Correction
PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis
Paper Information
Record ID:
56384
Author(s):
Journal:
Publication Date:
August 01, 2016
Retraction Date:
March 15, 2022
(3.7 years years ago)
Subjects:
Institutions:
- Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland
- McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland
- Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland
- Human Metabolome Technologies America, Inc., Boston, Massachusetts
- Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, Maryland
- Departments of Pediatrics, Medicine, Radiation Oncology, and Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, Maryland
Country:
🇺🇸 United StatesArticle Type:
Publisher:
American Association for Cancer Research
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Correction Details
Retraction Reasons:
Nature of Retraction:
Correction
Retraction Notice:
10.1158/0008-5472.CAN-21-4328Citations (230)
230
Total Citations69
Post-Retraction(30.0%)
160
Pre-Retraction1
Same DayPost-Retraction Citation Analysis
2
Within 30 days
28
Within 1 year
20
After 2+ years
1143
Days since retraction (latest)
De novo serine biosynthesis is protective in mitochondrial disease
Christopher B. Jackson, Anastasiia Marmyleva, Geoffray Monteuuis et al. (13 authors)
Cell Reports
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1143 days after retraction
A metabolic shift to the serine pathway induced by lipids fosters epigenetic reprogramming in nontransformed breast cells
Mariana Bustamante Eduardo, Gannon Cottone, Curtis W. McCloskey et al. (22 authors)
Science Advances
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Published: Mar 2025
1 citation
1 citation
1102 days after retraction
PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway
Xiaojin Liu, B. Liu, Jun-Wen Wang et al. (21 authors)
Journal of Experimental & Clinical Cancer Research
Open Access
Published: Mar 2025
1 citation
1 citation
1100 days after retraction
Quantification of the inputs and outputs of serine and glycine metabolism in cancer cells
Yuqi Wang, Hao Wu, Xun Hu
Archives of Biochemistry and Biophysics
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1082 days after retraction
Redox imbalance and hypoxia‐inducible factors: a multifaceted crosstalk
Ravi Ravi, Jogender Singh
FEBS Journal
Published: Feb 2025
2 citations
2 citations
1064 days after retraction
Metabolic Reprogramming at the Edge of Redox: Connections Between Metabolic Reprogramming and Cancer Redox State
José J. Serrano, Miguel Ángel Medina
International Journal of Molecular Sciences
Open Access
Published: Jan 2025
2 citations
2 citations
1031 days after retraction
New Emerging Therapeutic Strategies Based on Manipulation of the Redox Regulation Against Therapy Resistance in Cancer
Ahmad Nazari, Parisa Osati, Siavash Seifollahy Fakhr et al. (11 authors)
Antioxidants and Redox Signaling
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2 citations
2 citations
967 days after retraction
Innate immunity champions: The diverse functions of macrophages
Francesca Biscu, Anissa Zouzaf, Donatella Cicia et al. (5 authors)
European Journal of Immunology
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4 citations
4 citations
923 days after retraction
ALDH1L2 drives HCC progression through TAM polarization
Jiajun Li, Chi Zhang, Qingqing Zhou et al. (13 authors)
JHEP Reports
Open Access
Published: Sep 2024
4 citations
4 citations
912 days after retraction
Retraction: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis
Debangshu Samanta, Youngrok Park, Shaida A. Andrabi et al. (6 authors)
Cancer Research
Published: Sep 2024
904 days after retraction
Classical swine fever virus inhibits serine metabolism-mediated antiviral immunity by deacetylating modified PHGDH
Xiaowen Li, Yaoyao Huang, Xueyi Liu et al. (21 authors)
mBio
Open Access
Published: Aug 2024
3 citations
3 citations
898 days after retraction
Pharmacological induction of the hypoxia response pathway in Huh7 hepatoma cells limits proliferation but increases resilience under metabolic stress
Clémence Jacquemin, Walid El Orch, Olivier Diaz et al. (12 authors)
Cellular and Molecular Life Sciences
Open Access
Published: Jul 2024
5 citations
5 citations
868 days after retraction
E-cadherin Induces Serine Synthesis to Support Progression and Metastasis of Breast Cancer
Geonhui Lee, Claudia Wong, Anna Cho et al. (16 authors)
Cancer Research
Published: Jul 2024
6 citations
6 citations
840 days after retraction
PHGDH: a novel therapeutic target in cancer
Chae Min Lee, Yeseong Hwang, Minki Kim et al. (6 authors)
Experimental & Molecular Medicine
Open Access
Published: Jul 2024
19 citations
19 citations
839 days after retraction
