Retraction
Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer
Paper Information
Record ID:
50215
Author(s):
Journal:
Publication Date:
March 13, 2023
Retraction Date:
December 11, 2023
(1.9 year years ago)
Subjects:
Institutions:
- Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA
- Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA 02115, USA
- Department of Radiation Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA 02215, USA
- Department of Surgical Oncology and Harvard Medical School, Brigham and Women’s Hospital, Boston, MA 02115, USA
- Department of Medicine, Division of Hematology-Oncology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA
- Hale Family Center for Pancreatic Cancer Research, Dana-Farber Cancer Institute, Boston, MA 02215, USA
- Department of Medicine, Division of Gastroenterology, Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA
- Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, MA 02215, USA
Country:
🇺🇸 United StatesArticle Type:
Publisher:
Springer - Nature Publishing Group
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1038/s41467-023-43803-0Additional Notes:
see also: https://pubpeer.com/publications/EB04F1E734D3E88825F3B712FA4F89
Citations (19)
19
Total Citations11
Post-Retraction(57.9%)
8
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
1
Within 30 days
9
Within 1 year
0
After 2+ years
446
Days since retraction (latest)
Cyclin E1 overexpression triggers interferon signaling and is associated with antitumor immunity in breast cancer
Shibo Yu, Chantal Stappenbelt, Mengting Chen et al. (11 authors)
Journal for ImmunoTherapy of Cancer
Open Access
Published: Mar 2025
446 days after retraction
Intrinsic STING of CD8 + T cells regulates self-metabolic reprogramming and memory to exert anti-tumor effects
Qiuli Xu, Xin Hua, Bingbing Li et al. (13 authors)
Cell Communication and Signaling
Open Access
Published: Feb 2025
2 citations
2 citations
436 days after retraction
DNA damage response inhibitors in cancer therapy: lessons from the past, current status and future implications
Yvette Drew, Frank T. Zenke, Nicola J. Curtin
Nature Reviews Drug Discovery
Published: Nov 2024
33 citations
33 citations
337 days after retraction
Pluripotent stem cell-derived CTLs targeting FGFR3-TACC3 fusion gene in osteosarcoma
Haibo Zhan, Jun Xiao, Shoujie Shi et al. (11 authors)
International Immunopharmacology
Published: Sep 2024
1 citation
1 citation
285 days after retraction
The crosstalk between DNA-damage responses and innate immunity
Mei He, Hua Jiang, Shun Li et al. (7 authors)
International Immunopharmacology
Open Access
Published: Jul 2024
13 citations
13 citations
233 days after retraction
HDAC inhibitor regulates the tumor immune microenvironment via pyroptosis in triple negative breast cancer
Xue Yang, Xiaoqing Cui, Ge Wang et al. (8 authors)
Molecular Carcinogenesis
Open Access
Published: Jun 2024
6 citations
6 citations
183 days after retraction
When DNA-damage responses meet innate and adaptive immunity
Jie Tong, Jiangwei Song, Wuchao Zhang et al. (8 authors)
Cellular and Molecular Life Sciences
Open Access
Published: Apr 2024
28 citations
28 citations
128 days after retraction
Gene polymorphisms of molecules of the cGAS-STING signalling pathway are associated with AML in Chinese patients
Yuechan Ma, Dongmei Wang, Lei Feng et al. (11 authors)
Holistic Integrative Oncology
Open Access
Published: Mar 2024
2 citations
2 citations
98 days after retraction
Tumor Exosomal ENPP1 Hydrolyzes cGAMP to Inhibit cGAS‐STING Signaling
Yu An, Jinchao Zhu, Qihui Xie et al. (13 authors)
Advanced Science
Open Access
Published: Mar 2024
22 citations
22 citations
98 days after retraction
A new 4-gene-based prognostic model accurately predicts breast cancer prognosis and immunotherapy response by integrating WGCNA and bioinformatics analysis
Wenlong Chen, Yakun Kang, Wenyi Sheng et al. (7 authors)
Frontiers in Immunology
Open Access
Published: Feb 2024
12 citations
12 citations
53 days after retraction
HDAC Inhibitor Regulates the Tumor Immune Microenvironment via Pyroptosis in Triple Negative Breast Cancer
Xue Yang, Xiaoqing Cui, Ge Wang et al. (8 authors)
Research Square (Research Square)
Open Access
Published: Jan 2024
22 days after retraction
Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities
John J. Krais, David J. Glass, Ilse Chudoba et al. (19 authors)
Nature Communications
Open Access
Published: Nov 2023
13 citations
13 citations
17 days before retraction
CDC7 inhibition induces replication stress-mediated aneuploid cells with an inflammatory phenotype sensitizing tumors to immune checkpoint blockade
Tomoko Morita, Jie Yu, Yukie Kashima et al. (18 authors)
Nature Communications
Open Access
Published: Nov 2023
11 citations
11 citations
23 days before retraction
DNA repair deficiency and the immune microenvironment: A pathways perspective
Yuzhen Zhou, Kent W. Mouw
DNA repair
Open Access
Published: Nov 2023
3 citations
3 citations
28 days before retraction
DTX3L mediated ubiquitination of cGAS suppresses antitumor immunity in pancreatic cancer
Shan Lin
Biochemical and Biophysical Research Communications
Published: Sep 2023
3 citations
3 citations
77 days before retraction
Paper citing Polymerase θ inhibition activates the cGAS-STING p...
Unknown Authors
Unknown Journal
Published: Aug 2023
132 days before retraction
High Expression of MRE11A Is Associated with Shorter Survival and a Higher Risk of Death in CRC Patients
Daniel Azambuja, Helena e Gloria, Gabriel Montenegro et al. (7 authors)
Genes
Open Access
Published: Jun 2023
179 days before retraction
Polymerase θ inhibition steps on the cGAS pedal
Chelsea M. Smith, Gaorav P. Gupta
Journal of Clinical Investigation
Open Access
Published: May 2023
4 citations
4 citations
194 days before retraction
Pancreatic Cancer: BRCA Targeted Therapy and Beyond
Fergus Keane, Catherine O’Connor, Wungki Park et al. (5 authors)
Cancers
Open Access
Published: May 2023
14 citations
14 citations
197 days before retraction
Quick Stats
Total Citations:
19
Years Since Retraction:
1.9 year
Open Access:
Yes
Last Checked:
Jul 24, 2025