Retraction
Polyphyllin I inhibits growth and invasion of cisplatin-resistant gastric cancer cells by partially inhibiting CIP2A/PP2A/Akt signaling axis
Paper Information
Record ID:
62555
Author(s):
Journal:
Publication Date:
August 23, 2018
Retraction Date:
March 04, 2025
(<1 year years ago)
Subjects:
Institutions:
Country:
🇨🇳 ChinaArticle Type:
Publisher:
Elsevier
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (68)
68
Total Citations3
Post-Retraction(4.4%)
65
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
1
Within 30 days
3
Within 1 year
0
After 2+ years
111
Days since retraction (latest)
Emerging Trends in Designing the Dendrimer-Based Drug Delivery for Antineoplastic Therapies
Mohammad Adnan Raza, Anjila Firdous, Umesh Gupta et al. (6 authors)
ACS Applied Bio Materials
Published: Jun 2025
111 days after retraction
Polyphyllin I inhibits ovarian cancer growth by inducing G0/G1 phase arrest and inhibiting the c-Myc signaling pathway
Qing Tang, Kun Huang, Mengjie Li et al. (8 authors)
Medical Oncology
Published: Jun 2025
100 days after retraction
Steroidal saponins: a treasure trove of natural resources that require urgent development
Zhiqiang Sun, Chunmei Zhong, Hongdan Zhang et al. (8 authors)
Phytochemistry Reviews
Published: Mar 2025
27 days after retraction
Paper citing Polyphyllin I inhibits growth and invasion of cisp...
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Unknown Journal
Published: Feb 2025
8 days before retraction
Sculponeatin A induces mitochondrial dysfunction in non‐small cell lung cancer through WWP2‐mediated degradation of mitochondrial STAT3
Fang Wan, Qian Chen, Xuewen Liu et al. (12 authors)
British Journal of Pharmacology
Published: Feb 2025
8 days before retraction
Reversal of chemotherapy resistance in gastric cancer with traditional Chinese medicine as sensitizer: potential mechanism of action
Chencong Zhou, Kaihan Wu, M. Gu et al. (6 authors)
Frontiers in Oncology
Open Access
Published: Feb 2025
1 citation
1 citation
12 days before retraction
Dissection of transcriptome and metabolome insights into the polyphyllin biosynthesis in Paris
Ping Xu, Qi Mi, Xiaoye Zhang et al. (11 authors)
BMC Plant Biology
Open Access
Published: Feb 2025
1 citation
1 citation
17 days before retraction
Understanding the regulatory landscape of protein phosphatase 2A (PP2A): Pharmacological modulators and potential therapeutics
David B. Neale, Jonathan C. Morris, Nicole M. Verrills et al. (4 authors)
Pharmacology & Therapeutics
Published: Feb 2025
4 citations
4 citations
31 days before retraction
Synergic effects of DL-limonene, R-limonene, and cisplatin on AKT, PI3K, and mTOR gene expression in MDA-MB-231 and 5637 cell lines
Fatemeh Malek Motie, Mehdi Soltani Howyzeh, Ali Ghanbari Asad
International Journal of Biological Macromolecules
Published: Oct 2024
6 citations
6 citations
154 days before retraction
The role of Rhizoma Paridis saponins on anti-cancer: the potential mechanism and molecular targets
Famin Ke, Ranqi Zhang, Rui Chen et al. (8 authors)
Heliyon
Open Access
Published: Sep 2024
3 citations
3 citations
184 days before retraction
Reprogramming of glucose metabolism: The hallmark of malignant transformation and target for advanced diagnostics and treatments
Qing Tang, Siqi Wu, Baiming Zhao et al. (11 authors)
Biomedicine & Pharmacotherapy
Open Access
Published: Aug 2024
16 citations
16 citations
204 days before retraction
G protein pathway suppressor 2 suppresses aerobic glycolysis through RACK1-mediated HIF-1α degradation in breast cancer
Yuan Si, Hongling Ou, Xin Jin et al. (12 authors)
Free Radical Biology and Medicine
Published: Jun 2024
2 citations
2 citations
251 days before retraction
