Retraction
Cancer-Associated PP2A Aα Subunits Induce Functional Haploinsufficiency and Tumorigenicity
Paper Information
Record ID:
53501
Journal:
Publication Date:
September 15, 2005
Retraction Date:
March 15, 2024
(1.7 year years ago)
Subjects:
Country:
🇺🇸 United StatesArticle Type:
Publisher:
American Association for Cancer Research
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.1158/0008-5472.CAN-24-0434Additional Notes:
See also: https://pubpeer.com/publications/CF14E205A17927ADE0ACE0F148660E
Citations (163)
163
Total Citations6
Post-Retraction(3.7%)
156
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
1
Within 30 days
5
Within 1 year
0
After 2+ years
469
Days since retraction (latest)
Targeting PP2A in cancer: Combination therapies
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Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
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Published: Sep 2018
124 citations
124 citations
2022 days before retraction
PP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells
Otto Kauko, Caitlin M. O’Connor, Evgeny Kulesskiy et al. (18 authors)
Science Translational Medicine
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Published: Jul 2018
136 citations
136 citations
2067 days before retraction
Physiologic functions of PP2A: Lessons from genetically modified mice
Sara Reynhout, Veerle Janssens
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Open Access
Published: Jul 2018
119 citations
119 citations
2067 days before retraction
<i>PPP2R1A</i> regulated by PAX3/FOXO1 fusion contributes to the acquisition of aggressive behavior in PAX3/FOXO1-positive alveolar rhabdomyosarcoma
Keisuke Akaike, Yoshiyuki Suehara, Shinji Kohsaka et al. (17 authors)
Oncotarget
Open Access
Published: May 2018
8 citations
8 citations
2128 days before retraction
Protein phosphatase 2A as a new target for downregulating osteoclastogenesis and alleviating titanium particle-induced bone resorption
Liangliang Wang, Xiaobin Guo, Wei Zhou et al. (10 authors)
Acta Biomaterialia
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20 citations
20 citations
2164 days before retraction
<scp>PME</scp>‐1 is regulated by <scp>USP</scp>36 in <scp>ERK</scp> and Akt signaling pathways
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FEBS Letters
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Published: Mar 2018
8 citations
8 citations
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B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies
Gang Xiao, Lai N. Chan, Lars Klemm et al. (20 authors)
Cell
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112 citations
112 citations
2189 days before retraction
Rules for PP2A-controlled phosphosignalling and drug responses
Otto Kauko, Susumu Y. Imanishi, Evgeny Kulesskiy et al. (17 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Feb 2018
11 citations
11 citations
2209 days before retraction
Protein Phosphatase 2A in the Regulation of Wnt Signaling, Stem Cells, and Cancer
Joshua J. Thompson, Christopher S. Williams
Genes
Open Access
Published: Feb 2018
62 citations
62 citations
2209 days before retraction
Non-genomic mechanisms of protein phosphatase 2A (PP2A) regulation in cancer
Otto Kauko, Jukka Westermarck
The International Journal of Biochemistry & Cell Biology
Published: Jan 2018
105 citations
105 citations
2235 days before retraction
Regulation of β-Catenin Phosphorylation by PR55β in Adenoid Cystic Carcinoma
Kana Ishibashi, Kotaro Ishii, Goro Sugiyama et al. (12 authors)
Cancer Genomics & Proteomics
Open Access
Published: Jan 2018
8 citations
8 citations
2264 days before retraction
In vivo pieces of the PP2A onco-puzzle fallen into place
Bob Meeusen, Veerle Janssens
Oncoscience
Open Access
Published: Dec 2017
2 citations
2 citations
2277 days before retraction
Developmental and light regulation of tumor suppressor protein PP2A in the retina
Ammaji Rajala, Yuhong Wang, Steven F. Abcouwer et al. (5 authors)
Oncotarget
Open Access
Published: Dec 2017
7 citations
7 citations
2280 days before retraction
PP2A Inactivation Mediated by <i>PPP2R4</i> Haploinsufficiency Promotes Cancer Development
Ward Sents, Bob Meeusen, Petar Kalev et al. (13 authors)
Cancer Research
Open Access
Published: Oct 2017
40 citations
40 citations
2339 days before retraction
Tumor suppressive protein phosphatases in human cancer: Emerging targets for therapeutic intervention and tumor stratification
Bob Meeusen, Veerle Janssens
The International Journal of Biochemistry & Cell Biology
Published: Oct 2017
92 citations
92 citations
2345 days before retraction
Loss of protein phosphatase 2A regulatory subunit B56δ promotes spontaneous tumorigenesis in vivo
Charlotte Lambrecht, Louis Libbrecht, Xavier Sagaert et al. (10 authors)
Oncogene
Published: Oct 2017
46 citations
46 citations
2356 days before retraction
Functional importance of PP2A regulatory subunit loss in breast cancer
Lauren F. Watt, Nikita Panicker, Abdul Mannan et al. (9 authors)
Breast Cancer Research and Treatment
Published: Jul 2017
24 citations
24 citations
2425 days before retraction
The PP2A-B56 Phosphatase Opposes Cyclin E Autocatalytic Degradation via Site-Specific Dephosphorylation
Ryan J. Davis, Jherek Swanger, Bridget T. Hughes et al. (4 authors)
Molecular and Cellular Biology
Open Access
Published: Jan 2017
14 citations
14 citations
2600 days before retraction
Paper citing Cancer-Associated PP2A Aα Subunits Induce Function...
