Retraction
SIRT6 drives epithelial-to-mesenchymal transition and metastasis in non-small cell lung cancer via snail-dependent transrepression of KLF4
Paper Information
Record ID:
46049
Journal:
Publication Date:
December 22, 2018
Retraction Date:
July 15, 2023
(2.4 years years ago)
Subjects:
Institution:
Shanghai Lung Cancer Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, ChinaCountry:
🇨🇳 ChinaArticle Type:
Publisher:
Springer - Biomed Central (BMC)
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (51)
51
Total Citations11
Post-Retraction(21.6%)
40
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
6
Within 1 year
0
After 2+ years
671
Days since retraction (latest)
The HNRNPC/CELF2 signaling pathway drives glycolytic reprogramming and mitochondrial dysfunction in drug-resistant acute myeloid leukemia
Xiang Ma, Haodong Li, Ziqi Zhao et al. (10 authors)
Cell & Bioscience
Open Access
Published: May 2025
671 days after retraction
GNGT1 remodels the tumor microenvironment and promotes immune escape through enhancing tumor stemness and modulating the fibrinogen beta chain-neutrophil extracellular trap signaling axis in lung adenocarcinoma
Linlin Fan, Xiaowei Wang, Xiu‐Mei Zhang et al. (11 authors)
Translational Lung Cancer Research
Open Access
Published: Jan 2025
1 citation
1 citation
536 days after retraction
Deciphering the potential role of post-translational modifications of histones in gastrointestinal cancers: a proteomics-based review with therapeutic challenges and opportunities
Reyhaneh Farrokhi Yekta, Masoumeh Farahani, Mehdi Koushki et al. (4 authors)
Frontiers in Oncology
Open Access
Published: Oct 2024
1 citation
1 citation
464 days after retraction
Deacetylation by SIRT6 increases the stability of GILZ to suppress NSCLC cell migration and invasion
Shiyin Chen, Huaping Yang, Zhenghui Hu et al. (7 authors)
Cellular Signalling
Published: Sep 2024
428 days after retraction
<scp>MitoAMPK</scp> inhibits the Warburg effect by <scp>MZF1</scp>–<scp>SIRT6</scp> with glycosis related genes in <scp>NSCLC</scp>
Shangyu Li, Jinyao He, Lijie Zhang et al. (6 authors)
Journal of Cellular and Molecular Medicine
Open Access
Published: Sep 2024
414 days after retraction
ADP-ribosylation, a multifaceted modification: Functions and mechanisms in aging and aging-related diseases
Wu Hao, Zhao Jialong, Yuan Jiuzhi et al. (6 authors)
Ageing Research Reviews
Open Access
Published: May 2024
5 citations
5 citations
318 days after retraction
Circ-10720 as a ceRNA adsorbs microRNA-1238 and modulates ZEB2 to boost NSCLC development by activating EMT
Wei Zhang, Ping Xiao, Bin Liu et al. (4 authors)
European journal of medical research
Open Access
Published: Apr 2024
1 citation
1 citation
272 days after retraction
Epigenetic regulation in cancer therapy: From mechanisms to clinical advances
Lei Tao, Yue Zhou, Yuan Luo et al. (14 authors)
MedComm – Oncology
Open Access
Published: Jan 2024
26 citations
26 citations
173 days after retraction
Epithelial SIRT6 governs IL-17A pathogenicity and drives allergic airway inflammation and remodeling
Jingyun Quan, Xiaoxia Wen, Guomei Su et al. (20 authors)
Nature Communications
Open Access
Published: Dec 2023
20 citations
20 citations
160 days after retraction
Alterations of histone modifications in cancer
Maha Saber-Ayad, Wafaa S. Ramadan, Raafat El‐Awady
Elsevier eBooks
Published: Oct 2023
3 citations
3 citations
97 days after retraction
