Expression of concern
Genetic Polymorphisms of Dihydropyrimidinase in a Japanese Patient with Capecitabine-Induced Toxicity
Paper Information
Record ID:
44281
Author(s):
Publication Date:
April 27, 2015
Retraction Date:
January 11, 2023
(2.9 years years ago)
Subjects:
Institutions:
Country:
🇯🇵 JapanArticle Type:
Publisher:
PLoS
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Expression of concern Details
Retraction Reason:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1371/journal.pone.0279458Citations (23)
23
Total Citations3
Post-Retraction(13.0%)
19
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
0
Within 30 days
1
Within 1 year
0
After 2+ years
678
Days since retraction (latest)
Juvenile Parkinsonism Associated With Dihydropyrimidinase Deficiency
Jiaqing Li, Sanqing Xu
PEDIATRICS
Published: Nov 2024
678 days after retraction
Common dihydropyrimidinase (DPYS) genetic variations do not predict fluoropyrimidine-related chemotherapy toxicity in a Canadian cohort
Samantha Medwid, Jaymie Mailloux, Theodore J. Wigle et al. (4 authors)
Pharmacogenetics and Genomics
Published: Jan 2024
366 days after retraction
The burden of rare variants in DPYS gene is a novel predictor of the risk of developing severe fluoropyrimidine-related toxicity
Elena De Mattia, Jerry Polesel, Marco Silvestri et al. (10 authors)
Human Genomics
Open Access
Published: Nov 2023
8 citations
8 citations
302 days after retraction
Expression of Concern: Genetic Polymorphisms of Dihydropyrimidinase in a Japanese Patient with Capecitabine-Induced Toxicity
Unknown Authors
PLoS ONE
Open Access
Published: Jan 2023
Same day as retraction
Functional Characterization of 12 Dihydropyrimidinase Allelic Variants in Japanese Individuals for the Prediction of 5-Fluorouracil Treatment-Related Toxicity
Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico et al. (15 authors)
Drug Metabolism and Disposition
Published: Nov 2022
4 citations
4 citations
50 days before retraction
Transcriptome Profile Based on Protein-Protein Interaction Networks Provides a Set of Core Genes for Understanding the Metabolic Mechanisms of the Egg-Protecting Behavior in Amphioctopus fangsiao
Xiaokai Bao, Zan Li, Jianbai Zhang et al. (11 authors)
Journal of Ocean University of China
Published: Sep 2022
121 days before retraction
Structural investigation of pathogenic variants in dihydropyrimidinase using molecular dynamics simulations
Koichi Kato, Tomoki Nakayoshi, Ayuka Nagura et al. (7 authors)
Journal of Molecular Graphics and Modelling
Published: Aug 2022
2 citations
2 citations
158 days before retraction
Importance of Rare DPYD Genetic Polymorphisms for 5-Fluorouracil Therapy in the Japanese Population
Eiji Hishinuma, Yoko Narita, Kai Obuchi et al. (11 authors)
Frontiers in Pharmacology
Open Access
Published: Jun 2022
18 citations
18 citations
210 days before retraction
In Vitro Assessment of Fluoropyrimidine-Metabolizing Enzymes: Dihydropyrimidine Dehydrogenase, Dihydropyrimidinase, and β-Ureidopropionase
Eiji Hishinuma, Evelyn Marie Gutiérrez Rico, Masahiro Hiratsuka
Journal of Clinical Medicine
Open Access
Published: Jul 2020
11 citations
11 citations
903 days before retraction
Impact of <i>DPYD</i>, <i>DPYS</i>, and <i>UPB1</i> gene variations on severe drug‐related toxicity in patients with cancer
Katsuyuki Yokoi, Yoko Nakajima, Hiroshi Matsuoka et al. (13 authors)
Cancer Science
