Retraction
Lysophosphatidic acid stimulates the G-protein-coupled receptor EDG-1 as a low affinity agonist
Paper Information
Record ID:
57254
Journal:
Publication Date:
August 21, 1998
Retraction Date:
August 02, 2024
(1.3 year years ago)
Subjects:
Institution:
Department of Physiology, University of Connecticut School of Medicine, Farmington, Connecticut 06030Country:
🇺🇸 United StatesArticle Type:
Publisher:
Elsevier
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (123)
123
Total Citations0
Post-Retraction119
Pre-Retraction0
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Lysophosphatidic Acid Inhibits C-Type Natriuretic Peptide Activation of Guanylyl Cyclase-B
Sarah E. Abbey, Lincoln R. Potter
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Submicromolar doses of alkyl‐lysophospholipids induce rapid internalization, but not activation, of epidermal growth factor receptor and concomitant MAPK/ERK activation in A431 cells
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Comparative analysis of human and rat S1P5 (edg8): differential expression profiles and sensitivities to antagonists
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23 citations
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Characterization of <i>lpa<sub>2</sub></i> (<i>Edg4</i>) and <i>lpa<sub>1</sub></i>/<i>lpa<sub>2</sub></i> (<i>Edg2/Edg4</i>) Lysophosphatidic Acid Receptor Knockout Mice: Signaling Deficits without Obvious Phenotypic Abnormality Attributable to <i>lpa<sub>2</sub></i>
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Molecular and Cellular Biology
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Published: Sep 2002
315 citations
315 citations
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Sphingosine 1-Phosphate, a Key Cell Signaling Molecule
Sarah Spiegel, Sheldon Milstien
Journal of Biological Chemistry
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Published: Jul 2002
554 citations
554 citations
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Lysophosphatidic Acid Influences the Morphology and Motility of Young, Postmitotic Cortical Neurons
Nobuyuki Fukushima, Joshua A. Weiner, Dhruv Kaushal et al. (8 authors)
Molecular and Cellular Neuroscience
Published: Jun 2002
140 citations
140 citations
8098 days before retraction
Signaling of sphingosine-1-phosphate via the S1P/EDG-family of G-protein-coupled receptors
Michael Kluk
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Published: May 2002
312 citations
312 citations
8107 days before retraction
Convergence of Multiple Signaling Cascades at Glycogen Synthase Kinase 3: Edg Receptor-Mediated Phosphorylation and Inactivation by Lysophosphatidic Acid through a Protein Kinase C-Dependent Intracellular Pathway
Xianjun Fang, Shuangxing Yu, János L. Tanyi et al. (6 authors)
Molecular and Cellular Biology
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Published: Apr 2002
170 citations
170 citations
8159 days before retraction
Paper citing Lysophosphatidic acid stimulates the G-protein-cou...
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8175 days before retraction
Sphingosine 1-Phosphate, Present in Serum-derived Lipoproteins, Activates Matriptase
Christelle Benaud, Michael D. Oberst, John P. Hobson et al. (6 authors)
Journal of Biological Chemistry
Published: Mar 2002
89 citations
89 citations
8190 days before retraction
Dual Regulation of EDG1/S1P1 Receptor Phosphorylation and Internalization by Protein Kinase C and G-protein-coupled Receptor Kinase 2
Kenneth R. Watterson, Evelyn J. Johnston, Claire Chalmers et al. (7 authors)
Journal of Biological Chemistry
Open Access
Published: Feb 2002
81 citations
81 citations
8218 days before retraction
Critical Role of Lysophospholipids in the Pathophysiology, Diagnosis, and Management of Ovarian Cancer
Gordon B. Mills, Astrid Eder, Xianjun Fang et al. (21 authors)
Ovarian cancer
Published: Jan 2002
89 citations
89 citations
8249 days before retraction
Sphingosine 1-Phosphate Activates Nuclear Factor-κB through Edg Receptors
Sandra Siehler, Yuren Wang, Xiaomin Fan et al. (5 authors)
Journal of Biological Chemistry
Open Access
Published: Dec 2001
73 citations
73 citations
8280 days before retraction
A Single Amino Acid Determines Lysophospholipid Specificity of the S1P1 (EDG1) and LPA1 (EDG2) Phospholipid Growth Factor Receptors
De-an Wang, Zsolt Lőrincz, Debra L. Bautista et al. (6 authors)
Journal of Biological Chemistry
Open Access
Published: Dec 2001
110 citations
110 citations
8280 days before retraction
Subtype-specific, differential activities of the EDG family receptors for sphingosine-1-phosphate, a novel lysophospholipid mediator
Yoh Takuwa, Hiroyuki Okamoto, Noriko Takuwa et al. (6 authors)
Molecular and Cellular Endocrinology
Published: May 2001
67 citations
67 citations
8494 days before retraction
Sphingosine 1-phosphate receptors
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Prostaglandins & Other Lipid Mediators
Published: Apr 2001
140 citations
140 citations
8524 days before retraction
Lysophosphatidic acid and ovarian cancer: a paradigm for tumorogenesis and patient management
James R. Erickson, Yutaka Hasegawa, Xianjun Fang et al. (9 authors)
Prostaglandins & Other Lipid Mediators
Published: Apr 2001
28 citations
28 citations
8524 days before retraction
Role of the Sphingosine-1-Phosphate Receptor EDG-1 in PDGF-Induced Cell Motility
John P. Hobson, Hans Rosenfeldt, Larry S. Barak et al. (8 authors)
Science
Published: Mar 2001
425 citations
425 citations
8554 days before retraction
Paper citing Lysophosphatidic acid stimulates the G-protein-cou...
