Expression of concern
Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase
Paper Information
Record ID:
60342
Author(s):
Publication Date:
December 07, 2007
Retraction Date:
December 05, 2024
(<1 year years ago)
Institutions:
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, M5G 1X5, Ontario, Canada
- The Wellcome Trust and Cancer Research UK Gurdon Institute, and the Department of Zoology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK
- Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada
- Department of Molecular and Cellular Biology, Instituto de Biología Molecular de Barcelona c. Jordi Girona 18-2608034 Barcelona, Spain
Countries:
Article Type:
Publisher:
American Association for the Advancement of Science (AAAS)
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Expression of concern Details
Retraction Reasons:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1126/science.adu7744Citations (887)
887
Total Citations12
Post-Retraction(1.4%)
873
Pre-Retraction2
Same DayPost-Retraction Citation Analysis
0
Within 30 days
12
Within 1 year
0
After 2+ years
225
Days since retraction (latest)
CDKs-mediated phosphorylation of PNKP is required for end-processing of single-strand DNA gaps on Okazaki Fragments and genome stability
Kaima Tsukada, T. Miyake, Rikiya Imamura et al. (9 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Published: Jul 2021
1224 days before retraction
Dealing with transcription-blocking DNA damage: Repair mechanisms, RNA polymerase II processing and human disorders
Nan Jia, Chaowan Guo, Yuka Nakazawa et al. (6 authors)
DNA repair
Open Access
Published: Jul 2021
45 citations
45 citations
1228 days before retraction
Two redundant ubiquitin-dependent pathways of BRCA1 localization to DNA damage sites
Alana Sherker, Natasha Chaudhary, Salomé Adam et al. (6 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jul 2021
3 citations
3 citations
1233 days before retraction
MCM7 Ubiquitination Regulates CMG Helicase Disassembly In Human
Qianqian Sun, Kun Liu, Fangzhou Li et al. (8 authors)
Research Square (Research Square)
Open Access
Published: Jul 2021
1234 days before retraction
RNF8–CDH1 Co-Expression Predicts Clinical Benefit of Chemoradiotherapy in Triple-Negative Breast Cancer
Chieh‐Ni Kao, Sin‐Hua Moi, Ming‐Feng Hou et al. (6 authors)
Journal of Personalized Medicine
Open Access
Published: Jul 2021
4 citations
4 citations
1241 days before retraction
To Join or Not to Join: Decision Points Along the Pathway to Double-Strand Break Repair vs. Chromosome End Protection
Stephanie M. Ackerson, Carlan Romney, P. Logan Schuck et al. (4 authors)
Frontiers in Cell and Developmental Biology
Open Access
Published: Jul 2021
27 citations
27 citations
1242 days before retraction
TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression
Lin Lyu, Tsung-Chin Lin, Nami McCarty
Oncogene
Open Access
Published: Jul 2021
22 citations
22 citations
1253 days before retraction
Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance
Qinglei Hang, Liyong Zeng, Li Wang et al. (12 authors)
Nature Communications
Open Access
Published: Jun 2021
23 citations
23 citations
1255 days before retraction
RNF168-mediated localization of BARD1 recruits the BRCA1-PALB2 complex to DNA damage
John J. Krais, Yifan Wang, Pooja Patel et al. (6 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jun 2021
1 citation
1 citation
1259 days before retraction
ATM: Main Features, Signaling Pathways, and Its Diverse Roles in DNA Damage Response, Tumor Suppression, and Cancer Development
Liem Phan, Abdol-Hossein Rezaeian
Genes
Open Access
Published: May 2021
66 citations
66 citations
1285 days before retraction
BRCA1: a key player at multiple stages of homologous recombination in DNA double-strand break repair
Yidan Liu, Lin‐Yu Lu
Genome Instability & Disease
Published: May 2021
7 citations
7 citations
1288 days before retraction
Ubiquitin ligases in cancer: Functions and clinical potentials
Shanshan Duan, Michele Pagano
Cell chemical biology
Open Access
Published: May 2021
54 citations
54 citations
1305 days before retraction
Ubiquitin-mediated DNA damage response is synthetic lethal with G-quadruplex stabilizer CX-5461
Tehmina Masud, Charles Soong, Hong Xu et al. (7 authors)
Scientific Reports
Open Access
Published: May 2021
12 citations
12 citations
1308 days before retraction
Ubiquitylation in DNA double-strand break repair
Mengfan Tang, Siting Li, Junjie Chen
DNA repair
Open Access
Published: May 2021
13 citations
13 citations
1308 days before retraction
Critical DNA damaging pathways in tumorigenesis
