Retraction

mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation

Paper Information

Record ID:
45088
Author(s):
Jong Seok Moon
Shu Hisata
Mi Ae Park
Gina M DeNicola
Stefan W Ryter
Kiichi Nakahira
Augustine M K Choi
Journal:
Cell Reports ( Elsevier - Cell Press )
Publication Date:
June 25, 2015
Retraction Date:
June 06, 2023 (2.5 years years ago)
Subjects:
Broad Categories:
Genetics Biology Biochemistry
Institutions:
Country:
🇺🇸 United States
Article Type:
Research Article
Publisher:
Elsevier - Cell Press
Open Access:
Yes
DOI:
10.1016/j.celrep.2015.05.046
PubMed ID:
26119735
Retraction PubMed ID:
37285264

Retraction Details

Retraction Reasons:
Nature of Retraction:

Retraction

Retraction Notice:
10.1016/j.celrep.2023.112639

Citations (358)

358
Total Citations
46
Post-Retraction
(12.8%)
311
Pre-Retraction
0
Same Day
Post-Retraction Citation Analysis
0 Within 30 days
30 Within 1 year
0 After 2+ years
728 Days since retraction (latest)
mTORC1‐GLUT1‐mediated glucose metabolism drives hyperactivation of B cells in primary Sjogren's syndrome
Xuan Luo, Xunyao Wu, Anqi Wang et al. (16 authors)
Immunology
Published: Sep 2022
8 citations
253 days before retraction
How location and cellular signaling combine to activate the NLRP3 inflammasome
Anil Akbal, Alesja Dernst, Marta Lovotti et al. (6 authors)
Cellular and Molecular Immunology Open Access
Published: Sep 2022
145 citations
259 days before retraction
Immunometabolism Dysfunction in the Pathophysiology and Treatment of Rheumatoid Arthritis
Maryam Masoumi, Nader Hashemi, Fatemeh Moadab et al. (9 authors)
Current Medicinal Chemistry
Published: Sep 2022
7 citations
270 days before retraction
Role of pyroptosis in inflammation and cancer
Wei Xiang, Feng Xie, Xiaoxue Zhou et al. (10 authors)
Cellular and Molecular Immunology Open Access
Published: Aug 2022
451 citations
295 days before retraction
General and Emerging Concepts of Immunity
Salvador Iborra, Andrés Hidalgo
Elsevier eBooks
Published: Aug 2022
297 days before retraction
NF-κB: blending metabolism, immunity, and inflammation
Daria Capece, Daniela Verzella, Irene Flati et al. (6 authors)
Trends in Immunology Open Access
Published: Aug 2022
327 citations
299 days before retraction
Location matters: hexokinase 1 in glucose metabolism and inflammation
Sivaraj Mohana Sundaram, Luke A Doughty, Michael W. Sereda
Trends in Endocrinology and Metabolism
Published: Aug 2022
10 citations
302 days before retraction
Glycolysis and the Pentose Phosphate Pathway Promote LPS-Induced NOX2 Oxidase- and IFN-β-Dependent Inflammation in Macrophages
Jonathan R. Erlich, Eunice E. To, Raymond Luong et al. (14 authors)
Antioxidants Open Access
Published: Jul 2022
30 citations
312 days before retraction
Role of glycolysis in the development of atherosclerosis
Lanfang Li, Min Wang, Qiuxiao Ma et al. (5 authors)
AJP Cell Physiology
Published: Jul 2022
38 citations
316 days before retraction
Biology of macrophage fate decision: Implication in inflammatory disorders
Sarika Yadav, Ashish Dwivedi, Anurag Tripathi
Cell Biology International
Published: Jul 2022
19 citations
325 days before retraction
RNA helicase DEAD‐box protein 5 alleviates nonalcoholic steatohepatitis progression via tethering TSC complex and suppressing mTORC1 signaling
Yanqiu Zhang, Shengtao Ye, Wei-Jia Lu et al. (10 authors)
Hepatology
Published: Jul 2022
24 citations
334 days before retraction
Reprogramming Macrophage Metabolism and its Effect on NLRP3 Inflammasome Activation in Sepsis
