Retraction

Isoquercitrin inhibits the progression of liver cancer in vivo and in vitro via the MAPK signalling pathway

Paper Information

Record ID:

42993

Author(s):

Guihong Huang
Bo Tang
Kun Tang
Xiaomin Dong
Jungang Deng
Luqin Liao
Zengzhen Liao
Hua Yang
Songqing He

Journal:

Oncology Reports ( Spandidos )

Publication Date:

March 20, 2014

Retraction Date:

February 28, 2023 (2.7 years years ago)

Subjects:

Broad Categories:
Biology Biochemistry Toxicology

Specific Fields:
Biochemistry Biology - Cancer Toxicology

Institutions:

Country:

🇨🇳 China

Article Type:

Research Article

Publisher:

Spandidos

Open Access:

Yes

DOI:

10.3892/or.2014.3099

PubMed ID:

24676882

Retraction PubMed ID:

36866771

Retraction Details

Retraction Reasons:

Nature of Retraction:

Retraction

Retraction Notice:

10.3892/or.2023.8510

Additional Notes:

see also: https://pubpeer.com/publications/5BD3CC562EE97C12ECECF4CE0572EE

Citations (64)

64

Total Citations

9

Post-Retraction
(14.1%)

54

Pre-Retraction

1

Same Day

Post-Retraction Citation Analysis

0 Within 30 days

7 Within 1 year

1 After 2+ years

843 Days since retraction (latest)

Therapeutic Potential and Molecular Mechanisms of Natural Flavonoids in Liver Cancer

Rohit Tripathi, Abhay Kumar Yadav, Avadh Biharee et al. (8 authors)

Pharmacological Research - Natural Products

Published: Jun 2025

843 days after retraction

Paper citing Isoquercitrin inhibits the progression of liver ca...

Unknown Authors

Unknown Journal

Published: Feb 2025

704 days after retraction

Silencing HDAC1 Expression Regulates Extracellular Regulated Protein Kinases/Mitogen-Activated Protein Kinase Signaling Activation and Enhances Chemosensitivity of Ovarian Carcinoma

Jia Xu, Yan Li, Hai‐Xu Wang et al. (7 authors)

Journal of Biomedical Nanotechnology

Published: Jan 2024

307 days after retraction

A Network Pharmacology and Molecular-Docking-Based Approach to Identify the Probable Targets of Short-Chain Fatty-Acid-Producing Microbial Metabolites against Kidney Cancer and Inflammation

Md Rezaul Karim, Md. Niaj Morshed, Safia Iqbal et al. (9 authors)

Biomolecules Open Access

Published: Nov 2023
10 citations

265 days after retraction

Total Flavonoids in Artemisia absinthium L. and Evaluation of Its Anticancer Activity

Meizhu He, Kamarya Yasin, Shaoqi Yu et al. (5 authors)

International Journal of Molecular Sciences Open Access

Published: Nov 2023
13 citations

260 days after retraction

A potential Chinese medicine monomer against influenza A virus and influenza B virus: isoquercitrin

Rongbo Luo, Chaoxiang Lv, Tiecheng Wang et al. (12 authors)

Chinese Medicine Open Access

Published: Nov 2023
8 citations

247 days after retraction

Exploring the therapeutic potential of natural compounds for Alzheimer's disease: Mechanisms of action and pharmacological properties

Jinman Liu, Tianyao Li, Guangcheng Zhong et al. (11 authors)

Biomedicine & Pharmacotherapy Open Access

Published: Sep 2023
18 citations

188 days after retraction

Total flavonoids in Artemisia absinthium L. and evaluation of its anticancer activity

Meizhu He, Kamarya Yasin, Zihang Ma et al. (5 authors)

Research Square (Research Square) Open Access

Published: Jun 2023
7 citations

118 days after retraction

Antiangiogenic, Anti-Inflammatory and Antioxidant Properties of Bidens tripartite Herb, Galium verum Herb and Rumex hydrolapathum Root

Katarzyna Antoniak, Elżbieta Studzińska-Sroka, Marcin Szymański et al. (6 authors)

Molecules Open Access

Published: Jun 2023
15 citations

116 days after retraction

Role of Plant-Derived Compounds in the Molecular Pathways Related to Inflammation

