Retraction

PI3K/Akt pathway and Nanog maintain cancer stem cells in sarcomas

Paper Information

Record ID:
53797
Author(s):
Changhwan Yoon
Jun Lu
Brendan C Yi
Kevin K Chang
M Celeste Simon
Sandra Ryeom
Sam S Yoon
Journal:
Oncogenesis ( Springer - Nature Publishing Group )
Publication Date:
January 19, 2021
Retraction Date:
May 29, 2024 (1.5 year years ago)
Subjects:
Broad Categories:
Genetics Biology Biochemistry
Institutions:
Countries:
🇨🇳 China 🇺🇸 United States
Article Type:
Research Article
Publisher:
Springer - Nature Publishing Group
Open Access:
Yes
DOI:
10.1038/s41389-020-00300-z
PubMed ID:
33468992
Retraction PubMed ID:
38811548

Retraction Details

Retraction Reasons:
Nature of Retraction:

Retraction

Retraction Notice:
10.1038/s41389-024-00519-0
Additional Notes:

see also: https://pubpeer.com/publications/A03A70ADBD15AB9F1B2673A69C7DA9

Citations (54)

54
Total Citations
10
Post-Retraction
(18.5%)
44
Pre-Retraction
0
Same Day
Post-Retraction Citation Analysis
1 Within 30 days
10 Within 1 year
0 After 2+ years
307 Days since retraction (latest)
MAD2L1-mediated NANOG nuclear translocation: A critical factor in lung cancer chemoresistance
Hong‐Ye Zhao, Yongcun Liu, Longyu Zhu et al. (5 authors)
Cellular Signalling
Published: Apr 2025
3 citations
307 days after retraction
CD4 <sup>+</sup> FOXP3Exon2 <sup>+</sup> regulatory T cell frequency predicts breast cancer prognosis and survival
Clorinda Fusco, Francesca Di Rella, Antonietta Liotti et al. (29 authors)
Science Advances
Published: Jan 2025
1 citation
231 days after retraction
Targeting liposarcoma: unveiling molecular pathways and therapeutic opportunities
Hongliang Liu, Xi Wang, Lingyan Liu et al. (6 authors)
Frontiers in Oncology Open Access
Published: Dec 2024
196 days after retraction
Retraction: Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma
Changhwan Yoon, Soonweng Cho, Kevin K. Chang et al. (6 authors)
Molecular Cancer Research
Published: Nov 2024
156 days after retraction
Retraction: Chemotherapy Resistance in Diffuse-Type Gastric Adenocarcinoma Is Mediated by RhoA Activation in Cancer Stem-Like Cells
Changhwan Yoon, Soo‐Jeong Cho, Bülent Arman Aksoy et al. (7 authors)
Clinical Cancer Research Open Access
Published: Oct 2024
1 citation
139 days after retraction
Glycolysis-mTORC1 crosstalk drives proliferation of patient-derived endometrial cancer spheroid cells with ALDH activity
Haruka Ueda, Tatsuya Ishiguro, Yutaro Mori et al. (7 authors)
Cell Death Discovery Open Access
Published: Oct 2024
135 days after retraction
CD4+Foxp3E2+ regulatory T cell frequency predicts breast cancer prognosis and recurrence
Clorinda Fusco, Francesca Di Rella, Antonietta Liotti et al. (29 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Sep 2024
101 days after retraction
Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia
Dharaniya Sakthivel, Alexandra N. Brown-Suedel, Karla E. Rojas López et al. (18 authors)
Science Advances Open Access
Published: Aug 2024
65 days after retraction
Valsartan as a prophylactic treatment against breast cancer development and niche activation: What molecular sequels follow chronic AT-1R blockade?
A. Mansour, Mahmoud M. Khattab, Aiman S. El‐Khatib et al. (6 authors)
Life Sciences
Published: Jul 2024
2 citations
63 days after retraction
C-terminally phosphorylated p27 activates self-renewal driver genes to program cancer stem cell expansion, mammary hyperplasia and cancer
Seyedeh Fatemeh Razavipour, Hyunho Yoon, Kibeom Jang et al. (16 authors)
Nature Communications Open Access
