Retraction

The hypoxic cancer secretome induces pre-metastatic bone lesions through lysyl oxidase

Paper Information

Record ID:
43891
Author(s):
Thomas R Cox
Robin M H Rumney
Erwin M Schoof
Lara Perryman
Anette M Hoye
Ankita Agrawal
Demelza Bird
Norain Ab Latif
Hamish Forrest
Holly R Evans
Iain D Huggins
Goergina Lang
Rune Linding
Alison Gartland
Janine T Erler
Journal:
Nature ( Springer - Nature Publishing Group )
Publication Date:
May 27, 2015
Retraction Date:
April 17, 2023 (2.6 years years ago)
Subjects:
Broad Categories:
Medicine Biology Biochemistry
Institutions:
Countries:
🇩🇰 Denmark 🇬🇧 United Kingdom
Article Type:
Research Article
Publisher:
Springer - Nature Publishing Group
Open Access:
Yes
DOI:
10.1038/nature14492
PubMed ID:
26017313
Retraction PubMed ID:
37069265

Retraction Details

Retraction Reasons:
Nature of Retraction:

Retraction

Retraction Notice:
10.1038/s41586-023-06048-x

Citations (457)

457
Total Citations
26
Post-Retraction
(5.7%)
430
Pre-Retraction
0
Same Day
Post-Retraction Citation Analysis
1 Within 30 days
17 Within 1 year
0 After 2+ years
722 Days since retraction (latest)
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Frontiers in Immunology Open Access
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International Journal of Oncology Open Access
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229 citations
1932 days before retraction
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1932 days before retraction
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1932 days before retraction
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Oncogene
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Lysyl oxidase activates cancer stromal cells and promotes gastric cancer progression: quantum dot-based identification of biomarkers in cancer stromal cells
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International Journal of Nanomedicine Open Access
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Elsevier eBooks
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11 citations
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Aaron E. Chiou, Claudia Fischbach
Cancer drug discovery and develogment/Cancer drug discovery and development
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2005 days before retraction
Hypoxia inducible factor (HIF) in the tumor microenvironment: friend or foe?
Yanqing Huang, Daniel Lin, Cullen M. Taniguchi
Science China Life Sciences Open Access
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Nature reviews. Cancer
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miRNAs in bone metastasis
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Expert Review of Endocrinology & Metabolism
Published: Sep 2017
3 citations
2033 days before retraction
Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis
Frank He, Aaron E. Chiou, Hyun Chae Loh et al. (16 authors)
Proceedings of the National Academy of Sciences Open Access
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63 citations
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Introductory review: periostin—gene and protein structure
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Cellular and Molecular Life Sciences
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Cancer Research Open Access
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2055 days before retraction
Extranodal spread of primary and secondary metastatic nodes: The dominant risk factor of survival in patients with head and neck squamous cell carcinoma
Misa Sumi, Shuntaro Sato, Takashi Nakamura
PLoS ONE Open Access
Published: Aug 2017
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Kazuo Okamoto, Tomoki Nakashima, Masahiro Shinohara et al. (9 authors)
Physiological Reviews Open Access
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458 citations
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Journal of Materials Science Materials in Medicine
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33 citations
2099 days before retraction
Lysyl Oxidase–like Protein LOXL2 Promotes Lung Metastasis of Breast Cancer
Fernando Salvador, Alberto Martín, Celia López‐Menéndez et al. (15 authors)
Cancer Research Open Access
Published: Jul 2017
137 citations
2099 days before retraction
Metastasis ‘systems’ biology: how are macro-environmental signals transmitted into microenvironmental cues for disseminated tumor cells?
Candice Alexandra Grzelak, Cyrus M. Ghajar
