Retraction
Epac1-Induced Cellular Proliferation in Prostate Cancer Cells Is Mediated by B-Raf/ERK and mTOR Signaling Cascades
Paper Information
Record ID:
66189
Author(s):
Journal:
Publication Date:
September 01, 2009
Retraction Date:
July 15, 2025
(<1 year years ago)
Subjects:
Country:
🇺🇸 United StatesArticle Type:
Publisher:
Wiley
Open Access:
Yes
DOI:
PubMed ID:
Retraction PubMed ID:
Retraction Details
Citations (65)
65
Total Citations0
Post-Retraction65
Pre-Retraction0
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1117 days before retraction
Evaluation of Rap1GAP and Epac1 Gene Expression in Endometriosis
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The Role of Neuropeptide-Stimulated cAMP-EPACs Signalling in Cancer Cells
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Glucagon transiently stimulates mTORC1 by activation of an EPAC/Rap1 signaling axis
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EPAC in Vascular Smooth Muscle Cells
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1820 days before retraction
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Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
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Cyclase-associated protein 1 (CAP1) is a prenyl-binding partner of Rap1 GTPase
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22 citations
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2659 days before retraction
Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development
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183 citations
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2680 days before retraction
Insights into exchange factor directly activated by cAMP (EPAC) as potential target for cancer treatment
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Overexpression of exchange protein directly activated by cAMP-1 (EPAC1) attenuates bladder cancer cell migration
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<scp>E</scp>pac1, <scp>PDE</scp>4, and <scp>PKC</scp> protein expression and their correlation with <scp>AKAP</scp>95 and <scp>C</scp>x43 in esophagus cancer tissues
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6 citations
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2903 days before retraction
Epac1, <scp>PDE</scp>4, and <scp>PKC</scp> protein expression and their association with <scp>AKAP</scp>95, <scp>C</scp>x43, and cyclin<scp>D</scp>2/<scp>E</scp>1 in breast cancer tissues
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Thoracic Cancer
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8 citations
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2908 days before retraction
EPAC1 overexpression is a prognostic marker and its inhibition shows promising therapeutic potential for gastric cancer
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Transporter effects on cell permeability in drug delivery
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Epac1 knockdown inhibits the proliferation of ovarian cancer cells by inactivating AKT/Cyclin D1/CDK4 pathway in vitro and in vivo
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Rap-Interacting Proteins are Key Players in the Rap Symphony Orchestra
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20 citations
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The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention
Muayad F. Almahariq, Fang Mei, Xiaodong Cheng
Acta Biochimica et Biophysica Sinica
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Published: Dec 2015
33 citations
33 citations
3492 days before retraction
Activated α2-Macroglobulin Binding to Human Prostate Cancer Cells Triggers Insulin-like Responses
Uma Kant Misra, Salvatore V. Pizzo
Journal of Biological Chemistry
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Published: Feb 2015
27 citations
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3791 days before retraction
Epac1 is involved in cell cycle progression in lung cancer through PKC and Cx43 regulation
Qian Sun, Dai Wang, Ganghao Ai et al. (13 authors)
Folia Histochemica et Cytobiologica
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3806 days before retraction
The Pharmacology of Nociceptor Priming
Ram Kandasamy, Theodore J. Price
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99 citations
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Pharmacological Inhibition and Genetic Knockdown of Exchange Protein Directly Activated by cAMP 1 Reduce Pancreatic Cancer Metastasis In Vivo
Muayad F. Almahariq, Celia Chao, Fang Mei et al. (7 authors)
Molecular Pharmacology
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51 citations
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3900 days before retraction
Paper citing Epac1-Induced Cellular Proliferation in Prostate C...
Unknown Authors
Unknown Journal
Published: Nov 2014
3905 days before retraction
Inhibition of soluble adenylyl cyclase increases the radiosensitivity of prostate cancer cells
Avinash Appukuttan, Jan-Paul Flacke, Hanna Flacke et al. (6 authors)
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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Published: Sep 2014
17 citations
17 citations
3948 days before retraction
Role of soluble adenylyl cyclase in cell death and growth
Yury Ladilov, Avinash Appukuttan
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
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47 citations
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4025 days before retraction
Activation of glucagon-like peptide-1 receptor inhibits growth and promotes apoptosis of human pancreatic cancer cells in a cAMP-dependent manner
Hejun Zhao, Rui Wei, Liang Wang et al. (11 authors)
AJP Endocrinology and Metabolism
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58 citations
58 citations
4087 days before retraction
Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain
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94 citations
94 citations
4261 days before retraction
Inhibition of protein translation as a novel mechanism for prostaglandin E <sub>2</sub> regulation of cell functions
Katsuhide Okunishi, Angela J. DeGraaf, Zbigniew Zasłona et al. (4 authors)
The FASEB Journal
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15 citations
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4310 days before retraction
Ras-mutant Cancer Cells Display B-Raf Binding to Ras That Activates Extracellular Signal-regulated Kinase and Is Inhibited by Protein Kinase A Phosphorylation
Yanping Li, Maho Takahashi, Philip A. Stork
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27 citations
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4371 days before retraction
The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction
Martin Hennenberg, Frank Strittmatter, Henning Schmetkamp et al. (7 authors)
Journal of Biomedical Science
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Published: Jul 2013
6 citations
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4396 days before retraction
The Monomeric Receptor Binding Domain of Tetrameric α<sub>2</sub>-Macroglobulin Binds to Cell Surface GRP78 Triggering Equivalent Activation of Signaling Cascades
Uma Kant Misra, Sturgis Payne, Salvatore V. Pizzo
Biochemistry
Published: May 2013
13 citations
13 citations
4439 days before retraction
Evidence for a Pro-Proliferative Feedback Loop in Prostate Cancer: The Role of Epac1 and COX-2-Dependent Pathways
Uma Kant Misra, Salvatore V. Pizzo
PLoS ONE
Open Access
Published: Apr 2013
33 citations
33 citations
4459 days before retraction
Paper citing Epac1-Induced Cellular Proliferation in Prostate C...
Unknown Authors
Unknown Journal
Published: Mar 2013
4519 days before retraction
cAMP-Regulated Cell Proliferation in Brown Preadipocytes
Yanling Wang
Unknown Journal
Published: Jan 2013
4578 days before retraction
iTorin1—An Active Site Inhibitor of mTOR, Suppresses Prostate Cancer Cell Growth Induced by Activated α2M-Macroglobulin Ligation of Cell Surface GRP78
Uma Kant Misra, Salvatore V. Pizzo
Journal of Cancer Therapy
Open Access
Published: Jan 2013
1 citation
1 citation
4578 days before retraction
Quick Stats
Total Citations:
65
Years Since Retraction:
<1 year
Open Access:
Yes
Last Checked:
Jul 23, 2025