Retraction
Oligoprotective effect of metformin through the AMPK-dependent on restoration of mitochondrial hemostasis in the cuprizone-induced multiple sclerosis model
Paper Information
Record ID:
66124
Author(s):
Publication Date:
April 23, 2019
Retraction Date:
July 09, 2025
(<1 year years ago)
Subjects:
Institutions:
- Department of Anatomy, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
- Neuroscience Research Center, Iran University of Medical Sciences, Poursina Street, 1417613151, Tehran, Iran
- Institute of Neuroanatomy, Faculty of Medicine, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany
Countries:
Article Type:
Publisher:
Springer - Nature Publishing Group
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (31)
31
Total Citations0
Post-Retraction31
Pre-Retraction0
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Berberine-loaded iron oxide nanoparticles alleviate cuprizone-induced astrocytic reactivity in a rat model of multiple sclerosis
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Neuroprotective effects of rutin against cuprizone-induced multiple sclerosis in mice
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Published: Mar 2024
12 citations
12 citations
475 days before retraction
AMP‐activated protein kinase as a mediator of mitochondrial dysfunction of multiple sclerosis in animal models: A systematic review
Hamid Askari, Fatemeh Rabiei, Fatemeh Lohrasbi et al. (6 authors)
Journal of Cellular Physiology
Published: Feb 2024
3 citations
3 citations
500 days before retraction
A metformin add-on clinical study in multiple sclerosis to evaluate brain remyelination and neurodegeneration (MACSiMiSE-BRAIN): study protocol for a multi-center randomized placebo controlled clinical trial
Anna-Victoria De Keersmaecker, Eline Van Doninck, Veronica Popescu et al. (14 authors)
Frontiers in Immunology
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Published: Feb 2024
12 citations
12 citations
504 days before retraction
Age-dependent effects of metformin on human oligodendrocyte lineage cell ensheathment capacity
Abdulshakour Mohammadnia, Qiao‐Ling Cui, Chao Weng et al. (11 authors)
Brain Communications
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Published: Jan 2024
3 citations
3 citations
555 days before retraction
The impact of metformin use on the outcomes of relapse-remitting multiple sclerosis patients receiving interferon beta 1a: an exploratory prospective phase II open-label randomized controlled trial
Mohamed Y. Abdelgaied, Mohamed Hamed Rashad, Hend Mohamed El-Tayebi et al. (4 authors)
Journal of Neurology
Published: Dec 2023
7 citations
7 citations
578 days before retraction
The Roles of Caloric Restriction Mimetics in Central Nervous System Demyelination and Remyelination
Despoina Kaffe, Stefanos Ioannis Kaplanis, Domna Karagogeos
Current Issues in Molecular Biology
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Published: Nov 2023
1 citation
1 citation
590 days before retraction
Metformin treatment reduces inflammation, dysmyelination and disease severity in a mouse model of multiple sclerosis, experimental autoimmune encephalomyelitis
Emily Gilbert, Jessica Livingston, Emilio Garcia Flores et al. (6 authors)
Brain Research
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Published: Oct 2023
13 citations
13 citations
622 days before retraction
Promising use of metformin in treating neurological disorders: biomarker-guided therapies
Allison Loan, Charvi Syal, Margarita Lui et al. (5 authors)
Neural Regeneration Research
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Published: Sep 2023
19 citations
19 citations
656 days before retraction
The beneficial role of autophagy in multiple sclerosis: Yes or No?
