Retraction

Enriched environment prevents hypobaric hypoxia induced memory impairment and neurodegeneration: role of BDNF/PI3K/GSK3β pathway coupled with CREB activation

Paper Information

Record ID:
64369
Author(s):
Vishal Jain
Iswar Baitharu
Dipti Prasad
Govindasamy Ilavazhagan
Journal:
PLoS One ( PLoS )
Publication Date:
May 21, 2013
Retraction Date:
January 09, 2025 (<1 year years ago)
Subjects:
Broad Categories:
Neuroscience Environmental Sciences Genetics Biology Medicine
Institutions:
Country:
🇮🇳 India
Article Type:
Research Article
Publisher:
PLoS
Open Access:
Yes
DOI:
10.1371/journal.pone.0062235
PubMed ID:
23704876
Retraction PubMed ID:
39787205

Retraction Details

Retraction Reasons:
Nature of Retraction:

Retraction

Retraction Notice:
10.1371/journal.pone.0317531

Citations (84)

84
Total Citations
1
Post-Retraction
(1.2%)
82
Pre-Retraction
1
Same Day
Post-Retraction Citation Analysis
1 Within 30 days
1 Within 1 year
0 After 2+ years
1 Days since retraction (latest)
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Retraction: Enriched Environment Prevents Hypobaric Hypoxia Induced Memory Impairment and Neurodegeneration: Role of BDNF/PI3K/GSK3β Pathway Coupled with CREB Activation
Unknown Authors
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Exploring Effects of the HEP (Homeostasis-Enrichment-Plasticity) Approach as a Comprehensive Therapy Intervention for an Infant with Cerebral Palsy: A Case Report
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Ginkgo biloba L. Prevents Hypobaric Hypoxia–Induced Spatial Memory Deficit Through Small Conductance Calcium-Activated Potassium Channel Inhibition: The Role of ERK/CaMKII/CREB Signaling
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1322 days before retraction
Co-treatment of vitamin D supplementation with enriched environment improves synaptic plasticity and spatial learning and memory in aged rats
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Psychopharmacology
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16 citations
1335 days before retraction
HDAC inhibition prevents hypobaric hypoxia‐induced spatial memory impairment through PΙ3K/GSK3β/CREB pathway
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Journal of Cellular Physiology
Published: Mar 2021
13 citations
1380 days before retraction
Elucidating the role of hypoxia/reoxygenation in hippocampus-dependent memory impairment: do SK channels play role?
Manisha Kadam, Saba Perveen, Neetu Kushwah et al. (7 authors)
Experimental Brain Research
Published: Mar 2021
4 citations
1382 days before retraction
Environmental Enrichment Improved Cognitive Performance in Mice under Normoxia and Hypoxia
Sahej Bindra, Joseph C. LaManna, Kui Xu
Advances in experimental medicine and biology
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6 citations
1469 days before retraction
Effects of datumetine on hippocampal NMDAR activity
Azeez Olakunle Ishola, Aminu Imam, Moyosore Salihu Ajao
Toxicology Reports Open Access
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7 citations
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Chronic Stress Weakens Connectivity in the Prefrontal Cortex: Architectural and Molecular Changes
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Chronic Stress Open Access
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Molecular Mechanism of Platelet-Derived Growth Factor (PDGF)-BB-Mediated Protection Against MPP+ Toxicity in SH-SY5Y Cells
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Neurobiology of Disease Open Access
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44 citations
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The delicate balance between neurotoxicity and neuroprotection in the context of <scp>HIV</scp>‐1 infection
Vincent Sénécal, Corinne Barat, Michel J. Tremblay
Glia
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10 citations
1582 days before retraction
Fear memory is impaired in hypobaric hypoxia: Role of synaptic plasticity and neuro-modulators in limbic region
Punita Kumari, Koustav Roy, Meetu Wadhwa et al. (8 authors)
Life Sciences
Published: Mar 2020
18 citations
1760 days before retraction
Cornel iridoid glycoside ameliorates cognitive deficits in APP/PS1/tau triple transgenic mice by attenuating amyloid-beta, tau hyperphosphorylation and neurotrophic dysfunction
Cuicui Yang, Xunjie Bao, Li Zhang et al. (6 authors)
