Retraction
Increased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21
Paper Information
Record ID:
43115
Author(s):
Publication Date:
December 02, 2013
Retraction Date:
February 27, 2023
(2.7 years years ago)
Subjects:
Institutions:
Country:
🇺🇸 United StatesArticle Type:
Publisher:
Wiley
Open Access:
Yes
DOI:
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (97)
97
Total Citations6
Post-Retraction(6.2%)
91
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
2
Within 1 year
0
After 2+ years
637
Days since retraction (latest)
Assessing Association Between Circulating Bilirubin Levels and the Risk of Frailty: An Observational and Mendelian Randomization Study
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Journal of Cachexia Sarcopenia and Muscle
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637 days after retraction
Bilirubin metabolism and its disorders
Namita Roy‐Chowdhury, Patrik Asp, Chandan Guha et al. (4 authors)
Elsevier eBooks
Published: Nov 2024
634 days after retraction
Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology
Francesca Maria Consonni, Martina Incerti, Milena Bertolotti et al. (6 authors)
Frontiers in Immunology
Open Access
Published: Oct 2024
3 citations
3 citations
605 days after retraction
Retraction Note: PPARδ binding to heme oxygenase 1 promoter prevents angiotensin II-induced adipocyte dysfunction in Goldblatt hypertensive rats
Komal Sodhi, Nitin Puri, Dong Hyun Kim et al. (10 authors)
International Journal of Obesity
Published: Jul 2024
505 days after retraction
دراسة دور الهيم اوكسجينيز-1 في المرضى الذين يعانون من السمنة
Nabaa Adnan Mohammed, Fayhaa M. Khaleel
Baghdad Science Journal
Open Access
Published: Dec 2023
3 citations
3 citations
300 days after retraction
An Assessment of Heme Oxygenase-1 and Glutathione-S-transferase in Obese Iraqi Patients
Nabaa Adnan Mohammed, Fayhaa M. Khaleel
Baghdad Science Journal
Open Access
Published: Nov 2023
1 citation
1 citation
265 days after retraction
Suppressing Hepatic UGT1A1 Increases Plasma Bilirubin, Lowers Plasma Urobilin, Reorganizes Kinase Signaling Pathways and Lipid Species and Improves Fatty Liver Disease
Evelyn Bates, Zachary A. Kipp, Genesee J. Martinez et al. (12 authors)
Biomolecules
Open Access
Published: Jan 2023
17 citations
17 citations
29 days before retraction
Powering the powerhouse: Heme oxygenase‐1 regulates mitochondrial function in non‐alcoholic fatty liver disease (NAFLD)
Terry D. Hinds, David E. Stec, Claudio Tiribelli
Acta Physiologica
Open Access
Published: Jan 2023
5 citations
5 citations
49 days before retraction
Genome Editing and Fatty Liver
Umar Hayat, Ali A. Siddiqui, Muhammad Farhan et al. (5 authors)
Advances in experimental medicine and biology
Published: Dec 2022
1 citation
1 citation
88 days before retraction
The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease
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Metabolites
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4 citations
4 citations
130 days before retraction
Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity
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International Journal of Molecular Sciences
Open Access
Published: Sep 2022
1 citation
1 citation
166 days before retraction
Peroxisome Proliferator-Activated Receptor α Has a Protective Effect on Fatty Liver Caused by Excessive Sucrose Intake
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Published: Sep 2022
7 citations
7 citations
174 days before retraction
The hypolipidemic, anti-inflammatory and antioxidant effect of Kavolì® aqueous extract, a mixture of Brassica oleracea leaves, in a rat model of NAFLD
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Food and Chemical Toxicology
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7 citations
7 citations
239 days before retraction
Adipocyte-Specific Expression of PGC1α Promotes Adipocyte Browning and Alleviates Obesity-Induced Metabolic Dysfunction in an HO-1-Dependent Fashion
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Antioxidants
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Published: Jun 2022
27 citations
27 citations
262 days before retraction
Hepatic kinome atlas: An in‐depth identification of kinase pathways in liver fibrosis of humans and rodents
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Hepatology
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Published: Mar 2022
41 citations
41 citations
343 days before retraction
Adipose-Specific PPARα Knockout Mice Have Increased Lipogenesis by PASK–SREBP1 Signaling and a Polarity Shift to Inflammatory Macrophages in White Adipose Tissue
Terry D. Hinds, Zachary A. Kipp, Mei Xu et al. (8 authors)
Cells
Open Access
Published: Dec 2021
55 citations
55 citations
433 days before retraction