Research trends and hotspots of polyphyllin in high-incidence cancers: A bibliometric analysis
Xin Jiang, Zhen Liu, Runlan Wan et al. (10 authors)
Heliyon
Open Access
Published: Mar 2024
1 citation
1 citation
368 days before retraction
Advances in antitumor activity and mechanism of natural steroidal saponins: A review of advances, challenges, and future prospects
Fengge Wang, Liang Lu, Ma Yu et al. (14 authors)
Phytomedicine
Published: Feb 2024
15 citations
15 citations
389 days before retraction
Research progress of Paris polyphylla in the treatment of digestive tract cancers
Jia Wang, Baoyi Ni, Jing Wang et al. (10 authors)
Discover Oncology
Open Access
Published: Feb 2024
2 citations
2 citations
391 days before retraction
Polyphyllin I attenuates the invasion and metastasis via downregulating GRP78 in drug-resistant hepatocellular carcinoma cells
Haiyan Du, Haochen Wu, Qinyang Kang et al. (10 authors)
Aging
Open Access
Published: Nov 2023
5 citations
5 citations
484 days before retraction
Acetylation of MOB1 mediates polyphyllin II-reduced lysosome biogenesis in breast cancer by promoting the cytoplasmic retention of the YAP/TFEB coactivator complex
Yuliang Ren, Hui Wu, Miao Tan et al. (12 authors)
Phytomedicine
Published: Oct 2023
6 citations
6 citations
506 days before retraction
Polyphyllins in cancer therapy: A systematic review and meta-analysis of animal studies
Yan Bai, Mengmeng Li, Dongjie Geng et al. (8 authors)
Phytomedicine
Published: Sep 2023
2 citations
2 citations
531 days before retraction
A state-of-art of underlying molecular mechanisms and pharmacological interventions/nanotherapeutics for cisplatin resistance in gastric cancer
Jitendra Gupta, Abdulrahman T. Ahmed, Nahla A. Tayyib et al. (10 authors)
Biomedicine & Pharmacotherapy
Open Access
Published: Sep 2023
17 citations
17 citations
547 days before retraction
Polyphyllin <scp>VII</scp> induces autophagy‐dependent ferroptosis in human gastric cancer through targeting T‐lymphokine‐activated killer cell‐originated protein kinase
Yuchen Xiang, Fang Wan, Yuliang Ren et al. (12 authors)
Phytotherapy Research
Open Access
Published: Aug 2023
12 citations
12 citations
556 days before retraction
Steroidal Saponins: Naturally Occurring Compounds as Inhibitors of the Hallmarks of Cancer
Salwa Bouabdallah, Amna Al-Maktoum, Amr Amin
Cancers
Open Access
Published: Jul 2023
61 citations
61 citations
582 days before retraction
Polyphyllin I suppressed the apoptosis of intervertebral disc nucleus pulposus cells induced by IL-1β by miR-503-5p/Bcl-2 axis
Lei Yuan, Hui Miao, Ding Heng et al. (6 authors)
Journal of Orthopaedic Surgery and Research
Open Access
Published: Jun 2023
4 citations
4 citations
615 days before retraction
Sculponeatin A promotes the ETS1-SYVN1 interaction to induce SLC7A11/xCT-dependent ferroptosis in breast cancer
Peng Peng, Yuliang Ren, Fang Wan et al. (13 authors)
Phytomedicine
Published: Jun 2023
19 citations
19 citations
635 days before retraction
Human pancreatic cancer patients with Epithelial-to-Mesenchymal Transition and an aggressive phenotype show a disturbed balance in Protein Phosphatase Type 2A expression and functionality
Jos van Pelt, Bob Meeusen, Rita Derua et al. (7 authors)
Journal of Translational Medicine
Open Access
Published: May 2023
6 citations
6 citations
663 days before retraction
Geroprotective interventions in the 3xTg mouse model of Alzheimer’s disease
Michelle M. Sonsalla, Dudley W. Lamming
GeroScience
Open Access
Published: Apr 2023
11 citations
11 citations
698 days before retraction
Polyphyllin I suppresses the gastric cancer growth by promoting cancer cell ferroptosis
Fang Zheng, Yeshu Wang, Qunfang Zhang et al. (11 authors)
