Retraction
Cancer-Associated PP2A Aα Subunits Induce Functional Haploinsufficiency and Tumorigenicity
Paper Information
Record ID:
53501
Journal:
Publication Date:
September 15, 2005
Retraction Date:
March 15, 2024
(1.7 year years ago)
Subjects:
Country:
🇺🇸 United StatesArticle Type:
Publisher:
American Association for Cancer Research
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1158/0008-5472.CAN-24-0434Additional Notes:
See also: https://pubpeer.com/publications/CF14E205A17927ADE0ACE0F148660E
Citations (163)
163
Total Citations6
Post-Retraction(3.7%)
156
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
1
Within 30 days
5
Within 1 year
0
After 2+ years
469
Days since retraction (latest)
Dual compartment utility of BRET-based biosensors for PPP2R5A/B56α, a cancer-associated B regulatory subunit of PP2A
Hirofumi Yamauchi, Atsuro Oishi, Masahiko Ajiro et al. (21 authors)
BioTechniques
Open Access
Published: Jun 2025
469 days after retraction
BRG1 promotes progression of B-cell acute lymphoblastic leukemia by disrupting PPP2R1A transcription
Qian Kang, Dan Ma, Peng Zhao et al. (15 authors)
Cell Death and Disease
Open Access
Published: Aug 2024
2 citations
2 citations
164 days after retraction
Paradoxical action of PP2A inhibition and its potential for therapeutic sensitization
Yue Jiang, Ying Yuan, Guanglei Qiao et al. (10 authors)
Journal of Cellular Physiology
Open Access
Published: Aug 2024
1 citation
1 citation
154 days after retraction
Urolithin A attenuates hexavalent chromium-induced small intestinal injury by modulating PP2A/Hippo/YAP1 pathway
Ping Guo, Rongfang Yang, Shiyuan Zhong et al. (15 authors)
Journal of Biological Chemistry
Open Access
Published: Aug 2024
1 citation
1 citation
148 days after retraction
PP2A B55α inhibits epithelial-mesenchymal transition via regulation of Slug expression in non-small cell lung cancer
Deepika Singh, Zhaojun Qiu, Jonathan M. Spehar et al. (15 authors)
Cancer Letters
Open Access
Published: Jul 2024
2 citations
2 citations
115 days after retraction
The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism
Michiel Remmerie, Rüveyda Dok, Zhigang Wang et al. (11 authors)
Research Square (Research Square)
Open Access
Published: Apr 2024
28 days after retraction
Retraction: Cancer-Associated PP2A Aα Subunits Induce Functional Haploinsufficiency and Tumorigenicity
Wen Chen, Jason D. Arroyo, Jamie C. Timmons et al. (5 authors)
Cancer Research
Open Access
Published: Mar 2024
Same day as retraction
Correlation analysis of PPP2R1A gene expression and immune infiltration in hepatocellular carcinoma
Xiancong Peng, Qizhi Wang, Hailun Zheng et al. (13 authors)
Research Square (Research Square)
Open Access
Published: Dec 2023
100 days before retraction
Classical swine fever virus NS5A protein activates autophagy via the PP2A-DAPK3-Beclin 1 axis
Jinfu Sun, Haixiao Yu, Yingnan Wang et al. (8 authors)
Journal of Virology
Open Access
Published: Dec 2023
3 citations
3 citations
105 days before retraction
Chemotherapy-induced neuronal DNA damage: an intriguing toolbox to elucidate DNA repair mechanisms in the brain
Aishwarya Babu, Madhusoodanan Urulangodi
Genome Instability & Disease
Published: Nov 2023
1 citation
1 citation
130 days before retraction
Phosphorylation of axin within biomolecular condensates counteracts its tankyrase-mediated degradation
Katharina Klement, Martina K. Brückner, Dominic B. Bernkopf
Journal of Cell Science
Open Access
Published: Sep 2023
8 citations
8 citations
179 days before retraction
PPP2R1A regulates migration persistence through the NHSL1-containing WAVE Shell Complex
Yanan Wang, Giovanni Chiappetta, Raphaël Guérois et al. (14 authors)
Nature Communications
Open Access
Published: Jun 2023
12 citations
12 citations
274 days before retraction
Fam72a functions as a cell-cycle-controlled gene during proliferation and antagonizes apoptosis through reprogramming PP2A substrates
Yuan Fu, Xiaofan Jia, Jinwei Yuan et al. (8 authors)
Developmental Cell
Open Access
Published: Mar 2023
7 citations
7 citations
380 days before retraction
Small-Molecule–Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death
Rita A. Avelar, Amy J. Armstrong, Gracie Carvette et al. (23 authors)
