Retraction
Effects of flavocoxid, a dual inhibitor of COX and 5-lipoxygenase enzymes, on benign prostatic hyperplasia
Paper Information
Record ID:
44991
Author(s):
Journal:
Publication Date:
April 03, 2012
Retraction Date:
June 02, 2023
(2.5 years years ago)
Subjects:
Institutions:
- Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Messina, Italy
- Department of Biochemical, Physiological and Nutritional Sciences, Section of Physiology and Human Nutrition, University of Messina, Messina, Italy
- Department of Urology, University of Messina, Messina, Italy
- Department of Medical Affairs, Primus Pharmaceuticals Inc., Scottsdale, Arizona, USA
Countries:
Article Type:
Publisher:
Wiley
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (69)
69
Total Citations5
Post-Retraction(7.2%)
64
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
3
Within 1 year
0
After 2+ years
579
Days since retraction (latest)
Cell Metabolomics to Reveal the Mechanism of Saponins and Alkaloids on Prostate Inflammation Via Cox and Lox Pathways
Lijuan Xue, Lili Liu, Guoqiang Hou et al. (7 authors)
Unknown Journal
Published: Jan 2025
579 days after retraction
<i>N</i>‐Substituted‐5‐ [(2,5‐Dihydroxybenzyl)amino]salicylamides as Lavendustin Analogs: Antiproliferative Activity, <scp>COMPARE</scp> Analyses, Mechanistic, Docking, <scp>ADMET</scp> and Toxicity Studies
Hajjaj H.M. Abdu-Allah, Mohamed K. S. El‐Nagar, Wesam S. Qayed et al. (7 authors)
Chemical Biology & Drug Design
Published: Jan 2025
579 days after retraction
Ixeris polycephala extract alleviates progression of benign prostatic hyperplasia in rats
Eun Bok Baek, Youn–Hwan Hwang, Eun-Ju Hong et al. (5 authors)
Research Square (Research Square)
Open Access
Published: May 2024
364 days after retraction
Enhancing date seed phenolic bioaccessibility in soft cheese through a dehydrated liposome delivery system and its effect on testosterone-induced benign prostatic hyperplasia in rats
Dina Mostafa Mohammed, Tamer M. El‐Messery, Denis Baranenko et al. (6 authors)
Frontiers in Nutrition
Open Access
Published: Dec 2023
5 citations
5 citations
199 days after retraction
Common salt aggravated pathology of testosterone-induced benign prostatic hyperplasia in adult male Wistar rat
Idris Idowu Bello, Akinyinka Omigbodun, Imran Morhason‐Bello
BMC Urology
Open Access
Published: Dec 2023
2 citations
2 citations
192 days after retraction
Experimental Evaluation of 3-meta-Pyridine-1,2,4-Oxadiazole Derivative of Deoxycholic Acid as a Prototype of 5-α-Reductase Inhibitors in In Silico and In Vivo Models
Yulia V. Meshkova, Dmitry S. Baev, И. В. Сорокина et al. (8 authors)
Russian Journal of Bioorganic Chemistry
Published: Feb 2023
1 citation
1 citation
121 days before retraction
Experimental Assessment of 3-<i>meta</i>-Pyridine-1,2,4-Oxadiazole Deoxycholic Acid Derivative as a Prototype of 5-α-Reductase Inhibitors <i>in silico</i> and <i>in vivo</i> Models
Yulia V. Meshkova, Dmitry S. Baev, И. В. Сорокина et al. (8 authors)
Биоорганическая химия
Published: Jan 2023
152 days before retraction
Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia
Mohammed E. Abo‐El Fetoh, Maha M. Abdel‐Fattah, Wafaa R. Mohamed et al. (5 authors)
Inflammopharmacology
Open Access
Published: Dec 2022
15 citations
15 citations
153 days before retraction
Common Salt Aggravated Pathophysiology of Testosterone-Induced Benign Prostatic Hyperplasia in Adult Male Wistar Rat
Idris Idowu Bello, Akinyinka Omigbodun, Imran Morhason‐Bello
Research Square (Research Square)
Open Access
Published: Dec 2022
163 days before retraction
Inhibitory effects of Hydrocotyle ramiflora on testosterone-induced benign prostatic hyperplasia in rats
Suyoung Park, Youn–Hwan Hwang, Eun-Bok Baek et al. (6 authors)
