Retraction
Bruton’s tyrosine kinase inhibition attenuates the cardiac dysfunction caused by cecal ligation and puncture in mice
Paper Information
Record ID:
62577
Author(s):
Journal:
Publication Date:
September 05, 2019
Retraction Date:
January 26, 2025
(<1 year years ago)
Subjects:
Institutions:
- 1William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
- 2Department of Drug Science and Technology, University of Turin, Turin, Italy
- 3Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany
- 4Septomics Research Center, Jena University Hospital, Jena, Germany
- 5Department of Operative Intensive Care and Intermediate Care, RWTH University Hospital Aachen, Aachen, Germany
Countries:
Article Type:
Publisher:
Frontiers
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Retraction Reasons:
Nature of Retraction:
Retraction
Retraction Notice:
10.3389/fimmu.2025.1561869Additional Notes:
see also: https://pubpeer.com/publications/D667186D2ED12E79733956DC1003DC
Citations (37)
37
Total Citations1
Post-Retraction(2.7%)
36
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
1
Within 30 days
1
Within 1 year
0
After 2+ years
6
Days since retraction (latest)
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BTK and MMP9 regulate NLRP3 inflammasome-dependent cytokine and NET responses in primary neutrophils
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The role of the NLRP3 inflammasome and pyroptosis in cardiovascular diseases
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173 citations
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473 days before retraction
DLK1 overexpression improves sepsis-induced cardiac dysfunction and fibrosis in mice through the TGF-β1/Smad3 signaling pathway and MMPs
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5 citations
486 days before retraction
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9 citations
9 citations
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The double sides of NLRP3 inflammasome activation in sepsis
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Bruton’s tyrosine kinase inhibition attenuates disease progression by reducing renal immune cell invasion in mice with hemolytic-uremic syndrome
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<scp>KLF13</scp> overexpression protects sepsis‐induced myocardial injury and <scp>LPS</scp>‐induced inflammation and apoptosis
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11 citations
11 citations
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Bruton’s Tyrosine Kinase Deficiency Ameliorates Antimicrobial Host Defense during Peritonitis Induced by Pathogenic Escherichia coli
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Infection and Immunity
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Regulation of the Tec family of non-receptor tyrosine kinases in cardiovascular disease
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24 citations
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NF-κB Signaling and Inflammation—Drug Repurposing to Treat Inflammatory Disorders?
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Biology
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53 citations
1065 days before retraction
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17 citations
17 citations
1090 days before retraction
NF-κB Signaling and Inflammation – Drug Repurposing to Treat Inflammatory Disorders?
Annabell Roberti, Laura Elizabeth Chaffey, David R. Greaves
Unknown Journal
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Published: Jan 2022
12 citations
12 citations
1102 days before retraction
Inhibition of Bruton’s Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats
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13 citations
13 citations
1126 days before retraction
Bruton's TK regulates myeloid cell recruitment during acute inflammation
Gareth S. D. Purvis, Haidée Aranda-Tavío, Keith M. Channon et al. (4 authors)
British Journal of Pharmacology
Open Access
Published: Dec 2021
17 citations
17 citations
1140 days before retraction
Bruton’s tyrosine kinase drives neuroinflammation and anxiogenic behavior in mouse models of stress
Simantini Ghosh, Zaidan Mohammed, Itender Singh
Journal of Neuroinflammation
Open Access
Published: Dec 2021
19 citations
19 citations
1142 days before retraction
Distinct Effects of Ibrutinib and Acalabrutinib on Mouse Atrial and Sinoatrial Node Electrophysiology and Arrhythmogenesis