Agata J. Olędzka, Monika E. Czerwińska

International Journal of Molecular Sciences Open Access

Published: Feb 2023
15 citations

Same day as retraction

Apoptotic Mechanisms of Quercetin in Liver Cancer: Recent Trends and Advancements

Gautam Sethi, Prangya Rath, Abhishek Chauhan et al. (10 authors)

Pharmaceutics Open Access

Published: Feb 2023
74 citations

8 days before retraction

Isoquercitrin restrains the proliferation and promotes apoptosis of human osteosarcoma cells by inhibiting the Wnt/β-catenin pathway

Zhun Wei, Di Zheng, Wenfeng Pi et al. (6 authors)

Journal of bone oncology Open Access

Published: Jan 2023
10 citations

56 days before retraction

miR-135a inhibits the proliferation of HBV-infected hepatocellular carcinoma cells by targeting HOXA10

Jianjun Lin, Xiang Lian, Shihang Xue et al. (7 authors)

Translational Cancer Research Open Access

Published: Jan 2023
5 citations

58 days before retraction

Anticancer potential of phytochemicals from Oroxylum indicum targeting Lactate Dehydrogenase A through bioinformatic approach

Sheikh Sunzid Ahmed, M Oliur Rahman, Ali S. Alqahtani et al. (7 authors)

Toxicology Reports Open Access

Published: Dec 2022
24 citations

76 days before retraction

Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets

Parina Asgharian, Abbas Pirpour Tazekand, Kamran Hosseini et al. (15 authors)

Cancer Cell International Open Access

Published: Aug 2022
168 citations

197 days before retraction

Possible ameliorating effect of isoquercetin on diethylnitrosamine-induced hepatocellular carcinoma in albino mice

Kholoud A. Omran, Yomna I. Mahmoud, Asmaa Mahmoud et al. (4 authors)

Egyptian Journal of Basic and Applied Sciences Open Access

Published: Jun 2022

259 days before retraction

Combined Metabolome and Transcriptome Analyses Reveal the Flavonoids Changes and Biosynthesis Mechanisms in Different Organs of Hibiseu manihot L.

Yuhan Zhou, Xiaodi Xu, Yanzhu Chen et al. (7 authors)

Frontiers in Plant Science Open Access

Published: Mar 2022
19 citations

350 days before retraction

Plant molecules and their influence on health and female reproduction

Alexander V. Sirotkin, Adriana Kolesárová

Elsevier eBooks

Published: Jan 2022
8 citations

423 days before retraction

Isoquercitrin Upregulates Aldolase C Through Nrf2 to Ameliorate OGD/R-Induced Damage in SH-SY5Y Cells

Shichang Cai, Chuan-an Yi, Xiang-Shang Hu et al. (6 authors)

Neurotoxicity Research

Published: Nov 2021
9 citations

472 days before retraction

Antioxidative Effect of Dietary Flavonoid Isoquercitrin on Human Ovarian Granulosa Cells HGL5 In Vitro

Adriana Kolesárová, Katarína Michalcová, Shubhadeep Roychoudhury et al. (9 authors)

Physiological Research Open Access

Published: Oct 2021
8 citations

485 days before retraction

Anticancer Effects of the Corchorus olitorius Aqueous Extract and Its Bioactive Compounds on Human Cancer Cell Lines

John Paul Sese Tosoc, Olga M. Nuñeza, Thangirala Sudha et al. (5 authors)

Molecules Open Access

Published: Oct 2021
16 citations

511 days before retraction

Polyphenols from Broussonetia papyrifera Induce Apoptosis of HepG2 Cells via Inactivation of ERK and AKT Signaling Pathways

Dou Chenzhuo, Yanfen Liu, Lulu Zhang et al. (7 authors)

Evidence-based Complementary and Alternative Medicine Open Access

Published: Mar 2021
9 citations

707 days before retraction

PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression

Jayaprakash Mandal, Chiou-Nan Shiue, Yen-Cheng Chen et al. (11 authors)

Free Radical Biology and Medicine Open Access

Published: Dec 2020
44 citations

812 days before retraction

Evaluation of the In Vitro and In Vivo Antitumor Efficacy of Peanut Sprout Extracts Cultivated with Fermented Sawdust Medium Against Bladder Cancer

