Retraction

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

Paper Information

Record ID:
64366
Publication Date:
November 21, 2012
Retraction Date:
March 12, 2025 (<1 year years ago)
Subjects:
Article Type:
Publisher:
Society for Neuroscience
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:

Retraction Details

Nature of Retraction:

Retraction

Additional Notes:

see also: https://pubpeer.com/publications/841806329CBD4CD2593E83C5E369EA

Citations (273)

273
Total Citations
2
Post-Retraction
(0.7%)
271
Pre-Retraction
0
Same Day
Post-Retraction Citation Analysis
0 Within 30 days
2 Within 1 year
0 After 2+ years
63 Days since retraction (latest)
Fyn-dependent Tau microcluster formation seeds and boosts extensive Tau pathology
Yingjie Li, Weipeng Qi, Le Chen et al. (10 authors)
Acta Neuropathologica
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63 days after retraction
Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer’s disease: a multi-tracer PET study
Elaheh Salardini, Ryan S. O’Dell, Em Tchorz et al. (8 authors)
Alzheimer s Research & Therapy Open Access
Published: May 2025
55 days after retraction
Amyloid-beta pathology increases synaptic engulfment by glia in feline cognitive dysfunction syndrome: A naturally occurring model of Alzheimer's disease
Robert I McGeachan, Lucy Ewbank, Makayla Watt et al. (12 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Mar 2025
2 days before retraction
Cellular Prion Protein and Amyloid-β Oligomers in Alzheimer’s Disease—Are There Connections?
Michał Fułek, Naomi Hachiya, Martyna Gachowska et al. (12 authors)
International Journal of Molecular Sciences Open Access
Published: Feb 2025
2 citations
13 days before retraction
Identifying the Copper Coordination Environment Between Interacting Neurodegenerative Proteins: A New Approach Using Pulsed EPR with 14N/15N Isotopic Labelling
Amanda Smart, Kevin Singewald, Zikri Hasanbasri et al. (5 authors)
Journal of Biological Chemistry Open Access
Published: Feb 2025
1 citation
39 days before retraction
The Cellular Prion Protein as Universal Receptor for Amyloid Proteins
Luigi Celauro, Giuseppe Legname
˜The œReceptors
Published: Jan 2025
70 days before retraction
Uncovering atrophy progression pattern and mechanisms in individuals at risk of Alzheimer's disease
Christina Tremblay, Shady Rahayel, Alexandre Pastor‐Bernier et al. (100 authors)
Brain Communications Open Access
Published: Jan 2025
70 days before retraction
Fyn, an important molecule in the brain, is a potential therapeutic target for brain tumours
Chongxi Xu, Yi Tang, Xing Lu et al. (4 authors)
Frontiers in Pharmacology Open Access
Published: Dec 2024
98 days before retraction
Biomarkers of Synaptic Degeneration in Alzheimer’s Disease
Qian Cheng, Yiou Fan, Pengfei Zhang et al. (9 authors)
Ageing Research Reviews
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4 citations
101 days before retraction
Identifying the Copper Coordination Environment Between Interacting Neurodegenerative Proteins: A New Approach Using Pulsed EPR with<sup>14</sup>N/<sup>15</sup>N Isotopic Labelling
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bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Nov 2024
117 days before retraction
Pharmacology, Signaling and Therapeutic Potential of Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators
Janko Kos, Monica Langiu, Shane D. Hellyer et al. (4 authors)
ACS Pharmacology & Translational Science Open Access
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2 citations
127 days before retraction
Assessment of the relationship between synaptic density and metabotropic glutamate receptors in early Alzheimer's disease: a multi-tracer PET study
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bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Sep 2024
169 days before retraction
Cellular prion protein acts as mediator of amyloid beta uptake by caveolin‐1 causing cellular dysfunctions in vitro and in vivo
Angela da Silva Correia, Matthias Schmitz, Anna‐Lisa Fischer et al. (11 authors)
Alzheimer s & Dementia Open Access
Published: Aug 2024
8 citations
194 days before retraction
Fyn Kinase in Alzheimer’s Disease: Unraveling Molecular Mechanisms and Therapeutic Implications
Shreyasi Meur, Dipanjan Karati
Molecular Neurobiology
Published: Jun 2024
10 citations
267 days before retraction
Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment
Jie Wang, Qi Huang, Kun He et al. (16 authors)
