Retraction

Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis‑diammined dichloridoplatium

Paper Information

Record ID:
43620
Author(s):
Bo Tang
Jian Du
Jingwen Wang
Guang Tan
Zhenming Gao
Zhongyu Wang
Liming Wang
Journal:
Oncology Reports ( Spandidos )
Publication Date:
December 06, 2011
Retraction Date:
March 31, 2023 (2.6 years years ago)
Subjects:
Broad Categories:
Biology Toxicology
Institutions:
Country:
🇨🇳 China
Article Type:
Research Article
Publisher:
Spandidos
Open Access:
Yes
DOI:
10.3892/or.2011.1580
PubMed ID:
22159816
Retraction PubMed ID:
36999612

Retraction Details

Retraction Reasons:
Nature of Retraction:

Retraction

Retraction Notice:
10.3892/or.2023.8534
Additional Notes:

see also: https://pubpeer.com/publications/F7A3108839234381F135D9C6F417DB

Citations (41)

41
Total Citations
5
Post-Retraction
(12.2%)
36
Pre-Retraction
0
Same Day
Post-Retraction Citation Analysis
0 Within 30 days
3 Within 1 year
0 After 2+ years
493 Days since retraction (latest)
Conserved gatekeeper methionine regulates the binding and access of kinase inhibitors to ATP sites of MAP2K1, 4, and 7: Clues for developing selective inhibitors
Seigo Yumura, Daisuke Kitagawa, Kei Moritsugu et al. (7 authors)
Bioorganic & Medicinal Chemistry Letters
Published: Aug 2024
2 citations
493 days after retraction
LncRNA PCED1B-AS1 mediates miR-3681-3p/MAP2K7 axis to promote metastasis, invasion and EMT in gastric cancer
Jia Cao, Yicheng Yang, Bensong Duan et al. (7 authors)
Biology Direct Open Access
Published: May 2024
8 citations
398 days after retraction
Conserved Gatekeeper Methionine Regulates the Binding and Access of Kinase Inhibitors to Atp Sites of Map2k1, 4, and 7: Clues for Developing Selective Inhibitors
Seigo Yumura, Daisuke Kitagawa, Kei Moritsugu et al. (7 authors)
Unknown Journal
Published: Jan 2024
276 days after retraction
Active compounds of Caodoukou () inhibit the migration, invasion and metastasis of human pancreatic cancer cells by targeting phosphoinosmde-3-kinase/ protein kinase B/mammalian target of rapamycin pathway.
Xiaohui Yang, Jian Wang, Li Cheng et al. (6 authors)
PubMed
Published: Oct 2023
184 days after retraction
AB1532 ULTRASOUND ASSESSMENT OF A1 AND A2 PULLEY ENTHESIS WITH ANATOMICAL AND HISTOLOGICAL CORRELATION
Luis Coronel, Maribel Miguel, Juan Blasi et al. (6 authors)
Annals of the Rheumatic Diseases Open Access
Published: May 2023
60 days after retraction
Network analysis and basic experiments on the inhibition of renal cancer proliferation and migration by alpinetin through PI3K/AKT/mTOR pathway
Yu Guo, Lizhu Jiang, Shengjun Luo et al. (7 authors)
Research Square (Research Square) Open Access
Published: Jul 2022
256 days before retraction
Alpinetin: a Dietary Flavonoid with Diverse Anticancer Effects
Sameena Gul, Muhammad Faisal Maqbool, Dongying Zheng et al. (6 authors)
Applied Biochemistry and Biotechnology
Published: May 2022
12 citations
321 days before retraction
Exploration of Pharmacological Potential of Alpinetin
Randhir Singh, Dhirendra Singh
Current Nutrition & Food Science
Published: May 2022
322 days before retraction
Alpinetin: A Review of Its Pharmacology and Pharmacokinetics
Ge Zhao, Yue Tong, Fei Luan et al. (8 authors)
Frontiers in Pharmacology Open Access
Published: Feb 2022
34 citations
420 days before retraction
Differential effects of cisplatin combined with the flavonoid apigenin on HepG2, Hep3B, and Huh7 liver cancer cell lines
Fotini Papachristou, Nikolia Αnninou, Georgios Koukoulis et al. (9 authors)
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Published: Mar 2021
20 citations
737 days before retraction
Anti-Inflammatory Potential Exhibited by <i>Amomum subulatum</i> Fruits Mitigates Experimentally Induced Acute and Chronic Inflammation in Mice: Evaluation of Antioxidant Parameters, Pro-Inflammatory Mediators and HO-1 Pathway
Sudarsanan Drishya, Suresh Sulekha Dhanisha, Chandrashekharan Guruvayoorappan
Journal of the American College of Nutrition
Published: Jan 2021
7 citations
815 days before retraction
Alpinetin prevents inflammatory responses in OVA-induced allergic asthma through modulating PI3K/AKT/NF-κB and HO-1 signaling pathways in mice
Di Wu, Shuangqiu Li, Xiao Liu et al. (12 authors)
