Retraction
Shikonin suppresses proliferation and induces apoptosis in endometrioid endometrial cancer cells via modulating miR-106b/PTEN/AKT/mTOR signaling pathway
Paper Information
Record ID:
52376
Author(s):
Journal:
Publication Date:
April 13, 2018
Retraction Date:
February 28, 2024
(1.7 year years ago)
Subjects:
Institutions:
Country:
🇨🇳 ChinaArticle Type:
Publisher:
Portland Press
Open Access:
Yes
DOI:
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1042/BSR-2017-1546_RETAdditional Notes:
see also: https://pubpeer.com/publications/5B4287259F684343E56D10C9E39807
Citations (46)
46
Total Citations5
Post-Retraction(10.9%)
41
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
1
Within 30 days
3
Within 1 year
0
After 2+ years
492
Days since retraction (latest)
Review projecting shikonin as a therapeutic candidate in female carcinomas: a preclinical perspective
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Yufan Zhao, Shimenghui Deng, Danli Cao et al. (9 authors)
Chinese Herbal Medicines
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398 days after retraction
Role of miRNAs in Cervical Cancer
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The Mechanism and Clinical Research Progress of Tcm Treatment of Breast Cancer
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MedScien
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Advances in MiRNAs Involved in Endometrial Carcinoma
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1 citation
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The Anti-tumor Function of Shikonin by Targeting EGFR/AKT/mTOR Signaling in Human Osteosarcoma Cells
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56 days before retraction
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6 citations
134 days before retraction
Shikonin Causes an Apoptotic Effect on Human Kidney Cancer Cells through Ras/MAPK and PI3K/AKT Pathways
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Molecules
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13 citations
13 citations
161 days before retraction
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177 days before retraction
Natural products modulate cell apoptosis: a promising way for treating endometrial cancer
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Medicine in Novel Technology and Devices
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457 days before retraction
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56 citations
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519 days before retraction
Synergistic Antibacterial Activity with Conventional Antibiotics and Mechanism of Action of Shikonin against Methicillin-Resistant Staphylococcus aureus
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28 citations
28 citations
601 days before retraction
Effects of Qingre Huoxue Jiedu Formula on Nerve Growth Factor-Induced Psoriasis
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808 days before retraction
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15 citations
15 citations
810 days before retraction
Shikonin Promotes Apoptosis and Attenuates Migration and Invasion of Human Esophageal Cancer Cells by Inhibiting Tumor Necrosis Factor Receptor-Associated Protein 1 Expression and AKT/mTOR Signaling Pathway
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Evidence-based Complementary and Alternative Medicine
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5 citations
5 citations
837 days before retraction
Shikonin, a naphthalene ingredient: Therapeutic actions, pharmacokinetics, toxicology, clinical trials and pharmaceutical researches
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114 citations
114 citations
856 days before retraction
Scutellarin Inhibits the Growth and EMT of Gastric Cancer Cells through Regulating PTEN/PI3K Pathway
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Biological and Pharmaceutical Bulletin
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Published: May 2021
22 citations
22 citations
1003 days before retraction
Non-Coding RNAs as Prognostic Markers for Endometrial Cancer
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55 citations
55 citations
1076 days before retraction
MicroRNA as Epigenetic Modifiers in Endometrial Cancer: A Systematic Review
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Published: Mar 2021
26 citations
26 citations
1089 days before retraction
Small Non-Coding-RNA in Gynecological Malignancies
Shailendra Kumar Dhar Dwivedi, Geeta Rao, Anindya Dey et al. (6 authors)
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Published: Mar 2021
34 citations
34 citations
1092 days before retraction
Anti-Tumor Mechanisms Associated With Regulation of Non-Coding RNA by Active Ingredients of Chinese Medicine: A Review
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Frontiers in Oncology
Open Access
Published: Feb 2021
12 citations
12 citations
1105 days before retraction
Inhibition of BAG3 enhances the anticancer effect of shikonin in hepatocellular carcinoma.