Current Opinion in Cell Biology Open Access
Published: Jul 2017
21 citations
2102 days before retraction
Proteomic profiling of the cancer cell secretome: informing clinical research
Yen-Chang Hsiao, Lichieh Julie Chu, Jeng-Ting Chen et al. (5 authors)
Expert Review of Proteomics
Published: Jul 2017
20 citations
2106 days before retraction
Pulsed Electron Paramagnetic Resonance Insights into the Ligand Environment of Copper in Drosophila Lysyl Oxidase
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Biochemistry Open Access
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6 citations
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Molecular Biology of the Cell Open Access
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2133 days before retraction
Engineering the pre-metastatic niche
Brian A. Aguado, Grace G. Bushnell, Shreyas S. Rao et al. (5 authors)
Nature Biomedical Engineering Open Access
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2134 days before retraction
ISDoT: in situ decellularization of tissues for high-resolution imaging and proteomic analysis of native extracellular matrix
Alejandro E. Mayorca‐Guiliani, Chris D. Madsen, Thomas R. Cox et al. (6 authors)
Nature Medicine
Published: Jun 2017
171 citations
2135 days before retraction
Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF‐1α synthesis, and decreases breast cancer metastasis
Zhonghong Wei, Yunlong Shan, Tao Li et al. (10 authors)
Molecular Carcinogenesis
Published: Jun 2017
82 citations
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RIP4 inhibits STAT3 signaling to sustain lung adenocarcinoma differentiation
Jawahar Kopparam, Johanna Chiffelle, Paolo Angelino et al. (7 authors)
Cell Death and Differentiation Open Access
Published: Jun 2017
29 citations
2145 days before retraction
Postmenopausal breast cancer: European challenge and innovative concepts
Ivica Smokovski, Milan Risteski, Jiří Polívka et al. (7 authors)
The EPMA Journal Open Access
Published: May 2017
30 citations
2148 days before retraction
Hypoxic pathobiology of breast cancer metastasis
Luana Schito, Sergio Rey
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
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55 citations
2162 days before retraction
Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth
Anisha M. Hammer, Gina M. Sizemore, Vasudha Shukla et al. (16 authors)
Neoplasia Open Access
Published: May 2017
62 citations
2167 days before retraction
Pathophysiology of bone metastases from solid malignancies
Philippe Clézardin
Joint Bone Spine
Published: May 2017
47 citations
2169 days before retraction
Osteoclast inhibition in postmenopausal breast cancer: Is the evidence too strong to ignore?
Alison Stopeck
Cancer Open Access
Published: May 2017
3 citations
2176 days before retraction
Roles of Copper-Binding Proteins in Breast Cancer
Stéphanie Blockhuys, Pernilla Wittung‐Stafshede
International Journal of Molecular Sciences Open Access
Published: Apr 2017
93 citations
2188 days before retraction
Context-dependent intravital imaging of therapeutic response using intramolecular FRET biosensors
James R. W. Conway, Sean Warren, Paul Timpson
Methods
Published: Apr 2017
42 citations
2189 days before retraction
Lysyl oxidase drives tumour progression by trapping EGF receptors at the cell surface
Haoran Tang, Leo Leung, Grazia Saturno et al. (13 authors)
Nature Communications Open Access
Published: Apr 2017
82 citations
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Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma
Gemma Di Pompo, Silvia Lemma, Lorenzo Canti et al. (12 authors)
Oncotarget Open Access
Published: Apr 2017
40 citations
2195 days before retraction
Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases
Chen Rachman-Tzemah, Shelly Zaffryar‐Eilot, Moran Grossman et al. (12 authors)
Cell Reports Open Access
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94 citations
2207 days before retraction
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Hong-Yan Xie, Zhimin Shao, Da‐Qiang Li
Chinese Journal of Cancer Open Access
Published: Mar 2017
60 citations
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Jürgen Dittmer
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Published: Mar 2017
76 citations
2216 days before retraction
Quick Stats
Total Citations: 457
Years Since Retraction: 2.6 years
Open Access: Yes
Last Checked: Jul 24, 2025
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