Unknown Authors
Unknown Journal
Published: Dec 2016
2653 days before retraction
NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability
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Clinical Cancer Research
Open Access
Published: Nov 2016
72 citations
72 citations
2688 days before retraction
The broken “Off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance
Peter P. Ruvolo
BBA Clinical
Open Access
Published: Aug 2016
147 citations
147 citations
2780 days before retraction
Recurrent <i>PPP2R1A</i> Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth
Dorien Haesen, Layka Abbasi Asbagh, Rita Derua et al. (10 authors)
Cancer Research
Open Access
Published: Aug 2016
108 citations
108 citations
2781 days before retraction
Patient derived mutation W257G of PPP2R1A enhances cancer cell migration through SRC-JNK-c-Jun pathway
Ae Lee Jeong, Sora Han, Sunyi Lee et al. (10 authors)
Scientific Reports
Open Access
Published: Jun 2016
33 citations
33 citations
2838 days before retraction
Protein Phosphatase 2A as a Therapeutic Target in Acute Myeloid Leukemia
Elena Arriazu, Raffaella Pippa, María D. Odero
Frontiers in Oncology
Open Access
Published: Apr 2016
55 citations
55 citations
2900 days before retraction
Targeted next-generation sequencing for molecular diagnosis of endometriosis-associated ovarian cancer
Tze‐Kiong Er, Yu-Fa Su, Chun‐Chieh Wu et al. (12 authors)
Journal of Molecular Medicine
Published: Feb 2016
74 citations
74 citations
2939 days before retraction
PR55α Subunit of Protein Phosphatase 2A Supports the Tumorigenic and Metastatic Potential of Pancreatic Cancer Cells by Sustaining Hyperactive Oncogenic Signaling
Ashley L. Hein, Parthasarathy Seshacharyulu, Satyanarayana Rachagani et al. (9 authors)
Cancer Research
Open Access
Published: Feb 2016
58 citations
58 citations
2947 days before retraction
All roads lead to <scp>PP</scp>2A: exploiting the therapeutic potential of this phosphatase
Jaya Sangodkar, Caroline Farrington, Kimberly McClinch et al. (6 authors)
FEBS Journal
Open Access
Published: Oct 2015
281 citations
281 citations
3061 days before retraction
B56δ-related protein phosphatase 2A dysfunction identified in patients with intellectual disability
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Journal of Clinical Investigation
Open Access
Published: Jul 2015
109 citations
109 citations
3168 days before retraction
DNA damage checkpoint recovery and cancer development
Haiyong Wang, Xiaoshan Zhang, Lisong Teng et al. (4 authors)
Experimental Cell Research
Published: Apr 2015
82 citations
82 citations
3267 days before retraction
PP2A–B56ϵ complex is involved in dephosphorylation of γ-H2AX in the repair process of CPT-induced DNA double-strand breaks
Xiuying Li, Anuo Nan, Ying Xiao et al. (5 authors)
Toxicology
Published: Mar 2015
24 citations
24 citations
3291 days before retraction
Ligand-directed targeting of lymphatic vessels uncovers mechanistic insights in melanoma metastasis
Dawn R. Christianson, Andrey S. Dobroff, Bettina Proneth et al. (19 authors)
Proceedings of the National Academy of Sciences
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Published: Feb 2015
18 citations
18 citations
3325 days before retraction
Therapeutic Re-Activation of Protein Phosphatase 2A in Acute Myeloid Leukemia
Kavitha Ramaswamy, Barbara Spitzer, Alex Kentsis
Frontiers in Oncology
Open Access
Published: Feb 2015
27 citations
27 citations
3329 days before retraction
Restricted Protein Phosphatase 2A Targeting by Merkel Cell Polyomavirus Small T Antigen
Hyun Jin Kwun, Masahiro Shuda, Carlos J. Camacho et al. (7 authors)
Journal of Virology
Open Access
Published: Jan 2015
59 citations
59 citations
3333 days before retraction
Role of "oncogenic nexus" of CIP2A in breast oncogenesis: how does it work?