Open Access
Published: Jul 2020
17 citations
17 citations
922 days before retraction
A novel stop-gain mutation in DPYS gene causing Dihidropyrimidinase deficiency, a case report
Malihe Mirzaei, Arghavan Kavosi, Mahboobeh Sharifzadeh et al. (7 authors)
BMC Medical Genetics
Open Access
Published: Jun 2020
5 citations
5 citations
926 days before retraction
Anticancer activity of lanthanum (III) and europium (III) 5‐fluorouracil complexes on Caco‐2 cell line
Nagwa Abo El‐Maali, Asmaa Y. Wahman, Aref A. M. Aly et al. (5 authors)
Applied Organometallic Chemistry
Published: Mar 2020
15 citations
15 citations
1027 days before retraction
DPYD and Fluorouracil-Based Chemotherapy: Mini Review and Case Report
Theodore J. Wigle, Elena Tsvetkova, Stephen Welch et al. (4 authors)
Pharmaceutics
Open Access
Published: May 2019
77 citations
77 citations
1351 days before retraction
Pharmacogenetics of hepatocellular carcinoma and cholangiocarcinoma
Marta Alonso‐Peña, Anabel Sánchez-Martín, Paula Sanchon-Sanchez et al. (6 authors)
Cancer Drug Resistance
Open Access
Published: Jan 2019
7 citations
7 citations
1471 days before retraction
A case of dihydropyrimidinase deficiency incidentally detected by urine metabolome analysis
Hiroki Tsuchiya, Tomoyuki Akiyama, Tomiko Kuhara et al. (10 authors)
Brain and Development
Published: Oct 2018
8 citations
8 citations
1535 days before retraction
Dihydropyrimidinase deficiency in four East Asian patients due to novel and rare DPYS mutations affecting protein structural integrity and catalytic activity
Yoko Nakajima, Judith Meijer, Doreen Dobritzsch et al. (12 authors)
Molecular Genetics and Metabolism
Published: Oct 2017
23 citations
23 citations
1917 days before retraction
Functional characterization of 21 allelic variants of dihydropyrimidinase
Eiji Hishinuma, Fumika Akai, Yoko Narita et al. (9 authors)
Biochemical Pharmacology
Published: Jun 2017
13 citations
13 citations
2031 days before retraction
Suivi thérapeutique du 5-fluorouracile (5-FU)
M. Boisdron‐Celle, Érick Gamelin, Alain Morel
EMC - Biologie Médicale
Published: Jan 2017
2201 days before retraction
Determining the optimal 5-FU therapeutic dosage in the treatment of colorectal cancer patients
Ling Fang, Yi Jiang, Yuxian Yang et al. (11 authors)
Oncotarget
Open Access
Published: Sep 2016
26 citations
26 citations
2312 days before retraction
Improving safety of fluoropyrimidine chemotherapy by individualizing treatment based on dihydropyrimidine dehydrogenase activity – Ready for clinical practice?
Didier Meulendijks, Annemieke Cats, Jos H. Beijnen et al. (4 authors)
Cancer Treatment Reviews
Published: Aug 2016
92 citations
92 citations
2340 days before retraction
Altered Pre-mRNA Splicing Caused by a Novel Intronic Mutation c.1443+5G>A in the Dihydropyrimidinase (DPYS) Gene
Yoko Nakajima, Judith Meijer, Chunhua Zhang et al. (8 authors)
International Journal of Molecular Sciences
Open Access
Published: Jan 2016
10 citations
10 citations
2556 days before retraction
Dihydropyrimidinase Deficiency with Severe 5-fluorouracil Toxicity Caused by Capecitabine
Hiroshi Yamashita, Masahiro Hiratsuka, Takahiro Mori et al. (10 authors)
The Japanese Journal of Gastroenterological Surgery
Open Access
Published: Jan 2015
2932 days before retraction
Quick Stats
Total Citations:
23
Years Since Retraction:
2.9 years
Open Access:
Yes
Last Checked:
Jul 24, 2025