Jake A. Kloeber, Zhenkun Lou
Seminars in Cancer Biology
Open Access
Published: Apr 2021
16 citations
16 citations
1321 days before retraction
COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
Amila Suraweera, Neha S. Gandhi, Sam Beard et al. (13 authors)
Communications Biology
Open Access
Published: Apr 2021
15 citations
15 citations
1326 days before retraction
Investigating Molecular Determinants of Cancer Cell Resistance to Ionizing Radiation Through an Integrative Bioinformatics Approach
Halil Ibrahim Toy, Gökhan Karakülah, Panagiota I. Kontou et al. (6 authors)
Frontiers in Cell and Developmental Biology
Open Access
Published: Apr 2021
10 citations
10 citations
1338 days before retraction
RNF8‐ubiquitinated KMT5A is required for RNF168‐induced H2A ubiquitination in response to DNA damage
Xiaopeng Lu, Min Xu, Qian Zhu et al. (10 authors)
The FASEB Journal
Published: Mar 2021
14 citations
14 citations
1364 days before retraction
NF-κB–induced R-loop accumulation and DNA damage select for nucleotide excision repair deficiencies in adult T cell leukemia
Yunlong He, Nagesh Pasupala, Huijun Zhi et al. (13 authors)
Proceedings of the National Academy of Sciences
Open Access
Published: Mar 2021
36 citations
36 citations
1375 days before retraction
How Is the Fidelity of Proteins Ensured in Terms of Both Quality and Quantity at the Endoplasmic Reticulum? Mechanistic Insights into E3 Ubiquitin Ligases
Ji An Kang, Young Joo Jeon
International Journal of Molecular Sciences
Open Access
Published: Feb 2021
10 citations
10 citations
1385 days before retraction
Herpes Simplex Virus 1 Manipulates Host Cell Antiviral and Proviral DNA Damage Responses
Max E. Mertens, David M. Knipe
mBio
Open Access
Published: Feb 2021
18 citations
18 citations
1396 days before retraction
Targeting RNF8 effectively reverses cisplatin and doxorubicin resistance in endometrial cancer
Ben Yang, Ke Wang, Yingchun Wan et al. (4 authors)
Biochemical and Biophysical Research Communications
Open Access
Published: Feb 2021
9 citations
9 citations
1401 days before retraction
RNF168 is highly expressed in esophageal squamous cell carcinoma and contributes to the malignant behaviors in association with the Wnt/β-catenin signaling pathway
Yunjiu Gou, Dacheng Jin, Shengliang He et al. (5 authors)
Aging
Open Access
Published: Jan 2021
13 citations
13 citations
1410 days before retraction
Histone Ubiquitination: An Integrative Signaling Platform in Genome Stability
Francesca Mattiroli, Lorenza Penengo
Trends in Genetics
Open Access
Published: Jan 2021
169 citations
169 citations
1415 days before retraction
Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination
Kyosuke Nakamura, Georg Kustatscher, Constance Alabert et al. (13 authors)
Molecular Cell
Open Access
Published: Jan 2021
83 citations
83 citations
1420 days before retraction
Structural insights into DNA double-strand break signaling
Rashmi Panigrahi, J. N. Mark Glover
Biochemical Journal
Published: Jan 2021
5 citations
5 citations
1422 days before retraction
Catalysis-dependent and redundant roles of Dma1 and Dma2 in maintenance of genome stability in Saccharomyces cerevisiae
Andrew R. Yoblinski, Seoyoung Chung, Sophie B. Robinson et al. (6 authors)
Journal of Biological Chemistry
Open Access
Published: Jan 2021
1434 days before retraction
Regulation of DNA double-strand break repair pathway choice: a new focus on 53BP1
Fan Zhang, Zihua Gong
Journal of Zhejiang University SCIENCE B
Open Access
Published: Jan 2021
27 citations
27 citations
1434 days before retraction
Control of Genome through Variative Nature of Histone-Modifying Ubiquitin Ligases
А. В. Бачева, Nataliya N. Gotmanova, Alexey A. Belogurov et al. (4 authors)
Biochemistry (Moscow)
Published: Jan 2021
10 citations
10 citations
1434 days before retraction
Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A
Kyung Yong Lee, Anindya Dutta
Cell Reports
Open Access
Published: Jan 2021
14 citations
14 citations
1434 days before retraction
Destruction or Reconstruction: A Subtle Liaison between the Proteolytic and Signaling Role of Protein Ubiquitination in Spermatogenesis
Giovanna Berruti
Advances in experimental medicine and biology
Published: Jan 2021
3 citations
3 citations
1434 days before retraction
The end protection problem—an unexpected twist in the tail
Phil Ruis, Simon J. Boulton
Genes & Development
Open Access
Published: Dec 2020
42 citations
42 citations
1443 days before retraction
<p>UBE2N Regulates Paclitaxel Sensitivity of Ovarian Cancer via Fos/P53 Axis</p>