Alzheimer s & Dementia Open Access
Published: Apr 2024
13 citations
328 days before retraction
What Are the Roles of Cellular Prion Protein in Normal and Pathologic Conditions?
Eduardo E. Benarroch
Neurology
Published: Mar 2024
3 citations
363 days before retraction
Pattern and mechanisms of atrophy progression in individuals with a family history of Alzheimer’s disease: a comparative study
Christina Tremblay, Shady Rahayel, Alexandre Pastor‐Bernier et al. (11 authors)
medRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Mar 2024
1 citation
375 days before retraction
Upregulation of the Proto-Oncogene Src Kinase in Alzheimer’s Disease: From Molecular Interactions to Therapeutic Potential
Diego Mastroeni, Chun Kit Chan, Nader Morshed et al. (19 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Feb 2024
397 days before retraction
Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer’s disease: A [18F]PSS232 PET/MRI study
Jie Wang, Yingfang He, Xing Chen et al. (15 authors)
Alzheimer s Research & Therapy Open Access
Published: Jan 2024
14 citations
425 days before retraction
Cellular prion protein in Alzheimer’s disease: Molecular insights and behavior implications
Angela Patricia Da Silva Correia
Unknown Journal Open Access
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436 days before retraction
Aging-Dependent Loss of Connectivity in Alzheimer’s Model Mice with Rescue by mGluR5 Modulator
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bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Dec 2023
1 citation
452 days before retraction
Evidence supportive of a bacterial component in the etiology for Alzheimer’s disease and for a temporal-spatial development of a pathogenic microbiome in the brain
Yves Moné, Joshua P. Earl, Jarosław E. Król et al. (7 authors)
Frontiers in Cellular and Infection Microbiology Open Access
Published: Sep 2023
20 citations
546 days before retraction
The role of PrPc in Alzheimer's disease related Amyloid-β hypothesis: a systematic review
Tomás Andrade Magalhães Gomes, Marcos Paulo dos Santos Silva, Matheus Proença Simão Magalhães Gomes et al. (6 authors)
Brain Disorders Open Access
Published: Sep 2023
558 days before retraction
Maladie d’Alzheimer, peptides β-amyloïdes et système ubiquitine-protéasome
P Simon, Johanna Bus, R. David
médecine/sciences Open Access
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589 days before retraction
The Deficits of Insulin Signal in Alzheimer’s Disease and the Mechanisms of Vanadium Compounds in Curing AD
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Current Issues in Molecular Biology Open Access
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4 citations
590 days before retraction
Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
Yun Zhang, Huaqiu Chen, Ran Li et al. (5 authors)
Signal Transduction and Targeted Therapy Open Access
Published: Jun 2023
455 citations
621 days before retraction
Peptide aptamer targeting Aβ–PrP–Fyn axis reduces Alzheimer’s disease pathologies in 5XFAD transgenic mouse model
Tahir Ali, Antonia Klein, Alex P. Vu et al. (6 authors)
Cellular and Molecular Life Sciences Open Access
Published: May 2023
8 citations
675 days before retraction
Mycoplasma fermentans infection induces human necrotic neuronal cell death via IFITM3-mediated amyloid-β (1–42) deposition
Kyu-Young Sim, Yeongseon Byeon, So-Eun Bae et al. (6 authors)
Scientific Reports Open Access
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1 citation
686 days before retraction
Imbalance of Essential Metals in Traumatic Brain Injury and Its Possible Link with Disorders of Consciousness
Rosanna Squitti, Giuseppe Reale, Vincenzo Tondolo et al. (9 authors)
International Journal of Molecular Sciences Open Access
Published: Apr 2023
17 citations
706 days before retraction
Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates
K. Sandeep, Roopali Khanna, Anamika Avni et al. (4 authors)
Proceedings of the National Academy of Sciences Open Access
Published: Jan 2023
49 citations
799 days before retraction
Insoluble Cellular Prion Protein and Other Neurodegeneration-Related Protein Aggregates in the Brain of Asymptomatic Individuals
Wen‐Quan Zou
Springer eBooks
Published: Jan 2023
1 citation
801 days before retraction
Human prion diseases and the prion protein – what is the current state of knowledge?
Reinhold Nafe, Christophe Arendt, Elke Hattingen
Translational Neuroscience Open Access