SIRT6 pharmacological inhibition delays skin cancer progression in the squamous cell carcinoma
Elena Abbotto, Caterina Miro, Francesco Piacente et al. (15 authors)
Biomedicine & Pharmacotherapy
Open Access
Published: Aug 2023
6 citations
6 citations
37 days after retraction
KLF4 as a Novel Prognostic Biomarker and Its Correlation with Immune Infiltrates in Lung Adenocarcinoma
Jiaxin Shen, Wen-Jia Chen, Jianling Zhu et al. (6 authors)
Research Square (Research Square)
Open Access
Published: Jun 2023
43 days before retraction
Clinical benefit of pembrolizumab in treatment of first line non-small cell lung cancer: a systematic review and meta-analysis of clinical characteristics
Wenjie Liu, Gengwei Huo, Peng Chen
BMC Cancer
Open Access
Published: May 2023
15 citations
15 citations
57 days before retraction
KLF4 transcription factor in tumorigenesis
Zhihong He, Jie He, Keping Xie
Cell Death Discovery
Open Access
Published: Apr 2023
86 citations
86 citations
98 days before retraction
<scp>MARVELD3</scp> inhibits the epithelial‐mesenchymal transition and cell migration by suppressing the Wnt/β‐catenin signaling pathway in <scp>non–small</scp> cell lung cancer cells
Shirong Li, Saiping Qi, Yanmeng Li et al. (7 authors)
Thoracic Cancer
Open Access
Published: Mar 2023
6 citations
6 citations
122 days before retraction
The sirtuin family in health and disease
Qi‐Jun Wu, Tie‐Ning Zhang, Huanhuan Chen et al. (16 authors)
Signal Transduction and Targeted Therapy
Open Access
Published: Dec 2022
459 citations
459 citations
198 days before retraction
Inside the stemness engine: Mechanistic links between deregulated transcription factors and stemness in cancer
Egle-Helene Ervin, Rhiannon French, Chao‐Hui Chang et al. (4 authors)
Seminars in Cancer Biology
Open Access
Published: Nov 2022
32 citations
32 citations
252 days before retraction
The histone deacetylase SIRT6 promotes glycolysis through the HIF-1α/HK2 signaling axis and induces erlotinib resistance in non-small cell lung cancer
Qiai You, Jianmin Wang, Yongxin Yu et al. (11 authors)
APOPTOSIS
Open Access
Published: Aug 2022
16 citations
16 citations
348 days before retraction
Efficacy of Atezolizumab for Advanced Non-Small Cell Lung Cancer Based on Clinical and Molecular Features: A Meta-Analysis
Wenjie Liu, Gengwei Huo, Peng Chen
Frontiers in Immunology
Open Access
Published: Jun 2022
9 citations
9 citations
389 days before retraction
<scp>SIRT6</scp> promotes mitochondrial fission and subsequent cellular invasion in ovarian cancer
Shreya Bandopadhyay, Parash Prasad, Upasana Ray et al. (5 authors)
FEBS Open Bio
Open Access
Published: Jun 2022
23 citations
23 citations
400 days before retraction
Sirtuins and Hypoxia in EMT Control
Michele Aventaggiato, Federica Barreca, Luigi Sansone et al. (7 authors)
Pharmaceuticals
Open Access
Published: Jun 2022
9 citations
9 citations
400 days before retraction
Association of sirtuins (SIRT1-7) with lung and intestinal diseases
Yuhan Chen, Di Zhou, Yuan Feng et al. (7 authors)
Molecular and Cellular Biochemistry
Published: May 2022
12 citations
12 citations
421 days before retraction
SIRT6 Widely Regulates Aging, Immunity, and Cancer
Yunjia Li, Jing Jin, Yi Wang
Frontiers in Oncology
Open Access
Published: Apr 2022
43 citations
43 citations
465 days before retraction
Inhibitors of PD-1 in Non-Small Cell Lung Cancer: A Meta-Analysis of Clinical and Molecular Features
Gengwei Huo, Wenjie Liu, Peng Chen
Frontiers in Immunology