International Urology and Nephrology
Published: Sep 2022
260 days before retraction
A Combination of Natural Products, BenPros (Green Tea Extract, Soybean Extract and Camellia Japonica Oil), Ameliorates Benign Prostatic Hyperplasia
Subin Oh, Moon Ho, Jin A. Shin et al. (7 authors)
Applied Sciences
Open Access
Published: Jun 2022
3 citations
3 citations
351 days before retraction
Ameliorative effect of flavocoxid on cyclophosphamide-induced cardio and neurotoxicity via targeting the GM-CSF/NF-κB signaling pathway
Fatma F. Elsayed, Waad M. Elshenawy, E.M. Khalifa et al. (5 authors)
Environmental Science and Pollution Research
Open Access
Published: May 2022
14 citations
14 citations
382 days before retraction
Nutraceuticals: A New Challenge against Cadmium-Induced Testicular Injury
Herbert Marini, Antonio Micali, Giovanni Squadrito et al. (7 authors)
Nutrients
Open Access
Published: Feb 2022
33 citations
33 citations
483 days before retraction
Effect of rape flower on benign prostatic hyperplasia in rats
Song-Chan Han, Young-Hak Yun
Brazilian Journal of Pharmaceutical Sciences
Open Access
Published: Jan 2022
1 citation
1 citation
517 days before retraction
The bioactive alkaloids identified from Cortex Phellodendri ameliorate benign prostatic hyperplasia via LOX-5/COX-2 pathways
Siqi Wang, David Yue-Wei Lee, Ying Shang et al. (9 authors)
Phytomedicine
Published: Oct 2021
23 citations
23 citations
590 days before retraction
Natural Inhibitors against Potential Targets of Cyclooxygenase, Lipoxygenase and Leukotrienes
Anil K. Saxena, Sisir Nandi, Rishita Dey et al. (5 authors)
Combinatorial Chemistry & High Throughput Screening
Published: Sep 2021
12 citations
12 citations
623 days before retraction
World Journal of Pharmaceutical Sciences
Publisher Atom and Cell Publishers
World Journal of Pharmaceutical Sciences
Published: Sep 2021
87 citations
87 citations
638 days before retraction
Flavocoxid halts both intestinal and extraintestinal alterations in acetic acid-induced colitis in rats
Nagwa I. Mohamed, Dalia H. El‐Kashef, Ghada M. Suddеk
Environmental Science and Pollution Research
Published: Aug 2021
6 citations
6 citations
646 days before retraction
Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia cell lines
Mariana Teixeira Santos Figueiredo Salgado, Alessandra Costa Lopes, Estela Fernandes e Silva et al. (11 authors)
Prostaglandins & Other Lipid Mediators
Published: May 2021
1 citation
1 citation
755 days before retraction
Pharmacological Effects and Potential Clinical Usefulness of Polyphenols in Benign Prostatic Hyperplasia
Kensuke Mitsunari, Yasuyoshi Miyata, Tomohiro Matsuo et al. (10 authors)
Molecules
Open Access
Published: Jan 2021
32 citations
32 citations
867 days before retraction
Curcumin for the Treatment of Prostate Diseases: A Systematic Review of Controlled Clinical Trials
Mohammad Bagherniya, Gholamreza Askari, Babak Alikiaii et al. (8 authors)
Advances in experimental medicine and biology
Published: Jan 2021
7 citations
7 citations
882 days before retraction
The LPS-Treated Human Gastric Cancer Cells (AGS) Show a Significant Higher Tendency to Proliferation, Inflammation and Cannabinoid Receptor 1 Expression
Sahar Sedighzadeh, Hamid Galehdari, Mohammad Reza Tabandeh et al. (5 authors)
Jentashapir Journal of Cellular and Molecular Biology
Open Access
Published: Dec 2020
885 days before retraction
Curcuma oil ameliorates benign prostatic hyperplasia through suppression of the nuclear factor-kappa B signaling pathway in rats
Shanshan Wang, Yun Li, Wenzhi Li et al. (9 authors)
Journal of Ethnopharmacology
Open Access
Published: Dec 2020
23 citations
23 citations
897 days before retraction
