Retraction
Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist
Paper Information
Record ID:
57254
Journal:
Publication Date:
August 21, 1998
Retraction Date:
August 02, 2024
(1.3 year years ago)
Subjects:
Institution:
Department of Physiology, University of Connecticut School of Medicine, Farmington, Connecticut 06030Country:
🇺🇸 United StatesArticle Type:
Publisher:
Elsevier
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (123)
123
Total Citations0
Post-Retraction119
Pre-Retraction0
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Sphingosine 1-Phosphate Signaling at the Skin Barrier Interface
Kana Masuda‐Kuroki, Anna Di Nardo
Biology
Open Access
Published: May 2022
24 citations
24 citations
800 days before retraction
DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery
Nicholas J. Kapolka, Geoffrey J. Taghon, Jacob B. Rowe et al. (7 authors)
Proceedings of the National Academy of Sciences
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Published: May 2020
71 citations
71 citations
1535 days before retraction
DCyFIR: a high-throughput CRISPR platform for multiplexed G protein-coupled receptor profiling and ligand discovery
NJ Kapolka, GJ Taghon, JB Rowe et al. (6 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jan 2020
1659 days before retraction
Lysophospholipid (S1P) receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database
Victoria A. Blaho, Jerold Chun, Deepa Jonnalagadda et al. (8 authors)
IUPHAR/BPS Guide to Pharmacology CITE
Open Access
Published: Sep 2019
3 citations
3 citations
1782 days before retraction
Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes
Yu Hisano, Mari Kono, Andréane Cartier et al. (18 authors)
The Journal of Experimental Medicine
Open Access
Published: May 2019
62 citations
62 citations
1891 days before retraction
Fingolimod: Lessons Learned and New Opportunities for Treating Multiple Sclerosis and Other Disorders
Jerold Chun, Yasuyuki Kihara, Deepa Jonnalagadda et al. (4 authors)
The Annual Review of Pharmacology and Toxicology
Open Access
Published: Jan 2019
110 citations
110 citations
2035 days before retraction
Heterotypic inter-GPCR ß-arrestin coupling regulates lymphatic endothelial junctional architecture in murine lymph nodes
Yu Hisano, Mari Kono, Eric Engelbrecht et al. (14 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Oct 2018
1 citation
1 citation
2129 days before retraction
Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System
Alessandro Cannavò, Daniela Liccardo, Klara Komici et al. (12 authors)
Frontiers in Pharmacology
Open Access
Published: Aug 2017
94 citations
94 citations
2537 days before retraction
S1P and LPA: Regulators of Immune Cell Egress and Ingress in Lymphoid Tissues
Masayuki Miyasaka, Akira Takeda, Erina Hata et al. (5 authors)
Elsevier eBooks
Published: Jan 2016
1 citation
1 citation
3136 days before retraction
Angiogenic effect of lysophosphatidic acid receptors on cervical cancer cells
Ruey‐Jien Chen, Chia‐Hung Chou, Shee‐Uan Chen et al. (4 authors)
Translational Cancer Research
Published: Oct 2015
3 citations
3 citations
3207 days before retraction
Towards selective lysophospholipid GPCR modulators
Julia K. Archbold, Jennifer L. Martin, Matthew J. Sweet
Trends in Pharmacological Sciences
Published: Apr 2014
16 citations
16 citations
3761 days before retraction
LPA receptor signaling: pharmacology, physiology, and pathophysiology
Yun C. Yung, Nicole C. Stoddard, Jerold Chun
Journal of Lipid Research
Open Access
Published: Mar 2014
654 citations
654 citations
3789 days before retraction
Lysophospholipid receptor nomenclature review: IUPHAR Review 8
Yasuyuki Kihara, Michael Maceyka, Sarah Spiegel et al. (4 authors)
British Journal of Pharmacology
Open Access
Published: Mar 2014
311 citations
311 citations
3801 days before retraction
Signal transduction in tumor angiogenesis
Timothy Hla, Nasser K. Altorki, Vivek Mittal
Cambridge University Press eBooks
Published: Dec 2013
3879 days before retraction
