Retraction
Nitric Oxide Induces Hypoxia-inducible Factor 1 Activation That Is Dependent on MAPK and Phosphatidylinositol 3-Kinase Signaling
Paper Information
Record ID:
66062
Author(s):
Journal:
Publication Date:
November 04, 2003
Retraction Date:
July 05, 2025
(<1 year years ago)
Subjects:
Institutions:
- Human Stress Signal Research Center, National Institute of Advanced Industrial Science and Technology, IKEDA, Osaka, Japan 563-0053
- Department of Anesthesia, Tazuke Kofukai Medical Research Institute Kitano Hospital, 2-4-20, Ohgimachi, Kita-ku, Osaka 530-8480
- Institute for Virus Research, Kyoto University Hospital, Kyoto University, Kyoto 606-8507, Japan
- Department of Anesthesia, Kyoto University Hospital, Kyoto University, Kyoto 606-8507, Japan
- Department of Molecular Oncology, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto 606-8507, Japan
- McKusick-Nathans Institute of Genetic Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287
Countries:
Article Type:
Publisher:
Elsevier
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (230)
230
Total Citations0
Post-Retraction228
Pre-Retraction0
Same DayPaper citing Nitric Oxide Induces Hypoxia-inducible Factor 1 Ac...
Unknown Authors
Unknown Journal
Published: Oct 2008
6107 days before retraction
Ang-1 Gene Therapy Inhibits Hypoxia-Inducible Factor-1α (HIF-1α)-Prolyl-4-Hydroxylase-2, Stabilizes HIF-1α Expression, and Normalizes Immature Vasculature in <i>db</i>/<i>db</i> Mice
Jian‐Xiong Chen, Amanda Stinnett
Diabetes
Open Access
Published: Oct 2008
79 citations
79 citations
6118 days before retraction
Mitochondrial dysfunction and HIF1α stabilization in inflammation
Assegid Garedew, Salvador Moncada
Journal of Cell Science
Published: Oct 2008
29 citations
29 citations
6121 days before retraction
Redox Regulation of Cell Survival
Dunyaporn Trachootham, Weiqin Lu, Marcia A. Ogasawara et al. (5 authors)
Antioxidants and Redox Signaling
Open Access
Published: Jun 2008
1691 citations
1691 citations
6241 days before retraction
Novel Dioxygenases, HIF-α Specific Prolyl-hydroxylase and Asparanginyl-hydroxylase: O<sub>2</sub> Switch for Cell Survival
Hyunsung Park
Toxicological Research
Open Access
Published: Jun 2008
2 citations
2 citations
6243 days before retraction
Causes and Consequences of Increased Glucose Metabolism of Cancers
Robert J. Gillies, Ian Robey, Robert A. Gatenby
Journal of Nuclear Medicine
Open Access
Published: Jun 2008
623 citations
623 citations
6243 days before retraction
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Mark W. Dewhirst, Yiting Cao, Benjamin J. Moeller
Nature reviews. Cancer
Open Access
Published: May 2008
990 citations
990 citations
6252 days before retraction
Macrophage Migration Inhibitory Factor Activates Hypoxia-Inducible Factor in a p53-Dependent Manner
Seiko Oda, Tomoyuki Oda, Kenichiro Nishi et al. (10 authors)
PLoS ONE
Open Access
Published: May 2008
125 citations
125 citations
6254 days before retraction
Nitric oxide, apoptosis and macrophage polarization during tumor progression
Andreas Weigert, Bernhard Brüne
Nitric Oxide
Published: Apr 2008
142 citations
142 citations
6275 days before retraction
Nitric Oxide Donor, (±)-<i>S</i>-Nitroso-<i>N</i>-acetylpenicillamine, Stabilizes Transactive Hypoxia-Inducible Factor-1α by Inhibiting von Hippel-Lindau Recruitment and Asparagine Hydroxylation