Unknown Authors
Unknown Journal
Published: Feb 2001
8582 days before retraction
Nrg-1 Belongs to the Endothelial Differentiation Gene Family of G Protein-coupled Sphingosine-1-phosphate Receptors
Renae L. Malek, Rachelle E. Toman, Lisa C. Edsall et al. (10 authors)
Journal of Biological Chemistry
Open Access
Published: Feb 2001
124 citations
124 citations
8583 days before retraction
Lysophosphatidic acid, a novel lipid growth factor for human thyroid cells: Over-expression of the high-affinity receptor edg4 in differentiated thyroid cancer
Klaus‐Martin Schulte, Andreas Beyer, Karl K�hrer et al. (5 authors)
International Journal of Cancer
Published: Jan 2001
99 citations
99 citations
8614 days before retraction
The Role and Clinical Applications of Bioactive Lysolipids in Ovarian Cancer
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Journal of the Society for Gynecologic Investigation
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Published: Jan 2001
55 citations
55 citations
8614 days before retraction
Effect of Phosphatidic Acid on Human Breast Cancer Cells Exposed to Doxorubicin
Daniel Slíva, Kevin Harvey, Rebekah Mason et al. (5 authors)
Cancer Investigation
Published: Jan 2001
22 citations
22 citations
8614 days before retraction
Identification of Edg1 Receptor Residues That Recognize Sphingosine 1-Phosphate
Abby L. Parrill, De-an Wang, Debra L. Bautista et al. (10 authors)
Journal of Biological Chemistry
Open Access
Published: Dec 2000
155 citations
155 citations
8645 days before retraction
Lysophosphatidic Acid Receptors
James J. A. Contos, Isao Ishii, Jerold Chun
Molecular Pharmacology
Published: Dec 2000
4 citations
4 citations
8645 days before retraction
Lysophosphatidic Acid Receptors
James J. A. Contos, Isao Ishii, Jerold Chun
Molecular Pharmacology
Published: Dec 2000
403 citations
403 citations
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Requirement for the <i>lp</i> <sub>A1</sub> lysophosphatidic acid receptor gene in normal suckling behavior
James J. A. Contos, Nobuyuki Fukushima, Joshua A. Weiner et al. (5 authors)
Proceedings of the National Academy of Sciences
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Published: Nov 2000
472 citations
472 citations
8655 days before retraction
Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells
Yutaka Yatomi, Tsukasa Ohmori, Ge Rile et al. (11 authors)
Blood
Published: Nov 2000
210 citations
210 citations
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Sphingosine 1-phosphate as a major bioactive lysophospholipid that is released from platelets and interacts with endothelial cells
Yutaka Yatomi, Tsukasa Ohmori, Ge Rile et al. (11 authors)
Blood
Published: Nov 2000
13 citations
13 citations
8661 days before retraction
Sphingosine 1-phosphate signalling via the endothelial differentiation gene family of G-protein-coupled receptors
Susan Pyne, Nigel J. Pyne
Pharmacology & Therapeutics
Published: Nov 2000
172 citations
172 citations
8675 days before retraction
Agonist-modulated Targeting of the EDG-1 Receptor to Plasmalemmal Caveolae
Junsuke Igarashi, Thomas Michel
Journal of Biological Chemistry
Published: Oct 2000
159 citations
159 citations
8706 days before retraction
Glypican‐4 is an FGF2‐binding heparan sulfate proteoglycan expressed in neural precursor cells
Kazuki Hagihara, Ken Watanabe, Jerold Chun et al. (4 authors)
Developmental Dynamics
Published: Sep 2000
88 citations
88 citations
8716 days before retraction
Dynamic modeling of EDG1 receptor structural changes induced by site-directed mutations
Debra L. Bautista, Daniel L. Baker, D Wang et al. (8 authors)
Journal of Molecular Structure THEOCHEM
Published: Sep 2000
14 citations
14 citations
8736 days before retraction
Sphingosine 1-phosphate signalling in mammalian cells
Susan Pyne, Nigel J. Pyne
Biochemical Journal
Open Access
Published: Jul 2000
700 citations
700 citations
8784 days before retraction
Paper citing Lysophosphatidic acid stimulates the G-protein-cou...