Open Access
Published: Apr 2022
18 citations
18 citations
466 days before retraction
KLF4 Induces Mesenchymal–Epithelial Transition (MET) by Suppressing Multiple EMT-Inducing Transcription Factors
Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Isabelle McMullen et al. (7 authors)
Cancers
Open Access
Published: Oct 2021
29 citations
29 citations
640 days before retraction
Upregulating sirtuin 6 ameliorates glycolysis, EMT and distant metastasis of pancreatic adenocarcinoma with krüppel-like factor 10 deficiency
Yi‐Chih Tsai, Suliang Chen, Shu-Ling Peng et al. (7 authors)
Experimental & Molecular Medicine
Open Access
Published: Oct 2021
13 citations
13 citations
652 days before retraction
RETRACTED ARTICLE: Reduced LINC00467 elevates microRNA-125a-3p to suppress cisplatin resistance in non-small cell lung cancer through inhibiting sirtuin 6 and inactivating the ERK1/2 signaling pathway
Feng Xue, Chuan Yang, Keli Yun et al. (11 authors)
Cell Biology and Toxicology
Open Access
Published: Aug 2021
12 citations
12 citations
684 days before retraction
KLF4 induces Mesenchymal - Epithelial Transition (MET) by suppressing multiple EMT-inducing transcription factors
Ayalur Raghu Subbalakshmi, Sarthak Sahoo, Isabelle McMullen et al. (7 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Aug 2021
5 citations
5 citations
687 days before retraction
ZIP4 promotes non-small cell lung cancer metastasis by activating snail-N-cadherin signaling axis
Yuanyuan Jiang, Hanxiang Zhan, Yuqing Zhang et al. (12 authors)
Cancer Letters
Published: Aug 2021
20 citations
20 citations
690 days before retraction
RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein
Chuanying Zhu, Keke Li, Mawei Jiang et al. (4 authors)
Acta Neuropathologica Communications
Open Access
Published: Jul 2021
14 citations
14 citations
740 days before retraction
Current research advances in microRNA-mediated regulation of Krüppel-like factor 4 in cancer: a narrative review
Xi Yang, Cheng Chen, Li Li et al. (6 authors)
Annals of Translational Medicine
Open Access
Published: Jun 2021
4 citations
4 citations
774 days before retraction
Abnormal spindle-like microcephaly-associated protein enhances cell invasion through Wnt/β-catenin-dependent regulation of epithelial-mesenchymal transition in non-small cell lung cancer cells
Chunwei Xia, Xiaofeng Xu, Yiyan Ding et al. (6 authors)
Journal of Thoracic Disease
Open Access
Published: Apr 2021
8 citations
8 citations
835 days before retraction
circUBAP2 exacerbates malignant capabilities of NSCLC by targeting KLF4 through miR-3182 modulation
Guanying Zheng, Jianyuan Huang, Wenshu Chen et al. (6 authors)
Aging
Open Access
Published: Mar 2021
15 citations
15 citations
848 days before retraction
HOXA10 promotion of HDAC1 underpins the development of lung adenocarcinoma through the DNMT1-KLF4 axis
Tiangang Ma, Bingdi Yan, Yanbing Hu et al. (4 authors)
Journal of Experimental & Clinical Cancer Research
Open Access
Published: Feb 2021
15 citations
15 citations
878 days before retraction
FOXO3a Protects against Kidney Injury in Type II Diabetic Nephropathy by Promoting Sirt6 Expression and Inhibiting Smad3 Acetylation
Xiaowei Wang, Tingting Ji, M Kellis et al. (5 authors)
Oxidative Medicine and Cellular Longevity
Open Access
Published: Jan 2021
18 citations
18 citations
925 days before retraction
SIRT6 inhibits metastasis by suppressing SNAIL expression in nasopharyngeal carcinoma cells.
