Retraction
Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model
Paper Information
Record ID:
47930
Author(s):
Publication Date:
February 13, 2013
Retraction Date:
October 09, 2023
(2.1 years years ago)
Subjects:
Institutions:
Country:
🇨🇳 ChinaArticle Type:
Publisher:
PLoS
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1371/journal.pone.0292822Citations (47)
47
Total Citations0
Post-Retraction46
Pre-Retraction1
Same DayRetraction: Silencing of APE1 Enhances Sensitivity of Human Hepatocellular Carcinoma Cells to Radiotherapy In Vitro and in a Xenograft Model
Unknown Authors
PLoS ONE
Open Access
Published: Oct 2023
Same day as retraction
Advances in radiotherapy and immunity in hepatocellular carcinoma
Yuhan Yang, Liting Xiong, Mengyuan Li et al. (6 authors)
Journal of Translational Medicine
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Published: Aug 2023
40 citations
40 citations
66 days before retraction
Hydrogen peroxide activates APE1/Ref-1 via NF-κB and Parkin: a role in liver cancer resistance to oxidative stress
Ferbian Milas Siswanto, Kenta Okukawa, Akiyoshi Tamura et al. (5 authors)
Free Radical Research
Published: Mar 2023
5 citations
5 citations
219 days before retraction
Cancer Stem Cell and Hepatic Stellate Cells in Hepatocellular Carcinoma
Adriana G. Quiroz-Reyes, Sonia Amelia Lozano Sepúlveda, Natalia Martínez-Acuña et al. (8 authors)
Technology in Cancer Research & Treatment
Open Access
Published: Jan 2023
16 citations
16 citations
281 days before retraction
Impact of <scp>DNA</scp> damage response defects in cancer cells on response to immunotherapy and radiotherapy
Daniel Czajkowski, Radosław Szmyd, Harriet E. Gee
Journal of Medical Imaging and Radiation Oncology
Open Access
Published: Apr 2022
13 citations
13 citations
534 days before retraction
Clinical and Preclinical Outcomes of Combining Targeted Therapy With Radiotherapy
May Elbanna, Nayela N. Chowdhury, Ryan Rhome et al. (4 authors)
Frontiers in Oncology
Open Access
Published: Oct 2021
26 citations
26 citations
721 days before retraction
High nuclear expression of APE1 correlates with unfavorable prognosis and promotes tumor growth in hepatocellular carcinoma
Xiaohua Lü, Hui Zhao, Hongxin Yuan et al. (5 authors)
Journal of Molecular Histology
Published: Jan 2021
15 citations
15 citations
1008 days before retraction
Apurinic/apyrimidinic endonuclease 1/reduction-oxidation effector factor-1 (APE1) regulates the expression of NLR family pyrin domain containing 3 (NLRP3) inflammasome through modulating transcription factor NF-κB and promoting the secretion of inflammatory mediators in macrophages
Zheng Tang, Ying Wang, Yue Wan et al. (9 authors)
Annals of Translational Medicine
Open Access
Published: Jan 2021
14 citations
14 citations
1011 days before retraction
Targeting NPM1 in irradiated cells inhibits NPM1 binding to RAD51, RAD51 foci formation and radiosensitizes NSCLC
Geri Traver, Konjeti R. Sekhar, Peter A. Crooks et al. (5 authors)
Cancer Letters
Open Access
Published: Dec 2020
13 citations
13 citations
1022 days before retraction
Mitochondrial apurinic/apyrimidinic endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma
Veronica Bazzani, Arianna Barchiesi, Dorota Radecka et al. (8 authors)
BMC Cancer
Open Access
Published: Oct 2020
20 citations
20 citations
1097 days before retraction
Hydrogen peroxide and Helicobacter pylori extract treatment combined with APE1 knockdown induce DNA damage, G2/M arrest and cell death in gastric cancer cell line
Fernanda S. Manoel-Caetano, Ana Flávia Teixeira Rossi, Marcelo Lima Ribeiro et al. (6 authors)
DNA repair
Published: Sep 2020
6 citations
6 citations
1106 days before retraction
Mitochondrial Apurinic/Apyrimidinic Endonuclease 1 enhances mtDNA repair contributing to cell proliferation and mitochondrial integrity in early stages of hepatocellular carcinoma
Veronica Bazzani, Arianna Barchiesi, Dorota Radecka et al. (8 authors)
Research Square (Research Square)
Open Access
Published: Aug 2020
1158 days before retraction
Mitochondrial accumulation of Apurinic/Apyrimidinic Endonuclease 1 protein in early stages of hepatocellular carcinoma enhances mtDNA repair rate, contributing to cell proliferation and mitochondrial functionality.