Published: Jun 2024
5 citations
19 days after retraction
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling
Valerio Ciccone, Vittoria Simonis, Cinzia Del Gaudio et al. (7 authors)
Biochemical Pharmacology Open Access
Published: May 2024
7 citations
28 days before retraction
Unraveling the Significance of Nanog in the Generation of Embryonic Stem-like Cells from Spermatogonia Stem Cells: A Combined In Silico Analysis and In Vitro Experimental Approach
Nima Ghasemi, Hossein Azizi, Thomas Skutella
International Journal of Molecular Sciences Open Access
Published: Apr 2024
3 citations
30 days before retraction
Apoptosis Triggering in Breast Cancer Cells with Co-delivery of Melatonin and Doxorubicin Loaded into Human Adipose Mesenchymal Stem Cell Derived Exosomes
Moein Shirzad, Abdolreza Daraei, Hossein Najafzadehvarzi et al. (5 authors)
Research Square (Research Square) Open Access
Published: Apr 2024
56 days before retraction
Transcriptional regulation of cancer stem cell: regulatory factors elucidation and cancer treatment strategies
Zhengyue Zhang, Yanjie Zhang
Journal of Experimental & Clinical Cancer Research Open Access
Published: Apr 2024
6 citations
57 days before retraction
Targeted Inhibition of the PI3K/Akt/mTOR Signaling Axis: Potential for Sarcoma Therapy
Atif Khurshid Wani, Reena Singh, Nahid Akhtar et al. (10 authors)
Mini-Reviews in Medicinal Chemistry
Published: Jan 2024
4 citations
126 days before retraction
Mechanisms of Cancer Resistance to Various Therapies
Asiya Batool, Waseem Rashid, Kaneez Fatima et al. (4 authors)
Unknown Journal
Published: Jan 2024
7 citations
149 days before retraction
Glycolysis-mTORC1 crosstalk drives rapid proliferation in patient-derived endometrial cancer spheroids with ALDH activity
Tatsuya Ishiguro, Haruka Ueda, Yutaro Mori et al. (7 authors)
Research Square (Research Square) Open Access
Published: Dec 2023
1 citation
176 days before retraction
Down-Regulation of CYP3A4 by the KCa1.1 Inhibition Is Responsible for Overcoming Resistance to Doxorubicin in Cancer Spheroid Models
Susumu Ohya, Junko Kajikuri, Hiroaki Kito et al. (4 authors)
International Journal of Molecular Sciences Open Access
Published: Oct 2023
6 citations
215 days before retraction
Notum enhances gastric cancer stem-like cell properties through upregulation of Sox2 by PI3K/AKT signaling pathway
Yi Liu, Hui Chen, Lanshu Xiao et al. (11 authors)
Cellular Oncology Open Access
Published: Sep 2023
5 citations
246 days before retraction
Protein Kinase A Inhibition Epigenetically Silences<i>Ren1</i>
Jason P. Smith, Robert Paxton, Silvia Medrano et al. (6 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Sep 2023
250 days before retraction
ALDH1A1 confers resistance to RAF/MEK inhibitors in melanoma cells by maintaining stemness phenotype and activating PI3K/AKT signaling
Valerio Ciccone, Vittoria Simonis, Cinzia Del Gaudio et al. (7 authors)
Research Square (Research Square) Open Access
Published: Aug 2023
273 days before retraction
AR antagonists develop drug resistance through TOMM20 autophagic degradation-promoted transformation to neuroendocrine prostate cancer
Linglong Yin, Yubing Ye, Ling Zou et al. (14 authors)
Journal of Experimental & Clinical Cancer Research Open Access
Published: Aug 2023
8 citations
293 days before retraction
Advancement in precision diagnosis and therapeutic for triple-negative breast cancer: Harnessing diagnostic potential of CRISPR-cas &amp; engineered CAR T-cells mediated therapeutics
Vinayak Nayak, Sushmita Patra, Kshitij RB Singh et al. (13 authors)