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Published: Jul 2000
8798 days before retraction
Modulation of tight junction function by G protein-coupled events
Ann M. Hopkins, D. Li, Randall J. Mrsny et al. (5 authors)
Advanced Drug Delivery Reviews
Published: Jun 2000
62 citations
62 citations
8799 days before retraction
Induction of Tumor Cell Differentiation
R.A. Flickinger
Differentiation
Published: Jun 2000
2 citations
2 citations
8828 days before retraction
Potential Role of EDG Receptors and Lysophospholipids as their Endogenous Ligands in the Respiratory Tract
Kurt Racké, Rainer Hammermann, Uwe R. Juergens
Pulmonary Pharmacology & Therapeutics
Published: Jun 2000
21 citations
21 citations
8828 days before retraction
Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2.
Astrid Eder, Takayo Sasagawa, M. Mao et al. (5 authors)
PubMed
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173 citations
173 citations
8828 days before retraction
Regulation of Expression of EDG Family Receptors in Human Prostate Cancer Cell Lines
Terra C. Gibbs, Yuhuan Xie, Kathryn E. Meier
Annals of the New York Academy of Sciences
Published: Apr 2000
16 citations
16 citations
8889 days before retraction
LPA as a Paracrine Mediator of Adipocyte Growth and Function
Céline Pagès, Alexia Girard, Olivier Jeanneton et al. (8 authors)
Annals of the New York Academy of Sciences
Open Access
Published: Apr 2000
36 citations
36 citations
8889 days before retraction
Structural Features of EDG1 Receptor‐Ligand Complexes Revealed by Computational Modeling and Mutagenesis
Abby L. Parrill, Daniel L. Baker, De–An Wang et al. (8 authors)
Annals of the New York Academy of Sciences
Published: Apr 2000
26 citations
26 citations
8889 days before retraction
Pharmacological Characterization of Phospholipid Growth‐Factor Receptors
Gábor Tigyi, David J. Fischer, Daniel L. Baker et al. (11 authors)
Annals of the New York Academy of Sciences
Published: Apr 2000
22 citations
22 citations
8889 days before retraction
Characterization of Endogenous and Heterologously Expressed LPA Receptor Subtypes
David J. Fischer, Kimiko Murakami‐Murofushi, Gábor Tigyi
Annals of the New York Academy of Sciences
Published: Apr 2000
4 citations
4 citations
8889 days before retraction
Functions of a new family of sphingosine-1-phosphate receptors
Sarah Spiegel, Sheldon Milstien
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
Open Access
Published: Apr 2000
194 citations
194 citations
8889 days before retraction
Lysophospholipid Growth Factors in the Initiation, Progression, Metastases, and Management of Ovarian Cancer
Xianjun Fang, Douglas C. Gaudette, Tatsuro Furui et al. (14 authors)
Annals of the New York Academy of Sciences
Published: Apr 2000
245 citations
245 citations
8889 days before retraction
Sphingosine‐1‐Phosphate Signaling via the EDG‐1 Family of G‐Protein‐Coupled Receptors
Timothy Hla, Menq-Jer Lee, Nicolas Ancellin et al. (8 authors)
Annals of the New York Academy of Sciences
Published: Apr 2000
56 citations
56 citations
8889 days before retraction
Quick Stats
Total Citations:
123
Years Since Retraction:
1.3 year
Open Access:
Yes
Last Checked:
Jul 24, 2025