Veronica Bazzani, Arianna Barchiesi, Dorota Radecka et al. (8 authors)
Research Square (Research Square)
Open Access
Published: Jul 2020
1194 days before retraction
Molecular Bases of Drug Resistance in Hepatocellular Carcinoma
José J.G. Marı́n, Rocı́o I.R. Macı́as, María J. Monte et al. (12 authors)
Cancers
Open Access
Published: Jun 2020
160 citations
160 citations
1203 days before retraction
Mitochondrial Accumulation of Apurinic/Apyrimidinic Endonuclease 1 Protein in Early Stages of Hepatocellular Carcinoma Enhances mtDNA Repairing Rate Contributing to Cell Proliferation and Mitochondrial Functionality.
Veronica Bazzani, Arianna Barchiesi, Dorota Radecka et al. (8 authors)
Research Square (Research Square)
Open Access
Published: Apr 2020
1264 days before retraction
Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment
Ganiou Assani, Julien Segbo, Xiaoyan Yu et al. (7 authors)
Asian Pacific Journal of Cancer Prevention
Open Access
Published: Dec 2019
12 citations
12 citations
1408 days before retraction
Tissue specificity of DNA damage response and tumorigenesis
Siman Sun, Michael D. Osterman, Mo Li
Cancer Biology and Medicine
Open Access
Published: Aug 2019
52 citations
52 citations
1530 days before retraction
Knockdown of miR-106a suppresses migration and invasion and enhances radiosensitivity of hepatocellular carcinoma cells by upregulating FBXW7.
Peng Deng, Yuni Wu
PubMed
Published: Jan 2019
14 citations
14 citations
1742 days before retraction
Analysis of Local Control and Pain Control After Spine Stereotactic Radiosurgery Reveals Inferior Outcomes for Hepatocellular Carcinoma Compared With Other Radioresistant Histologies
Heather M. McGee, T.J. Carpenter, Umut Özbek et al. (9 authors)
Practical Radiation Oncology
Published: Dec 2018
15 citations
15 citations
1764 days before retraction
MiR-92b targets p57kip2 to modulate the resistance of hepatocellular carcinoma (HCC) to ionizing radiation (IR) -based radiotherapy
Jianyang Wang, Hong Zhao, Jing Yu et al. (11 authors)
Biomedicine & Pharmacotherapy
Open Access
Published: Dec 2018
28 citations
28 citations
1764 days before retraction
MicroRNA-146a-5p enhances radiosensitivity in hepatocellular carcinoma through replication protein A3-induced activation of the DNA repair pathway
Jing Luo, Zhongzhou Si, Ting Li et al. (8 authors)
AJP Cell Physiology
Open Access
Published: Nov 2018
49 citations
49 citations
1783 days before retraction
The regulatory role of APE1 in epithelial‐to‐mesenchymal transition and in determining EGFR‐TKI responsiveness in non‐small‐cell lung cancer
Xiao Yang, Yu Peng, Xuan Jiang et al. (16 authors)
Cancer Medicine
Open Access
Published: Aug 2018
36 citations
36 citations
1882 days before retraction
Knockdown of SUMO1P3 represses tumor growth and invasion and enhances radiosensitivity in hepatocellular carcinoma
Yan Zhou, Ping He, Xuhua Xie et al. (4 authors)
Molecular and Cellular Biochemistry
Published: Jun 2018
28 citations
28 citations
1942 days before retraction
GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level
Qing Li, Xi Wei, Zhi-Wei Zhou et al. (12 authors)
Cell Death and Disease
Open Access
Published: May 2018
34 citations
34 citations
1979 days before retraction