Environmental Research
Published: Jul 2023
21 citations
319 days before retraction
Suppression of NANOG Expression Reduces Drug Resistance of Cancer Stem Cells in Glioblastoma
Jonhoi Smith, Melvin Field, Kimio Sugaya
Genes Open Access
Published: Jun 2023
17 citations
348 days before retraction
Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia
Dharaniya Sakthivel, Alexandra N. Brown-Suedel, Francesca Keane et al. (13 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: May 2023
2 citations
365 days before retraction
Phosphorylation of IWS1 by AKT maintains liposarcoma tumor heterogeneity through preservation of cancer stem cell phenotypes and mesenchymal-epithelial plasticity
Yu Wang, Hongji Zhang, Alessandro La Ferlita et al. (14 authors)
Oncogenesis Open Access
Published: May 2023
5 citations
369 days before retraction
FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells
Chunyan Xu, Wenlu Zhang, Chengxia Liu
PLoS ONE Open Access
Published: Apr 2023
11 citations
404 days before retraction
Phytochemicals in the Synthetic Era: A Potential Oncosuppressor against Cancer Stem Cells
Devangkumar Maru, Anmol Kumar
Anti-Cancer Agents in Medicinal Chemistry
Published: Feb 2023
457 days before retraction
Genome-Wide Analysis of lncRNA-mRNA Co-Expression Networks in CD133+/CD44+ Stem-like PDAC Cells
Giasemi C. Eptaminitaki, Apostolos Zaravinos, Dimitris Stellas et al. (10 authors)
Cancers Open Access
Published: Feb 2023
4 citations
477 days before retraction
Proteomic profiling of canine fibrosarcoma and adjacent peritumoral tissue
Erin Beebe, Amiskwia Pöschel, Laura Kunz et al. (9 authors)
Neoplasia Open Access
Published: Dec 2022
8 citations
537 days before retraction
Convergent Approaches to Delineate the Metabolic Regulation of Tumor Invasion by Hyaluronic Acid Biosynthesis
Adrian A. Shimpi, Matthew L. Tan, Michael Vilkhovoy et al. (10 authors)
Advanced Healthcare Materials Open Access
Published: Dec 2022
11 citations
538 days before retraction
Bioinformatics Analysis of RNA-seq Data Reveals Genes Related to Cancer Stem Cells in Colorectal Cancerogenesis
Kristian Urh, Nina Zidar, Emanuela Boštjančič
International Journal of Molecular Sciences Open Access
Published: Oct 2022
6 citations
576 days before retraction
Pleiotropic effects of DCLK1 in cancer and cancer stem cells
Dibyashree Chhetri, Srinivasan Vengadassalapathy, Santhosh Venkadassalapathy et al. (11 authors)
Frontiers in Molecular Biosciences Open Access
Published: Sep 2022
21 citations
611 days before retraction
Differentially expression and function of circular RNAs in ovarian cancer stem cells
Eun Jung Sohn
Journal of Ovarian Research Open Access
Published: Aug 2022
3 citations
651 days before retraction
The Role of AKT in Soft Tissue Sarcoma: Review and Insights
Yu Wang, Farhan Z. Ilyas, Mahsa Kheradmandi et al. (9 authors)
Molecular Cancer Research
Published: Jul 2022
2 citations
692 days before retraction
Aspirin sensitivity of PIK3CA-mutated Colorectal Cancer: potential mechanisms revisited
Daniella C. N. Hall, Ralf A. Benndorf
Cellular and Molecular Life Sciences Open Access
Published: Jul 2022
26 citations
698 days before retraction
STAT3-EMT axis in tumors: Modulation of cancer metastasis, stemness and therapy response
Mehrdokht Sadrkhanloo, Maliheh Entezari, Sima Orouei et al. (15 authors)
Pharmacological Research
Published: Jun 2022
120 citations
714 days before retraction
Genetic Screen in a Pre-Clinical Model of High-Grade Complex Karyotype Sarcoma Characterizes Drivers of Distinct Sarcoma Subtypes and Identifies New Therapeutic Vulnerabilities
