Retraction

The complex PrP(c)-Fyn couples human oligomeric Aβ with pathological tau changes in Alzheimer's disease

Paper Information

Record ID:
64366
Publication Date:
November 21, 2012
Retraction Date:
March 12, 2025 (<1 year years ago)
Subjects:
Article Type:
Publisher:
Society for Neuroscience
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:

Retraction Details

Nature of Retraction:

Retraction

Additional Notes:

see also: https://pubpeer.com/publications/841806329CBD4CD2593E83C5E369EA

Citations (273)

273
Total Citations
2
Post-Retraction
(0.7%)
271
Pre-Retraction
0
Same Day
Post-Retraction Citation Analysis
0 Within 30 days
2 Within 1 year
0 After 2+ years
63 Days since retraction (latest)
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The Essential Role of Soluble Aβ Oligomers in Alzheimer’s Disease
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Tau Immunotherapy Modulates Both Pathological Tau and Upstream Amyloid Pathology in an Alzheimer's Disease Mouse Model
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Paper citing The complex PrP(c)-Fyn couples human oligomeric Aβ...
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The sheddase ADAM10 is a potent modulator of prion disease
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eLife Open Access
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83 citations
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Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP
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Frontiers in Cell and Developmental Biology Open Access
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10 citations
3709 days before retraction
Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines
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87 citations
3721 days before retraction
Functional implications of tau-fyn interactions in Alzheimer's disease
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Unknown Journal
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3723 days before retraction
Drug Repositioning Approaches for the Discovery of New Therapeutics for Alzheimer's Disease
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Toxic oligomer species of amyloid-β in Alzheimer's disease, a timing issue
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Schweizerische medizinische Wochenschrift Open Access
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Single‐Molecule Imaging Reveals that Small Amyloid‐β<sub>1–42</sub> Oligomers Interact with the Cellular Prion Protein (PrP<sup>C</sup>)
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ChemBioChem Open Access
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45 citations
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AlphaScreen HTS and Live-Cell Bioluminescence Resonance Energy Transfer (BRET) Assays for Identification of Tau–Fyn SH3 Interaction Inhibitors for Alzheimer Disease
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SLAS DISCOVERY Open Access
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Therapeutic Molecules and Endogenous Ligands Regulate the Interaction between Brain Cellular Prion Protein (PrPC) and Metabotropic Glutamate Receptor 5 (mGluR5)
Laura T. Haas, Mikhail A. Kostylev, Stephen M. Strittmatter
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78 citations
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Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease
Nicole T. Watt, Heledd Jarosz-Griffiths, Nigel M. Hooper
Frontiers in Cell and Developmental Biology Open Access
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19 citations
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Advances in Therapeutics for Neurodegenerative Tauopathies: Moving toward the Specific Targeting of the Most Toxic Tau Species
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ACS Chemical Neuroscience
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68 citations
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Targeting the proper amyloid-beta neuronal toxins: a path forward for Alzheimer’s disease immunotherapeutics
William F. Goure, Grant A. Krafft, Jasna Jerecı̀ć et al. (4 authors)
Alzheimer s Research & Therapy Open Access
Published: Jul 2014
170 citations
3899 days before retraction
Role of PrPC Expression in Tau Protein Levels and Phosphorylation in Alzheimer’s Disease Evolution
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Molecular Neurobiology Open Access
Published: Jun 2014
39 citations
3913 days before retraction
Di-Tyrosine Cross-Link Decreases the Collisional Cross-Section of Aβ Peptide Dimers and Trimers in the Gas Phase: An Ion Mobility Study
Ewa Sitkiewicz, Jacek Olędzki, Jarosław Poznański et al. (4 authors)
PLoS ONE Open Access
Published: Jun 2014
26 citations
3919 days before retraction
PrPC signalling in neurons: From basics to clinical challenges
Théo Z. Hirsch, Julia Hernandez-Rapp, Severine Martin‐Lannerée et al. (5 authors)
Biochimie Open Access
Published: Jun 2014
30 citations
3920 days before retraction
Genetic Modulation of Soluble A Rescues Cognitive and Synaptic Impairment in a Mouse Model of Alzheimer's Disease
Stephanie Fowler, Angie C.A. Chiang, Ricky R. Savjani et al. (9 authors)
Journal of Neuroscience Open Access
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79 citations
3934 days before retraction
Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn
Di Xia, Jà ⁄ rgen Götz
