Expression of concern
Polydeoxyribonucleotide (PDRN) restores blood flow in an experimental model of peripheral artery occlusive disease
Paper Information
Record ID:
43643
Author(s):
Journal:
Publication Date:
November 01, 2008
Retraction Date:
August 01, 2022
(3.3 years years ago)
Subject:
Broad Categories:
Medicine
Medicine
Specific Fields:
Medicine - General
Medicine - General
Country:
🇮🇹 ItalyArticle Type:
Publisher:
Elsevier
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Not indexed in PubMed
Expression of concern Details
Retraction Reasons:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1016/j.jvs.2022.06.085Citations (60)
60
Total Citations16
Post-Retraction(26.7%)
44
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
8
Within 1 year
5
After 2+ years
1073
Days since retraction (latest)
Elucidating Interactome Dynamics of the A2A Adenosine Receptor in the Presence of Polydeoxyribonucleotide
Wonseok Lee, Ahrum Son, Jaeho Ji et al. (9 authors)
Journal of Proteome Research
Published: Jul 2025
1073 days after retraction
Comparative Analysis of Melatonin and Polydeoxyribonucleotide: Possible Benefits of Co-Treatment Effects and Potential Synergistic Applicability
Su Kil Jang, Jaeseok Choi, Hye Won Lim et al. (5 authors)
International Journal of Molecular Sciences
Open Access
Published: Jun 2025
1047 days after retraction
A literature review on polynucleotide efficacy on skin rejuvenation, and review of the regulatory status and guidelines around polynucleotides
Lauren Titcomb
Journal of Aesthetic Nursing
Published: Apr 2025
975 days after retraction
Human Placenta MSC-Derived DNA Fragments Exert Therapeutic Effects in a Skin Wound Model via the A2A Receptor
H. Lee, Hyun‐Jung Lee, Hyuk Jai Jang et al. (5 authors)
International Journal of Molecular Sciences
Open Access
Published: Feb 2025
1 citation
1 citation
933 days after retraction
Polydeoxyribonucleotide enhances the bioactivities of stem cells from human exfoliated deciduous teeth through Akt activation
Yeo Gyun Yun, Dong-Hyeon Yeo, Seong‐Jin Shin et al. (6 authors)
Biochemical and Biophysical Research Communications
Published: Nov 2024
829 days after retraction
Elucidating Interactome Dynamics of the A2A Adenosine Receptor
Wonseok Lee, Ahrum Son, Woojin Kim et al. (9 authors)
Unknown Journal
Published: Jul 2024
710 days after retraction
Development and characterization of polydeoxyribonucleotide (PDRN) loaded chitosan polyplex: In vitro and in vivo evaluation of wound healing activity
S.H.S. Dananjaya, Kuruwitage Madushani, Jeewani Dilrukshi et al. (9 authors)
International Journal of Biological Macromolecules
Published: Sep 2023
11 citations
11 citations
404 days after retraction
Effect of Polydeoxyribonucleotide on Human Periodontal Ligament Cells as a Storage Medium for Avulsed Tooth
Sang Tae Ro, Yong Kwon Chae, Ko Eun Lee et al. (7 authors)
THE JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY
Open Access
Published: Aug 2023
1 citation
1 citation
388 days after retraction
Targeting Adenosine Signalling in Knee Chondropathy: The Combined Action of Polydeoxyribonucleotide and Pulsed Electromagnetic Fields: A Current Concept Review
Lorenzo Moretti, Davide Bizzoca, Alessandro Geronimo et al. (8 authors)
International Journal of Molecular Sciences
Open Access
Published: Jun 2023
3 citations
3 citations
316 days after retraction
Polydeoxyribonucleotide in the Treatment of Tendon Disorders, from Basic Science to Clinical Practice: A Systematic Review
Davide Bizzoca, Giovanni Brunetti, Lorenzo Moretti et al. (8 authors)
International Journal of Molecular Sciences
Open Access
Published: Feb 2023
10 citations
10 citations
209 days after retraction
Protective Effect of Locally Injected Polydeoxyribonucleotide in Ischemic Murine Random Skin Flaps