Young-Kwon Park, Dae‐Ro Ahn, Myoungsuk Oh et al. (7 authors)
Molecular Pharmacology
Published: Apr 2008
53 citations
53 citations
6284 days before retraction
Inflammatory Levels of Nitric Oxide Inhibit Airway Epithelial Cell Migration by Inhibition of the Kinase ERK1/2 and Activation of Hypoxia-inducible Factor-1α
Peter F. Bove, Milena Hristova, Umadevi V. Wesley et al. (6 authors)
Journal of Biological Chemistry
Open Access
Published: Apr 2008
45 citations
45 citations
6285 days before retraction
n-Propyl gallate activates hypoxia-inducible factor 1 by modulating intracellular oxygen-sensing systems
Motohide Kimura, Satoshi Takabuchi, Tomoharu Tanaka et al. (14 authors)
Biochemical Journal
Published: Mar 2008
24 citations
24 citations
6323 days before retraction
Mechanical signals modulated vascular endothelial growth factor-A (VEGF-A) alternative splicing in osteoblastic cells through actin polymerisation
Céline Faure, Marie‐Thérèse Linossier, Luc Malaval et al. (7 authors)
Bone
Open Access
Published: Mar 2008
48 citations
48 citations
6333 days before retraction
LPS Induces Hypoxia-Inducible Factor 1 Activation in Macrophage-Differentiated Cells in a Reactive Oxygen Species–Dependent Manner
Kenichiro Nishi, Tomoyuki Oda, Satoshi Takabuchi et al. (9 authors)
Antioxidants and Redox Signaling
Published: Jan 2008
151 citations
151 citations
6380 days before retraction
Biología molecular de los tumores corticales renales
Tobias Klatte, Allan J. Pantuck
Elsevier eBooks
Published: Jan 2008
6395 days before retraction
The Neurogenic Niche and Injury-Induced Neurogenesis.
Jennifer M. Plane
Unknown Journal
Published: Jan 2008
6395 days before retraction
Nitric Oxide in Tumor Angiogenesis
Lucia Morbidelli, Sandra Donnini, Marina Ziche
Angiogenesis
Published: Jan 2008
6395 days before retraction
<i>VHL</i>inactivation in renal cell carcinoma: implications for diagnosis, prognosis and treatment
W. Kimryn Rathmell, Shufen Chen
Expert Review of Anticancer Therapy
Open Access
Published: Dec 2007
77 citations
77 citations
6407 days before retraction
The mitochondrial thioredoxin system regulates nitric oxide-induced HIF-1α protein
Jie Zhou, Eleni Chantzoura, Giannis Spyrou et al. (4 authors)
Free Radical Biology and Medicine
Published: Oct 2007
27 citations
27 citations
6487 days before retraction
Integrative Pro-angiogenic Activation: HIF-α
Karen A. Vincent, Ralph A. Kelly
Springer eBooks
Published: Jun 2007
6583 days before retraction
Increased Endogenous Nitric Oxide Release by Iron Chelation and Purinergic Activation in the Rat Carotid Body
Man‐Lung Fung, Meifang Li, Sukhamay Lahiri
The Open Biochemistry Journal
Open Access
Published: Jun 2007
4 citations
4 citations
6595 days before retraction
The hypoxia‐inducible factor is stabilized in circulating hematopoietic stem cells under normoxic conditions
Cláudia Piccoli, Annamaria D’Aprile, Maria Ripoli et al. (7 authors)
FEBS Letters
Open Access
Published: Jun 2007
57 citations
57 citations
6604 days before retraction
Akt-Mediated Activation of HIF-1 in Pulmonary Vascular Endothelial Cells by S-Nitrosoglutathione
Deborah Jeannean Carver, Benjamin Gaston, Kimberly deRonde et al. (4 authors)
American Journal of Respiratory Cell and Molecular Biology
Open Access
Published: Jun 2007
44 citations
44 citations
6609 days before retraction