Frontiers in Pharmacology
Open Access
Published: Apr 2023
28 citations
28 citations
700 days before retraction
Polyphyllin I suppressed the apoptosis of intervertebral disc nucleus pulposus cells Induced By IL-1 β by miR-503-5p/Bcl-2 axis
Lei Yuan, Hui Miao, Ding Heng et al. (6 authors)
Research Square (Research Square)
Open Access
Published: Mar 2023
725 days before retraction
From Basic Science to Clinical Practice: The Role of Cancerous Inhibitor of Protein Phosphatase 2A (CIP2A)/p90 in Cancer
Beibei Chen, Huihui Hu, Xiaobing Chen
Frontiers in Genetics
Open Access
Published: Feb 2023
5 citations
5 citations
739 days before retraction
Therapeutic effects on cancer of the active ingredients in rhizoma paridis
Jie Li, Jinhao Jia, Weiwei Zhu et al. (6 authors)
Frontiers in Pharmacology
Open Access
Published: Feb 2023
22 citations
22 citations
742 days before retraction
Cancerous inhibitor of protein phosphatase 2A enhances chemoresistance of gastric cancer cells to oxaliplatin
Yongxun Zhao, Li-Bin Ma, Ze Yang et al. (6 authors)
World Journal of Gastrointestinal Oncology
Open Access
Published: Feb 2023
2 citations
2 citations
750 days before retraction
Effects of Organophosphate-Degrading Bacteria on the Plant Biomass, Active Medicinal Components, and Soil Phosphorus Levels of Paris polyphylla var. yunnanensis
Zhuowei Li, Yueheng Wang, Chang Liu et al. (8 authors)
Plants
Open Access
Published: Jan 2023
4 citations
4 citations
763 days before retraction
Cytotoxic steroidal glycosides from the rhizomes of Paris polyphylla var. yunnanensis
Yang Liu, Meiyou Liu, Lin-Lin Bi et al. (10 authors)
Phytochemistry
Published: Dec 2022
13 citations
13 citations
796 days before retraction
Anticancer Effect of Polyphyllin I in Suppressing Stem Cell-Like Properties of Hepatocellular Carcinoma via the AKT/GSK-3β/β-Catenin Signaling Pathway
Mianmian Liao, Haiyan Du, Bing Wang et al. (6 authors)
Oxidative Medicine and Cellular Longevity
Open Access
Published: Oct 2022
15 citations
15 citations
864 days before retraction
Polyphyllin I improves myocardial damage in coronary artery disease via modulating lipid metabolism and myocardial apoptosis
Yang Zhao, Xu-Ming Yang, Mingchun An
Journal of Biochemical and Molecular Toxicology
Published: Sep 2022
9 citations
9 citations
897 days before retraction
Rhizoma Paridis saponins suppresses vasculogenic mimicry formation and metastasis in osteosarcoma through regulating miR-520d-3p/MIG-7 axis
Nan Yao, Jing Zhou, Yantao Jiang et al. (7 authors)
Journal of Pharmacological Sciences
Open Access
Published: Sep 2022
7 citations
7 citations
911 days before retraction
Targeting transforming growth factor‐ß signalling for cancer prevention and intervention: Recent advances in developing small molecules of natural origin
Devesh Tewari, Anu Priya, Anusha Bishayee et al. (4 authors)
Clinical and Translational Medicine
Open Access
Published: Apr 2022
30 citations
30 citations
1068 days before retraction
Developments in the Antitumor Activity, Mechanisms of Action, Structural Modifications, and Structure-Activity Relationships of Steroidal Saponins
Xuefeng Huang, Ren-Feng An, Wenjin Zhang
Mini-Reviews in Medicinal Chemistry
Published: Feb 2022
5 citations
5 citations
1110 days before retraction
Polyphyllin E Inhibits Proliferation, Migration and Invasion of Ovarian Cancer Cells by Down-Regulating the AKT/NF-κB Pathway
Yinglei Liu, Yang Cao, Haili Kai et al. (7 authors)
Biological and Pharmaceutical Bulletin
Open Access
Published: Feb 2022
12 citations
12 citations
1110 days before retraction
Promising Therapeutic Candidate for Myocardial Ischemia/Reperfusion Injury: What Are the Possible Mechanisms and Roles of Phytochemicals?