International Immunopharmacology
Published: Oct 2020
39 citations
904 days before retraction
The role of medicinal products in the treatment of inflammatory bowel diseases (<scp>IBD</scp>) through inhibition of <scp>TLR4</scp>/<scp>NF‐kappaB</scp> pathway
Pegah Dejban, Nasrin Nikravangolsefid, Mohsen Chamanara et al. (5 authors)
Phytotherapy Research
Published: Sep 2020
78 citations
928 days before retraction
Structural basis for producing selective MAP2K7 inhibitors
Yuka Murakawa, S. M. P. VALTER, Haim Barr et al. (5 authors)
Bioorganic & Medicinal Chemistry Letters
Published: Sep 2020
5 citations
930 days before retraction
Alpinetin Protects Chondrocytes and Exhibits Anti-Inflammatory Effects via the NF-κB/ERK Pathway for Alleviating Osteoarthritis
Yan Gao, Sixiang Wang, Long He et al. (5 authors)
Inflammation
Published: May 2020
29 citations
1034 days before retraction
Potential Pharmacotherapeutic Phytochemicals from Zingiberaceae for Cancer Prevention
Indrani Manna, Debalina Das, Sejuty Mondal et al. (4 authors)
Springer eBooks
Published: Jan 2020
4 citations
1185 days before retraction
Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products
Dongdong Wang, Yang Yang, Yingnan Lei et al. (8 authors)
Pharmacological Reviews Open Access
Published: Sep 2019
182 citations
1283 days before retraction
Alpinetin Inhibits Oral Squamous Cell Carcinoma Proliferation via miR-211-5p Upregulation and Notch Pathway Deactivation
Yanjun Guo, Yong Chen, Hongli Liu et al. (4 authors)
Nutrition and Cancer
Published: Aug 2019
17 citations
1327 days before retraction
Nano-engineered flavonoids for cancer protection
Pradyumna Kumar Mishra
Frontiers in bioscience
Published: Jan 2019
28 citations
1550 days before retraction
Alpinetin inhibits proliferation and migration of ovarian cancer cells via suppression of STAT3 signaling
Xuezhi Zhao, Xiaohan Guo, Junhua Shen et al. (4 authors)
Molecular Medicine Reports Open Access
Published: Aug 2018
41 citations
1682 days before retraction
A sensitive resonance Rayleigh light scattering method for alpinetin using gold nanorods probes
Shuyun Bi, Xiaoyue Sun, Yu Wang et al. (5 authors)
Luminescence
Published: Jul 2018
4 citations
1709 days before retraction
Identification of UGTs and BCRP as potential pharmacokinetic determinants of the natural flavonoid alpinetin
Chunli Qi, Jiangnan Fu, Hui-Nan Zhao et al. (6 authors)
Xenobiotica
Published: Feb 2018
17 citations
1872 days before retraction
Quantification and pharmacokinetics of alpinetin in rat plasma by UHPLC–MS/MS using protein precipitation coupled with dilution approach to eliminate matrix effects
Weijian Ye, Xiaoji Lin, Youting Zhang et al. (9 authors)
Journal of Pharmaceutical and Biomedical Analysis
Published: Dec 2017
20 citations
1920 days before retraction
Involvement of mitogen activated kinase kinase 7 intracellular signalling pathway in Sunitinib-induced cardiotoxicity
Samantha Cooper, Hardip Sandhu, Afthab Hussain et al. (5 authors)
Toxicology Open Access
Published: Dec 2017
18 citations
1933 days before retraction
High-resolution structure discloses the potential for allosteric regulation of mitogen-activated protein kinase kinase 7
Takayoshi Kinoshita, Takuma Hashimoto, Yuri Sogabe et al. (6 authors)
Biochemical and Biophysical Research Communications
Published: Sep 2017
10 citations
2031 days before retraction
Modulation of Aquaporins by Dietary Patterns and Plant Bioactive Compounds
Ilaria Cataldo, Anna Maggio, Patrizia Gena et al. (7 authors)
Current Medicinal Chemistry
Published: May 2017
14 citations
2135 days before retraction
The P38α rs3804451 Variant Predicts Chemotherapy Response and Survival of Patients with Non–Small Cell Lung Cancer Treated with Platinum-Based Chemotherapy
Ming Jia, Yuan Xu, Meiling Zhu et al. (8 authors)
Translational Oncology Open Access
Published: Nov 2016
3 citations
2334 days before retraction
<scp>G</scp>enetic variants of JNK and p38α pathways and risk of non‐small cell lung cancer in an <scp>E</scp>astern <scp>C</scp>hinese population
Ming Jia, Meiling Zhu, Fei Zhou et al. (13 authors)
International Journal of Cancer Open Access
Published: Nov 2016
8 citations
2337 days before retraction
