Expression of concern
Impact of the Superoxide Dismutase 2 Val16Ala Polymorphism on the Relationship between Valproic Acid Exposure and Elevation of γ-Glutamyltransferase in Patients with Epilepsy: A Population Pharmacokinetic-Pharmacodynamic Analysis
Paper Information
Record ID:
44811
Author(s):
Publication Date:
November 05, 2014
Retraction Date:
January 11, 2023
(2.9 years years ago)
Subject:
Broad Categories:
Medicine
Medicine
Specific Fields:
Medicine - Pharmacology
Medicine - Pharmacology
Institutions:
- Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
- Department of Neuropsychiatry, Hirosaki University School of Medicine, Hirosaki, Japan
- Kumamoto Saishunso National Hospital, Kumamoto, Japan
- Kumamoto Ezuko Ryoiku Iryo Center, Kumamoto, Japan
- Division of Pharmacology and Therapeutics, Graduate School of Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
- Center for Clinical Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan
Country:
🇯🇵 JapanArticle Type:
Publisher:
PLoS
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Expression of concern Details
Retraction Reason:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1371/journal.pone.0279162Citations (36)
36
Total Citations7
Post-Retraction(19.4%)
28
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
0
Within 30 days
2
Within 1 year
0
After 2+ years
667
Days since retraction (latest)
Combined carbapenem resulted in a 4.48-fold increase in valproic acid clearance: a population pharmacokinetic model in Chinese children and adults with epilepsy or after neurosurgery
Luofei Zhang, Ruoyun Wu, Xingmeng Li et al. (6 authors)
Frontiers in Pharmacology
Open Access
Published: Nov 2024
667 days after retraction
Fixed parameters in the population pharmacokinetic modeling of valproic acid might not be suitable: external validation in Chinese adults with epilepsy or after neurosurgery
Ruoyun Wu, Kai Li, Zhigang Zhao et al. (4 authors)
European Journal of Clinical Pharmacology
Published: Aug 2024
1 citation
1 citation
596 days after retraction
Population pharmacokinetics of valproic acid in children with epilepsy: Implications for dose tailoring when switching from oral syrup to sustained‐release tablets
Weijun Wang, Yue Li, Ya‐Hui Hu et al. (10 authors)
CPT Pharmacometrics & Systems Pharmacology
Published: Jun 2024
1 citation
1 citation
530 days after retraction
Retrospective Analysis of Steady-State Sodium Valproate Plasma Concentrations in Chinese Patients With Bipolar Disorder: Impact of Demographic and Clinical Characteristics
Qian Qiming, Ping Zheng, Huiqi Li et al. (6 authors)
Therapeutic Drug Monitoring
Open Access
Published: Apr 2024
464 days after retraction
Sex differences in the susceptibility to valproic acid-associated liver injury in epileptic patients
Linfeng Ma, Dan Wang
Clinical Toxicology
Published: Feb 2024
3 citations
3 citations
386 days after retraction
Modeling the protein binding non-linearity in population pharmacokinetic model of valproic acid in children with epilepsy: a systematic evaluation study
Lina Zhang, Maochang Liu, Weiwei Qin et al. (6 authors)
Frontiers in Pharmacology
Open Access
Published: Oct 2023
4 citations
4 citations
268 days after retraction
Development and Internal Validation of Machine Learning Algorithms for Determining Sodium Valproate Concentrations below the Standard Level Using a Risk Prediction Model of Children with Epilepsy
Yinhui Yao, Jingyi Zhao, Ying Wang et al. (6 authors)
Journal of Clinical Pharmacy and Therapeutics
Open Access
Published: Sep 2023
254 days after retraction
Expression of Concern: Impact of the Superoxide Dismutase 2 Val16Ala Polymorphism on the Relationship between Valproic Acid Exposure and Elevation of γ-Glutamyltransferase in Patients with Epilepsy: A Population Pharmacokinetic-Pharmacodynamic Analysis