Ruiheng Luo, Xizhe Li, Dan Wang
Frontiers in Molecular Biosciences Open Access
Published: Jun 2022
8 citations
342 days before retraction
The Integration of Metabolomics with Other Omics: Insights into Understanding Prostate Cancer
Eleazer P. Resurreccion, Ka-wing Fong
Metabolites Open Access
Published: May 2022
23 citations
375 days before retraction
Pathways Related to NLRP3 Inflammasome Activation Induced by Gold Nanorods
Rob J. Vandebriel, Sylvie Rémy, Jolanda P. Vermeulen et al. (12 authors)
International Journal of Molecular Sciences Open Access
Published: May 2022
5 citations
382 days before retraction
A potent PGK1 antagonist reveals PGK1 regulates the production of IL-1β and IL-6
Liping Liao, Wenzhen Dang, Tingting Lin et al. (20 authors)
Acta Pharmaceutica Sinica B Open Access
Published: May 2022
24 citations
388 days before retraction
Reticulon-1A mediates diabetic kidney disease progression through endoplasmic reticulum-mitochondrial contacts in tubular epithelial cells
Yifan Xie, E Jing, Hong Cai et al. (11 authors)
Kidney International Open Access
Published: Apr 2022
50 citations
409 days before retraction
Neuroinflammation, Sleep, and Circadian Rhythms
Mark R. Zielinski, Allison Gibbons
Frontiers in Cellular and Infection Microbiology Open Access
Published: Mar 2022
130 citations
441 days before retraction
Hexokinase 1 cellular localization regulates the metabolic fate of glucose
Adam De Jesus, Farnaz Keyhani-Nejad, Carolina M. Pusec et al. (21 authors)
Molecular Cell Open Access
Published: Mar 2022
109 citations
445 days before retraction
Macrophage-targeted shikonin-loaded nanogels for modulation of inflammasome activation
Matias Cardoso, Vítor M. Gaspar, Carolina Ferreira et al. (6 authors)
Nanomedicine Nanotechnology Biology and Medicine
Published: Mar 2022
10 citations
449 days before retraction
Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia
Erika Sugisawa, Takeshi Kondo, Yutaro Kumagai et al. (13 authors)
Cell Reports Open Access
Published: Mar 2022
13 citations
462 days before retraction
Neutral ceramidase-dependent regulation of macrophage metabolism directs intestinal immune homeostasis and controls enteric infection
Rui Sun, Xuemei Gu, Chao Lei et al. (12 authors)
Cell Reports Open Access
Published: Mar 2022
16 citations
462 days before retraction
Signal Transduction during Metabolic and Inflammatory Reprogramming in Pulmonary Vascular Remodeling
Marta T. Gomes, Yang Bai, Simone R. Potje et al. (6 authors)
International Journal of Molecular Sciences Open Access
Published: Feb 2022
11 citations
469 days before retraction
Cassiaside C Inhibits M1 Polarization of Macrophages by Downregulating Glycolysis
Ye Jin Kim, Sungwoo Lee, Jonghwa Jin et al. (6 authors)
International Journal of Molecular Sciences Open Access
Published: Feb 2022
18 citations
490 days before retraction
Transcriptomic Profile of Canine DH82 Macrophages Infected by Leishmania infantum Promastigotes with Different Virulence Behavior
Alicia Mas, Abel Martínez‐Rodrigo, Javier Carrión et al. (7 authors)
International Journal of Molecular Sciences Open Access
Published: Jan 2022
4 citations
495 days before retraction
Modulation of Macrophage Immunometabolism: A New Approach to Fight Infections
Thierry Gauthier, Wanjun Chen
Frontiers in Immunology Open Access
Published: Jan 2022
91 citations
496 days before retraction
Acetate Improves the Killing of Streptococcus pneumoniae by Alveolar Macrophages via NLRP3 Inflammasome and Glycolysis-HIF-1α Axis