Qiuyuan Zhu, Jieyuan Chen, Peipei Pan et al. (5 authors)
OncoTargets and Therapy
Open Access
Published: Dec 2020
13 citations
13 citations
1465 days before retraction
Phosphoproteomics reveals novel modes of function and inter‐relationships among PIKKs in response to genotoxic stress
Sapir Schlam‐Babayov, Ariel Bensimon, Michal Harel et al. (7 authors)
The EMBO Journal
Open Access
Published: Nov 2020
47 citations
47 citations
1476 days before retraction
The ubiquitin ligase RNF8 regulates Rho GTPases and promotes cytoskeletal changes and motility in triple‐negative breast cancer cells
Bruno Pereira De Carvalho, Yi‐Jye Chern, Jiabei He et al. (4 authors)
FEBS Letters
Open Access
Published: Nov 2020
5 citations
5 citations
1478 days before retraction
Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break
Jieqiong Lou, David G. Priest, Ashleigh Solano et al. (5 authors)
Nature Communications
Open Access
Published: Nov 2020
30 citations
30 citations
1483 days before retraction
Targeting DNA repair pathways: mechanisms and potential applications in cancer therapy
Yongtai Bai, Weibin Wang, Jiadong Wang
Genome Instability & Disease
Open Access
Published: Nov 2020
5 citations
5 citations
1495 days before retraction
Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex
Rebecca J. Burge, Andreas Damianou, Anthony J. Wilkinson et al. (5 authors)
PLoS Pathogens
Open Access
Published: Oct 2020
29 citations
29 citations
1500 days before retraction
Extracellular matrix stiffness determines DNA repair efficiency and cellular sensitivity to genotoxic agents
Min Deng, Jing Lin, Somaira Nowsheen et al. (11 authors)
Science Advances
Open Access
Published: Sep 2020
67 citations
67 citations
1546 days before retraction
ATM‐Dependent Recruitment of BRD7 is required for Transcriptional Repression and DNA Repair at DNA Breaks Flanking Transcriptional Active Regions
Kaishun Hu, Yu Li, Wenjing Wu et al. (15 authors)
Advanced Science
Open Access
Published: Sep 2020
36 citations
36 citations
1554 days before retraction
Targeting RNF8 Effectively Reverse Cisplatin and Doxorubicin Resistance in Endometrial Cancer
Ben Yang, Wang Ke, Yingchun Wan et al. (4 authors)
Research Square (Research Square)
Open Access
Published: Sep 2020
1555 days before retraction
Targeted modulation of E3 ligases using engineered ubiquitin variants
Nicole J. LeBlanc, Evan Mallette, Wei Zhang
FEBS Journal
Open Access
Published: Aug 2020
20 citations
20 citations
1557 days before retraction
The Chromatin Response to Double-Strand DNA Breaks and Their Repair
Radoslav Aleksandrov, Rossitsa Hristova, Stoyno Stoynov et al. (4 authors)
Cells
Open Access
Published: Aug 2020
62 citations
62 citations
1581 days before retraction
Non-canonical function of DGCR8 in DNA double-strand break repair signaling and tumor radioresistance
Qinglei Hang, Liyong Zeng, Li Wang et al. (11 authors)
Research Square (Research Square)
Open Access
Published: Aug 2020
1582 days before retraction
USP7 Is a Master Regulator of Genome Stability
Gabrielle J. Valles, Irina Bezsonova, Roger Woodgate et al. (4 authors)
Frontiers in Cell and Developmental Biology
Open Access
Published: Aug 2020
90 citations
90 citations
1583 days before retraction
RNF8 Promotes Epithelial–Mesenchymal Transition in Lung Cancer Cells via Stabilization of Slug
Jingyu Kuang, Min Lu, Chuanyang Liu et al. (10 authors)
Molecular Cancer Research
Open Access
Published: Aug 2020
24 citations
24 citations
1584 days before retraction
Regulation of Histone Ubiquitination in Response to DNA Double Strand Breaks
Lanni Aquila, Boyko S. Atanassov
Cells
Open Access
Published: Jul 2020
32 citations
32 citations
1603 days before retraction
<i>Leishmania</i>differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex
Rebecca J. Burge, Andreas Damianou, Anthony J. Wilkinson et al. (5 authors)
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jul 2020
2 citations
2 citations
1610 days before retraction
SIRT6 mono-ADP ribosylates KDM2A to locally increase H3K36me2 at DNA damage sites to inhibit transcription and promote repair
Sarallah Rezazadeh, David Yang, Seyed Ali Biashad et al. (11 authors)
Aging
Open Access
Published: Jun 2020
36 citations
36 citations
1624 days before retraction
Camptothecin induced DDX5 degradation increased the camptothecin resistance of osteosarcoma
Xingkai Zhao, Miao Bao, Fengmin Zhang et al. (4 authors)
Experimental Cell Research
Published: Jun 2020
7 citations
7 citations
1626 days before retraction
Quick Stats
Total Citations:
887
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 24, 2025