Association of Serum Bilirubin and Functional Variants of Heme Oxygenase 1 and Bilirubin UDP-Glucuronosyl Transferase Genes in Czech Adult Patients with Non-Alcoholic Fatty Liver Disease
J Petrtýl, Karel Dvořák, J Stŕíteský et al. (9 authors)
Antioxidants
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Published: Dec 2021
11 citations
11 citations
439 days before retraction
Retraction: Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet
Unknown Authors
PLoS ONE
Open Access
Published: Nov 2021
480 days before retraction
Bilirubin represents a negative regulator of ILC2 in allergic airway inflammation
Juan He, Guanmin Jiang, Xing Li et al. (14 authors)
Mucosal Immunology
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Published: Oct 2021
15 citations
15 citations
493 days before retraction
Biliverdin reductase-A protein levels are reduced in type 2 diabetes and are associated with poor glycometabolic control
Flavia Agata Cimini, Ilaria Barchetta, Ilaria Zuliani et al. (11 authors)
Life Sciences
Published: Aug 2021
10 citations
10 citations
551 days before retraction
Identification of Binding Regions of Bilirubin in the Ligand-Binding Pocket of the Peroxisome Proliferator-Activated Receptor-A (PPARalpha)
Darren M. Gordon, Stephen Hong, Zachary A. Kipp et al. (4 authors)
Molecules
Open Access
Published: May 2021
39 citations
39 citations
651 days before retraction
The Protective Role of the Heme Catabolic Pathway in Hepatic Disorders
Libor Vı́tek
Antioxidants and Redox Signaling
Published: Apr 2021
5 citations
5 citations
670 days before retraction
Skeletal muscle heme oxygenase-1 activity regulates aerobic capacity
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Cell Reports
Open Access
Published: Apr 2021
26 citations
26 citations
697 days before retraction
Milk Fat Globule Membrane Supplementation During Suckling Ameliorates Maternal High Fat Diet–Induced Hepatic Steatosis in Adult Male Offspring of Mice
Qianren Zhang, Lin Ye, Feng‐Zhi Xin et al. (7 authors)
Journal of Nutrition
Open Access
Published: Feb 2021
8 citations
8 citations
732 days before retraction
Bilirubin: A Ligand of the PPARα Nuclear Receptor
Stephen Hong, Darren M. Gordon, David E. Stec et al. (4 authors)
Springer eBooks
Published: Jan 2021
4 citations
4 citations
787 days before retraction
Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate
Terry D. Hinds, Justin F. Creeden, Darren M. Gordon et al. (6 authors)
Frontiers in Pharmacology
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Published: Dec 2020
74 citations
74 citations
801 days before retraction
Natural Product Heme Oxygenase Inducers as Treatment for Nonalcoholic Fatty Liver Disease
David E. Stec, Terry D. Hinds
International Journal of Molecular Sciences
Open Access
Published: Dec 2020
45 citations
45 citations
805 days before retraction
Gasotransmitter signaling in energy homeostasis and metabolic disorders
Amr Ali, Yuehong Wang, Lingyun Wu et al. (4 authors)
Free Radical Research
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23 citations
23 citations
809 days before retraction
Bilirubin as a metabolic hormone: the physiological relevance of low levels
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AJP Endocrinology and Metabolism
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Published: Dec 2020
170 citations
170 citations
812 days before retraction
Modeling Non-Alcoholic Fatty Liver Disease (NAFLD) Using “Good-Fit” Genome-Editing Tools
Uijin Kim, Nahyun Kim, Ha Youn Shin
Cells
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Published: Dec 2020
7 citations
7 citations
818 days before retraction
Rats Genetically Selected for High Aerobic Exercise Capacity Have Elevated Plasma Bilirubin by Upregulation of Hepatic Biliverdin Reductase-A (BVRA) and Suppression of UGT1A1
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Antioxidants
Open Access
Published: Sep 2020
29 citations
29 citations
891 days before retraction
Predicting Nonalcoholic Fatty Liver Disease through a Panel of Plasma Biomarkers and MicroRNAs in Female West Virginia Population
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International Journal of Molecular Sciences
Open Access
Published: Sep 2020
26 citations
26 citations
897 days before retraction
Therapeutic application and construction of bilirubin incorporated nanoparticles
Qing Yao, Ruijie Chen, Vadivel Ganapathy et al. (4 authors)
Journal of Controlled Release
Published: Sep 2020
51 citations
51 citations
909 days before retraction
Cold Press Pomegranate Seed Oil Attenuates Dietary-Obesity Induced Hepatic Steatosis and Fibrosis through Antioxidant and Mitochondrial Pathways in Obese Mice
Marco Raffaele, Maria Licari, Sherif Amin et al. (12 authors)
International Journal of Molecular Sciences
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Published: Jul 2020
37 citations
37 citations
941 days before retraction
GSK-3 in liver diseases: Friend or foe?