Targeting phosphoglycerate dehydrogenase enzyme using ginger compounds to suppress thyroid cancer progression
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Narra X
Open Access
Published: May 2024
1 citation
1 citation
798 days after retraction
Preclinical efficacy of CBR-5884 against epithelial ovarian cancer cells by targeting the serine synthesis pathway
Kunxiang Gong, Yinger Huang, Yanqin Zheng et al. (6 authors)
Discover Oncology
Open Access
Published: May 2024
3 citations
3 citations
788 days after retraction
Iron metabolism: backfire of cancer cell stemness and therapeutic modalities
Yu Rong, Yinhui Hang, Hsiang‐i Tsai et al. (5 authors)
Cancer Cell International
Open Access
Published: May 2024
8 citations
8 citations
781 days after retraction
Cycling back to folate metabolism in cancer
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Nature Cancer
Open Access
Published: May 2024
16 citations
16 citations
779 days after retraction
<scp>EPAS1</scp>, a hypoxia‐ and f<scp>erroptosis‐related</scp> gene, promotes malignant behaviour of cervical cancer by <scp>ceRNA</scp> and <scp>super‐enhancer</scp>
Xiaoqin Lu, Wenyi Zhang, Jingyan Zhang et al. (6 authors)
Journal of Cellular and Molecular Medicine
Open Access
Published: May 2024
8 citations
8 citations
778 days after retraction
Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma
Manon Teisseire, Umakant Sahu, Julien Parola et al. (11 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Mar 2024
743 days after retraction
The enzymes of serine synthesis pathway in cancer metastasis
Lie Li, Yuting Qin, Yuping Chen
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
Published: Feb 2024
6 citations
6 citations
706 days after retraction
Unraveling the role of the mitochondrial one-carbon pathway in undifferentiated thyroid cancer by multi-omics analyses
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Nature Communications
Open Access
Published: Feb 2024
13 citations
13 citations
695 days after retraction
Role of cancer stem cell ecosystem on breast cancer metastasis and related mouse models
Xilei Peng, Haonan Dong, Lixing Zhang et al. (4 authors)
动物学研究
Open Access
Published: Jan 2024
2 citations
2 citations
657 days after retraction
The role of one-carbon amino acids in tumor-immune metabolism: From oncogenesis to therapy
Suchandrima Saha, Monisankar Ghosh
Elsevier eBooks
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1 citation
1 citation
657 days after retraction
Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
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Metabolism
Open Access
Published: Nov 2023
3 citations
3 citations
601 days after retraction
Cancer Metabolism under Limiting Oxygen Conditions
Laura C. Kim, Nicholas P. Lesner, M. Celeste Simon
Cold Spring Harbor Perspectives in Medicine
Published: Oct 2023
3 citations
3 citations
581 days after retraction
Environmental Determinants of Ferroptosis in Cancer
Yasaman Setayeshpour, Yunji Lee, Jen‐Tsan Chi
Cancers
Open Access
Published: Jul 2023
3 citations
3 citations
501 days after retraction
Transcriptional regulation of amino acid metabolism by KDM2B, in the context of ncPRC1.1 and in concert with MYC and ATF4
Evangelia Chavdoula, Vollter Anastas, Alessandro La Ferlita et al. (14 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jul 2023
1 citation
1 citation
480 days after retraction
Glutamine and amino acid metabolism as a prognostic signature and therapeutic target in endometrial cancer
Lirong Zhai, Xiao Yang, Yuan Cheng et al. (4 authors)
Cancer Medicine
Open Access
Published: Jun 2023
18 citations
18 citations
472 days after retraction
Role of Glucose Metabolic Reprogramming in Breast Cancer Progression and Drug Resistance
Lei Pan, Wenzhou Wang, Marisela Sheldon et al. (6 authors)
Cancers
Open Access
Published: Jun 2023
25 citations
25 citations
470 days after retraction
Competition between p53 and YY1 determines PHGDH expression and malignancy in bladder cancer
Tiezhu Shi, Zhihao Yuan, Yanying He et al. (9 authors)
Cellular Oncology
Published: Jun 2023
6 citations
6 citations
458 days after retraction
Inhibition of phosphoglycerate dehydrogenase induces ferroptosis and overcomes enzalutamide resistance in castration-resistant prostate cancer cells
Jinxiang Wang, Leli Zeng, Nisha Wu et al. (11 authors)
Drug Resistance Updates
Open Access
Published: Jun 2023
59 citations
59 citations
457 days after retraction
PHGDH promotes esophageal squamous cell carcinoma progression via Wnt/β-catenin pathway
Xiaoxuan Duan, Yihuan Chen, Kai Zhang et al. (10 authors)
Cellular Signalling
Published: May 2023
13 citations
13 citations
442 days after retraction
Serine synthesis pathway upregulated by E-cadherin is essential for the proliferation and metastasis of breast cancers