Alpinetin attenuates inflammatory responses by suppressing TLR4 and NLRP3 signaling pathways in DSS-induced acute colitis
Xuexiu He, Zhengkai Wei, Jingjing Wang et al. (7 authors)
Scientific Reports Open Access
Published: Jun 2016
169 citations
2475 days before retraction
A crucial role of Cys218 in configuring an unprecedented auto-inhibition form of MAP2K7
Yuri Sogabe, Takuma Hashimoto, Takashi Matsumoto et al. (6 authors)
Biochemical and Biophysical Research Communications
Published: Mar 2016
15 citations
2572 days before retraction
Solanine-induced reactive oxygen species inhibit the growth of human hepatocellular carcinoma HepG2 cells
XUE-QIN MENG, Wei Zhang, Feng Zhang et al. (7 authors)
Oncology Letters Open Access
Published: Jan 2016
27 citations
2618 days before retraction
Effects of Serial Passage on the Characteristics and Cardiac and Neural Differentiation of Human Umbilical Cord Wharton’s Jelly-Derived Mesenchymal Stem Cells
Jianchun Lian, Shi-jie Lv, Chang Liu et al. (11 authors)
Stem Cells International Open Access
Published: Dec 2015
34 citations
2658 days before retraction
Alpinetin inhibits lung cancer progression and elevates sensitization drug-resistant lung cancer cells to cis-diammined dichloridoplatium
Jibin Lu, Lin Wu, Wei Yang et al. (4 authors)
Drug Design Development and Therapy Open Access
Published: Nov 2015
21 citations
2707 days before retraction
Silencing of the ABCC4 gene by RNA interference reverses multidrug resistance in human gastric cancer
Guangyu Zhang, Zhenran Wang, Feng Qian et al. (5 authors)
Oncology Reports Open Access
Published: Dec 2014
31 citations
3013 days before retraction
5Z-7-Oxozeaenol covalently binds to MAP2K7 at Cys218 in an unprecedented manner
Yuri Sogabe, Takashi Matsumoto, Takuma Hashimoto et al. (6 authors)
Bioorganic & Medicinal Chemistry Letters
Published: Dec 2014
26 citations
3030 days before retraction
Cytotoxicity and modes of action of 4′-hydroxy-2′,6′-dimethoxychalcone and other flavonoids toward drug-sensitive and multidrug-resistant cancer cell lines
Victor Kuete, Antoine Honoré Lonfouo Nkuété, Armelle T. Mbaveng et al. (7 authors)
Phytomedicine
Published: Sep 2014
75 citations
3119 days before retraction
The chalcones cardamonin and flavokawain B inhibit the differentiation of preadipocytes to adipocytes by activating ERK
Tianshun Zhang, Norio Yamamoto, Yoko Yamashita et al. (4 authors)
Archives of Biochemistry and Biophysics
Published: May 2014
25 citations
3240 days before retraction
Alpinetin inhibits LPS-induced inflammatory mediator response by activating PPAR-γ in THP-1-derived macrophages
Ke Hu, Yang Yu, Qiuyun Tu et al. (5 authors)
European Journal of Pharmacology
Published: Oct 2013
53 citations
3464 days before retraction
In vivo and in vitro inhibition of human liver cancer progress by downregulation of the μ-opioid receptor and relevant mechanisms
Lu Jin, Zefeng Liu, Lingling Zhao et al. (6 authors)
Oncology Reports Open Access
Published: Jul 2013
29 citations
3535 days before retraction
Alpinetin attenuates inflammatory responses by interfering toll-like receptor 4/nuclear factor kappa B signaling pathway in lipopolysaccharide-induced mastitis in mice
Haijin Chen, Xiao‐Dong Mo, Jinlong Yu et al. (4 authors)
International Immunopharmacology
Published: May 2013
42 citations
3612 days before retraction
RNA interference-mediated USP22 gene silencing promotes human brain glioma apoptosis and induces cell cycle arrest
Zhao Hui Li, Yu Yin, Chao Du et al. (6 authors)
Oncology Letters Open Access
Published: Feb 2013
40 citations
3699 days before retraction
Quick Stats
Total Citations: 41
Years Since Retraction: 2.6 years
Open Access: Yes
Last Checked: Jul 24, 2025
Related Papers
CIP2A, an oncoprotein, is associated with cell proliferatio…
Oncology Reports • 9 citations
Inhibition of neddylation modification by MLN4924 sensitize…
Oncology Reports • 21 citations
Ruscogenin induces ferroptosis in pancreatic cancer cells
Oncology Reports • 88 citations
Upregulation of estrogen receptor mediates migration, invas…
Oncology Reports • 39 citations
Inhibition of 5-lipoxygenase triggers apoptosis in pancreat…
Oncology Reports • 43 citations
Actions
More from this journal Similar subjects View Original Paper View Retraction Notice