Resistance a major hindrance to chemotherapy in hepatocellular carcinoma: an insight
K. Lohitesh, Rajdeep Chowdhury, Sudeshna Mukherjee
Cancer Cell International
Open Access
Published: Mar 2018
241 citations
241 citations
2029 days before retraction
APE1 overexpression is associated with poor survival in patients with solid tumors: a meta-analysis
Chunling Yuan, Fan He, Jiazhou Ye et al. (10 authors)
Oncotarget
Open Access
Published: Aug 2017
33 citations
33 citations
2259 days before retraction
Mechanisms of radioresistance in hepatocellular carcinoma
Alba Kihn-Alarcón, Ximing Xu
Oncology and Translational Medicine
Open Access
Published: Aug 2017
5 citations
5 citations
2260 days before retraction
Role of HDM2 Gene in Radio-Sensitivity of Esophageal Cancer Cell Lines to Irradiation
Mohsen Mohammadi, Jalil Pirayesh Islamian, Hadi Karami et al. (6 authors)
International Journal of Cancer Management
Open Access
Published: Jun 2017
3 citations
3 citations
2292 days before retraction
The Relationship Between Single-Nucleotide Polymorphisms, the Expression of DNA Damage Response Genes, and Hepatocellular Carcinoma in a Polish Population
Renata Krupa, Piotr Czarny, Paulina Wigner et al. (8 authors)
DNA and Cell Biology
Published: Jun 2017
24 citations
24 citations
2313 days before retraction
Pharmacogenetics Biomarkers and Their Specific Role in Neoadjuvant Chemoradiotherapy Treatments: An Exploratory Study on Rectal Cancer Patients
Eva Dreussi, Erika Cecchin, Jerry Polesel et al. (15 authors)
International Journal of Molecular Sciences
Open Access
Published: Sep 2016
11 citations
11 citations
2590 days before retraction
Regulation of HIF1α under Hypoxia by APE1/Ref-1 Impacts CA9 Expression: Dual Targeting in Patient-Derived 3D Pancreatic Cancer Models
Derek P. Logsdon, Michelle Grimard, Meihua Luo et al. (15 authors)
Molecular Cancer Therapeutics
Open Access
Published: Aug 2016
103 citations
103 citations
2608 days before retraction
Dovitinib Acts As a Novel Radiosensitizer in Hepatocellular Carcinoma by Targeting SHP-1/STAT3 Signaling
Chao‐Yuan Huang, Wei‐Tien Tai, Szu‐Yuan Wu et al. (10 authors)
International Journal of Radiation Oncology*Biology*Physics
Published: Jan 2016
15 citations
15 citations
2819 days before retraction
DNA Repair Pathways as a Potential Target for Radiosensitization
Mahmoud Toulany
Springer eBooks
Published: Jan 2016
3 citations
3 citations
2838 days before retraction
Transcriptional Up-Regulation of APE1/Ref-1 in Hepatic Tumor: Role in Hepatocytes Resistance to Oxidative Stress and Apoptosis
Vittorio Di Maso, María Gabriela Mediavilla, Carlo Vascotto et al. (9 authors)
PLoS ONE
Open Access
Published: Dec 2015
45 citations
45 citations
2869 days before retraction
APE1/REF-1 down-regulation enhances the cytotoxic effects of temozolomide in a resistant glioblastoma cell line
Ana Paula Montaldi, Paulo R. D. V. Godoy, Elza Tiemi Sakamoto‐Hojo
Mutation Research/Genetic Toxicology and Environmental Mutagenesis
Open Access
Published: Jun 2015
63 citations
63 citations
3047 days before retraction
Small-molecule BH3 mimetic and pan-Bcl-2 inhibitor AT-101 enhances the antitumor efficacy of cisplatin through inhibition of APE1 repair and&nbsp;redox activity in non-small-cell lung cancer
Tao Ren, Jinlu Shan, Mengxia Li et al. (16 authors)