Hypoxia and Hypoxia-Inducible Factor-1 Expression Enhance Osteolytic Bone Metastases of Breast Cancer
Toru Hiraga, Shinae Kizaka‐Kondoh, Kiichi Hirota et al. (5 authors)
Cancer Research
Open Access
Published: May 2007
232 citations
232 citations
6640 days before retraction
Nitric oxide cell signaling: S-nitrosation of Ras superfamily GTPases
Kimberly W. Raines, Marcelo G. Bonini, Sharon L. Campbell
Cardiovascular Research
Open Access
Published: Apr 2007
62 citations
62 citations
6646 days before retraction
The transcription factor HIF-1α plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
Julian J. Lum, Thi Bui, Michaela Gruber et al. (8 authors)
Genes & Development
Open Access
Published: Apr 2007
403 citations
403 citations
6655 days before retraction
Promise and Progress for Functional and Molecular Imaging of Response to Targeted Therapies
Renu M. Stephen, Robert J. Gillies
Pharmaceutical Research
Published: Mar 2007
67 citations
67 citations
6679 days before retraction
Nitric oxide and superoxide: Interference with hypoxic signaling
Bernhard Brüne, Jiang‐Ning Zhou
Cardiovascular Research
Open Access
Published: Mar 2007
122 citations
122 citations
6687 days before retraction
Estrogen-Induced Activation of Hypoxia-Inducible Factor-1α, Vascular Endothelial Growth Factor Expression, and Edema in the Uterus Are Mediated by the Phosphatidylinositol 3-Kinase/Akt Pathway
Armina A. Kazi, Robert D. Koos
Endocrinology
Published: Feb 2007
127 citations
127 citations
6727 days before retraction
Hypoxia reduces the expression and anti-inflammatory effects of peroxisome proliferator-activated receptor- in human proximal renal tubular cells
X. Li, Hideki Kimura, Kiichi Hirota et al. (8 authors)
Nephrology Dialysis Transplantation
Open Access
Published: Jan 2007
37 citations
37 citations
6736 days before retraction
Cellular and Developmental Adaptations to Hypoxia: A Drosophila Perspective
Nuria M. Romero, Andrés Dekanty, Pablo Wappner
Methods in enzymology on CD-ROM/Methods in enzymology
Open Access
Published: Jan 2007
45 citations
45 citations
6760 days before retraction
Review Hypoxia-inducible factor (HIF) in human tumorigenesis
Sharon Amir
Unknown Journal
Published: Jan 2007
6760 days before retraction
Arginase, Nitric Oxide Synthase, and Novel Inhibitors of L-Arginine Metabolism in Immune Modulation
Susanna Mandruzzato, Simone Mocellin, Vincenzo Bronte
Elsevier eBooks
Published: Jan 2007
1 citation
1 citation
6760 days before retraction
Effects of oxygen on embryonic stem proliferation, energetics, and differentiation into cardiomyocytes
Daryl E. Powers
Unknown Journal
Published: Jan 2007
1 citation
1 citation
6760 days before retraction
Up-regulation of Hypoxia Inducible Factor 1α by Isoflurane in Hep3B Cells
Qi Fang Li, Xiang Rui Wang, Yue Wu Yang et al. (4 authors)
Anesthesiology
Open Access
Published: Nov 2006
61 citations
61 citations
6804 days before retraction
Hypertonic induction of aquaporin-5: novel role of hypoxia-inducible factor-1α
Beiyun Zhou, David K. Ann, Xian Li et al. (8 authors)
AJP Cell Physiology
Published: Nov 2006
42 citations
42 citations
6806 days before retraction
Nitric Oxide Modulates Oxygen Sensing by Hypoxia-inducible Factor 1-dependent Induction of Prolyl Hydroxylase 2
Utta Berchner‐Pfannschmidt, Hatice Yamac, Buena Trinidad et al. (4 authors)
Journal of Biological Chemistry
Open Access
Published: Oct 2006
