Retraction
Inhibition of 5-lipoxygenase triggers apoptosis in pancreatic cancer cells
Paper Information
Record ID:
63045
Journal:
Publication Date:
December 05, 2014
Retraction Date:
December 09, 2024
(<1 year years ago)
Subjects:
Institution:
Department of Gastroenterology, Affliliated Hospital of Nantong University, Jiangsu, Nantong 226001, P.R. ChinaCountry:
🇨🇳 ChinaArticle Type:
Publisher:
Spandidos
Open Access:
Yes
DOI:
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (43)
43
Total Citations2
Post-Retraction(4.7%)
41
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
2
Within 1 year
0
After 2+ years
113
Days since retraction (latest)
Multimodal evaluation of lipoxygenase-targeting NSAIDs using integrated in vitro, SAR, in silico, cytotoxicity towards MCF-7 cell line, DNA docking and MD simulation approaches
Ambar Iqbal, Wasim Abbas, Samina Ejaz et al. (7 authors)
International Journal of Biological Macromolecules
Published: Apr 2025
113 days after retraction
Substituted aryl piperazine ligands as new dual 5-hLOX/COX-2 inhibitors. Synthesis, biological and computational studies
Michelle Muñoz-Osses, Elizabeth Navarrete, Pilar Morales et al. (9 authors)
Bioorganic Chemistry
Published: Mar 2025
82 days after retraction
Zileuton, a 5-Lypoxigenase Inhibitor, is Antiparasitic and Prevents Inflammation in the Chronic Stage of Heart Chagas Disease
Mayra Fernanda Ricci, Estela Mariana Guimarães Lourenço, Rafaela das Dores Pereira et al. (14 authors)
ACS Infectious Diseases
Published: Nov 2024
11 days before retraction
In Vitro Evaluation of Pharmacokinetic Properties of Selected Dual COX-2 and 5-LOX Inhibitors
Jelena Bošković, Vladimir Dobričić, Jelena Savić et al. (7 authors)
Pharmaceuticals
Open Access
Published: Oct 2024
65 days before retraction
Arachidonic acid metabolism as a novel pathogenic factor in gastrointestinal cancers
Weiqin Lu, Aihemaitijiang Aihaiti, Paziliya Abudukeranmu et al. (5 authors)
Molecular and Cellular Biochemistry
Published: Jul 2024
1 citation
1 citation
158 days before retraction
Lipoxygenases at the Intersection of Infection and Carcinogenesis
Abdul-Saleem Amoah, Nikolay B. Pestov, Tatyana V. Korneenko et al. (6 authors)
International Journal of Molecular Sciences
Open Access
Published: Apr 2024
6 citations
6 citations
251 days before retraction
Inflammation and gut barrier function-related genes and colorectal cancer risk in western European populations
Hannah Mandle, Mazda Jenab, Marc J. Gunter et al. (31 authors)
Mutagenesis
Open Access
Published: Mar 2024
6 citations
6 citations
279 days before retraction
Pathological and pharmacological functions of the metabolites of polyunsaturated fatty acids mediated by cyclooxygenases, lipoxygenases, and cytochrome P450s in cancers
Yi-Wen Meng, Jun‐Yan Liu
Pharmacology & Therapeutics
Published: Feb 2024
11 citations
11 citations
297 days before retraction
Cannabis in anticancer drug development
Ernest Matambo, Andrew G. Mtewa, Tadala Mzengo et al. (4 authors)
Elsevier eBooks
Published: Jan 2024
343 days before retraction
ALOX5 acts as a key role in regulating the immune microenvironment in intrahepatic cholangiocarcinoma, recruiting tumor-associated macrophages through PI3K pathway
Jialu Chen, Yue Tang, Delong Qin et al. (7 authors)
Journal of Translational Medicine
Open Access
Published: Dec 2023
12 citations
12 citations
355 days before retraction
The ALOX5 inhibitor Zileuton regulates tumor-associated macrophage M2 polarization by JAK/STAT and inhibits pancreatic cancer invasion and metastasis
Weimin Hu, Si-Qing Liu, Kongfan Zhu et al. (8 authors)
