Retraction

Selective molecular alterations in the autophagy pathway in patients with Lewy body disease and in models of alpha-synucleinopathy

Paper Information

Record ID:
64531
Author(s):
Leslie Crews
Brian Spencer
Paula Desplats
Christina Patrick
Amy Paulino
Edward Rockenstein
Lawrence Hansen
Anthony Adame
Douglas Galasko
Eliezer Masliah
Journal:
PLoS One ( PLoS )
Publication Date:
February 19, 2010
Retraction Date:
November 13, 2024 (1.0 year years ago)
Subjects:
Broad Categories:
Neuroscience Biology Medicine Genetics
Institutions:
Country:
🇺🇸 United States
Article Type:
Research Article
Publisher:
PLoS
Open Access:
Yes
DOI:
10.1371/journal.pone.0009313
PubMed ID:
20174468
Retraction PubMed ID:
39536070

Retraction Details

Retraction Reasons:
Nature of Retraction:

Retraction

Retraction Notice:
10.1371/journal.pone.0313935

Citations (365)

365
Total Citations
8
Post-Retraction
(2.2%)
355
Pre-Retraction
1
Same Day
Post-Retraction Citation Analysis
0 Within 30 days
8 Within 1 year
0 After 2+ years
166 Days since retraction (latest)
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102 citations
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Journal of Neuroinflammation Open Access
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34 citations
3095 days before retraction
Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy
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Mechanisms of Ageing and Development Open Access
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Current Neuropharmacology Open Access
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61 citations
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Autophagy and <scp>A</scp>lpha‐<scp>S</scp>ynuclein: <scp>R</scp>elevance to <scp>P</scp>arkinson's <scp>D</scp>isease and <scp>R</scp>elated <scp>S</scp>ynucleopathies
Maria Xilouri, Oeystein Roed Brekk, Leonidas Stefanis
Movement Disorders
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244 citations
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α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease
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Human Molecular Genetics Open Access
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Alpha-synuclein expression influences the processing of the amyloid precursor protein
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Journal of Biological Chemistry Open Access
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58 citations
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Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease
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3274 days before retraction
HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders
Jerel Adam Fields, Elisabeth Serger, S. Sánchez Campos et al. (15 authors)
Neurobiology of Disease Open Access
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94 citations
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The Effects of Prolyl Oligopeptidase Inhibition in α-Synuclein Based Mouse Models of Parkinson's Disease
Mari Savolainen
Unknown Journal
Published: Oct 2015
3302 days before retraction
Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders
Kenneth Maiese
British Journal of Clinical Pharmacology Open Access
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173 citations
3317 days before retraction
A brain-targeted, modified neurosin (kallikrein-6) reduces α-synuclein accumulation in a mouse model of multiple system atrophy
Brian Spencer, Elvira Valera, Edward Rockenstein et al. (6 authors)
Molecular Neurodegeneration Open Access
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41 citations
3339 days before retraction
Deconvoluting the complexity of autophagy and Parkinson's disease for potential therapeutic purpose
Jingjing Li, Sijia Li, Lan Zhang et al. (5 authors)
Oncotarget Open Access
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Combination therapies: The next logical Step for the treatment of synucleinopathies?
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Movement Disorders Open Access
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mTOR in Brain Physiology and Pathologies
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Physiological Reviews
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Structure, function and toxicity of alpha‐synuclein: the Bermuda triangle in synucleinopathies
Anna Villar‐Piqué, Tomás Lopes da Fonseca, Tiago F. Outeiro
Journal of Neurochemistry Open Access
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Rapamycin alleviates pathogenesis of a new<i>Drosophila</i>model of ALS-TDP
Ching‐Wei Cheng, Meng-Jau Lin, Che-Kun James Shen
Journal of Neurogenetics
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57 citations
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Autophagic activity in neuronal cell death
Robert W. Button, Shouqing Luo, David C. Rubinsztein
Neuroscience Bulletin Open Access