Geonhui Lee, Claudia Wong, An‐Na Cho et al. (16 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: May 2023
2 citations
2 citations
435 days after retraction
Serine Metabolic Reprogramming in Tumorigenesis, Tumor Immunity, and Clinical Treatment
Shunxi Wang, Yuan Xiaoxue, Song Guanbin et al. (6 authors)
Advances in Nutrition
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Published: May 2023
18 citations
18 citations
424 days after retraction
Elevated Nuclear PHGDH Synergistically Functions with cMyc to Reshape the Immune Microenvironment of Liver Cancer
Hongwen Zhu, Hua Yu, Hu Zhou et al. (5 authors)
Advanced Science
Open Access
Published: Apr 2023
16 citations
16 citations
401 days after retraction
Erchen decoction to reduce oxidative stress in dyslipidemia phlegm-dampness retention syndrome mice: In vivo mechanism revealed by metabolomics (liquid chromatography–mass spectrometry)
Jing Chen, Chao Ye, Zheng Yang et al. (9 authors)
Phytomedicine
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Published: Apr 2023
17 citations
17 citations
387 days after retraction
The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications
Zhuoya Jiao, Yunxia Pan, Fengyuan Chen
Molecular Diagnosis & Therapy
Published: Mar 2023
6 citations
6 citations
379 days after retraction
<i>De novo</i>serine biosynthesis is protective in mitochondrial disease
Christopher B. Jackson, Anastasiia Marmyleva, Ryan Awadhpersad et al. (12 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Mar 2023
2 citations
2 citations
374 days after retraction
The roles and molecular mechanisms of long non-coding RNA WT1-AS in the maintenance and development of gastric cancer stem cells
Xiaobei Zhang, Meng Jin, Shiqi Liu et al. (7 authors)
Heliyon
Open Access
Published: Mar 2023
3 citations
3 citations
371 days after retraction
Metabolomic analysis of vascular cognitive impairment due to hepatocellular carcinoma
Dan Zhu, Yamei Zhu, Lin Liu et al. (5 authors)
Frontiers in Neurology
Open Access
Published: Mar 2023
7 citations
7 citations
366 days after retraction
Amino acid metabolic reprogramming in tumor metastatic colonization
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Frontiers in Oncology
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18 citations
18 citations
364 days after retraction
Hypoxia-circular RNA crosstalk to promote breast cancer
Mohsen Karami Fath, Saba Shafieyari, Nasim Ardalani et al. (9 authors)
Pathology - Research and Practice
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2 citations
2 citations
355 days after retraction
Comprehensive analysis of PHGDH for predicting prognosis and immunotherapy response in patients with endometrial carcinoma
He Zhang, Weimin Kong, Xiaoling Zhao et al. (6 authors)
BMC Medical Genomics
Open Access
Published: Feb 2023
6 citations
6 citations
342 days after retraction
The role of hypoxia-inducible factors in breast cancer stem cell specification
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Pathology - Research and Practice
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10 citations
10 citations
321 days after retraction
Hypoxia truncates and constitutively activates the key cholesterol synthesis enzyme squalene monooxygenase
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eLife
Open Access
Published: Jan 2023
16 citations
16 citations
310 days after retraction
The Role of ESRP1 in the Regulation of PHGDH in Estrogen Receptor–Positive Breast Cancer
Yesim Gökmen–Polar, Yuan Gu, Alper Polar et al. (5 authors)
Laboratory Investigation
Published: Jan 2023
2 citations
2 citations
301 days after retraction
Novel insight into metabolic reprogrammming in cancer radioresistance: A promising therapeutic target in radiotherapy
Yilin Yu, Jie Yu, Shengfang Ge et al. (5 authors)
International Journal of Biological Sciences
Open Access
Published: Jan 2023
26 citations
26 citations
292 days after retraction
Comprehensive Analysis of PHGDH for Predicting Prognosis and Immunotherapy Response in Patients with Endometrial Carcinoma
He Zhang, Weimin Kong, Xiaoling Zhao et al. (6 authors)
Research Square (Research Square)
Open Access
Published: Nov 2022
239 days after retraction
Target enzymes in serine‐glycine‐one‐carbon metabolic pathway for cancer therapy
Wei Sun, Erhu Zhao, Hongjuan Cui
International Journal of Cancer
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18 citations
18 citations
238 days after retraction
Related Records
This article has multiple records in the database due to different notices:
Record #56383
Sep 04, 2024Quick Stats
Total Citations:
230
Years Since Retraction:
3.7 years
Open Access:
Yes
Last Checked:
Jul 24, 2025