Frontiers in Molecular Neuroscience Open Access
Published: May 2014
26 citations
3956 days before retraction
A PrPC-caveolin-Lyn complex negatively controls neuronal GSK3β and serotonin 1B receptor
Julia Hernandez-Rapp, Severine Martin‐Lannerée, Théo Z. Hirsch et al. (9 authors)
Scientific Reports Open Access
Published: May 2014
29 citations
3961 days before retraction
The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease
Tara L. Spires‐Jones, Bradley T. Hyman
Neuron Open Access
Published: May 2014
1047 citations
3968 days before retraction
Antioxidant and Metal Chelation-Based Therapies in the Treatment of Prion Disease
Marcus W. Brazier, Anthony G. Wedd, Steven Collins
Antioxidants Open Access
Published: Apr 2014
13 citations
3978 days before retraction
Translation of the Prion Protein mRNA Is Robust in Astrocytes but Does Not Amplify during Reactive Astrocytosis in the Mouse Brain
Walker S. Jackson, Clemens Krost, Andrew W. Borkowski et al. (4 authors)
PLoS ONE Open Access
Published: Apr 2014
12 citations
3978 days before retraction
Involvement of ‘stress–response’ kinase pathways in Alzheimer's disease progression
Georges Mairet‐Coello, Franck Polleux
Current Opinion in Neurobiology Open Access
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13 citations
3994 days before retraction
Tau acts as a mediator for <scp>A</scp>lzheimer's disease‐related synaptic deficits
Dezhi Liao, Eric C. Miller, Peter J. Teravskis
European Journal of Neuroscience Open Access
Published: Apr 2014
47 citations
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Biochemical Distribution of Tau Protein in Synaptosomal Fraction of Transgenic Mice Expressing Human P301L Tau
Naruhiko Sahara, Miyuki Murayama, Makoto Higuchi et al. (5 authors)
Frontiers in Neurology Open Access
Published: Mar 2014
38 citations
4019 days before retraction
Loss of Prion Protein Leads to Age-Dependent Behavioral Abnormalities and Changes in Cytoskeletal Protein Expression
Matthias Schmitz, Catharina Marlies Greis, Philipp Ottis et al. (13 authors)
Molecular Neurobiology
Published: Mar 2014
40 citations
4024 days before retraction
mGlu5 receptors and cellular prion protein mediate amyloid-β-facilitated synaptic long-term depression in vivo
Neng‐Wei Hu, Andrew J. Nicoll, Dainan Zhang et al. (10 authors)
Nature Communications Open Access
Published: Mar 2014
169 citations
4026 days before retraction
Prions and Prion-Like Pathogens in Neurodegenerative Disorders
Caterina Peggion, Maria Catia Sorgato, Alessandro Bertoli
Pathogens Open Access
Published: Feb 2014
17 citations
4040 days before retraction
Hyperphosphorylated Tau is Elevated in Alzheimer's Disease with Psychosis
Patrick S. Murray, Caitlin M. Kirkwood, Megan C. Gray et al. (10 authors)
Journal of Alzheimer s Disease Open Access
Published: Feb 2014
61 citations
4044 days before retraction
High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer’s disease
Frank Dohler, Diego Sepúlveda‐Falla, Susanne Krasemann et al. (9 authors)
Brain
Published: Feb 2014
104 citations
4048 days before retraction
Reciprocal disruption of neuronal signaling and Aβ production mediated by extrasynaptic NMDA receptors: a downward spiral
Travis Rush, Alain Buisson
Cell and Tissue Research
Published: Feb 2014
41 citations
4054 days before retraction
Des maladies à prions à la maladie d’Alzheimer
Mathéa Pietri, Aurélie Alleaume-Butaux, Jean‐Marie Launay et al. (5 authors)
médecine/sciences Open Access
Published: Feb 2014
4057 days before retraction
Mapping It out: A Novel Signaling Pathway Linking Aβ-PrP&amp;lt;sup&amp;gt;c&amp;lt;/sup&amp;gt;-Fyn Complex to Cognitive Impairment in Alzheimer’s Disease
Yiling Wang, Lei Xue
Advances in Alzheimer s Disease Open Access
Published: Jan 2014
4088 days before retraction
New light on prions: putative role of co-operation of PrPc and Aβ proteins in cognition
Adrian Andrzej Chrobak, Dariusz Adamek
Folia Neuropathologica Open Access
Published: Jan 2014
5 citations
4088 days before retraction
Fyn kinase inhibition as a novel therapy for Alzheimer’s disease
Haakon B. Nygaard, Christopher H. van Dyck, Stephen M. Strittmatter
Alzheimer s Research & Therapy Open Access
Published: Jan 2014
188 citations
4088 days before retraction
Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein
Walker S. Jackson
Disease Models & Mechanisms Open Access
Published: Jan 2014
96 citations
4088 days before retraction
Hijacking PrPc-dependent signal transduction: when prions impair Aβ clearance
Julia Hernandez-Rapp, Severine Martin‐Lannerée, Théo Z. Hirsch et al. (5 authors)
Frontiers in Aging Neuroscience Open Access
Published: Jan 2014
20 citations
4088 days before retraction
Proteostasis and Secondary Proteinopathy in Alzheimer?s Disease
David R. Borchelt Guilian Xu, Lucia Notterpek Jada Lewis
Journal of Alzheimer’s Disease & Parkinsonism Open Access
Published: Jan 2014
9 citations
4088 days before retraction
The dendritic hypothesis for Alzheimer's disease pathophysiology
J. Nicholas Cochran, Alicia M. Hall, Erik D. Roberson
Brain Research Bulletin Open Access
Published: Dec 2013
111 citations
4108 days before retraction
Impact of the Cellular Prion Protein on Amyloid-β and 3PO-Tau Processing
Matthias Schmitz, Katharina Wulf, Sandra C. Signore et al. (9 authors)
Journal of Alzheimer s Disease Open Access
Published: Nov 2013
26 citations
4125 days before retraction
Quick Stats
Total Citations: 273
Years Since Retraction: <1 year
Open Access: Yes
Last Checked: Jul 23, 2025