Published: Jun 2015
81 citations
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The Interplay between Alpha-Synuclein Clearance and Spreading
Tomás Lopes da Fonseca, Anna Villar‐Piqué, Tiago F. Outeiro
Biomolecules Open Access
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99 citations
3501 days before retraction
Autophagy in neurodegenerative diseases: From pathogenic dysfunction to therapeutic modulation
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Seminars in Cell and Developmental Biology
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Genetic and Chemical Activation of TFEB Mediates Clearance of Aggregated α-Synuclein
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PLoS ONE Open Access
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126 citations
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Active immunization against alpha-synuclein ameliorates the degenerative pathology and prevents demyelination in a model of multiple system atrophy
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Molecular Neurodegeneration Open Access
Published: Mar 2015
142 citations
3528 days before retraction
Mechanisms of HIV-1 Tat Neurotoxicity via CDK5 Translocation and Hyper-Activation: Role in HIV-Associated Neurocognitive Disorders
Jerel Adam Fields, Wilmar Dumaop, Leslie Crews et al. (9 authors)
Current HIV Research Open Access
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53 citations
3529 days before retraction
HIV-1 Tat Alters Neuronal Autophagy by Modulating Autophagosome Fusion to the Lysosome: Implications for HIV-Associated Neurocognitive Disorders
Jerel Adam Fields, Wilmar Dumaop, Simona Elueteri et al. (12 authors)
Journal of Neuroscience Open Access
Published: Feb 2015
121 citations
3570 days before retraction
Lysosomal-associated membrane protein 2 isoforms are differentially affected in early Parkinson's disease
Karen E. Murphy, Amanda M. Gysbers, Sarah K. Abbott et al. (9 authors)
Movement Disorders
Published: Jan 2015
153 citations
3589 days before retraction
Rapamycin improves motor function, reduces 4-hydroxynonenal adducted protein in brain, and attenuates synaptic injury in a mouse model of synucleinopathy
Xiang Bai, Margaret Wey, Elizabeth Fernández et al. (8 authors)
Pathobiology of Aging & Age-related Diseases Open Access
Published: Jan 2015
56 citations
3604 days before retraction
Targeting Unselective Autophagy of Cellular Aggregates
Pierfausto Seneci
Elsevier eBooks
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3604 days before retraction
Autophagy and neurodegeneration
Rebecca A. Frake, Thomas C. Ricketts, Fiona M. Menzies et al. (4 authors)
Journal of Clinical Investigation Open Access
Published: Jan 2015
316 citations
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The link between the SNCA gene and parkinsonism
Wei Xu, Lan Tan, Jin‐Tai Yu
Neurobiology of Aging
Published: Dec 2014
66 citations
3633 days before retraction
Autophagy modulates SNCA/α-synuclein release, thereby generating a hostile microenvironment
Anne-Maria Poehler, Wei Xiang, Philipp Spitzer et al. (11 authors)
Autophagy Open Access
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194 citations
3667 days before retraction
Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases
Haijian Wu, Sheng Chen, Ammar Al-Baadani et al. (8 authors)
Molecular Neurobiology Open Access
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85 citations
3677 days before retraction
Rho Kinase and Dopaminergic Degeneration
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The Neuroscientist
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48 citations
3681 days before retraction
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Molecular Neurobiology
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62 citations
3683 days before retraction
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Kelly A. Meulendyke, Joshua Croteau, M. Christine Zink
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17 citations
3718 days before retraction
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Barry Boland, Frances M. Platt
Best Practice & Research Clinical Endocrinology & Metabolism
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22 citations
3726 days before retraction
Neuroprotective effects of the anti‐cancer drug sunitinib in models of <scp>HIV</scp> neurotoxicity suggests potential for the treatment of neurodegenerative disorders
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British Journal of Pharmacology Open Access
Published: Aug 2014
26 citations
3745 days before retraction
Taking aim at Alzheimer's disease through the mammalian target of rapamycin
Kenneth Maiese
Annals of Medicine Open Access
Published: Aug 2014
75 citations
3750 days before retraction
Quick Stats
Total Citations: 365
Years Since Retraction: 1.0 year
Open Access: Yes
Last Checked: Jul 24, 2025
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