Isoforms of protein kinase C involved in phorbol ester-induced sphingosine 1-phosphate receptor 1 phosphorylation and desensitization
Marco Antonio Morquecho‐León, Silvana Bazúa‐Valenti, M. Teresa Romero‐Ávila et al. (4 authors)
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
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Published: Nov 2013
12 citations
12 citations
3915 days before retraction
Emerging therapeutic strategies to prevent infection-related microvascular endothelial activation and dysfunction
Ilyse Darwish, W. Conrad Liles
Virulence
Open Access
Published: Aug 2013
61 citations
61 citations
4014 days before retraction
Lysophosphatidic Acid Mediates Myeloid Differentiation within the Human Bone Marrow Microenvironment
Denis Evseenko, Brooke Latour, Wade Richardson et al. (10 authors)
PLoS ONE
Open Access
Published: May 2013
35 citations
35 citations
4096 days before retraction
Fingolimod: Direct CNS effects of sphingosine 1-phosphate (S1P) receptor modulation and implications in multiple sclerosis therapy
Aran Groves, Yasuyuki Kihara, Jerold Chun
Journal of the Neurological Sciences
Open Access
Published: Mar 2013
289 citations
289 citations
4154 days before retraction
Sphingosine and <scp>FTY720</scp> are potent inhibitors of the transient receptor potential melastatin 7 (<scp>TRPM7</scp>) channels
Xin Qin, Zhichao Yue, Baonan Sun et al. (10 authors)
British Journal of Pharmacology
Open Access
Published: Nov 2012
116 citations
116 citations
4280 days before retraction
Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models
Ville Härmä, Matias Knuuttila, Johannes Virtanen et al. (13 authors)
Oncogene
Open Access
Published: Sep 2011
41 citations
41 citations
4694 days before retraction
Regulation of Mammalian Physiology, Development, and Disease by the Sphingosine 1-Phosphate and Lysophosphatidic Acid Receptors
Victoria A. Blaho, Timothy Hla
Chemical Reviews
Open Access
Published: Sep 2011
144 citations
144 citations
4698 days before retraction
A mechanistically novel, first oral therapy for multiple sclerosis: the development of fingolimod (FTY720, Gilenya).
Jerold Chun, Volker Brinkmann
PubMed
Published: Sep 2011
172 citations
172 citations
4719 days before retraction
The Impact of Bioactive Lipids on Cardiovascular Development
Alexander Kleger, Stefan Liebau, Qiong Lin et al. (5 authors)
Stem Cells International
Open Access
Published: Jan 2011
27 citations
27 citations
4962 days before retraction
Aiming drug discovery at lysophosphatidic acid targets
Gábor Tigyi
British Journal of Pharmacology
Open Access
Published: May 2010
169 citations
169 citations
5195 days before retraction
Signal transduction responses to lysophosphatidic acid and sphingosine 1‐phosphate in human prostate cancer cells
Terra C. Gibbs, Maria V. Rubio, Zhihong Zhang et al. (6 authors)
The Prostate
Open Access
Published: Jun 2009
26 citations
26 citations
5525 days before retraction
Expression patterns of the lysophospholipid receptor genes during mouse early development
Hideyo Ohuchi, Aska Hamada, Hironao Matsuda et al. (8 authors)
Developmental Dynamics
Open Access
Published: Oct 2008
90 citations
90 citations
5770 days before retraction
Multiple Roles for Sphingolipids in Steroid Hormone Biosynthesis
Natasha C. Lucki, Marion B. Sewer
Sub-cellular biochemistry/Subcellular biochemistry
Open Access
Published: Aug 2008
53 citations
53 citations
5820 days before retraction
Sphingolipid signalling in the cardiovascular system: Good, bad or both?
Astrid E. Alewijnse, Stephan L.M. Peters
European Journal of Pharmacology
Published: Mar 2008
118 citations
118 citations
5983 days before retraction
Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors
William J. Valentine, James I. Fells, Donna Perygin et al. (10 authors)
Journal of Biological Chemistry
Open Access
Published: Mar 2008
37 citations
37 citations
5995 days before retraction
Imidazoline receptor antisera-selected protein: a unique modulator of neuronal differentiation.