Immunomodulatory effect of diallyl sulfide on experimentally-induced benign prostate hyperplasia via the suppression of CD4+T/IL-17 and TGF-β1/ERK pathways
Eman M. Elbaz, Hebat Allah A. Amin, Ahmed S. Kamel et al. (5 authors)
Inflammopharmacology
Published: Aug 2020
15 citations
15 citations
1024 days before retraction
Inhibitory Effects of Ginger (Zingiber officinale Roscoe) Ethanol Extract on Benign Prostatic Hyperplasia
Su Joung Kim, Jeong Yoon Lee, Jeong-Sun Ju et al. (4 authors)
Journal of the Korean Society of Food Science and Nutrition
Published: May 2020
2 citations
2 citations
1097 days before retraction
Detection of Prostatic Inflammation From Peripheral Lymphocyte Count and Free/Total PSA Ratio in Men With LUTS/BPH
Xinyang Liao, Zhuang Tang, Jianzhong Ai et al. (11 authors)
Frontiers in Pharmacology
Open Access
Published: Apr 2020
11 citations
11 citations
1128 days before retraction
Asteris Radix et Rhizoma suppresses testosterone-induced benign prostatic hyperplasia in rats by regulating apoptosis and inflammation
Jinhyung Rho, Chang‐Seob Seo, Hee-Seon Park et al. (9 authors)
Journal of Ethnopharmacology
Published: Mar 2020
30 citations
30 citations
1168 days before retraction
An overview of lipoxygenase inhibitors with approach of in vivo studies
Ala Orafaie, Mina Mousavian, Hossein M. Orafai et al. (4 authors)
Prostaglandins & Other Lipid Mediators
Published: Jan 2020
30 citations
30 citations
1234 days before retraction
Modulatory Effect of Silymarin on Apoptosis in Testosterone -Induced Benign Prostatic Hyperplasia in Rats
Nahla E. El‐Ashmawy, Eman G. Khedr, Hoda A. El‐Bahrawy et al. (4 authors)
Pathology & Oncology Research
Published: Jan 2020
12 citations
12 citations
1245 days before retraction
Identification of Peracetylated Quercetin as a Selective 12-Lipoxygenase Pathway Inhibitor in Human Platelets
Marco S. Doucet, Jean‐Luc Jougleux, Samuel Poirier et al. (9 authors)
Molecular Pharmacology
Open Access
Published: Nov 2018
13 citations
13 citations
1668 days before retraction
Flavocoxid attenuates airway inflammation in ovalbumin-induced mouse asthma model
Rania R. Abdеlaziz, Mohammed Kh. ElMahdy, Ghada M. Suddеk
Chemico-Biological Interactions
Published: Jul 2018
28 citations
28 citations
1796 days before retraction
Safer anti-inflammatory therapy through dual COX-2/5-LOX inhibitors: A structure-based approach
Jaismy Jacob P, S. L. Manju, K. R. Ethiraj et al. (4 authors)
European Journal of Pharmaceutical Sciences
Published: Jun 2018
155 citations
155 citations
1823 days before retraction
Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH)
Irene Paterniti, Michela Campolo, Marika Cordaro et al. (7 authors)
Inflammation Research
Published: Apr 2018
26 citations
26 citations
1869 days before retraction
Prostatic inflammation: a potential treatment target for male LUTS due to benign prostatic obstruction
Michael Samarinas, Mauro Gacci, Alexandre de la Taille et al. (4 authors)
Prostate Cancer and Prostatic Diseases
Published: Apr 2018
18 citations
18 citations
1870 days before retraction
Effects of phenidone (DuCLOX-2/5 inhibitor) against N -methyl- N -nitrosourea induced mammary gland carcinoma in albino rats
Swetlana Gautam, Soniya Rani, Sara A. Aldossary et al. (6 authors)
Toxicology and Applied Pharmacology
Published: Apr 2018
8 citations
8 citations
1871 days before retraction
Anti-Inflammatory and Antioxidant Effects of Kelong-Capsule on Testosterone-Induced Benign Prostatic Hyperplasia in Rats
Ling Zhang, Xinrong Fan, Hui Xie et al. (7 authors)
Evidence-based Complementary and Alternative Medicine
Open Access
Published: Jan 2018
15 citations
15 citations
1978 days before retraction
Flavocoxid, a Natural Antioxidant, Protects Mouse Kidney from Cadmium‐Induced Toxicity