International Immunopharmacology
Published: Jun 2023
32 citations
32 citations
538 days before retraction
Tannic acid may ameliorate doxorubicin-induced changes in oxidative stress parameters in rat spleen
Duygu Kizir, Melike Karaman, Hamid Ceylan
Naunyn-Schmiedeberg s Archives of Pharmacology
Published: Jun 2023
16 citations
16 citations
553 days before retraction
Membrane Lipid Derivatives: Roles of Arachidonic Acid and Its Metabolites in Pancreatic Physiology and Pathophysiology
Cándido Ortiz-Placín, Alba Castillejo-Rufo, Matías Estarás et al. (4 authors)
Molecules
Open Access
Published: May 2023
12 citations
12 citations
565 days before retraction
Ferroptosis in gastrointestinal cancer: from mechanisms to implications
Ruoxi Zhang, Rui Kang, Daolin Tang
Cancer Letters
Open Access
Published: Mar 2023
26 citations
26 citations
626 days before retraction
Carborane-Based Analog of Rev-5901 Attenuates Growth of Colon Carcinoma In Vivo
Svetlana Paskaš, Blagoje Murganić, Robert Kuhnert et al. (6 authors)
Molecules
Open Access
Published: Jul 2022
3 citations
3 citations
879 days before retraction
Leukotrienes promote stem cell self-renewal and chemoresistance in acute myeloid leukemia
Alec W. Stranahan, Iryna Berezniuk, Sohini Chakraborty et al. (6 authors)
Leukemia
Published: Apr 2022
5 citations
5 citations
961 days before retraction
Lipoxins and Resolvins in Patients With Pancreatic Cancer: A Preliminary Report
Wojciech Błogowski, Katarzyna Dołęgowska, Anna Deskur et al. (5 authors)
Frontiers in Oncology
Open Access
Published: Jan 2022
11 citations
11 citations
1063 days before retraction
Pancreatic Cancer and Platelets Crosstalk: A Potential Biomarker and Target
Shaoshan Mai, Iwona Inkielewicz‐Stępniak
Frontiers in Cell and Developmental Biology
Open Access
Published: Nov 2021
20 citations
20 citations
1125 days before retraction
Zileuton inhibits arachidonate-5-lipoxygenase to exert antitumor effects in preclinical cervical cancer models
Liling Li, Yifang Xiao, Zhengzheng Xu et al. (4 authors)
Cancer Chemotherapy and Pharmacology
Published: Sep 2021
14 citations
14 citations
1193 days before retraction
ALOX5‐5‐HETE promotes gastric cancer growth and alleviates chemotherapy toxicity via MEK/ERK activation
Jianjun Tang, Chuang Zhang, Jingjing Lin et al. (6 authors)
Cancer Medicine
Open Access
Published: Jun 2021
29 citations
29 citations
1275 days before retraction
Targeting ferroptosis in pancreatic cancer: a double-edged sword
Xin Chen, Rui Kang, Guido Kroemer et al. (4 authors)
Trends in cancer
Published: May 2021
107 citations
107 citations
1299 days before retraction
Relation between ABCB1 overexpression and COX2 and ALOX5 genes in human erythroleukemia cell lines
Mariana Teixeira Santos Figueiredo Salgado, Alessandra Costa Lopes, Estela Fernandes e Silva et al. (11 authors)
Prostaglandins & Other Lipid Mediators
Published: May 2021
1 citation
1 citation
1311 days before retraction
Polyphenolic Profile of Callistemon viminalis Aerial Parts: Antioxidant, Anticancer and In Silico 5-LOX Inhibitory Evaluations
Shahenda Mahgoub, Nashwa Hashad, Sahar A. Ali et al. (7 authors)
Molecules
Open Access
Published: Apr 2021
19 citations
19 citations
1325 days before retraction
Evaluation of cyrhetrenyl and ferrocenyl precursors as 5-lipoxygenase inhibitors – biological and computational studies
Michelle Muñoz-Osses, Javiera Quiroz, Yesseny Vásquez‐Martínez et al. (10 authors)
New Journal of Chemistry
Published: Jan 2021
5 citations
5 citations
1438 days before retraction
Targeting the eicosanoid pathway in hepatocellular carcinoma.