Hayder M. Al‐kuraishy, Majid S. Jabir, Ali I. Al‐Gareeb et al. (6 authors)
Autophagy
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46 citations
46 citations
663 days before retraction
Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
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Drug Design Development and Therapy
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Published: Jun 2023
91 citations
91 citations
769 days before retraction
Deciphering crucial genes in multiple sclerosis pathogenesis and drug repurposing: A systems biology approach
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Journal of Proteomics
Published: Mar 2023
7 citations
7 citations
838 days before retraction
Metformin inhibits the pathogenic functions of AChR-specific B and Th17 cells by targeting miR-146a
Yue Hao, Wei Zhao, Lulu Chang et al. (16 authors)
Immunology Letters
Published: Sep 2022
3 citations
3 citations
1030 days before retraction
Nebivolol elicits a neuroprotective effect in the cuprizone model of multiple sclerosis in mice: emphasis on M1/M2 polarization and inhibition of NLRP3 inflammasome activation
Antoinette G. Naeem, Reem N. El‐Naga, Haidy E. Michel
Inflammopharmacology
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Published: Aug 2022
19 citations
19 citations
1064 days before retraction
Neuroprotective effect of liraglutide in an experimental mouse model of multiple sclerosis: role of AMPK/SIRT1 signaling and NLRP3 inflammasome
Reham A. Ammar, Ahmed F. Mohamed, Mohamed M. Kamal et al. (5 authors)
Inflammopharmacology
Open Access
Published: Apr 2022
56 citations
56 citations
1195 days before retraction
The mechanistic target of rapamycin as a regulator of metabolic function in oligodendroglia during remyelination
Marie L. Mather, Marisa A. Jeffries, Teresa L. Wood
Current Opinion in Pharmacology
Open Access
Published: Mar 2022
5 citations
5 citations
1226 days before retraction
Metformin Therapy Attenuates Pro-inflammatory Microglia by Inhibiting NF-κB in Cuprizone Demyelinating Mouse Model of Multiple Sclerosis
Mahdad Abdi, Parichehr Pasbakhsh, Maryam Shabani et al. (11 authors)
Neurotoxicity Research
Published: Sep 2021
34 citations
34 citations
1381 days before retraction
Progress in the Application of Drugs for the Treatment of Multiple Sclerosis
Weipeng Wei, Denglei Ma, Lin Li et al. (4 authors)
Frontiers in Pharmacology
Open Access
Published: Jul 2021
41 citations
41 citations
1457 days before retraction
Current status of neuroprotective and neuroregenerative strategies in multiple sclerosis: A systematic review
Jessica R. Allanach, John W Farrell, Miceline Mésidor et al. (4 authors)
Multiple Sclerosis Journal
Open Access
Published: Apr 2021
29 citations
29 citations
1542 days before retraction
Repurposing metformin to treat age-related neurodegenerative disorders and ischemic stroke
Sejal Sharma, Saeideh Nozohouri, Bhuvaneshwar Vaidya et al. (4 authors)
Life Sciences
Open Access
Published: Mar 2021
50 citations
50 citations
1580 days before retraction
Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders
Jan Spaas, Lieve van Veggel, Melissa Schepers et al. (13 authors)
Cellular and Molecular Life Sciences
Open Access
Published: Mar 2021
142 citations
142 citations
1582 days before retraction
Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system
Sarah Demaré, Asha Kothari, Nigel A. Calcutt et al. (4 authors)
Expert Review of Neurotherapeutics
Open Access
Published: Nov 2020
83 citations
83 citations
1703 days before retraction
Autophagy in white matter disorders of the <scp>CNS</scp>: mechanisms and therapeutic opportunities
Erik Nutma, Manuel Marzin, Saskia A.G.M. Cillessen et al. (4 authors)
The Journal of Pathology
Open Access
Published: Nov 2020
10 citations
10 citations
1710 days before retraction
Metformin as a Potential Agent in the Treatment of Multiple Sclerosis
Angela Dziedzic, Joanna Saluk, Elżbieta Miller et al. (4 authors)
International Journal of Molecular Sciences
Open Access
Published: Aug 2020
50 citations
50 citations
1785 days before retraction
The possible role of progranulin on anti-inflammatory effects of metformin in temporal lobe epilepsy
Somayeh Vazifehkhah, Ali Mohammad Khanizadeh, Tourandokht Balouchnejad Mojarad et al. (4 authors)
Journal of Chemical Neuroanatomy
Published: Jul 2020
25 citations
25 citations
1820 days before retraction
Mesenchymal Stem Cells Ameliorate Cuprizone-Induced Demyelination by Targeting Oxidative Stress and Mitochondrial Dysfunction
Elham Shiri, Parichehr Pasbakhsh, Maryam Borhani‐Haghighi et al. (10 authors)
Cellular and Molecular Neurobiology
Published: Jun 2020
39 citations
39 citations
1838 days before retraction
Metformin accelerates myelin recovery and ameliorates behavioral deficits in the animal model of multiple sclerosis via adjustment of AMPK/Nrf2/mTOR signaling and maintenance of endogenous oligodendrogenesis during brain self-repairing period
Nima Sanadgol, Mahmood Barati, Fariba Houshmand et al. (7 authors)
Pharmacological Reports
Published: Dec 2019
58 citations
58 citations
2030 days before retraction
Quick Stats
Total Citations:
31
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 23, 2025