Jiye Kim, Jaemoon Yang, Minhee Ku et al. (9 authors)
Korean Journal of Otorhinolaryngology - Head and Neck Surgery
Open Access
Published: Feb 2023
204 days after retraction
Efficacy of Polydeoxyribonucleotide in Promoting the Healing of Diabetic Wounds in a Murine Model of Streptozotocin-Induced Diabetes: A Pilot Experiment
Ji Young Yun, SaeGwang Park, Ha Young Park et al. (4 authors)
International Journal of Molecular Sciences
Open Access
Published: Jan 2023
6 citations
6 citations
170 days after retraction
Nanocomplexes of doxorubicin and DNA fragments for efficient and safe cancer chemotherapy
Saad N. Mohammad, Yeon Su Choi, Jee Young Chung et al. (14 authors)
Journal of Controlled Release
Open Access
Published: Jan 2023
21 citations
21 citations
157 days after retraction
A chitosan derivative-crosslinked hydrogel with controllable release of polydeoxyribonucleotides for wound treatment
Yanzhen Sun, Xiaodong Jing, Yang Liu et al. (7 authors)
Carbohydrate Polymers
Published: Nov 2022
49 citations
49 citations
94 days after retraction
Polydeoxyribonucleotide: A promising skin anti-aging agent
Aawrish Khan, Guobao Wang, Feng Zhou et al. (7 authors)
Chinese Journal of Plastic and Reconstructive Surgery
Open Access
Published: Oct 2022
23 citations
23 citations
82 days after retraction
The impact of polydeoxyribonucleotide on early bone formation in lateral-window sinus floor elevation with simultaneous implant placement
Dongseob Lee, Jungwon Lee, Ki‐Tae Koo et al. (5 authors)
Journal of Periodontal & Implant Science
Open Access
Published: Oct 2022
10 citations
10 citations
66 days after retraction
Effect of epidural polydeoxyribonucleotide in a rat model of lumbar foraminal stenosis
Ho‐Jin Lee, Jiyoun Ju, Eun Joo Choi et al. (6 authors)
The Korean journal of pain
Open Access
Published: Oct 2021
10 citations
10 citations
304 days before retraction
Eradication of Intracellular <i>Salmonella</i> Typhimurium by Polyplexes of Acid‐Transforming Chitosan and Fragment DNA
Julius A. Edson, Weiping Chu, Steffen Porwollik et al. (7 authors)
Macromolecular Bioscience
Open Access
Published: Apr 2021
5 citations
5 citations
470 days before retraction
Synergetic effects of shock waves with polydeoxyribonucleotides on rotator cuff tendon tear in a rabbit model
Donghan Kim, Dong Rak Kwon, Gi-Young Park et al. (4 authors)
Biocell
Published: Jan 2021
5 citations
5 citations
577 days before retraction
Sympathetic Nerve Control of Blood Pressure Response during Exercise in Peripheral Artery Disease and Current Application of Experimental Disease Models
Jianhua Li
American Journal of Biomedical Science & Research
Open Access
Published: Jun 2020
1 citation
1 citation
767 days before retraction
Polydeoxyribonucleotide Exerts Therapeutic Effect by Increasing VEGF and Inhibiting Inflammatory Cytokines in Ischemic Colitis Rats
Sung‐Eun Kim, Il‐Gyu Ko, Jun‐Jang Jin et al. (8 authors)
BioMed Research International
Open Access
Published: Feb 2020
25 citations
25 citations
891 days before retraction
Anti-Allodynic Effects of Polydeoxyribonucleotide in an Animal Model of Neuropathic Pain and Complex Regional Pain Syndrome
Sung Hyun Lee, Sie Hyeon Yoo, Hae-Jin Lee et al. (8 authors)
Journal of Korean Medical Science
Open Access
Published: Jan 2020
14 citations
14 citations
943 days before retraction
Polydeoxyribonucleotide Activates Mitochondrial Biogenesis but Reduces MMP-1 Activity and Melanin Biosynthesis in Cultured Skin Cells
Yeon‐Ji Kim, Min-Jung Kim, Dong-Keon Kweon et al. (5 authors)
Applied Biochemistry and Biotechnology
Published: Dec 2019
30 citations
30 citations
968 days before retraction
Dynamics of Regenerative Processes in Patients with Trophic Ulcers against the Background of Chronic Venous Hemodynamic Disturbances Using Therapy with Polydesoxyrinobonucleotides