Molecular Cancer Therapeutics
Open Access
Published: Feb 2023
17 citations
17 citations
395 days before retraction
ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response
Amrita Sule, Sarah E. Golding, Syed Farhan Ahmad et al. (11 authors)
Cellular and Molecular Life Sciences
Open Access
Published: Nov 2022
10 citations
10 citations
477 days before retraction
Biased holoenzyme assembly of protein phosphatase 2A (PP2A): From cancer to small molecules
Terrance J. Haanen, Caitlin M. O’Connor, Goutham Narla
Journal of Biological Chemistry
Open Access
Published: Nov 2022
15 citations
15 citations
500 days before retraction
Pleiotropy of PP2A Phosphatases in Cancer with a Focus on Glioblastoma IDH Wildtype
Elham Kashani, Erik Vassella
Cancers
Open Access
Published: Oct 2022
9 citations
9 citations
507 days before retraction
Research progress on the relationship between the TOR signaling pathway regulator, epigenetics, and tumor development
Jiaen Sun, Minglei Yang, Weidi Zhao et al. (9 authors)
Frontiers in Genetics
Open Access
Published: Sep 2022
2 citations
2 citations
539 days before retraction
TurboID Screening of the OmpP2 Protein Reveals Host Proteins Involved in Recognition and Phagocytosis of <i>Glaesserella parasuis</i> by iPAM Cells
Changsheng Jiang, Ningning Ma, Hua Cao et al. (12 authors)
Microbiology Spectrum
Open Access
Published: Sep 2022
10 citations
10 citations
550 days before retraction
Small molecule mediated stabilization of PP2A modulates the Homologous Recombination pathway and potentiates DNA damage-induced cell death
Rita A. Avelar, Amy J. Armstrong, Gracie Carvette et al. (22 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jun 2022
642 days before retraction
PPP2R1A Regulates Migration Persistence through the WAVE Shell Complex
Yanan Wang, Giovanni Chiappetta, Raphaël Guérois et al. (11 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jun 2022
1 citation
1 citation
651 days before retraction
PP2A and cancer epigenetics: a therapeutic opportunity waiting to happen
Samantha L. Tinsley, Brittany L. Allen-Petersen
NAR Cancer
Open Access
Published: Jan 2022
17 citations
17 citations
792 days before retraction
Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma
Caitlin M. O’Connor, Sarah E. Taylor, Kathryn Miller et al. (14 authors)
Cancer Research
Open Access
Published: Dec 2021
10 citations
10 citations
819 days before retraction
ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response
Amrita Sule, Sarah E. Golding, Syed F. Farhan et al. (11 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Aug 2021
1 citation
1 citation
929 days before retraction
Review of PP2A Tumor Biology and Antitumor Effects of PP2A Inhibitor LB100 in the Nervous System
Jean-Paul Bryant, Adam S. Levy, John D. Heiss et al. (4 authors)
Cancers
Open Access
Published: Jun 2021
13 citations
13 citations
998 days before retraction
Review of PP2A Tumor Biology and Anti-Tumor Effects of PP2A Inhibitor LB100 in the Nervous System
Jean-Paul Bryant, Adam S. Levy, John D. Heiss et al. (4 authors)
Unknown Journal
Open Access
Published: May 2021
5 citations
5 citations
1037 days before retraction
Competition between two phosphatases fine-tunes Hedgehog signaling
Min Liu, Aiguo Liu, Jie Wang et al. (7 authors)
The Journal of Cell Biology
Open Access
Published: Dec 2020
8 citations
8 citations
1172 days before retraction
The Greatwall kinase safeguards the genome integrity by affecting the kinome activity in mitosis
Xavier Bisteau, Joann S Lee, Vinayaka Srinivas et al. (16 authors)
Oncogene
Open Access
Published: Sep 2020
14 citations
14 citations
1267 days before retraction
Protective role of anticancer drugs in neurodegenerative disorders: A drug repurposing approach
Dia Advani, Rohan Gupta, Rahul Tripathi et al. (6 authors)
Neurochemistry International
Published: Aug 2020
19 citations
19 citations
1299 days before retraction
Perturbation of Specific Signaling Pathways Is Involved in Initiation of Mouse Liver Fibrosis
Liping Chen, Ping Guo, Wenxue Li et al. (18 authors)
Hepatology
Published: Jul 2020
25 citations
25 citations
1342 days before retraction
Faculty Opinions recommendation of Selective PP2A Enhancement through Biased Heterotrimer Stabilization.