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15 citations
801 days before retraction
Synaptic degeneration in Alzheimer disease
Makis Tzioras, Robert I McGeachan, Claire S. Durrant et al. (4 authors)
Nature Reviews Neurology
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285 citations
820 days before retraction
The role of d-block metal ions in neurodegenerative diseases
Yanahi Posadas, Víctor E. López-Guerrero, Trinidad Arcos‐López et al. (8 authors)
Elsevier eBooks
Published: Oct 2022
2 citations
876 days before retraction
Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates
K. Sandeep, Roopali Khanna, Anamika Avni et al. (4 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Sep 2022
907 days before retraction
Single domain antibodies targeting pathological tau protein: Influence of four IgG subclasses on efficacy and toxicity
Erin E. Congdon, Ruimin Pan, Yixiang Jiang et al. (10 authors)
EBioMedicine Open Access
Published: Sep 2022
25 citations
914 days before retraction
The multiple functions of PrPC in physiological, cancer, and neurodegenerative contexts
Izabella Grimaldi, Felipe Saceanu Leser, José Marcos Janeiro et al. (7 authors)
Journal of Molecular Medicine
Published: Sep 2022
11 citations
921 days before retraction
Evidence for the Existence of a Bacterial Etiology for Alzheimer’s Disease and for a Temporal-Spatial Development of a Pathogenic Microbiome in the Brain
Yves Moné, Joshua P. Earl, Jarosław E. Król et al. (7 authors)
bioRxiv (Cold Spring Harbor Laboratory) Open Access
Published: Aug 2022
1 citation
926 days before retraction
Amyloid precursor protein (APP) and amyloid β (Aβ) interact with cell adhesion molecules: Implications in Alzheimer’s disease and normal physiology
Grant Pfundstein, Alexander G. Nikonenko, Vladimir Sytnyk
Frontiers in Cell and Developmental Biology Open Access
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51 citations
960 days before retraction
Amyloid Beta Peptide-Mediated Alterations in Mitochondrial Dynamics and its Implications for Alzheimer’s Disease
Luis Ángel Monsalvo-Maraver, Marisol Maya-López, Edgar Rangel‐López et al. (9 authors)
CNS & Neurological Disorders - Drug Targets
Published: Jun 2022
5 citations
999 days before retraction
Reversal of synapse loss in Alzheimer mouse models by targeting mGluR5 to prevent synaptic tagging by C1Q
Joshua Spurrier, LaShae Nicholson, Xiaotian T. Fang et al. (22 authors)
Science Translational Medicine Open Access
Published: Jun 2022
74 citations
1015 days before retraction
The synapse as a treatment avenue for Alzheimer’s Disease
Lin Peng, Isabel Bestard‐Lorigados, Weihong Song
Molecular Psychiatry
Published: Apr 2022
105 citations
1057 days before retraction
Differential vulnerability of hippocampal CA3-CA1 synapses to Aβ
Olivia A. Shipton, Clara S. Tang, Ole Paulsen et al. (4 authors)
Acta Neuropathologica Communications Open Access
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10 citations
1073 days before retraction
A Bioinformatics Approach Toward Unravelling the Synaptic Molecular Crosstalk Between Alzheimer’s Disease and Diabetes
Steven R. Alves, Cristóvão da Cruz e Silva, Ilka Martins Rosa et al. (5 authors)
Journal of Alzheimer s Disease Open Access
Published: Mar 2022
6 citations
1104 days before retraction
Antroquinonol administration in animal preclinical studies for Alzheimer's disease (AD): A new avenue for modifying progression of AD pathophysiology
Francesca Fernandez, Caitlin E. Aust, Sarah Lye et al. (4 authors)
Brain Behavior & Immunity - Health Open Access
Published: Feb 2022
7 citations
1112 days before retraction
The prion protein and its ligands: Insights into structure-function relationships
Mohsin Shafiq, Stefano Da Vela, Ladan Amin et al. (9 authors)
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Open Access
Published: Feb 2022
15 citations
1117 days before retraction
The Src-Kinase Fyn is Required for Cocaine-Associated Memory Through Regulation of Tau
Hong‐Chun Li, Xinglong Zhou, Rong Chen et al. (5 authors)
Frontiers in Pharmacology Open Access
Published: Feb 2022
1 citation
1133 days before retraction
Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein
Behnam Mohammadi, Feizhi Song, Andreu Matamoros‐Angles et al. (8 authors)
Cell and Tissue Research Open Access
Published: Jan 2022
11 citations
1140 days before retraction
Quick Stats
Total Citations: 273
Years Since Retraction: <1 year
Open Access: Yes
Last Checked: Jul 23, 2025