Jie Lu, Shuang-Yu Liu, Jing Zhang et al. (11 authors)
American Journal of Cancer Research
Published: Jan 2021
10 citations
10 citations
1153 days before retraction
Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer
Yang Chen, Yun Gao, Xiaojiao Yi et al. (6 authors)
Frontiers in Pharmacology
Open Access
Published: Oct 2020
17 citations
17 citations
1224 days before retraction
Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell Lines
Unchalee Thonsri, Wunchana Seubwai, Sakda Waraasawapati et al. (7 authors)
Anticancer Research
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32 citations
32 citations
1275 days before retraction
Anticancer Effects of Fufang Yiliu Yin Formula on Colorectal Cancer Through Modulation of the PI3K/Akt Pathway and BCL-2 Family Proteins
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Frontiers in Cell and Developmental Biology
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14 citations
14 citations
1296 days before retraction
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Guochang Zhang, Nan Zhai, Xiaofen Zhang
BioFactors
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6 citations
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Competitive glucose metabolism as a target to boost bladder cancer immunotherapy
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118 citations
118 citations
1503 days before retraction
Quinolizidine alkaloids derivatives from Sophora alopecuroides Linn: Bioactivities, structure-activity relationships and preliminary molecular mechanisms
Yang Li, Guan Wang, Jie Liu et al. (4 authors)
European Journal of Medicinal Chemistry
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86 citations
86 citations
1528 days before retraction
Shikonin-induced Apoptosis of Colon Cancer Cells Is Reduced by Peroxiredoxin V Expression
Nisansala Chandimali, Hu‐Nan Sun, Ling-Zu Kong et al. (7 authors)
Anticancer Research
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Published: Nov 2019
21 citations
21 citations
1580 days before retraction
Shikonin suppresses progression and epithelial–mesenchymal transition in hepatocellular carcinoma (HCC) cells by modulating miR‐106b/SMAD7/TGF‐β signaling pathway
Xiaojing Li, Xianpeng Zeng
Cell Biology International
Published: Oct 2019
25 citations
25 citations
1596 days before retraction
Shikonin attenuates sympathetic remodeling in chronic heart failure mice via regulating miR-124
Liu Wen-lin, Qiang Liu
Biochemical and Biophysical Research Communications
Published: Oct 2019
16 citations
16 citations
1604 days before retraction
Pharmacological properties and derivatives of shikonin—A review in recent years
Chuanjie Guo, Junlin He, Xiaominting Song et al. (9 authors)
Pharmacological Research
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285 citations
285 citations
1620 days before retraction
ER-mediated anti-tumor effects of shikonin on breast cancer
Yang Yang, Wenya Gao, Shiying Tao et al. (8 authors)
European Journal of Pharmacology
Published: Sep 2019
25 citations
25 citations
1622 days before retraction
Apoptotic Pathway as the Therapeutic Target for Anticancer Traditional Chinese Medicines
Weixiao An, Honglin Lai, Yangyang Zhang et al. (6 authors)
Frontiers in Pharmacology
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Published: Jul 2019
80 citations
80 citations
1692 days before retraction
RETRACTED ARTICLE: Shikonin inhibits proliferation, migration, invasion and promotes apoptosis in NCI-N87 cells via inhibition of PI3K/AKT signal pathway
Liushun Jia, Zhen Zhu, Hongbo Li et al. (4 authors)
Artificial Cells Nanomedicine and Biotechnology
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Published: Jul 2019
25 citations
25 citations
1703 days before retraction
The Use of microRNAs in the Management of Endometrial Cancer: A Meta-Analysis
Romain Delangle, Tiphaine de Foucher, Annette K. Larsen et al. (11 authors)
Cancers
Open Access
Published: Jun 2019
55 citations
55 citations
1718 days before retraction
Shikonin derivatives for cancer prevention and therapy
Joelle C. Boulos, Muhammad Rahama, Mohamed‐Elamir F. Hegazy et al. (4 authors)
Cancer Letters
Published: May 2019
179 citations
179 citations
1741 days before retraction
Bioactive Ingredients in Chinese Herbal Medicines That Target Non-coding RNAs: Promising New Choices for Disease Treatment
Yan Dong, Hengwen Chen, Jialiang Gao et al. (6 authors)
Frontiers in Pharmacology
Open Access
Published: May 2019
54 citations
54 citations
1744 days before retraction
The role of miR-106p-5p in cervical cancer: from expression to molecular mechanism
Yuexiong Yi, Yanyan Liu, Wanrong Wu et al. (5 authors)
Cell Death Discovery
Open Access
Published: Sep 2018
21 citations
21 citations
1987 days before retraction
Downregulation of microRNA‑21 expression inhibits proliferation, and induces G1 arrest and apoptosis via the PTEN/AKT pathway in SKM‑1 cells
Guang Li, Yanping Song, Gangcan Li et al. (9 authors)
Molecular Medicine Reports
Open Access
Published: Jul 2018
30 citations
30 citations
2064 days before retraction
Quick Stats
Total Citations:
46
Years Since Retraction:
1.7 year
Open Access:
Yes
Last Checked:
Jul 24, 2025