Edward Yu
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
Open Access
Published: May 2020
1414 days before retraction
N-Methyl-D-Aspartate Receptor Hypofunction in Meg-01 Cells Reveals a Role for Intracellular Calcium Homeostasis in Balancing Megakaryocytic-Erythroid Differentiation
James I. Hearn, Taryn N. Green, Martin Chopra et al. (11 authors)
Thrombosis and Haemostasis
Open Access
Published: Apr 2020
13 citations
13 citations
1444 days before retraction
Selective PP2A Enhancement through Biased Heterotrimer Stabilization
Daniel Léonard, Wei Huang, Sudeh Izadmehr et al. (19 authors)
Cell
Open Access
Published: Apr 2020
146 citations
146 citations
1444 days before retraction
AKT Regulates Mitotic Progression of Mammalian Cells by Phosphorylating MASTL, Leading to Protein Phosphatase 2A Inactivation
Irfana Reshi, Misbah Un Nisa, Umer Farooq et al. (9 authors)
Molecular and Cellular Biology
Open Access
Published: Mar 2020
13 citations
13 citations
1473 days before retraction
Phosphoproteome and drug-response effects mediated by the three protein phosphatase 2A inhibitor proteins CIP2A, SET, and PME-1
Otto Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy et al. (20 authors)
Journal of Biological Chemistry
Open Access
Published: Feb 2020
63 citations
63 citations
1487 days before retraction
STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation of human cells
Jong Wook Kim, Christian Berrios, Mi‐Ju Kim et al. (17 authors)
eLife
Open Access
Published: Jan 2020
52 citations
52 citations
1528 days before retraction
Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers
Caroline Farrington, Rui Yuan, Sahar Mazhar et al. (13 authors)
Journal of Biological Chemistry
Open Access
Published: Jan 2020
41 citations
41 citations
1535 days before retraction
Molecular crosstalk between cancer and neurodegenerative diseases
Jiyeon Seo, Mikyoung Park
Cellular and Molecular Life Sciences
Open Access
Published: Dec 2019
85 citations
85 citations
1539 days before retraction
Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers
Caroline Farrington, Rui Yuan, Sahar Mazhar et al. (13 authors)
Journal of Biological Chemistry
Open Access
Published: Dec 2019
37 citations
37 citations
1557 days before retraction
STRIPAK directs PP2A activity toward MAP4K4 to promote oncogenic transformation
Jong Wook Kim, Christian Berrios, Mi‐Ju Kim et al. (18 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Oct 2019
1599 days before retraction
Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors
Caitlin M. O’Connor, Daniel Léonard, Danica Wiredja et al. (19 authors)
Oncogene
Open Access
Published: Sep 2019
36 citations
36 citations
1638 days before retraction
Mission Possible: Advances in MYC Therapeutic Targeting in Cancer
Brittany L. Allen-Petersen, Rosalie C. Sears
BioDrugs
Open Access
Published: Aug 2019
142 citations
142 citations
1682 days before retraction
Interplay between Phosphatases and the Anaphase-Promoting Complex/Cyclosome in Mitosis
Meghna Kataria, Hiroyuki Yamano
Cells
Open Access
Published: Aug 2019
16 citations
16 citations
1687 days before retraction
PP2A: A Promising Biomarker and Therapeutic Target in Endometrial Cancer
Michiel Remmerie, Veerle Janssens
Frontiers in Oncology
Open Access
Published: Jun 2019
53 citations
53 citations
1746 days before retraction
The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis
Sarah E. Taylor, Caitlin M. O’Connor, Zhizhi Wang et al. (20 authors)
Cancer Research
Open Access
Published: May 2019
48 citations
48 citations
1751 days before retraction
De Novo Mutations Affecting the Catalytic Cα Subunit of PP2A, PPP2CA, Cause Syndromic Intellectual Disability Resembling Other PP2A-Related Neurodevelopmental Disorders
Sara Reynhout, Sandra Jansen, Dorien Haesen et al. (37 authors)
The American Journal of Human Genetics
Open Access
Published: Dec 2018
52 citations
52 citations
1905 days before retraction
Protein phosphatases in the regulation of mitosis
Jakob Nilsson
The Journal of Cell Biology
Open Access
Published: Nov 2018
102 citations
102 citations
1946 days before retraction
Regulation of ATM and ATR by SMARCAL1 and BRG1
Ramesh Sethy, Rakesh Radhakrishnan, Ketki Patne et al. (8 authors)
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
Open Access
Published: Oct 2018
21 citations
21 citations
1982 days before retraction
A Quantitative Chemical Proteomic Strategy for Profiling Phosphoprotein Phosphatases from Yeast to Humans
Scott P. Lyons, Nicole P. Jenkins, Isha Nasa et al. (9 authors)
Molecular & Cellular Proteomics
Open Access
Published: Sep 2018
29 citations
29 citations
2004 days before retraction
Distinguishing the progression of an endometrioma: Benign or malignant?
Ercan Baştu, Semen Önder, İrem Demiral et al. (11 authors)
European Journal of Obstetrics & Gynecology and Reproductive Biology
Published: Sep 2018
6 citations
6 citations
2010 days before retraction
Quick Stats
Total Citations:
163
Years Since Retraction:
1.7 year
Open Access:
Yes
Last Checked:
Jul 24, 2025