Jari M. Tuomi, Loryn J. Bohne, Tristan W. Dorey et al. (7 authors)
Journal of the American Heart Association
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Published: Nov 2021
12 citations
12 citations
1181 days before retraction
Clinical Trials of the BTK Inhibitors Ibrutinib and Acalabrutinib in Human Diseases Beyond B Cell Malignancies
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Frontiers in Oncology
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25 citations
25 citations
1186 days before retraction
Inhibition of Bruton’s tyrosine kinase activity attenuates trauma-induced multiple organ dysfunction in rats
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bioRxiv (Cold Spring Harbor Laboratory)
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Published: Sep 2021
1 citation
1 citation
1220 days before retraction
BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
Zsofia Bittner, Xiao Liu, Maria Mateo Tortola et al. (32 authors)
The Journal of Experimental Medicine
Open Access
Published: Sep 2021
54 citations
54 citations
1221 days before retraction
Multifaceted Immunomodulatory Effects of the BTK Inhibitors Ibrutinib and Acalabrutinib on Different Immune Cell Subsets – Beyond B Lymphocytes
Sining Zhu, Samantha Gokhale, Jaeyong Jung et al. (9 authors)
Frontiers in Cell and Developmental Biology
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Published: Aug 2021
41 citations
41 citations
1262 days before retraction
Structure-activity relationship investigation for imidazopyrazole-3-carboxamide derivatives as novel selective inhibitors of Bruton's tyrosine kinase
Dandan Zhang, Guiqing Xu, Jie Zhao et al. (12 authors)
European Journal of Medicinal Chemistry
Published: Jul 2021
8 citations
8 citations
1277 days before retraction
Phyto‐pharmacological perspective of Silymarin: A potential prophylactic or therapeutic agent for <scp>COVID</scp>‐19, based on its promising immunomodulatory, anti‐coagulant and anti‐viral property
Partha Palit, Aparna Mukhopadhyay, Debprasad Chattopadhyay
Phytotherapy Research
Open Access
Published: Apr 2021
24 citations
24 citations
1393 days before retraction
Targeting the NLRP3 Inflammasome via BTK
Alexander N.R. Weber
Frontiers in Cell and Developmental Biology
Open Access
Published: Feb 2021
29 citations
29 citations
1431 days before retraction
Pharmacological Inhibition of BTK reduces neuroinflammation and stress induced anxiety<i>in vivo</i>
Simantini Ghosh, Zaidan Mohammed, Itender Singh
bioRxiv (Cold Spring Harbor Laboratory)
Open Access
Published: Jan 2021
1 citation
1 citation
1475 days before retraction
Bruton’s tyrosine kinase inhibition attenuates oxidative stress in systemic immune cells and renal compartment during sepsis-induced acute kidney injury in mice
Ahmed Nadeem, Sheikh F. Ahmad, Naif O. Al‐Harbi et al. (9 authors)
International Immunopharmacology
Published: Nov 2020
41 citations
41 citations
1541 days before retraction
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure
Caroline E. O’Riordan, Gareth S. D. Purvis, Debora Collotta et al. (13 authors)
Frontiers in Immunology
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26 citations
26 citations
1572 days before retraction
The hidden role of NLRP3 inflammasome in obesity‐related COVID‐19 exacerbations: Lessons for drug repurposing
Ilaria Bertocchi, Federica Foglietta, Debora Collotta et al. (7 authors)
British Journal of Pharmacology
Open Access
Published: Aug 2020
34 citations
34 citations
1630 days before retraction
Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation
Gareth S. D. Purvis, Massimo Collino, Haidée Aranda-Tavío et al. (14 authors)
British Journal of Pharmacology
Open Access
Published: Jul 2020
63 citations
63 citations
1670 days before retraction
The hidden role of NLRP3 inflammasome in diabesity-related COVID-19 exacerbations: lessons for drug repurposing
Ilaria Bertocchi, Federica Foglietta, Debora Collotta et al. (7 authors)
Authorea (Authorea)
Open Access
Published: Jun 2020
1 citation
1 citation
1675 days before retraction
Exploring the beneficial role of telmisartan in sepsis-induced myocardial injury through inhibition of high-mobility group box 1 and glycogen synthase kinase-3β/nuclear factor-κB pathway
Yan Jin, Hong Wang, Jing Li et al. (7 authors)
Korean Journal of Physiology and Pharmacology
Open Access
Published: Jun 2020
5 citations
5 citations
1676 days before retraction
Quick Stats
Total Citations:
37
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 23, 2025