Cong Chen, Lin-Tong Yu, Bai-Ru Cheng et al. (17 authors)
Frontiers in Cardiovascular Medicine
Open Access
Published: Feb 2022
29 citations
29 citations
1111 days before retraction
The direct STAT3 inhibitor 6-ethoxydihydrosanguinarine exhibits anticancer activity in gastric cancer
Xuewen Liu, Xin Jin, Hongling Ou et al. (12 authors)
Acta Materia Medica
Open Access
Published: Jan 2022
13 citations
13 citations
1158 days before retraction
G protein pathway suppressor 2 suppresses gastric cancer by destabilizing epidermal growth factor receptor
Yuan Si, Haitao Zhang, Peng Peng et al. (13 authors)
Cancer Science
Open Access
Published: Oct 2021
14 citations
14 citations
1244 days before retraction
Polyphyllin I Inhibits Propionibacterium acnes-Induced IL-8 Secretion in HaCaT Cells by Downregulating the CD36/NOX1/ROS/NLRP3/IL-1β Pathway
Shuyun Yang, Ying Jiang, Xiuqin Yu et al. (11 authors)
Evidence-based Complementary and Alternative Medicine
Open Access
Published: Sep 2021
14 citations
14 citations
1260 days before retraction
Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells
Yuchen Xiang, Peng Peng, Xuewen Liu et al. (13 authors)
Acta Pharmacologica Sinica
Open Access
Published: Sep 2021
37 citations
37 citations
1267 days before retraction
Exploring the Effect of Polyphyllin I on Hepatitis B Virus-related Liver Cancer through Network Pharmacology and in vitro Experiments
Puhua Zeng, Shuxian Yu, Wenhui Gao et al. (7 authors)
Combinatorial Chemistry & High Throughput Screening
Published: Aug 2021
7 citations
7 citations
1296 days before retraction
Cyanidin‐3‐<i>O</i>‐glucoside and cisplatin inhibit proliferation and downregulate the PI3K/AKT/mTOR pathway in cervical cancer cells
Li Xu, Jin Zhao, Tingcai Yan et al. (8 authors)
Journal of Food Science
Published: Apr 2021
28 citations
28 citations
1406 days before retraction
A Review of the Pharmacology, Application, Ethnopharmacology, Phytochemistry, Quality Control, Processing, Toxicology, and Pharmacokinetics of Paridis Rhizoma
Song‐Tao Liu, Huan Yu, Ajiao Hou et al. (10 authors)
World Journal of Traditional Chinese Medicine
Open Access
Published: Apr 2021
9 citations
9 citations
1411 days before retraction
Polyphyllin I reverses the resistance of osimertinib in non-small cell lung cancer cell through regulation of PI3K/Akt signaling
Lei Lai, Qiuping Shen, Yingjie Wang et al. (7 authors)
Toxicology and Applied Pharmacology
Published: Apr 2021
29 citations
29 citations
1433 days before retraction
Paris saponin VII, a direct activator of AMPK, induces autophagy and exhibits therapeutic potential in non-small-cell lung cancer
Yuchen Xiang, Jie Shen, Yuan Si et al. (11 authors)
Chinese Journal of Natural Medicines
Published: Mar 2021
27 citations
27 citations
1464 days before retraction
Recent advances in phytochemical-based Nano-formulation for drug-resistant Cancer
Mahesh P. More, Sagar R. Pardeshi, Chandrakantsing V. Pardeshi et al. (8 authors)
Medicine in Drug Discovery
Open Access
Published: Jan 2021
73 citations
73 citations
1501 days before retraction
Mycorrhizas Affect Polyphyllin Accumulation of Paris polyphylla var. yunnanensis through Promoting PpSE Expression
Li HaiLing, Lingfeng Xu, LI Zhuo-wei et al. (7 authors)
Phyton
Open Access
Published: Jan 2021
8 citations
8 citations
1523 days before retraction
Quick Stats
Total Citations:
68
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 23, 2025