Hongbeom Park, Junhui Song, Byung‐Doo Hwang et al. (7 authors)

Applied Sciences Open Access

Published: Dec 2020
4 citations

813 days before retraction

Isoquercitrin induces apoptosis and autophagy in hepatocellular carcinoma cells via AMPK/mTOR/p70S6K signaling pathway

Liyan Shui, Weina Wang, Mingjie Xie et al. (7 authors)

Aging Open Access

Published: Nov 2020
65 citations

821 days before retraction

Cytotoxic activity of butanolic extract from Sambucus nigra L. flowers in natura and vehiculated in micelles in bladder cancer cells and fibroblasts

Deise Inocêncio Pereira, Tatiane Roquete Amparo, Tamires Cunha Almeida et al. (8 authors)

Natural Product Research Open Access

Published: Nov 2020
14 citations

825 days before retraction

Antitumor potential of Hedyotis diffusa Willd: A systematic review of bioactive constituents and underlying molecular mechanisms

Xinru Han, Xiang Zhang, Qian Wang et al. (5 authors)

Biomedicine & Pharmacotherapy Open Access

Published: Sep 2020
38 citations

899 days before retraction

Cellular target of isoquercetin from Passiflora ligularis Juss for glucose uptake in rat soleus muscle

Diana Rey, Thaís Alves Fernandes, Paola Miranda Sulis et al. (10 authors)

Chemico-Biological Interactions

Published: Jul 2020
21 citations

955 days before retraction

Effect of Malus asiatica Nakai Leaf Flavonoids on the Prevention of Esophageal Cancer in C57BL/6J Mice by Regulating the IL-17 Signaling Pathway

Xiangbo Jia, Quan Zhang, Lei Xu et al. (5 authors)

OncoTargets and Therapy Open Access

Published: Jul 2020
15 citations

972 days before retraction

STAT3 Inhibition by Centipede Scolopendra Extract in Liver Cancer HepG2 Cells and Orthotopic Mouse Models of Hepatocellular Carcinoma

Teng Yong-Jiea, Liu Zhuob, Liao Liuc et al. (6 authors)

Digital Chinese Medicine Open Access

Published: Jun 2020
1 citation

1002 days before retraction

Hydrazinocurcumin Induces Apoptosis of Hepatocellular Carcinoma Cells Through the p38 MAPK Pathway

Hongtao He, Kuangyuan Qiao, Chao Wang et al. (9 authors)

Clinical and Translational Science Open Access

Published: Feb 2020
13 citations

1098 days before retraction

Identification and characterization of health-promoting benefits and bioactive molecules in black walnuts (Juglans nigra l.) and waste materials from agroforestry systems

Van Khanh Ho

Unknown Journal Open Access

Published: Jan 2020

1154 days before retraction

Inhibitory Effect of Nelumbo nucifera Leaf Extract on 2-Acetylaminofluorene-induced Hepatocarcinogenesis Through Enhancing Antioxidative Potential and Alleviating Inflammation in Rats

Mon‐Yuan Yang, Tung‐Wei Hung, Chau‐Jong Wang et al. (4 authors)

Antioxidants Open Access

Published: Aug 2019
17 citations

1286 days before retraction

In vitro response of human ovarian cancer cells to dietary bioflavonoid isoquercitrin

Katarína Michalcová, Shubhadeep Roychoudhury, Marek Halenár et al. (11 authors)

Journal of Environmental Science and Health Part B

Published: Jul 2019
16 citations

1335 days before retraction

Jinmaitong, a Traditional Chinese Compound Prescription, Ameliorates the Streptozocin-Induced Diabetic Peripheral Neuropathy Rats by Increasing Sciatic Nerve IGF-1 and IGF-1R Expression

Wei Song, Wen Jiang, Chao Wang et al. (9 authors)

Frontiers in Pharmacology Open Access

Published: Mar 2019
28 citations

1432 days before retraction

The Increase of ROS Caused by the Interference of DEHP with JNK/p38/p53 Pathway as the Reason for Hepatotoxicity

Yuanyuan Huang, Chuancheng Wu, Youbin Ye et al. (12 authors)

International Journal of Environmental Research and Public Health Open Access

Published: Jan 2019
58 citations

1493 days before retraction

Acer okamotoanumand isoquercitrin improve cognitive functionviaattenuation of oxidative stress in high fat diet- and amyloid beta-induced mice

Ji Hyun Kim, Sanghyun Lee, Eun Ju Cho

Food & Function

Published: Jan 2019
29 citations

1519 days before retraction

What Chinese Medicine Can Do for Liver Cancer?