Maria Rita Emma, Giuseppa Augello, Antonella Cusimano et al. (7 authors)
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Open Access
Published: May 2020
19 citations
19 citations
1018 days before retraction
Bilirubin remodels murine white adipose tissue by reshaping mitochondrial activity and the coregulator profile of peroxisome proliferator–activated receptor α
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Journal of Biological Chemistry
Open Access
Published: May 2020
80 citations
80 citations
1019 days before retraction
Therapeutic approaches to diabetic cardiomyopathy: Targeting the antioxidant pathway
Michael Arad, Maayan Waldman, Nader G. Abraham et al. (4 authors)
Prostaglandins & Other Lipid Mediators
Published: May 2020
15 citations
15 citations
1020 days before retraction
Biliverdin Reductase A (BVRA) Knockout in Adipocytes Induces Hypertrophy and Reduces Mitochondria in White Fat of Obese Mice
David E. Stec, Darren M. Gordon, Andrea L. Nestor‐Kalinoski et al. (7 authors)
Biomolecules
Open Access
Published: Mar 2020
42 citations
42 citations
1092 days before retraction
Bilirubin as a signaling molecule
Libor Vı́tek
Medicinal Research Reviews
Published: Feb 2020
110 citations
110 citations
1119 days before retraction
Disorders of Bilirubin Metabolism
Namita Roy Chowdhury, Yanfeng Li, Jayanta Roy Chowdhury
Unknown Journal
Published: Jan 2020
4 citations
4 citations
1130 days before retraction
Heme Oxygenase-1 Upregulation: A Novel Approach in the Treatment of Cardiovascular Disease
Lars Bellner, Nachum B. Lebovics, Rochelle Rubinstein et al. (9 authors)
Antioxidants and Redox Signaling
Open Access
Published: Dec 2019
27 citations
27 citations
1154 days before retraction
The Effects of Heme Oxygenase Upregulation on Obesity and the Metabolic Syndrome
Stephen J. Peterson, Niel Dave, Janish Kothari
Antioxidants and Redox Signaling
Published: Dec 2019
14 citations
14 citations
1158 days before retraction
Bilirubin Safeguards Cardiorenal and Metabolic Diseases: a Protective Role in Health
Terry D. Hinds, David E. Stec
Current Hypertension Reports
Open Access
Published: Oct 2019
56 citations
56 citations
1236 days before retraction
Bilirubin reduces visceral obesity and insulin resistance by suppression of inflammatory cytokines
Ryoko Takei, Tomoaki Inoue, Noriyuki Sonoda et al. (8 authors)
PLoS ONE
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Published: Oct 2019
67 citations
67 citations
1244 days before retraction
Bile Pigment Metabolism and Its Disorders
Namita Roy‐Chowdhury, Wang Xia, Jayanta Roy‐Chowdhury
Elsevier eBooks
Published: Sep 2019
7 citations
7 citations
1270 days before retraction
Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity
David E. Stec, Darren M. Gordon, Jennifer Hipp et al. (10 authors)
AJP Regulatory Integrative and Comparative Physiology
Open Access
Published: Sep 2019
89 citations
89 citations
1272 days before retraction
HO-1 overexpression and underexpression: Clinical implications
George S. Drummond, Jeffrey Baum, Menachem Greenberg et al. (5 authors)
Archives of Biochemistry and Biophysics
Open Access
Published: Aug 2019
125 citations
125 citations
1291 days before retraction
CRISPR Cas9-mediated deletion of biliverdin reductase A (BVRA) in mouse liver cells induces oxidative stress and lipid accumulation
Darren M. Gordon, Samuel O. Adeosun, Somtochukwu I. Ngwudike et al. (7 authors)
Archives of Biochemistry and Biophysics
Open Access
Published: Aug 2019
35 citations
35 citations
1292 days before retraction
Inhibition of Heme Oxygenase Antioxidant Activity Exacerbates Hepatic Steatosis and Fibrosis In Vitro
Marco Raffaele, Giuseppe Carota, Giuseppe Sferrazzo et al. (8 authors)
Antioxidants
Open Access
Published: Aug 2019
22 citations
22 citations
1302 days before retraction
The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases
Yoshimi Kishimoto, Kazuo Kondo, Yukihiko Momiyama
International Journal of Molecular Sciences
Open Access
Published: Jul 2019
94 citations
94 citations
1314 days before retraction
Quick Stats
Total Citations:
97
Years Since Retraction:
2.7 years
Open Access:
Yes
Last Checked:
Jul 24, 2025