Yelena G. Shapovalova, Yuriy Baranovskiy, Fedor Ilchenko et al. (5 authors)
International Journal of Biomedicine
Open Access
Published: Jun 2019
1143 days before retraction
The efficacy and safety of BM-PHA for the correction of nasolabial folds: a multicenter, randomized, double-blind, split-face clinical trial
Seung Hwan Paik, Myoung Eun Choi, Woo Jin Lee et al. (8 authors)
Journal of Dermatological Treatment
Published: Jun 2019
1 citation
1 citation
1144 days before retraction
Effect of Polydeoxyribonucleotide on Chondrocutaneous Composite Grafts Survival
Jae Won Heo, Yong Hun Kim, Eon Su Kim et al. (5 authors)
Aesthetic Plastic Surgery
Published: May 2019
2 citations
2 citations
1168 days before retraction
An effective range of polydeoxyribonucleotides is critical for wound healing quality
Kyu‐Hee Hwang, Ji‐Hee Kim, Eun Joo Park et al. (4 authors)
Molecular Medicine Reports
Open Access
Published: Oct 2018
18 citations
18 citations
1393 days before retraction
The Effect of Polydeoxyribonucleotide on Chronic Non-healing Wound of an Amputee: A Case Report
Junho Shin, Gahee Park, Junhee Lee et al. (4 authors)
Annals of Rehabilitation Medicine
Open Access
Published: Aug 2018
14 citations
14 citations
1431 days before retraction
Comparison of wound healing effects between Oncorhynchus keta-derived polydeoxyribonucleotide (PDRN) and Oncorhynchus mykiss-derived PDRN
Jong Hun Lee, Jin Woo Han, Jin Hwan Byun et al. (6 authors)
Archives of Craniofacial Surgery
Open Access
Published: Mar 2018
20 citations
20 citations
1595 days before retraction
Treatment of Full-Thickness Rotator Cuff Tendon Tear Using Umbilical Cord Blood-Derived Mesenchymal Stem Cells and Polydeoxyribonucleotides in a Rabbit Model
Dong Rak Kwon, Gi-Young Park, Sang Chul Lee
Stem Cells International
Open Access
Published: Jan 2018
43 citations
43 citations
1673 days before retraction
Effects of salmon DNA fraction in vitro and in a monosodium iodoacetate-induced osteoarthritis rat model
Ho Jong, Mi Young Oh, Hee‐Ju Kim et al. (9 authors)
Korean Journal of Physiology and Pharmacology
Open Access
Published: Jan 2018
7 citations
7 citations
1673 days before retraction
Ultrasound-Guided Prolotherapy with Polydeoxyribonucleotide for Painful Rotator Cuff Tendinopathy
Kyoung Ho Ryu, Dongchan Ko, Goeun Lim et al. (5 authors)
Pain Research and Management
Open Access
Published: Jan 2018
27 citations
27 citations
1673 days before retraction
Polydeoxyribonucleotide improves tendon healing following achilles tendon injury in rats
Shin Hyuk Kang, Min Seok Choi, Han Koo Kim et al. (7 authors)
Journal of Orthopaedic Research®
Open Access
Published: Nov 2017
22 citations
22 citations
1733 days before retraction
Polydeoxyribonucleotide Improves Peripheral Tissue Oxygenation and Accelerates Angiogenesis in Diabetic Foot Ulcers
Seoyoung C. Kim, Jun-Hyung Kim, Jaehoon Choi et al. (5 authors)
Archives of Plastic Surgery
Open Access
Published: Oct 2017
29 citations
29 citations
1740 days before retraction
Scar Prevention and Enhanced Wound Healing Induced by Polydeoxyribonucleotide in a Rat Incisional Wound-Healing Model
Woonhyeok Jeong, Chae Eun Yang, Tai Suk Roh et al. (6 authors)
International Journal of Molecular Sciences
Open Access
Published: Aug 2017
76 citations
76 citations
1824 days before retraction
Improvement of Hair Graying during a Treatment of Male Pattern Hair Loss Using 1,927-nm Fractionated Thulium Laser Energy and Polydeoxyribonucleotide Injections
Yoon Jin Choi, Suhyun Cho, Young Koo Kim et al. (4 authors)
Medical Lasers
Open Access
Published: Jun 2017
7 citations
7 citations
1858 days before retraction
Pharmacological Activity and Clinical Use of PDRN
Francesco Squadrito, Alessandra Bitto, Natasha Irrera et al. (7 authors)