Francis C. Dehle
Unknown Journal
Published: Jan 2008
6058 days before retraction
S1P-receptors in PC12 and transfected HEK293 cells: Molecular targets of hypotensive imidazoline I1 receptor ligands
Gerhard J. Molderings, Heinz Bönisch, Michael Brüss et al. (6 authors)
Neurochemistry International
Published: May 2007
23 citations
23 citations
6296 days before retraction
Horse Chestnut Extract Induces Contraction Force Generation in Fibroblasts through Activation of Rho/Rho Kinase
Tsutomu Fujimura, Shigeru Moriwaki, Mitsuyuki Hotta et al. (5 authors)
Biological and Pharmaceutical Bulletin
Open Access
Published: Jan 2006
10 citations
10 citations
6788 days before retraction
Novel GPCR Screening Approach: Indirect Identification of S1P Receptor Agonists in Antagonist Screening Using a Calcium Assay
Sandra Siehler, Danilo Guerini
Journal of Receptors and Signal Transduction
Published: Jan 2006
9 citations
9 citations
6788 days before retraction
Chapter 7 eNOS Regulation by Sphingosine 1-Phosphate and Caveolin
Junsuke Igarashi
Advances in molecular and cell biology
Published: Jan 2005
1 citation
1 citation
7153 days before retraction
Sphingosine-1-phosphate Signaling Promotes Critical Migratory Events in Vasculogenesis
Kelley M. Argraves, Brent A. Wilkerson, W. Scott Argraves et al. (6 authors)
Journal of Biological Chemistry
Open Access
Published: Sep 2004
64 citations
64 citations
7257 days before retraction
Ceramide 1-phosphate enhances calcium entry through voltage-operated calcium channels by a protein kinase C-dependent mechanism in GH4C1 rat pituitary cells
Kid Törnquist, Tomas Blom, Ramin Shariatmadari et al. (4 authors)
Biochemical Journal
Open Access
Published: Jun 2004
41 citations
41 citations
7353 days before retraction
Structural and functional characteristics of S1P receptors
Teresa Sánchez, Timothy Hla
Journal of Cellular Biochemistry
Published: May 2004
456 citations
456 citations
7373 days before retraction
Novel clusters of receptors for sphingosine‐1‐phosphate, sphingosylphosphorylcholine, and (lyso)‐phosphatidic acid: New receptors for “Old” ligands
Evi Kostenis
Journal of Cellular Biochemistry
Published: May 2004
83 citations
83 citations
7393 days before retraction
Membrane type 1–matrix metalloproteinase (MT1-MMP) cooperates with sphingosine 1–phosphate to induce endothelial cell migration and morphogenic differentiation
Stéphanie Langlois, Denis Gingras, Richard Béliveau
Blood
Open Access
Published: Dec 2003
98 citations
98 citations
7535 days before retraction
Common Signaling Pathways Link Activation of Murine PAR-1, LPA, and S1P Receptors to Proliferation of Astrocytes
Scott D. Sorensen, Olivier Nicole, Richard D. Peavy et al. (8 authors)
Molecular Pharmacology
Published: Oct 2003
205 citations
205 citations
7590 days before retraction
Pleiotropic actions of sphingosine-1-phosphate
Kenneth R. Watterson, Heidi Sankala, Sheldon Milstien et al. (4 authors)
Progress in Lipid Research
Published: Apr 2003
102 citations
102 citations
7788 days before retraction
Signaling and biological actions of sphingosine 1-phosphate
Timothy Hla
Pharmacological Research
Published: Apr 2003
277 citations
277 citations
7791 days before retraction
Identification of a Phosphothionate Analogue of Lysophosphatidic Acid (LPA) as a Selective Agonist of the LPA3 Receptor
Yutaka Hasegawa, James R. Erickson, Graham J. Goddard et al. (14 authors)
Journal of Biological Chemistry
Open Access
Published: Mar 2003
125 citations
125 citations
7798 days before retraction
Altered cAMP signaling induced by lysophosphatidic acid in senescent human diploid fibroblasts
Ik‐Soon Jang, Eui‐Ju Yeo, Ji‐Ae Park et al. (8 authors)
Biochemical and Biophysical Research Communications
Published: Mar 2003
15 citations
15 citations
7825 days before retraction
Ceramide 1-phosphate increases intracellular free calcium concentrations in thyroid FRTL-5 cells: evidence for an effect mediated by inositol 1,4,5-trisphosphate and intracellular sphingosine 1-phosphate
Susanna HÖGBACK, Petra Leppimäki, Britt Rudnäs et al. (6 authors)
Biochemical Journal
Open Access
Published: Feb 2003
44 citations
44 citations
7839 days before retraction
Quick Stats
Total Citations:
123
Years Since Retraction:
1.3 year
Open Access:
Yes
Last Checked:
Jul 24, 2025