Expression of concern
Ultra-low-dose naloxone suppresses opioid tolerance, dependence and associated changes in mu opioid receptor–G protein coupling and Gβγ signaling
Paper Information
Record ID:
36326
Author(s):
Journal:
Neuroscience
(
Elsevier
)
Publication Date:
August 05, 2005
Retraction Date:
December 20, 2021
(3.9 years years ago)
Subjects:
Institutions:
- Department of Physiology and Pharmacology, City University of New York Medical School, 138th Street and Convent Avenue, New York, NY 10031, USA
- Department of Psychology, Queen's University, Kingston, Ontario, K7L 3N6 Canada
- Pain Therapeutics, Inc., 416 Browning Way, South San Francisco, CA 94080, USA
Countries:
Article Type:
Publisher:
Elsevier
Open Access:
Yes
PubMed ID:
Retraction PubMed ID:
Expression of concern Details
Retraction Reason:
Nature of Retraction:
Expression of concern
Retraction Notice:
10.1016/j.neuroscience.2021.11.019Citations (172)
172
Total Citations12
Post-Retraction(7.0%)
159
Pre-Retraction0
Same DayPost-Retraction Citation Analysis
0
Within 30 days
3
Within 1 year
5
After 2+ years
1167
Days since retraction (latest)
High-Affinity Naloxone Binding to Filamin A Prevents Mu Opioid Receptor–Gs Coupling Underlying Opioid Tolerance and Dependence
Hoau-Yan Wang, Maya Frankfurt, Lindsay H. Burns
PLoS ONE
Open Access
Published: Feb 2008
80 citations
80 citations
5067 days before retraction
Ultra-Low-Dose Naloxone Restores the Antinociceptive Effect of Morphine and Suppresses Spinal Neuroinflammation in PTX-Treated Rats
Ru‐Yin Tsai, Fong-Lin Jang, Yueh-Hua Tai et al. (6 authors)
Neuropsychopharmacology
Open Access
Published: Jan 2008
52 citations
52 citations
5080 days before retraction
Morphine sex-dependently induced place conditioning in adult Wistar rats
Manizheh Karami, Mohammad‐Reza Zarrindast
European Journal of Pharmacology
Published: Dec 2007
74 citations
74 citations
5106 days before retraction
Administration of fentanyl before remifentanil‐based anaesthesia has no influence on post‐operative pain or analgesic consumption
Harald Lenz, Johan Ræder, Siv Cathrine Høymork
Acta Anaesthesiologica Scandinavica
Published: Nov 2007
23 citations
23 citations
5156 days before retraction
Ultra-Low Dose Antagonist Effects on Cannabinoids and Opioids in Models of Pain: Is Less More?
Jay Paquette
Unknown Journal
Published: Nov 2007
5156 days before retraction
Cannabinoid-induced tolerance is associated with a CB1 receptor G protein coupling switch that is prevented by ultra-low dose rimonabant
Jay Paquette, Hoau-Yan Wang, Kalindi Bakshi et al. (4 authors)
Behavioural Pharmacology
Published: Nov 2007
22 citations
22 citations
5157 days before retraction
Mechanisms of Opioid-Induced Tolerance and Hyperalgesia
Anna DuPen, Danny D. Shen, Mary Ersek
Pain Management Nursing
Published: Aug 2007
170 citations
170 citations
5230 days before retraction
Oxytrex<sup>®</sup>: an oxycodone and ultra-low-dose naltrexone formulation
Lynn R. Webster
Expert Opinion on Investigational Drugs
Published: Aug 2007
30 citations
30 citations
5255 days before retraction
Naloxone rapidly evokes endogenous kappa opioid receptor-mediated hyperalgesia in naïve mice pretreated briefly with GM1 ganglioside or in chronic morphine-dependent mice
Stanley M. Crain, Ke-Fei Shen
Brain Research
Published: Jul 2007
18 citations
18 citations
5270 days before retraction
Augmentation of spinal morphine analgesia and inhibition of tolerance by low doses of <i>μ‐</i> and <i>δ</i>‐opioid receptor antagonists
Noura S. Abul‐Husn, Maaja Sutak, Brian Milne et al. (4 authors)
British Journal of Pharmacology
Open Access
Published: May 2007
63 citations
63 citations
5334 days before retraction
Opioid dependence and addiction during opioid treatment of chronic pain
Jane C. Ballantyne, Steven K. LaForge
Pain
Published: May 2007
443 citations
443 citations
5341 days before retraction
Pharmacological approaches to the management of pain in the neonatal intensive care unit
K.J.S. Anand
Journal of Perinatology
Published: Apr 2007
116 citations
116 citations
5354 days before retraction
Inhibition of tolerance to spinal morphine antinociception by low doses of opioid receptor antagonists
Benjamin McNaull, Tuan Trang, Maaja Sutak et al. (4 authors)
European Journal of Pharmacology
Published: Jan 2007
34 citations
34 citations
5450 days before retraction
In My Opinion … Opioid Tolerance
Mark Collen
Journal of Pain & Palliative Care Pharmacotherapy
Published: Jan 2007
1 citation
1 citation
5467 days before retraction
Oxytrex Minimizes Physical Dependence While Providing Effective Analgesia: A Randomized Controlled Trial in Low Back Pain
Lynn R. Webster, P. Butera, Lauren V. Moran et al. (6 authors)
Journal of Pain
Open Access
Published: Dec 2006
135 citations
135 citations
5498 days before retraction
Effects of ultra-low doses of nicotine on the expression of morphine-induced conditioned place preference in mice
Jamal Shams, Hedayat Sahraei, Azam Gholami et al. (8 authors)
Behavioural Pharmacology
Published: Oct 2006
11 citations
11 citations
5558 days before retraction
Endogenous opiates and behavior: 2005
Richard J. Bodnar, Gad Klein
Peptides
Published: Sep 2006
78 citations
78 citations
5577 days before retraction
Gβγ that interacts with adenylyl cyclase in opioid tolerance originates from a Gs protein
Hoau‐Yan Wang, Lindsay H. Burns
Journal of Neurobiology
Published: Sep 2006
53 citations
53 citations
5579 days before retraction
Epidural naloxone reduces the incidence and severity of morphine-induced pruritus and nausea after total abdominal hysterectomy without affecting analgesia in patients receiving epidural post-operative analgesia with morphine and levobupivacaine
Maria Manolaraki, C. Apostolidis, Charalampos Stroumpos et al. (7 authors)
European Journal of Anaesthesiology
Published: Jun 2006
5681 days before retraction
Ultra-low-dose naltrexone reduces the rewarding potency of oxycodone and relapse vulnerability in rats
Francesco Leri, Lindsay H. Burns
Pharmacology Biochemistry and Behavior
Published: Sep 2005
61 citations
61 citations
5933 days before retraction
Ultra-low-dose naltrexone suppresses rewarding effects of opiates and aversive effects of opiate withdrawal in rats
Mary C. Olmstead, Lindsay H. Burns
Psychopharmacology
Published: Jul 2005
61 citations
61 citations
6006 days before retraction
Adding Ultralow-Dose Naltrexone to Oxycodone Enhances and Prolongs Analgesia: A Randomized, Controlled Trial of Oxytrex
Vishala Chindalore, Richard Craven, Kevin Yu et al. (6 authors)
Journal of Pain
Open Access
Published: Jun 2005
116 citations
116 citations
6046 days before retraction
Quick Stats
Total Citations:
172
Years Since Retraction:
3.9 years
Open Access:
Yes
Last Checked:
Jul 24, 2025