Marina Machado, Thiago A. Patente, Yves Rouillé et al. (10 authors)
Frontiers in Immunology Open Access
Published: Jan 2022
59 citations
502 days before retraction
TFEB signaling attenuates NLRP3‐driven inflammatory responses in severe asthma
Efthymia Theofani, Maria Semitekolou, Κonstantinos Samitas et al. (14 authors)
Allergy
Published: Jan 2022
34 citations
505 days before retraction
Cytoplasmic zinc promotes IL-1β production by monocytes and macrophages through mTORC1-induced glycolysis in rheumatoid arthritis
Bonah Kim, Hee Young Kim, Bo Ruem Yoon et al. (11 authors)
Science Signaling
Published: Jan 2022
34 citations
511 days before retraction
The Influence of Mitochondrial-DNA-Driven Inflammation Pathways on Macrophage Polarization: A New Perspective for Targeted Immunometabolic Therapy in Cerebral Ischemia-Reperfusion Injury
Sihang Yu, Jiaying Fu, Jian Wang et al. (8 authors)
International Journal of Molecular Sciences Open Access
Published: Dec 2021
16 citations
530 days before retraction
Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice
Anna Isaacs‐Ten, Mar Moreno‐Gonzalez, Caitlin Bone et al. (10 authors)
Cellular and Molecular Gastroenterology and Hepatology Open Access
Published: Dec 2021
18 citations
531 days before retraction
Interactions between NLRP3 inflammasome and glycolysis in macrophages: New insights into chronic inflammation pathogenesis
Qun Yu, Maojuan Guo, Wenyun Zeng et al. (9 authors)
Immunity Inflammation and Disease Open Access
Published: Dec 2021
24 citations
540 days before retraction
The Triangle Relationship Between Long Noncoding RNA, RIG-I-like Receptor Signaling Pathway, and Glycolysis
Zhihua Ren, Yueru Yu, Chaoxi Chen et al. (8 authors)
Frontiers in Microbiology Open Access
Published: Nov 2021
20 citations
553 days before retraction
ALDOA maintains NLRP3 inflammasome activation by controlling AMPK activation
Dongsheng Bai, Jiaying Du, Xiumin Bu et al. (8 authors)
Autophagy Open Access
Published: Nov 2021
49 citations
558 days before retraction
The Basally Expressed p53-Mediated Homeostatic Function
Isha Nagpal, Zhi-Min Yuan
Frontiers in Cell and Developmental Biology Open Access
Published: Nov 2021
26 citations
560 days before retraction
Pathogenic Mechanisms Underlying Idiopathic Pulmonary Fibrosis
B.J. Moss, Stefan W. Ryter, Iván O. Rosas
Annual Review of Pathology Mechanisms of Disease
Published: Nov 2021
481 citations
560 days before retraction
Pyruvate kinase M2 (PKM2) interacts with activating transcription factor 2 (ATF2) to bridge glycolysis and pyroptosis in microglia
Mengmeng Li, Hongjian Lu, Xueyan Wang et al. (11 authors)
Molecular Immunology
Published: Nov 2021
36 citations
566 days before retraction
Impact of intracellular innate immune receptors on immunometabolism
Wei-Chun Chou, Elena Rampanelli, Xin Li et al. (4 authors)
Cellular and Molecular Immunology Open Access
Published: Oct 2021
120 citations
589 days before retraction
Metabolic Profile of Innate Immune Cells
Ana Campos Codo, Letícia de Aquino Penteado, Alexandra Ivo de Medeiros et al. (4 authors)
Springer eBooks
Published: Oct 2021
593 days before retraction
Signaling by the inhibitory receptor CD200R is rewired by type I interferon
Michiel van der Vlist, M Inês Pascoal Ramos, Lucas L. van den Hoogen et al. (14 authors)
Science Signaling Open Access
Published: Oct 2021
10 citations
602 days before retraction