Anshuli Razdan, Nathan Main, Vincent Chiu et al. (7 authors)
Unknown Journal
Published: Jan 2021
8 citations
8 citations
1438 days before retraction
CaMKIIγ regulates the viability and self‐renewal of acute myeloid leukaemia stem‐like cells by the Alox5/NF‐κB pathway
Jianghua Cheng, Wenjing Zhang, Junfeng Zhu et al. (12 authors)
International Journal of Laboratory Hematology
Published: Dec 2020
14 citations
14 citations
1445 days before retraction
A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors
Kai‐Cheng Hsu, Wei‐Chun HuangFu, Tony Eight Lin et al. (11 authors)
Scientific Reports
Open Access
Published: Jun 2020
9 citations
9 citations
1624 days before retraction
Zileuton™ loaded in polymer micelles effectively reduce breast cancer circulating tumor cells and intratumoral cancer stem cells
Petra Gener, Sara Montero‐Herradón, Helena Xandri‐Monje et al. (14 authors)
Nanomedicine Nanotechnology Biology and Medicine
Open Access
Published: Oct 2019
58 citations
58 citations
1870 days before retraction
Zileuton, a 5-Lipoxygenase Inhibitor, Exerts Anti-Angiogenic Effect by Inducing Apoptosis of HUVEC via BK Channel Activation
Hyun-Joung Lim, Jinbong Park, Jae‐Young Um et al. (5 authors)
Cells
Open Access
Published: Sep 2019
14 citations
14 citations
1897 days before retraction
A novel class of tyrosine derivatives as dual 5-LOX and COX-2/mPGES1 inhibitors with PGE<sub>2</sub> mediated anticancer properties
A. Puratchikody, A. Umamaheswari, Irfan Navabshan et al. (8 authors)
New Journal of Chemistry
Published: Dec 2018
15 citations
15 citations
2197 days before retraction
Zileuton suppresses cholangiocarcinoma cell proliferation and migration through inhibition of the Akt signaling pathway
Sasikamon Khophai, Malinee Thanee, Anchalee Techasen et al. (9 authors)
OncoTargets and Therapy
Open Access
Published: Oct 2018
21 citations
21 citations
2261 days before retraction
5-Lipoxygenase: Its involvement in gastrointestinal malignancies
Neha Merchant, L.V.K.S. Bhaskar, Saimila Momin et al. (6 authors)
Critical Reviews in Oncology/Hematology
Published: May 2018
35 citations
35 citations
2397 days before retraction
The role of the lipidome in obesity-mediated colon cancer risk
Raghav Jain, C. Austin Pickens, Jenifer I. Fenton
The Journal of Nutritional Biochemistry
Published: Mar 2018
23 citations
23 citations
2474 days before retraction
Inhibition of 5-lipoxygenase represses neutrophils activation and activates apoptosis in pancreatic tissues during acute necrotizing pancreatitis
Dan Liao, Bo Qian, Yefei Zhang et al. (5 authors)
Biochemical and Biophysical Research Communications
Published: Feb 2018
7 citations
7 citations
2499 days before retraction
Hydroxyeicosatetraenoic acids in patients with pancreatic cancer: a preliminary report.
Tomasz Bodnarczuk, Anna Deskur, Katarzyna Dołęgowska et al. (6 authors)
PubMed
Published: Jan 2018
8 citations
8 citations
2534 days before retraction
Inhibition of 5-lipoxygenase inhibitor zileuton in high-fat diet-induced nonalcoholic fatty liver disease progression model.
Kuifen Ma, Yihe Chen, Xingguang Liang et al. (5 authors)
DOAJ (DOAJ: Directory of Open Access Journals)
Published: Nov 2017
14 citations
14 citations
2595 days before retraction
Inhibition of 5-lipoxygenase alleviates graft-versus-host disease
Bárbara Maximino Rezende, Rayssa M. Athayde, William Antônio Gonçalves et al. (14 authors)
The Journal of Experimental Medicine
Open Access
Published: Sep 2017
19 citations
19 citations
2632 days before retraction
Cysteinyl Leukotriene Receptor Antagonists Inhibit Migration, Invasion, and Expression of MMP-2/9 in Human Glioblastoma
Pannaree Piromkraipak, Kant Sangpairoj, Wuttipong Tirakotai et al. (8 authors)
Cellular and Molecular Neurobiology
Published: Jun 2017
30 citations
30 citations
2740 days before retraction
ALOX5 exhibits anti-tumor and drug-sensitizing effects in MLL-rearranged leukemia
Yungui Wang, Jennifer R. Skibbe, Chao Hu et al. (14 authors)
Scientific Reports
Open Access
Published: May 2017
39 citations
39 citations
2772 days before retraction
Targeting Arachidonic Acid Pathway-Associated NF-κB in Pancreatic Cancer
Nagendra Sastry Yarla, Olga Sukocheva, Ilaria Peluso et al. (18 authors)
Springer eBooks
Published: Jan 2017
2 citations
2 citations
2899 days before retraction
Pancreatic stellate cell: Pandora's box for pancreatic disease biology
Ratnakar R. Bynigeri, Aparna Jakkampudi, Ramaiah Jangala et al. (8 authors)
World Journal of Gastroenterology
Open Access
Published: Jan 2017
162 citations
162 citations
2899 days before retraction
Paper citing Inhibition of 5-lipoxygenase triggers apoptosis in...
Unknown Authors
Unknown Journal
Published: Apr 2016
3155 days before retraction
Microarray-based gene expression profiling reveals genes and pathways involved in the oncogenic function of REG3A on pancreatic cancer cells
Qianqian Xu, Rong Fu, Guoxiao Yin et al. (6 authors)
Gene
Published: Dec 2015
24 citations
24 citations
3276 days before retraction
Quick Stats
Total Citations:
43
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 24, 2025