Annals of Translational Medicine Open Access
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17 citations
1775 days before retraction
Cornel iridoid glycoside improves cognitive impairment induced by chronic cerebral hypoperfusion via activating PI3K/Akt/GSK-3β/CREB pathway in rats
Mingyang Wang, Min Meng, Cuicui Yang et al. (7 authors)
Behavioural Brain Research
Published: Oct 2019
20 citations
1904 days before retraction
Annona atemoya Leaf Extract Improves Scopolamine-Induced Memory Impairment by Preventing Hippocampal Cholinergic Dysfunction and Neuronal Cell Death
Eunjin Sohn, Hye-Sun Lim, Yu Jin Kim et al. (5 authors)
International Journal of Molecular Sciences Open Access
Published: Jul 2019
25 citations
2001 days before retraction
Environmental enrichment restores the reduced expression of cerebellar synaptophysin and the motor coordination impairment in rats prenatally treated with betamethasone
Martina Valencia, Javiera Illanes, Odra Santander et al. (8 authors)
Physiology & Behavior
Published: Jun 2019
9 citations
2025 days before retraction
Adenosine N1-Oxide Exerts Anti-inflammatory Effects through the PI3K/Akt/GSK-3β Signaling Pathway and Promotes Osteogenic and Adipocyte Differentiation
Emiko Ohashi, Keizo Kohno, Norie Arai et al. (6 authors)
Biological and Pharmaceutical Bulletin Open Access
Published: May 2019
26 citations
2050 days before retraction
Brain-derived neurotrophic factor induces thioredoxin-1 expression through TrkB/Akt/CREB pathway in SH-SY5Y cells
Liping Bai, Se Zhang, Xiaoshuang Zhou et al. (5 authors)
Biochimie
Published: Feb 2019
38 citations
2150 days before retraction
Housing and road transport modify the brain neurotransmitter systems of pigs: Do pigs raised in different conditions cope differently with unknown environments?
Laura Arroyo, Daniel Valent, Ricard Carreras et al. (7 authors)
PLoS ONE Open Access
Published: Jan 2019
9 citations
2185 days before retraction
Maternal Protein Malnutrition: Current and Future Perspectives of Spirulina Supplementation in Neuroprotection
Shrstha Sinha, Nisha Patro, Ishan Patro
Frontiers in Neuroscience Open Access
Published: Dec 2018
35 citations
2214 days before retraction
Hypoxia-mediated alteration in cholesterol oxidation and raft dynamics regulates BDNF signalling and neurodegeneration in hippocampus
Deepti Sharma, Kalpana Barhwal, Suryanarayan Biswal et al. (8 authors)
Journal of Neurochemistry Open Access
Published: Oct 2018
23 citations
2282 days before retraction
Kaempferol Inhibits Extra-synaptic NMDAR-Mediated Downregulation of TRkβ in Rat Hippocampus During Hypoxia
Debashree Das, Suryanarayan Biswal, Kalpana Barhwal et al. (5 authors)
Neuroscience
Published: Sep 2018
20 citations
2297 days before retraction
Phosphorylated delta sleep inducing peptide restores spatial memory and p-CREB expression by improving sleep architecture at high altitude
Koustav Roy, Garima Chauhan, Punita Kumari et al. (8 authors)
Life Sciences
Published: Aug 2018
10 citations
2343 days before retraction
Hypobaric Hypoxia-Induced Learning and Memory Impairment: Elucidating the Role of Small Conductance Ca2+-Activated K+ Channels
Neetu Kushwah, Vishal Jain, Aastha Dheer et al. (6 authors)
Neuroscience
Published: Jul 2018
21 citations
2361 days before retraction
Temporal and Spatial Changes in Glial Cells During Chronic Hypobaric Hypoxia: Role in Neurodegeneration
Aastha Dheer, Vishal Jain, Nishita Kushwah et al. (6 authors)
Neuroscience
Published: May 2018
25 citations
2437 days before retraction
Salidroside mediated stabilization of Bcl -xL prevents mitophagy in CA3 hippocampal neurons during hypoxia
Suryanarayan Biswal, Kalpana Barhwal, Debashree Das et al. (7 authors)
Neurobiology of Disease
Published: May 2018
26 citations
2445 days before retraction
Rifampicin Prevents SH-SY5Y Cells from Rotenone-Induced Apoptosis via the PI3K/Akt/GSK-3β/CREB Signaling Pathway
Xia Wu, Yanran Liang, Xiuna Jing et al. (12 authors)
Neurochemical Research
Published: Feb 2018
49 citations
2523 days before retraction
Role of DNA Methylation in Hypobaric Hypoxia-Induced Neurodegeneration and Spatial Memory Impairment
Rahul Kumar, Vishal Jain, Neetu Kushwah et al. (7 authors)
Annals of Neurosciences Open Access
Published: Jan 2018
33 citations
2565 days before retraction
Quick Stats
Total Citations: 84
Years Since Retraction: <1 year
Open Access: Yes
Last Checked: Jul 24, 2025
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