
12 citations
920 days before retraction
A Comprehensive Review on Schisandrin B and Its Biological Properties
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Oxidative Medicine and Cellular Longevity
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Published: Mar 2020
91 citations
91 citations
927 days before retraction
Potential Role of Biochemical Components of Schisandra chinensis for Prevention and Treatment of Obesity, Type 2 Diabetes Mellitus, Cancer and Prevention of Aging - A Systematic Review
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Acta Scientifci Nutritional Health
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Published: Jul 2019
1 citation
1 citation
1156 days before retraction
Potential of Schisandra chinensis (Turcz.) Baill. in Human Health and Nutrition: A Review of Current Knowledge and Therapeutic Perspectives
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102 citations
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1333 days before retraction
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17 citations
17 citations
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Recent Advances of Novel Therapeutic Agents from Botanicals for Prevention and Therapy of Breast Cancer: An Updated Review
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1400 days before retraction
Epithelial-mesenchymal transition as a target for botanicals in cancer metastasis
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24 citations
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1423 days before retraction
Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3
Xuanxuan Dai, Changtian Yin, Guilong Guo et al. (9 authors)
Toxicology and Applied Pharmacology
Published: Sep 2018
46 citations
46 citations
1485 days before retraction
Stereoisomers of Schisandrin B Are Potent ATP Competitive GSK-3β Inhibitors with Neuroprotective Effects against Alzheimer’s Disease: Stereochemistry and Biological Activity
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ACS Chemical Neuroscience
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32 citations
32 citations
1556 days before retraction
Seeking for Strategies to Support the Blood-Brain Barrier in the Protection Against Invading Cells
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Unknown Journal
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10 citations
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21 citations
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1724 days before retraction
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Factors involved in cancer metastasis: a better understanding to “seed and soil” hypothesis
Qiang Liu, Hongfei Zhang, Xiaoli Jiang et al. (6 authors)
Molecular Cancer
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283 citations
283 citations
1763 days before retraction
Schisandrin B reverses doxorubicin resistance through inhibiting P-glycoprotein and promoting proteasome-mediated degradation of survivin
Shengpeng Wang, Anqi Wang, Min Shao et al. (6 authors)
Scientific Reports
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Published: Aug 2017
33 citations
33 citations
1876 days before retraction
WITHDRAWN: The anti-growth and anti-metastasis effects of Schisandrin B on hepatocarcinoma cells in vitro and in vivo
Ruijie Sun, Ruiren Zhai, Changlin Ma et al. (4 authors)
Biochemical and Biophysical Research Communications
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2 citations
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1946 days before retraction
Evidence of drug-response heterogeneity rapidly generated from a single cancer cell
Rong Wang, Chengmeng Jin, Xun Hu
Oncotarget
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13 citations
13 citations
1996 days before retraction
Schisandrin B inhibits the proliferation and invasion of glioma cells by regulating the HOTAIR–micoRNA-125a–mTOR pathway
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32 citations
2115 days before retraction
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2 citations
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2189 days before retraction
Schisandrin B inhibits cell proliferation and induces apoptosis in human cholangiocarcinoma cells
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31 citations
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2249 days before retraction
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31 citations
2381 days before retraction
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66 citations
66 citations
2484 days before retraction
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25 citations
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2505 days before retraction
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17 citations
17 citations
2568 days before retraction
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Unknown Journal
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2591 days before retraction
Quick Stats
Total Citations:
65
Years Since Retraction:
3.1 years
Open Access:
Yes
Last Checked:
Jul 24, 2025