Unknown Authors
PLoS ONE
Open Access
Published: Jan 2023
Same day as retraction
Effect of ANKK1 Polymorphisms on Serum Valproic Acid Concentration in Chinese Han Adult Patients in the Early Postoperative Period
Jiuhong Ma, Xiuzhao Fan, Xinfeng Cai et al. (6 authors)
Neurology and Therapy
Open Access
Published: Nov 2022
54 days before retraction
Comparative pharmacokinetics of valproic acid among Pakistani and South Korean patients: A population pharmacokinetic study
Muhammad Usman, Qurrat-ul-Ain Shaukat, Muhammad Imran Khokhar et al. (8 authors)
PLoS ONE
Open Access
Published: Aug 2022
6 citations
6 citations
140 days before retraction
Published population pharmacokinetic models of valproic acid in adult patients: a systematic review and external validation in a Chinese sample of inpatients with bipolar disorder
Yannan Zang, Wei Guo, Fang Dong et al. (6 authors)
Expert Review of Clinical Pharmacology
Published: May 2022
9 citations
9 citations
252 days before retraction
Population Pharmacokinetics of Valproic Acid in Pediatric and Adult Caucasian Patients
Paulo Teixeira-da-Silva, Jonás Samuel Pérez‐Blanco, Dolores Santos‐Buelga et al. (5 authors)
Pharmaceutics
Open Access
Published: Apr 2022
13 citations
13 citations
279 days before retraction
Population pharmacokinetics of valproic acid in adult Chinese patients with bipolar disorder
Yannan Zang, Wei Guo, Meng-Xi Niu et al. (9 authors)
European Journal of Clinical Pharmacology
Published: Dec 2021
15 citations
15 citations
405 days before retraction
Effect of CYP2C19 polymorphisms on serum valproic level acid in Chinese Han patients with schizophrenia
S. Wang, Jinlong Li, Mingfen Song et al. (8 authors)
Scientific Reports
Open Access
Published: Nov 2021
15 citations
15 citations
407 days before retraction
Valproic Acid After Neurosurgery Induces Elevated Risk of Liver Injury: A Prospective Nested Case-Control Study
Jinlin Guo, Jiuhong Ma, Shan Wang et al. (8 authors)
Annals of Pharmacotherapy
Published: Nov 2021
7 citations
7 citations
429 days before retraction
Evaluation of Factors Impacting the Efficacy of Single or Combination Therapies of Valproic Acid, Carbamazepine, and Oxcarbazepine: A Longitudinal Observation Study
Qilin Peng, Mubai Ma, Xurui Gu et al. (5 authors)
Frontiers in Pharmacology
Open Access
Published: May 2021
8 citations
8 citations
617 days before retraction
Predictive ability of published population pharmacokinetic models of valproic acid in Thai manic patients
Janthima Methaneethorn, Nattawut Leelakanok
Journal of Clinical Pharmacy and Therapeutics
Open Access
Published: Sep 2020
4 citations
4 citations
835 days before retraction
Remedial dosing recommendations for delayed or missed doses of valproic acid in patients with epilepsy based on Monte Carlo simulations
Chenyu Wang, Zheng Jiao, Junjie Ding et al. (5 authors)
Epilepsy & Behavior
Published: Jul 2020
20 citations
20 citations
920 days before retraction
Pharmacogenomics of Cognitive Dysfunction and Neuropsychiatric Disorders in Dementia
Ramón Cacabelos
International Journal of Molecular Sciences
Open Access
Published: Apr 2020
50 citations
50 citations
990 days before retraction
Pharmacogenomics of drugs used to treat brain disorders
Ramón Cacabelos
Expert Review of Precision Medicine and Drug Development
Published: Mar 2020
20 citations
20 citations
1030 days before retraction
Apoptotic Markers Are Increased in Epilepsy Patients: A Relation with Manganese Superoxide Dismutase Ala16Val Polymorphism and Seizure Type through IL-1<i>β</i> and IL-6 Pathways
Aline Kegler, Ana Letícia Fornari Caprara, Eduardo Tanuri Pascotini et al. (10 authors)
BioMed Research International
Open Access
Published: Mar 2020