151 citations
151 citations
6829 days before retraction
Nitric oxide, a double edged sword in cancer biology: Searching for therapeutic opportunities
Simone Mocellin, Vincenzo Bronte, Donato Nitti
Medicinal Research Reviews
Published: Sep 2006
453 citations
453 citations
6862 days before retraction
Activation of Ras Up-regulates Pro-apoptotic BNIP3 in Nitric Oxide-induced Cell Death
Hyun‐Jung An, Oky Maeng, Kyoung-Hee Kang et al. (7 authors)
Journal of Biological Chemistry
Open Access
Published: Sep 2006
51 citations
51 citations
6877 days before retraction
Hypoxia-Inducible Factor-1 (HIF-1)
Qingdong Ke, Max Costa
Molecular Pharmacology
Published: Aug 2006
1585 citations
1585 citations
6910 days before retraction
Natural Product-Derived Small Molecule Activators of Hypoxia-Inducible Factor-1 (HIF-1)
Dale G. Nagle, Yu‐Dong Zhou
Current Pharmaceutical Design
Open Access
Published: Jun 2006
66 citations
66 citations
6947 days before retraction
The role of nitric oxide in tumour progression
Dai Fukumura, Satoshi Kashiwagi, Rakesh K. Jain
Nature reviews. Cancer
Published: Jun 2006
1202 citations
1202 citations
6952 days before retraction
Regulation of angiogenesis by hypoxia-inducible factor 1
Kiichi Hirota, Gregg L. Semenza
Critical Reviews in Oncology/Hematology
Published: May 2006
460 citations
460 citations
6983 days before retraction
Role of Nitric Oxide in Cardiovascular Adaptation to Intermittent Hypoxia
Е. Б. Манухина, H. Fred Downey, Robert T. Mallet
Experimental Biology and Medicine
Published: Apr 2006
133 citations
133 citations
7035 days before retraction
Development of novel therapeutic strategies that target HIF-1
Gregg L. Semenza
Expert Opinion on Therapeutic Targets
Published: Mar 2006
123 citations
123 citations
7046 days before retraction
Induction of the nuclear factor HIF-1α in acetaminophen toxicity: Evidence for oxidative stress
Laura P. James, Brian Donahower, Angela S. Burke et al. (5 authors)
Biochemical and Biophysical Research Communications
Published: Mar 2006
34 citations
34 citations
7063 days before retraction
Activation of hypoxia-inducible factor 1 during macrophage differentiation
Tomoyuki Oda, Kiichi Hirota, Kenichiro Nishi et al. (12 authors)
AJP Cell Physiology
Open Access
Published: Feb 2006
124 citations
124 citations
7079 days before retraction
Calpain Mediates a von Hippel-Lindau Protein–independent Destruction of Hypoxia-inducible Factor-1α
Jie Zhou, Roman Köhl, Barbara Herr et al. (5 authors)
Molecular Biology of the Cell
Open Access
Published: Jan 2006
60 citations
60 citations
7107 days before retraction
Nitric Oxide Stimulates Vascular Endothelial Growth Factor Production in Cardiomyocytes Involved in Angiogenesis
Masanori Kuwabara, Yoshihiko Kakinuma, Motonori Ando et al. (7 authors)
The Journal of Physiological Sciences
Open Access
Published: Jan 2006
69 citations
69 citations
7125 days before retraction
Thyroid hormone mediated changes in gene expression can be initiated by cytosolic action of the thyroid hormone receptor β through the phosphatidylinositol 3-kinase pathway
Lars C. Moeller, Xia Cao, Alexandra M. Dumitrescu et al. (5 authors)
Nuclear Receptor Signaling
Open Access
Published: Jan 2006
134 citations
134 citations
7125 days before retraction
Quick Stats
Total Citations:
230
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 23, 2025