Attenuating Effect of Chlorella Extract on NLRP3 Inflammasome Activation by Mitochondrial Reactive Oxygen Species
Yuya Nakashima, Kazuhito Gotoh, Soichi Mizuguchi et al. (7 authors)
Frontiers in Nutrition Open Access
Published: Oct 2021
8 citations
606 days before retraction
Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
Allison K. Meyers, Zhan Wang, Wenzheng Han et al. (18 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Oct 2021
612 days before retraction
Deficiency of Myeloid Pfkfb3 Protects Mice From Lung Edema and Cardiac Dysfunction in LPS-Induced Endotoxemia
Jiean Xu, Lina Wang, Qiuhua Yang et al. (16 authors)
Frontiers in Cardiovascular Medicine Open Access
Published: Sep 2021
17 citations
615 days before retraction
Loss of mTORC2-induced metabolic reprogramming in monocytes uncouples migration and maturation from production of proinflammatory mediators
Maryam Jangani, Juho Vuononvirta, Lamya Zohair Yamani et al. (8 authors)
Journal of Leukocyte Biology Open Access
Published: Sep 2021
10 citations
615 days before retraction
Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis
Mahmoud E. Youssef, Eslam E. Abd El-Fattah, A. M. Abdelhamid et al. (12 authors)
Frontiers in Pharmacology Open Access
Published: Aug 2021
46 citations
659 days before retraction
NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance
Jingyuan Zhang, Tianming Qiu, Liping Jiang et al. (13 authors)
Ecotoxicology and Environmental Safety Open Access
Published: Aug 2021
14 citations
670 days before retraction
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
Charles L. Evavold, Iva Hafner‐Bratkovič, Pascal Devant et al. (11 authors)
Cell Open Access
Published: Jul 2021
326 citations
685 days before retraction
Metabolic Regulation of Macrophage Activation
Ourania Kolliniati, Eleftheria Ieronymaki, Eleni Vergadi et al. (4 authors)
Journal of Innate Immunity Open Access
Published: Jul 2021
113 citations
697 days before retraction
Glucose Metabolism: The Metabolic Signature of Tumor Associated Macrophage
Qi Zhang, Junli Wang, Dipesh Kumar Yadav et al. (5 authors)
Frontiers in Immunology Open Access
Published: Jun 2021
49 citations
707 days before retraction
The Neurogenic Compound P7C3 Regulates the Aerobic Glycolysis by Targeting Phosphoglycerate Kinase 1 in Glioma
Wenjin Chen, Weiqiang Jia, Cuiying Wu et al. (9 authors)
Frontiers in Oncology Open Access
Published: Jun 2021
11 citations
718 days before retraction
Targeting Glycolysis in Macrophages Confers Protection Against Pancreatic Ductal Adenocarcinoma
Hweixian Leong Penny, Je Lin Sieow, Sin Yee Gun et al. (28 authors)
International Journal of Molecular Sciences Open Access
Published: Jun 2021
26 citations
722 days before retraction
Quick Stats
Total Citations: 358
Years Since Retraction: 2.5 years
Open Access: Yes
Last Checked: Jul 24, 2025
Related Papers
Expression of CD62P and CD154 in peripheral blood of patien…
European Journal of Inflammation • 0 citations
microRNA-29b prevents renal fibrosis by attenuating renal t…
International Urology and Nephrology • 32 citations
lncRNA BZRAP1-AS1 Alleviates Rheumatoid Arthritis by Regula…
Immunity, Inflammation and Disease • 17 citations
LncRNA NEAT1 Targets MiR-125/ADAM9 Mediated NF-κB Pathway i…
Skin Research and Technology • 4 citations
MiR-92b-3p ameliorates inflammation and autophagy by target…
International Immunopharmacology • 24 citations
Actions
More from this journal Similar subjects View Original Paper View Retraction Notice