19 citations
19 citations
1041 days before retraction
<i>SOD2</i> genetic polymorphism (rs4880) has no impact on 6‐month response to antidepressant treatment and inflammatory biomarkers in depressed patients
Abd El Kader Ait Tayeb, Laurent Becquemont, Khalil El‐Asmar et al. (10 authors)
Basic & Clinical Pharmacology & Toxicology
Open Access
Published: Jan 2020
7 citations
7 citations
1101 days before retraction
Catalase C-262T Polymorphism Is a Risk Factor for Valproic Acid–Induced Abnormal Liver Function in Chinese Patients With Epilepsy
Linfeng Ma, Yue Pan, Ming Sun et al. (6 authors)
Therapeutic Drug Monitoring
Published: Nov 2018
14 citations
14 citations
1519 days before retraction
Simulations of Valproate Doses Based on an External Evaluation of Pediatric Population Pharmacokinetic Models
Manon Tauzin, Jean‐Marc Tréluyer, Rima Nabbout et al. (13 authors)
The Journal of Clinical Pharmacology
Published: Nov 2018
9 citations
9 citations
1524 days before retraction
Effect of CYP2C19, UGT1A8, and UGT2B7 on valproic acid clearance in children with epilepsy: a population pharmacokinetic model
Shenghui Mei, Weixing Feng, Leting Zhu et al. (10 authors)
European Journal of Clinical Pharmacology
Published: Apr 2018
29 citations
29 citations
1730 days before retraction
A systematic review of population pharmacokinetics of valproic acid
Janthima Methaneethorn
British Journal of Clinical Pharmacology
Open Access
Published: Jan 2018
97 citations
97 citations
1825 days before retraction
Individualized Dosing Algorithms and Therapeutic Monitoring for Antiepileptic Drugs
Sven C. van Dijkman, Sebastian G. Wicha, Meindert Danhof et al. (4 authors)
Clinical Pharmacology & Therapeutics
Open Access
Published: Jun 2017
22 citations
22 citations
2024 days before retraction
Biomarkers in epilepsy–A modelling perspective
Sven C. van Dijkman, Rob A. Voskuyl, Elizabeth C. M. de Lange
European Journal of Pharmaceutical Sciences
Open Access
Published: May 2017
8 citations
8 citations
2065 days before retraction
Pharmacogenomics in epilepsy
Simona Balestrini, Sanjay M. Sisodiya
Neuroscience Letters
Open Access
Published: Jan 2017
138 citations
138 citations
2192 days before retraction
Valproic Acid
Wayne R. Snodgrass, Chia Wei Hsu
Springer eBooks
Published: Jan 2017
1 citation
1 citation
2201 days before retraction
Influence of the cytochrome P450 2D6 *10/*10 genotype on the pharmacokinetics of paroxetine in Japanese patients with major depressive disorder
Miki Nishimura, Mikito Ueda, Junji Saruwatari et al. (13 authors)
Pharmacogenetics and Genomics
Published: May 2016
4 citations
4 citations
2430 days before retraction
The Role of Pharmacogenetics in Pharmacovigilance of Psychotropic Drugs
Alessandro Serretti, Chiara Fabbri
Springer eBooks
Published: Dec 2015
2591 days before retraction
Determination of the Optimal Concentration of Valproic Acid in Patients with Epilepsy: A Population Pharmacokinetic-Pharmacodynamic Analysis
Hiroo Nakashima, Kentaro Oniki, Miki Nishimura et al. (11 authors)
PLoS ONE
Open Access
Published: Oct 2015
35 citations
35 citations
2640 days before retraction
The pharmacogenomics of epilepsy
Valentina Franco, Emilio Perucca
Expert Review of Neurotherapeutics
Published: Aug 2015
47 citations
47 citations
2694 days before retraction
<i>Cytochrome P450 2C19</i>polymorphisms and valproic acid-induced weight gain
Madoka Noai, Hiromi Soraoka, Ayami Kajiwara et al. (8 authors)
Acta Neurologica Scandinavica
Published: Jul 2015
48 citations
48 citations
2722 days before retraction
Valproic Acid
Wayne R. Snodgrass, Chia Wei Hsu
Springer eBooks
Published: Jan 2015
2932 days before retraction
Quick Stats
Total Citations:
36
Years Since Retraction:
2.9 years
Open Access:
Yes
Last Checked:
Jul 24, 2025