Feng Chen, Xiaofeng Ma, Yongze Liu et al. (6 authors)
Unknown Journal
Published: Jan 2021
6 citations
6 citations
925 days before retraction
Dual role of sirtuins in cancer
Margalida Torrens‐Mas, Pilar Roca
Elsevier eBooks
Published: Jan 2021
2 citations
2 citations
925 days before retraction
CRISPR-cas9 genome editing delivery systems for targeted cancer therapy
Asma Ghaemi, Elnaz Bagheri, Khalil Abnous et al. (6 authors)
Life Sciences
Published: Dec 2020
41 citations
41 citations
928 days before retraction
Emerging roles of SIRT6 in human diseases and its modulators
Gang Liu, Haiying Chen, Hua Liu et al. (5 authors)
Medicinal Research Reviews
Open Access
Published: Dec 2020
122 citations
122 citations
941 days before retraction
Screening of Potential Biomarkers for Gastric Cancer with Diagnostic Value Using Label-Free Global Proteome Analysis
Yongxi Song, Jun Wang, Jingxu Sun et al. (9 authors)
Genomics Proteomics & Bioinformatics
Open Access
Published: Dec 2020
28 citations
28 citations
956 days before retraction
Recent Discoveries on the Involvement of Krüppel-Like Factor 4 in the Most Common Cancer Types
Agnieszka Taracha-Wiśniewska, Grzegorz Kotarba, Sebastian Dworkin et al. (4 authors)
International Journal of Molecular Sciences
Open Access
Published: Nov 2020
32 citations
32 citations
965 days before retraction
Inhibition of SIRT6 potentiates the anti-tumor effect of doxorubicin through suppression of the DNA damage repair pathway in osteosarcoma
Zhongkai Zhang, Sang Hoon Ha, Young Jae Moon et al. (14 authors)
Journal of Experimental & Clinical Cancer Research
Open Access
Published: Nov 2020
23 citations
23 citations
970 days before retraction
Paper citing Combining PARP-1 Inhibition and Radiation in Ewing...
Unknown Authors
Unknown Journal
Published: Nov 2020
970 days before retraction
Antirrhinum majus L. flower extract inhibits cell growth and metastatic properties in human colon and lung cancer cell lines
Jina Seo, Jungjae Lee, Hyi Young Yang et al. (4 authors)
Food Science & Nutrition
Open Access
Published: Oct 2020
13 citations
13 citations
1017 days before retraction
Recent advances and challenges of immune checkpoint inhibitors in immunotherapy of non-small cell lung cancer
Zhuzhu Wu, Shuai Man, Rui Sun et al. (6 authors)
International Immunopharmacology
Published: May 2020
32 citations
32 citations
1149 days before retraction
Lung CSC‐derived exosomal miR‐210‐3p contributes to a pro‐metastatic phenotype in lung cancer by targeting FGFRL1
Li Wang, Jun He, Haoyue Hu et al. (7 authors)
Journal of Cellular and Molecular Medicine
Open Access
Published: May 2020
84 citations
84 citations
1159 days before retraction
Screening of Potential Biomarkers for Gastric Cancer with Diagnostic Value Using Label-free Global Proteome Analysis
Yongxi Song, Jun Wang, Jingxu Sun et al. (9 authors)
medRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Mar 2020
2 citations
2 citations
1222 days before retraction
Upregulated circRNA ARHGAP10 Predicts an Unfavorable Prognosis in NSCLC through Regulation of the miR-150-5p/GLUT-1 Axis
Mingming Jin, Chunzi Shi, Chen Yang et al. (5 authors)
Molecular Therapy — Nucleic Acids
Open Access
Published: Aug 2019
74 citations
74 citations
1423 days before retraction
Role of CircRNAs_100395 in Proliferation and Metastases of Liver Cancer
Qiaming Chen, Zhian Chen, Sai Cao et al. (10 authors)
Medical Science Monitor
Open Access
Published: Aug 2019
27 citations
27 citations
1428 days before retraction
Interleukin‐8/β‐catenin mediates epithelial–mesenchymal transition in ameloblastoma
Jie Zhang, Yanhui Wang, Cunhui Fan et al. (7 authors)
Oral Diseases
Published: Aug 2019
19 citations
19 citations
1436 days before retraction
Quick Stats
Total Citations:
51
Years Since Retraction:
2.4 years
Open Access:
Yes
Last Checked:
Jul 24, 2025