Feiyu Chen, Ning Wang, Yibin Feng

Liver Cancer Open Access

Published: Nov 2018
1 citation

1560 days before retraction

Isoquercitrin Attenuated Cardiac Dysfunction Via AMPKα‐Dependent Pathways in LPS‐Treated Mice

Sihui Huang, Man Xu, Hai‐Ming Wu et al. (9 authors)

Molecular Nutrition & Food Research

Published: Oct 2018
52 citations

1587 days before retraction

Hint1 expression inhibits proliferation and promotes radiosensitivity of human SGC7901 gastric cancer cells

Xiaowei Wei, Jin Zhou, Lingzhi Hong et al. (7 authors)

Oncology Letters Open Access

Published: Jun 2018
10 citations

1729 days before retraction

Isoquercitrin, ingredients in Tetrastigma hemsleyanum Diels et Gilg, inhibits hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion

Gengshou Xia, Shuhong Li, Wu Zhou

Cell Adhesion & Migration Open Access

Published: May 2018
15 citations

1756 days before retraction

The Potential and Action Mechanism of Polyphenols in the Treatment of Liver Diseases

Sha Li, Hor‐Yue Tan, Ning Wang et al. (6 authors)

Oxidative Medicine and Cellular Longevity Open Access

Published: Jan 2018
170 citations

1884 days before retraction

TECHNOLOGY DEVELOPMENT AND STANDARDIZATION OF HEATHER SHOOTS TINCTURE

О. А. Веремчук, Д. В. Моисеев

Belgorod State University Scientific bulletin Medicine Pharmacy Open Access

Published: Jan 2018
1 citation

1884 days before retraction

Hepatoprotective potential of isoquercitrin against type 2 diabetes-induced hepatic injury in rats

Xiaoli Huang, Yang He, Lili Ji et al. (9 authors)

Oncotarget Open Access

Published: Sep 2017
51 citations

1991 days before retraction

3-O-Glucosylation of quercetin enhances inhibitory effects on the adipocyte differentiation and lipogenesis

Chang Won Lee, Jeong Yeon Seo, Jisun Lee et al. (10 authors)

Biomedicine & Pharmacotherapy

Published: Sep 2017
44 citations

2004 days before retraction

Assessing the anticancer effects associated with food products and/or nutraceuticals using in vitro and in vivo preclinical development-related pharmacological tests

Florence Lefranc, Nurhayat Tabanca, Róbert Kiss

Seminars in Cancer Biology Open Access

Published: Jun 2017
25 citations

2092 days before retraction

Pentoxifylline induces apoptosis of HepG2 cells by reducing reactive oxygen species production and activating the MAPK signaling

Yan Wang, Lei Dong, Jing Li et al. (5 authors)

Life Sciences

Published: Jun 2017
16 citations

2096 days before retraction

Dynamic changes of flavonoids in Abelmoschus manihot different organs at different growth periods by UPLC–MS/MS

Xinxin Pan, Leyue Du, Jinhua Tao et al. (6 authors)

Journal of Chromatography B

Published: May 2017
35 citations

2107 days before retraction

NOR1 promotes hepatocellular carcinoma cell proliferation and migration through modulating the Notch signaling pathway

Kun You, Peisheng Sun, Zhongyi Yue et al. (6 authors)

Experimental Cell Research

Published: Feb 2017
17 citations

2197 days before retraction

Natural Compounds as Modulators of Cell Cycle Arrest: Application for Anticancer Chemotherapies

Natalia Bailón-Moscoso, Gabriela Cevallos-Solorzano, Juan Carlos Romero-Benavides et al. (4 authors)

Current Genomics Open Access

Published: Jan 2017
143 citations

2220 days before retraction

Quick Stats

Total Citations: 64

Years Since Retraction: 2.7 years

Open Access: Yes

Last Checked: Jul 24, 2025

Actions

More from this journal Similar subjects View Original Paper View Retraction Notice