Frontiers in Pharmacology
Open Access
Published: Apr 2017
136 citations
136 citations
1923 days before retraction
Polydeoxyribonucleotides (PDRNs) From Skin to Musculoskeletal Tissue Regeneration via Adenosine A<sub>2A</sub> Receptor Involvement
Francesca Veronesi, Dante Dallari, Giacomo Sabbioni et al. (6 authors)
Journal of Cellular Physiology
Published: Mar 2017
39 citations
39 citations
1977 days before retraction
Polydeoxyribonucleotide, an Adenosine-A2A Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury
Francesco Squadrito, Antonio Micali, Mariagrazia Rinaldi et al. (16 authors)
Frontiers in Pharmacology
Open Access
Published: Jan 2017
49 citations
49 citations
2029 days before retraction
Sodium-DNA for Bone Tissue Regeneration: An Experimental Study in Rat Calvaria
Barbara Buffoli, Gaia Favero, Elisa Borsani et al. (10 authors)
BioMed Research International
Open Access
Published: Jan 2017
16 citations
16 citations
2038 days before retraction
Polydeoxyribonucleotide improves wound healing of fractional laser resurfacing in rat model
Mi Ran Yu, Jun Young Lee
Journal of Cosmetic and Laser Therapy
Published: Oct 2016
18 citations
18 citations
2111 days before retraction
Effects of polydeoxyribonucleotides (PDRN) on wound healing: Electric cell-substrate impedance sensing (ECIS)
Youngmi Koo, Yeoheung Yun
Materials Science and Engineering C
Published: Jul 2016
31 citations
31 citations
2220 days before retraction
Protective Effect of Polydeoxyribonucleotide Against Renal Ischemia-Reperfusion Injury in Mice
Eun-Mi Jeong, Hyuk Jai Jang, S.S. Kim et al. (9 authors)
Transplantation Proceedings
Published: May 2016
16 citations
16 citations
2283 days before retraction
Inhibition of Prostaglandin Transporter (PGT) Promotes Perfusion and Vascularization and Accelerates Wound Healing in Non-Diabetic and Diabetic Rats
Zhongbo Liu, Outhiriaradjou Benard, Mahrukh M. Syeda et al. (5 authors)
PLoS ONE
Open Access
Published: Jul 2015
20 citations
20 citations
2558 days before retraction
The Effect of Polydeoxyribonucleotide on Ischemic Rat Skin Flap Survival
Dong Won Lee, Hyun Joon Hong, Huyn Roh et al. (4 authors)
Annals of Plastic Surgery
Published: May 2015
21 citations
21 citations
2642 days before retraction
FGFR1 mediates recombinant thrombomodulin domain-induced angiogenesis
Cheng‐Hsiang Kuo, Meng-Chen Sung, Po-Ku Chen et al. (12 authors)
Cardiovascular Research
Open Access
Published: Nov 2014
34 citations
34 citations
2820 days before retraction
Polyethylene Glycol Formulations Show Different Soft Tissue Remodeling and Angiogenesis Features
Giacomo Oteri, Gabriele Pizzino, Michele Pisano et al. (6 authors)
Tissue Engineering Part A
Open Access
Published: Oct 2014
5 citations
5 citations
2860 days before retraction
Trophic effects of polynucleotides and hyaluronic acid in the healing of venous ulcers of the lower limbs: a clinical study
Giovanni De Caridi, Mafalda Massara, Ignazio Eduardo Acri et al. (8 authors)
International Wound Journal
Open Access
Published: Sep 2014
37 citations
37 citations
2876 days before retraction
Corrigenda
Francesco Squadrito, Alessandra Bitto, Domenica Altavilla et al. (13 authors)
The Journal of Clinical Endocrinology & Metabolism
Open Access
Published: Jan 2014
66 citations
66 citations
3104 days before retraction
Quantitation of Polydeoxyribonucletides (PDRNs) in Human Placental Extract by Fluorescence Spectroscopy Using Ethidium Bromide
Piyali Datta Chakraborty, Sutapa Goswami, Sudipta Bera et al. (4 authors)
American Journal of Analytical Chemistry
Open Access
Published: Jan 2014
3 citations
3 citations
3134 days before retraction
Quick Stats
Total Citations:
60
Years Since Retraction:
3.3 years
Open Access:
Yes
Last Checked:
Jul 24, 2025