Drug Design Development and Therapy
Open Access
Published: Jun 2015
30 citations
30 citations
3052 days before retraction
Lentiviral-mediated short hairpin RNA silencing of APE1 suppresses hepatocellular carcinoma proliferation and migration: A potential therapeutic target for hepatoma treatment
Zhihua Zheng, Wei Du, Yanju Li et al. (6 authors)
Oncology Reports
Open Access
Published: May 2015
11 citations
11 citations
3071 days before retraction
Combined Therapy for Gastrointestinal Carcinomas: Exploiting Synergies Between Gene Therapy and Classical Chemo-Radiotherapy
Mariana Malvicini, Jorge B. Aquino, Guillermo Mazzolini
Current Gene Therapy
Open Access
Published: Mar 2015
8 citations
8 citations
3136 days before retraction
Predictive SNPs for radiation-induced damage in lung cancer patients with radiotherapy: a potential strategy to individualize treatment
Qian Huang, Fangwei Xie, Xuenong Ouyang
The International Journal of Biological Markers
Published: Nov 2014
14 citations
14 citations
3262 days before retraction
Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1
Dong Wang, Jiang-Dong Sui, Mengxia Li et al. (7 authors)
Drug Design Development and Therapy
Open Access
Published: Nov 2014
8 citations
8 citations
3264 days before retraction
DNA Repair and Redox Activities and Inhibitors of Apurinic/Apyrimidinic Endonuclease 1/Redox Effector Factor 1 (APE1/Ref-1): A Comparative Analysis and Their Scope and Limitations toward Anticancer Drug Development
Gagandeep Kaur, Ravi P. Cholia, Anil K. Mantha et al. (4 authors)
Journal of Medicinal Chemistry
Published: Oct 2014
37 citations
37 citations
3293 days before retraction
APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
Shweta Thakur, Bibekananda Sarkar, Ravi P. Cholia et al. (6 authors)
Experimental & Molecular Medicine
Open Access
Published: Jul 2014
155 citations
155 citations
3370 days before retraction
Identification of a novel potential antitumor activity of gossypol as an APE1/Ref-1 inhibitor
Dong Wang, Mengxia Li, Jiang-Dong Sui et al. (9 authors)
Drug Design Development and Therapy
Open Access
Published: May 2014
29 citations
29 citations
3448 days before retraction
Involvement of DNA Damage Response Pathways in Hepatocellular Carcinoma
Sheau‐Fang Yang, Chien-Wei Chang, Ren‐Jie Wei et al. (6 authors)
BioMed Research International
Open Access
Published: Jan 2014
98 citations
98 citations
3568 days before retraction
Apurinic/apyrimidinic endonuclease 1 induced upregulation of fibroblast growth factor 2 and its receptor 3 induces angiogenesis in human osteosarcoma cells
Tao Ren, Yi Qing, Nan Dai et al. (11 authors)
Cancer Science
Open Access
Published: Dec 2013
32 citations
32 citations
3589 days before retraction
Influência do Gene APE1/REF-1 nas Respostas Celulares das Linhagens de Glioblastoma ao Quimioterápico Temozolomida
Ana Paula de Lima Montaldi
Unknown Journal
Open Access
Published: Sep 2013
3686 days before retraction
Human Apurinic/Apyrimidinic Endonuclease 1
Mengxia Li, David M. Wilson
Antioxidants and Redox Signaling
Open Access
Published: Jul 2013
237 citations
237 citations
3745 days before retraction
Quick Stats
Total Citations:
47
Years Since Retraction:
2.1 years
Open Access:
Yes
Last Checked:
Jul 24, 2025