Jack Freeland, Maria Muñoz, Edmond F. O’Donnell et al. (15 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Jun 2022
715 days before retraction
Convergent approaches to delineate the metabolic regulation of tumor invasion by hyaluronic acid biosynthesis
Adrian A. Shimpi, Matthew L. Tan, Michael Vilkhovoy et al. (10 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Jun 2022
720 days before retraction
RNA‐seq and ATAC‐seq analyses of multilineage differentiating stress enduring cells: Comparison with dermal fibroblasts
Xiao‐Qian Mao, Yan Cheng, Ruzhi Zhang et al. (7 authors)
Cell Biology International
Published: Jun 2022
4 citations
721 days before retraction
Chromobox 4 (CBX4) promotes tumor progression and stemness via activating CDC20 in gastric cancer
Wen Li, Honghui Chen, Zheng-Gen Wang et al. (6 authors)
Journal of Gastrointestinal Oncology Open Access
Published: Jun 2022
10 citations
728 days before retraction
The synergistic anticancer effect of salinomycin combined with cabazitaxel in CD44+ prostate cancer cells by downregulating wnt, NF-κB and AKT signaling
Suat Erdoğan, Rıza Serttas, Kader Turkekul et al. (4 authors)
Molecular Biology Reports
Published: Jun 2022
7 citations
728 days before retraction
5-O-(N-Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling
Darinthip Suksamai, Satapat Racha, Nicharat Sriratanasak et al. (10 authors)
Marine Drugs Open Access
Published: Mar 2022
17 citations
792 days before retraction
Abnormal Glycosylation in Cancer Cells and Cancer Stem Cells as a Therapeutic Target
Sabina Quader, Shihori Tanabe, Horacio Cabral
Advances in experimental medicine and biology
Published: Jan 2022
879 days before retraction
KCa1.1 K+ Channel Inhibition Overcomes Resistance to Antiandrogens and Doxorubicin in a Human Prostate Cancer LNCaP Spheroid Model
Susumu Ohya, Junko Kajikuri, Kyoko Endo et al. (5 authors)
International Journal of Molecular Sciences Open Access
Published: Dec 2021
14 citations
894 days before retraction
A Platform for Integrating and Sharing Cancer Stem Cell Data
Irena Parvanova, Kirill Borziak, Jennifer Guarino et al. (4 authors)
2021 43rd Annual International Conference of the IEEE Engineering in Medicine &amp; Biology Society (EMBC)
Published: Nov 2021
5 citations
940 days before retraction
Pongol Methyl Ether Inhibits Akt and Suppresses Cancer Stem Cell Phenotypes in Lung Cancer Cells
Arnon Silapech, Satapat Racha, Nithikoon Aksorn et al. (8 authors)
Pharmaceuticals Open Access
Published: Oct 2021
5 citations
946 days before retraction
The Multiple Faces of NANOG in Cancer: A Therapeutic Target to Chemosensitize Therapy-Resistant Cancers
Homa Fatma, Hifzur R. Siddique, S. Maurya
Epigenomics
Published: Oct 2021
14 citations
947 days before retraction
Salinomycin mediated therapeutic targeting of circulating stem like cell population in oral cancer
Shanaya Patel, Aditi Patel, Aishwarya Nair et al. (7 authors)
Journal of Biomolecular Structure and Dynamics
Published: Jul 2021
1 citation
1038 days before retraction
Discovery of Highly Oxidized Abietane Diterpenoids from the Roots of <i>Euphorbia fischeriana</i> with Anti‐tumor Activities
Jiangchun Wei, Yu‐Ning Gao, Dongdong Wang et al. (10 authors)
Chinese Journal of Chemistry
Published: Jul 2021
15 citations
1047 days before retraction
Quick Stats
Total Citations: 54
Years Since Retraction: 1.5 year
Open Access: Yes
Last Checked: Jul 24, 2025
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