Antonio Micali, Giovanni Pallio, Natasha Irrera et al. (15 authors)
Oxidative Medicine and Cellular Longevity
Open Access
Published: Jan 2018
35 citations
35 citations
1978 days before retraction
Pathologic Triggers Related to LUTS and BPH
Vincenzo Mirone, Roberto La Rocca, Marco Franco et al. (4 authors)
Elsevier eBooks
Published: Jan 2018
4 citations
4 citations
1978 days before retraction
Iodine prevents the increase of testosterone-induced oxidative stress in a model of rat prostatic hyperplasia
Michelle Quintero-García, Evangelina Delgado-González, Ana A. Sánchez-Tusié et al. (6 authors)
Free Radical Biology and Medicine
Published: Dec 2017
25 citations
25 citations
1995 days before retraction
Attenuation of Bleomycin-induced pulmonary fibrosis in rats by flavocoxid treatment
Marwa S. Zaghloul, Ramy A. Abdelsalam, Eman Said et al. (5 authors)
Egyptian Journal of Basic and Applied Sciences
Open Access
Published: Nov 2017
23 citations
23 citations
2038 days before retraction
Inhibitory Effect of Thymoquinone on Testosterone‐Induced Benign Prostatic Hyperplasia in Wistar Rats
Bahaa Al‐Trad, Mazhar Salim Al Zoubi, Janti Qar et al. (9 authors)
Phytotherapy Research
Published: Sep 2017
22 citations
22 citations
2073 days before retraction
Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia
Marika Cordaro, Daniela Impellizzeri, Rosalba Siracusa et al. (9 authors)
Toxicology and Applied Pharmacology
Published: Jun 2017
49 citations
49 citations
2182 days before retraction
Management of Benign Prostatic Hyperplasia: Could Dietary Polyphenols Be an Alternative to Existing Therapies?
Chinedum Eleazu, Kate Eleazu, Winner O. Kalu
Frontiers in Pharmacology
Open Access
Published: Apr 2017
47 citations
47 citations
2226 days before retraction
In vitro antiinflammatory and antioxidant potential of root extracts from Ranunculaceae species
Malik Jan, Jan Tauchen, Přemysl Landa et al. (8 authors)
South African Journal of Botany
Open Access
Published: Jan 2017
20 citations
20 citations
2334 days before retraction
New Hydroxycinnamic Acid Esters as Novel 5-Lipoxygenase Inhibitors That Affect Leukotriene Biosynthesis
Luc H. Boudreau, Grégoire Lassalle-Claux, Marc Cormier et al. (7 authors)
Mediators of Inflammation
Open Access
Published: Jan 2017
18 citations
18 citations
2343 days before retraction
Nonsteroidal Anti‐Inflammatory Therapy: A Journey Toward Safety
Catarina Pereira‐Leite, Cláudia Nunes, Sarah K. Jamal et al. (5 authors)
Medicinal Research Reviews
Published: Dec 2016
99 citations
99 citations
2353 days before retraction
Chemical characterization, anti-benign prostatic hyperplasia effect and subchronic toxicity study of total flavonoid extract of Pteris multifida
Guangcheng Dai, Bin Hu, Wenfang Zhang et al. (9 authors)
Food and Chemical Toxicology
Published: Nov 2016
15 citations
15 citations
2393 days before retraction
Inflammatory mediators in the development and progression of benign prostatic hyperplasia
Cosimo De Nunzio, Fabrizio Presicce, Andrea Tubaro
Nature Reviews Urology
Published: Sep 2016
194 citations
194 citations
2436 days before retraction
New medical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia and future perspectives
Simone Albisinni, Ibrahim Biaou, Quentin Marcelis et al. (6 authors)
BMC Urology
Open Access
Published: Sep 2016
22 citations
22 citations
2452 days before retraction
Withania coagulans Extract Induces Cell Apoptosis and Inhibits COX-2 Expression in a Rat Model of Benign Prostatic Hyperplasia
Maryam Sarbishegi, Ozra Khajavi, Mohammad Reza Arab
Nephro-Urology Monthly
Open Access
Published: Aug 2016
9 citations
9 citations
2473 days before retraction
Quick Stats
Total Citations:
69
Years Since Retraction:
2.5 years
Open Access:
Yes
Last Checked:
Jul 24, 2025