Retraction
Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy
Paper Information
Record ID:
53415
Author(s):
Publication Date:
February 03, 2015
Retraction Date:
March 20, 2024
(1.7 year years ago)
Subjects:
Institutions:
- Department of Medical Biophysics, University Health Network, University of Toronto, Toronto, M5G2M9, ON, Canada
- Division of Medical Oncology and Hematology, Princess Margaret Cancer Center and University Health Network, University of Toronto, Toronto, M5G2M9, ON, Canada
- Institute of Medical Science, University Health Network, University of Toronto, Toronto, M5G2M9, ON, Canada
Country:
🇨🇦 CanadaArticle Type:
Publisher:
Springer - Nature Publishing Group
Open Access:
Yes
DOI:
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1038/s41416-024-02660-4Additional Notes:
See also: https://pubpeer.com/publications/9EF728F67F541D99D53BF0F6470582
Citations (54)
54
Total Citations3
Post-Retraction(5.6%)
51
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
3
Within 1 year
0
After 2+ years
270
Days since retraction (latest)
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Pantoprazole enhances osimertinib activity by inhibiting autophagy in NSCLC cells and tumor xenografts
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FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy
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Proton pump inhibitors can reverse the YAP mediated paclitaxel resistance in epithelial ovarian cancer
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Early neutropenia on day 8 treated with adjuvant Docetaxel-based chemotherapy in early breast cancer patients: Putative mechanisms within the neutrophil pool system
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PLoS ONE
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Pantoprazole Affecting Docetaxel Resistance Pathways via Autophagy (PANDORA): Phase II Trial of High Dose Pantoprazole (Autophagy Inhibitor) with Docetaxel in Metastatic Castration-Resistant Prostate Cancer (mCRPC)
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Docetaxel enhances lysosomal function through TFEB activation
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Cell Death and Disease
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The proton pump inhibitor pantoprazole disrupts protein degradation systems and sensitizes cancer cells to death under various stresses
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Cell Death and Disease
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21 citations
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Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity
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41 citations
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2542 days before retraction
Metabolic reprogramming in cancer cells, consequences on pH and tumour progression: Integrated therapeutic perspectives with dietary lipids as adjuvant to anticancer treatment
Jean‐François Dumas, Lucie Brisson, Stéphan Chevalier et al. (8 authors)
Seminars in Cancer Biology
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31 citations
31 citations
2559 days before retraction
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2635 days before retraction
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100 citations
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2727 days before retraction
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2743 days before retraction
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19 citations
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2776 days before retraction
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Qian Tan, Marina Wang, Man Yu et al. (7 authors)
Neoplasia
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99 citations
99 citations
2849 days before retraction
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34 citations
34 citations
2934 days before retraction
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International Journal of Cancer
Open Access
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99 citations
99 citations
2989 days before retraction
Autophagy as a Survival Mechanism for Tumor Cells Exposed to Chemotherapy or Hypoxia, and its Inhibition by Pantoprazole to Improve Outcome of Treatment
Qian Tan
Unknown Journal
Published: Nov 2015
1 citation
1 citation
3062 days before retraction
Influence of the proton pump inhibitor lansoprazole on distribution and activity of doxorubicin in solid tumors
Man Yu, Carol Lee, Marina Wang et al. (4 authors)
Cancer Science
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46 citations
46 citations
3161 days before retraction
Quick Stats
Total Citations:
54
Years Since Retraction:
1.7 year
Open Access:
Yes
Last Checked:
Jul 24, 2025