Pradip De, Jennifer Carlson, Brian Leyland‐Jones et al. (4 authors)
PubMed
Published: Jan 2015
16 citations
16 citations
3361 days before retraction
Inhibition of Protein Phosphatase 2A (PP2A) Prevents Mcl-1 Protein Dephosphorylation at the Thr-163/Ser-159 Phosphodegron, Dramatically Reducing Expression in Mcl-1-amplified Lymphoma Cells
Shanna K. Nifoussi, Nora Ratcliffe, Deborah L. Ornstein et al. (6 authors)
Journal of Biological Chemistry
Open Access
Published: Jun 2014
18 citations
18 citations
3558 days before retraction
PP2A-Mediated Regulation of Ras Signaling in G2 Is Essential for Stable Quiescence and Normal G1 Length
Nana Naetar, Vel Murugan, Larisa Litovchick et al. (10 authors)
Molecular Cell
Open Access
Published: May 2014
65 citations
65 citations
3585 days before retraction
PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity
Omer Gilan, Jeannine Diesch, M Amalia et al. (11 authors)
Oncogene
Open Access
Published: Mar 2014
22 citations
22 citations
3651 days before retraction
Temsirolimus enhances the efficacy of cetuximab in colon cancer through a CIP2A-dependent mechanism
Hsei-Wei Wang, Shung-Haur Yang, Guan-Da Huang et al. (13 authors)
Journal of Cancer Research and Clinical Oncology
Published: Feb 2014
27 citations
27 citations
3693 days before retraction
Endometrial Cancer
Jaume Reventós, Eva Colás, Elena Martínez et al. (13 authors)
Encyclopedia of Life Sciences
Published: Dec 2013
1 citation
1 citation
3749 days before retraction
Genetic amplification of<i>PPME1</i>in gastric and lung cancer and its potential as a novel therapeutic target
Jing Li, Sufang Han, Ziliang Qian et al. (12 authors)
Cancer Biology & Therapy
Open Access
Published: Nov 2013
23 citations
23 citations
3769 days before retraction
Over expression of PPP2R2C inhibits human glioma cells growth through the suppression of mTOR pathway
Yiling Fan, Lei Chen, Ji Wang et al. (5 authors)
FEBS Letters
Open Access
Published: Oct 2013
43 citations
43 citations
3808 days before retraction
Caracterización de nuevos perfiles moleculares en carcinoma de endometrio esporádico
Clara Isabel Cieza Borrella
Unknown Journal
Open Access
Published: Sep 2013
3821 days before retraction
B56γ Tumor-Associated Mutations Provide New Mechanisms for B56γ-PP2A Tumor Suppressor Activity
Yumiko Nobumori, Geoffrey Shouse, Yong Wu et al. (6 authors)
Molecular Cancer Research
Open Access
Published: May 2013
31 citations
31 citations
3941 days before retraction
Impaired expression of protein phosphatase 2A subunits enhances metastatic potential of human prostate cancer cells through activation of AKT pathway
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British Journal of Cancer
Open Access
Published: Apr 2013
40 citations
40 citations
3984 days before retraction
Infrequent mutations of the PPP2R1A and PPP2R1B genes in patients with ovarian cancer
Feng Wang, Yang Zou, Faying Liu et al. (12 authors)
Molecular Medicine Reports
Open Access
Published: Apr 2013
8 citations
8 citations
3993 days before retraction
Role of a Novel Functional Variant in the PPP2R1A Promoter on the Regulation of PP2A-Aalpha and the Risk of Hepatocellular Carcinoma
Huifeng Chen, Jianrong Mai, Jianxin Wan et al. (13 authors)
PLoS ONE
Open Access
Published: Mar 2013
17 citations
17 citations
4004 days before retraction
Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
Parthasarathy Seshacharyulu, Poomy Pandey, Kaustubh Datta et al. (4 authors)
Cancer Letters
Open Access
Published: Feb 2013
426 citations
426 citations
4041 days before retraction
Early stage uterine serous carcinoma: Management updates and genomic advances
Amanda N. Fader, Alessandro D. Santin, Paola A. Gehrig
Gynecologic Oncology
Published: Jan 2013
54 citations
54 citations
4080 days before retraction
PP2A-Mediated Anticancer Therapy
Weibo Chen, Zhong‐Xia Wang, Chunping Jiang et al. (4 authors)
Gastroenterology Research and Practice
Open Access
Published: Jan 2013
54 citations
54 citations
4091 days before retraction
BIOCHEMICAL AND CELLULAR MECHANISMS OF RETINA AND RETINAL PIGMENT EPITHELIUM APOPTOSIS
Srinivas R. Sripathi
Unknown Journal
Open Access
Published: Jan 2013
4091 days before retraction
Quick Stats
Total Citations:
163
Years Since Retraction:
1.7 year
Open Access:
Yes
Last Checked:
Jul 24, 2025